DK107391A - Isolering af foetale celler fra moderblod for at muliggoere diagnose foer foedslen - Google Patents

Isolering af foetale celler fra moderblod for at muliggoere diagnose foer foedslen Download PDF

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Publication number
DK107391A
DK107391A DK107391A DK107391A DK107391A DK 107391 A DK107391 A DK 107391A DK 107391 A DK107391 A DK 107391A DK 107391 A DK107391 A DK 107391A DK 107391 A DK107391 A DK 107391A
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Prior art keywords
pct
cells
isolation
maternal blood
fetal cells
Prior art date
Application number
DK107391A
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Danish (da)
English (en)
Other versions
DK107391D0 (da
Inventor
Utz Walter Mueller
Catherine Stella Hawes
Original Assignee
Flinders Technologies Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Flinders Technologies Pty Ltd filed Critical Flinders Technologies Pty Ltd
Publication of DK107391D0 publication Critical patent/DK107391D0/da
Publication of DK107391A publication Critical patent/DK107391A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK107391A 1988-12-06 1991-06-06 Isolering af foetale celler fra moderblod for at muliggoere diagnose foer foedslen DK107391A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPJ182488 1988-12-06
PCT/AU1989/000517 WO1990006509A1 (en) 1988-12-06 1989-11-29 Isolation of fetal cells from maternal blood to enable prenatal diagnosis

Publications (2)

Publication Number Publication Date
DK107391D0 DK107391D0 (da) 1991-06-06
DK107391A true DK107391A (da) 1991-07-31

Family

ID=3773565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK107391A DK107391A (da) 1988-12-06 1991-06-06 Isolering af foetale celler fra moderblod for at muliggoere diagnose foer foedslen

Country Status (11)

Country Link
US (1) US5503981A (de)
EP (1) EP0447424B1 (de)
JP (1) JP2935741B2 (de)
CN (1) CN1021257C (de)
AT (1) ATE161960T1 (de)
CA (1) CA2004592A1 (de)
DE (1) DE68928535T2 (de)
DK (1) DK107391A (de)
ES (1) ES2112833T3 (de)
NZ (1) NZ231621A (de)
WO (1) WO1990006509A1 (de)

Families Citing this family (54)

