DK1075512T3 - Cytotoxinbaseret biologisk indkapsling - Google Patents
Cytotoxinbaseret biologisk indkapslingInfo
- Publication number
- DK1075512T3 DK1075512T3 DK99917812.2T DK99917812T DK1075512T3 DK 1075512 T3 DK1075512 T3 DK 1075512T3 DK 99917812 T DK99917812 T DK 99917812T DK 1075512 T3 DK1075512 T3 DK 1075512T3
- Authority
- DK
- Denmark
- Prior art keywords
- cytotoxin
- based biological
- biological encapsulation
- encapsulation
- biological
- Prior art date
Links
- 101710112752 Cytotoxin Proteins 0.000 title 1
- 231100000599 cytotoxic agent Toxicity 0.000 title 1
- 239000002619 cytotoxin Substances 0.000 title 1
- 238000005538 encapsulation Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/68—Stabilisation of the vector
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK62798 | 1998-05-07 | ||
| US8506798P | 1998-05-12 | 1998-05-12 | |
| PCT/DK1999/000258 WO1999058652A2 (en) | 1998-05-07 | 1999-05-07 | Cytotoxin-based biological containment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1075512T3 true DK1075512T3 (da) | 2010-06-07 |
Family
ID=26064343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99917812.2T DK1075512T3 (da) | 1998-05-07 | 1999-05-07 | Cytotoxinbaseret biologisk indkapsling |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7183097B1 (da) |
| EP (2) | EP2180050B1 (da) |
| AU (1) | AU766257C (da) |
| CA (1) | CA2327387C (da) |
| DE (1) | DE69942249D1 (da) |
| DK (1) | DK1075512T3 (da) |
| WO (1) | WO1999058652A2 (da) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7176029B2 (en) | 1992-07-31 | 2007-02-13 | Universite Libre De Bruxelles | Cloning and/or sequencing vector |
| BE1006085A3 (fr) | 1992-07-31 | 1994-05-10 | Univ Bruxelles | Vecteur de clonage. |
| GB9916810D0 (en) * | 1999-07-16 | 1999-09-22 | Cancer Res Campaign Tech | Killing cells |
| US6365129B1 (en) | 1999-08-04 | 2002-04-02 | Tosk, Inc. | Invivo high throughput toxicology screening method |
| ATE439372T1 (de) * | 2000-10-27 | 2009-08-15 | Novartis Vaccines & Diagnostic | Nukleinsäuren und proteine von gruppen a und b- streptokokken |
| CA2435956C (en) | 2001-02-23 | 2012-07-10 | Universite Libre De Bruxelles | Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule |
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| US20090215179A1 (en) * | 2001-07-20 | 2009-08-27 | Transalgae | Transgenically preventing establishment and spread of transgenic algae in natural ecosystems |
| AU2002366977A1 (en) | 2002-01-02 | 2003-07-30 | Jemtex Ink Jet Printing Ltd. | Ink jet printing apparatus |
| US20050260585A1 (en) * | 2002-03-19 | 2005-11-24 | Cedric Szpirer | Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms |
| WO2004001020A2 (en) | 2002-06-19 | 2003-12-31 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Methods and means to promote gut absorption |
| US9309518B2 (en) | 2002-09-03 | 2016-04-12 | Universite Libre De Bruxelles | Reversible, parallel and multitask cloning method and kit |
| AU2003260200A1 (en) | 2002-09-03 | 2004-03-29 | Universite Libre De Bruxelles | Reversible, parallel and multitask cloning method and kit |
| US7491699B2 (en) | 2002-12-09 | 2009-02-17 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures and methods of generating and using the same |
| EP1583713B1 (en) | 2003-01-07 | 2009-03-25 | Ramot at Tel Aviv University Ltd. | Peptide nanostructures encapsulating a foreign material and method of manufacturing same |
| JP2007527728A (ja) | 2003-04-03 | 2007-10-04 | ガリル メディカル リミテッド | 正確に画定された冷凍切除のための装置及び方法 |
| WO2005027901A1 (en) | 2003-09-25 | 2005-03-31 | Tel Aviv University Future Technology Development L.P. | Compositions and methods using same for treating amyloid-associated diseases |
| WO2005031362A2 (en) * | 2003-10-02 | 2005-04-07 | Ramot At Tel Aviv University Ltd. | Novel antibacterial agents and methods of identifying and utilizing same |
| WO2006013552A2 (en) | 2004-08-02 | 2006-02-09 | Ramot At Tel Aviv University Ltd. | Articles of peptide nanostructures and method of forming the same |
| US7732479B2 (en) | 2004-08-19 | 2010-06-08 | Tel Aviv University Future Technology Development L.P. | Compositions for treating amyloid associated diseases |
| WO2007024991A2 (en) * | 2005-08-24 | 2007-03-01 | University Of Medicine And Dentistry Of New Jersey | Inhibition of mrna interferase-induced apoptosis in bak-deficient and bak-and bax-deficient mammalian cells |
| EP1973928A2 (en) | 2005-10-11 | 2008-10-01 | Ramot at Tel-Aviv University Ltd. | Self-assembled fmoc-ff hydrogels |
| AU2006319216B2 (en) | 2005-11-29 | 2012-09-13 | Intrexon Actobiotics Nv | Induction of mucosal tolerance to antigens |
| EP3351268B1 (en) | 2007-01-25 | 2020-08-05 | Intrexon Actobiotics NV | Treatment of immune disease by mucosal delivery of antigens |
| CA2730741C (en) | 2008-07-18 | 2016-10-25 | Regis Sodoyer | Self-replicating vector lacking an antibiotic-resistance gene |
| US8367392B2 (en) * | 2008-09-05 | 2013-02-05 | Transalgae Ltd. | Genetic transformation of algal and cyanobacteria cells by microporation |
| EP2384366A4 (en) * | 2008-09-05 | 2012-10-24 | Jonathan Gressel | TRANSGENIC PREVENTION OF THE ESTABLISHMENT AND PROPAGATION OF TRANSGENIC ALGAE IN NATURAL ECOSYSTEMS |
| US20110081706A1 (en) * | 2009-10-02 | 2011-04-07 | TransAlgae Ltd | Method and system for efficient harvesting of microalgae and cyanobacteria |
| US9005977B2 (en) | 2010-09-21 | 2015-04-14 | Joule Unlimited Technologies, Inc. | Methods and compositions for limiting viability of a modified host cell outside of designated process conditions |
| MX2013015327A (