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US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US7115709B1 (en) * 1986-01-16 2006-10-03 The Regents Of The University Of California Methods of staining target chromosomal DNA employing high complexity nucleic acid probes
US5447841A (en) * 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US6344315B1 (en) 1986-01-16 2002-02-05 The Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
US6872817B1 (en) 1986-01-16 2005-03-29 The Regents Of The Univ. Of California Method of staining target interphase chromosomal DNA
US6475720B1 (en) 1986-01-16 2002-11-05 The Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
DE69032112T2 (de) * 1989-08-03 1998-07-09 Univ California Verfahren zur Isolierung von fetalen Zytotrophoblastzellen
JPH05501612A (ja) * 1989-11-13 1993-03-25 チルドレンズ・メデイカル・センター・コーポレーシヨン 胎児ｄｎａ単離および検出のための非侵入性方法
US5641628A (en) * 1989-11-13 1997-06-24 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
FR2682481A1 (fr) * 1991-10-11 1993-04-16 Saint Cy Scp Procede d'obtention de cellules trophoblastiques d'un fóoetus.
EP0610359A1 (de) * 1991-10-23 1994-08-17 Cellpro Incorporated Verfahren zur einrichtung fetaler stammzellen von mütterlichem blut
FR2685777A1 (fr) * 1991-12-31 1993-07-02 Bertin & Cie Procede de depistage prenatal d'anomalies fóoetales et procede de depistage prenatal du sexe.
DE4222573C1 (de) * 1992-05-16 1993-08-12 Dorothee Dr. 4400 Muenster De Ahlert
US5457024A (en) * 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
US5662813A (en) * 1994-10-21 1997-09-02 Bioseparations, Inc. Method for separation of nucleated fetal erythrocytes from maternal blood samples
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5801145A (en) * 1996-02-09 1998-09-01 Ontario Cancer Institute Method for selectively purging CD77+ cells from bone marrow
AUPO931997A0 (en) * 1997-09-22 1997-10-09 Flinders Technologies Pty Ltd Enrichment and identification of trophoblast cells in maternal peripheral blood
US6221596B1 (en) 1999-05-17 2001-04-24 Motobit Ltd. System and method for identifying and isolating rare cells from a mixed population of cells
WO2001007911A2 (en) * 1999-07-21 2001-02-01 Britta Christensen A novel method for the improved isolation of a target cell population
DE19964044C2 (de) * 1999-12-30 2001-11-22 Frank Hans Georg Verfahren zur Identifizierung von Substanzen, die Säugetier-Epitope nachahmen
WO2001049710A2 (de) * 1999-12-30 2001-07-12 Frank Hans Georg Verfahren zur identifizierung von substanzen, die säugetier-epitope nachahmen
US20020045196A1 (en) * 2000-05-12 2002-04-18 Walt Mahoney Methods of isolating trophoblast cells from maternal blood
US20050100951A1 (en) * 2000-10-26 2005-05-12 Biocept, Inc. 3D format biochips and method of use
RU2202790C2 (ru) * 2001-03-26 2003-04-20 Северный государственный медицинский университет Способ диагностики внутриутробного инфицирования плода
FR2824144B1 (fr) 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
EP1462800A4 (de) * 2001-12-11 2007-01-17 Netech Inc System zur trennung von blutzellen
NZ537328A (en) * 2002-05-31 2008-04-30 Genetic Technologies Ltd Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
RU2237897C2 (ru) * 2002-07-17 2004-10-10 ГУ "Ивановский научно-исследовательский институт материнства и детства им. В.Н.Городкова" Способ прогнозирования инфекционных заболеваний новорожденных
CA2500392C (en) 2002-09-27 2012-11-27 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
US20050181429A1 (en) * 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20040197832A1 (en) * 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
WO2005035725A2 (en) * 2003-10-08 2005-04-21 The Trustees Of Boston University Methods for prenatal diagnosis of chromosomal abnormalities
US7439062B2 (en) * 2004-12-23 2008-10-21 Biocept, Inc. Beads for capturing target cells from bodily fluid
FR2880897B1 (fr) 2005-01-18 2010-12-17 Inst Nat Sante Rech Med Methode de detection, non invasive, prenatale, in vitro de l'etat sain normal, de l'etat de porteur sain ou de l'etat de porteur malade de la mucoviscidose
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
EP2589668A1 (de) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
WO2007147074A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Use of highly parallel snp genotyping for fetal diagnosis
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US8338113B2 (en) 2007-05-01 2012-12-25 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods for detecting fetal cells in the maternal blood
WO2009103110A1 (en) * 2008-02-18 2009-08-27 Genetic Technologies Limited Cell processing and/or enrichment methods
HUE031848T2 (en) 2008-09-20 2017-08-28 Univ Leland Stanford Junior Non-invasive diagnosis of fetal aneuploidy by sequencing
US9447467B2 (en) 2009-04-21 2016-09-20 Genetic Technologies Limited Methods for obtaining fetal genetic material
EP2446267A1 (de) * 2009-06-24 2012-05-02 Health Corporation - Rambam Verfahren und kits zur isolation von plazentalen mikropartikeln und ihre verwendung zur diagnose von fetalen erkrankungen
CN101935700A (zh) * 2010-07-15 2011-01-05 浙江大学 鉴定绵羊早期胚胎性别的牙釉蛋白基因引物及其应用
WO2013192620A1 (en) 2012-06-22 2013-12-27 Quantrx Biomedical Corporation Method for obtaining fetal cells and fetal cellular components
CN103230416A (zh) * 2013-04-16 2013-08-07 中国人民解放军第三军医大学第三附属医院 一种小鼠合体滋养细胞微绒毛膜的制备方法及其应用
US10330680B2 (en) * 2014-10-10 2019-06-25 Wayne State University Methods of assaying RNA from fetal extravillous trophoblast cells isolated from a maternal endocervical sample
RU2695356C1 (ru) * 2018-11-14 2019-07-23 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Способ прогнозирования состояния плода при преждевременном разрыве плодных оболочек с 24 до 33 недель беременности
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
WO1990006509A1 (en) 1990-06-14
JPH04502060A (ja) 1992-04-09
CA2004592A1 (en) 1990-06-06
ES2112833T3 (es) 1998-04-16
US5503981A (en) 1996-04-02
JP2935741B2 (ja) 1999-08-16
ATE161960T1 (de) 1998-01-15
EP0447424A4 (en) 1992-06-24
NZ231621A (en) 1992-11-25
EP0447424A1 (de) 1991-09-25
DK107391D0 (da) 1991-06-06
EP0447424B1 (de) 1998-01-07
DE68928535T2 (de) 1998-04-16
CN1043788A (zh) 1990-07-11
DE68928535D1 (de) 1998-02-12
CN1021257C (zh) 1993-06-16

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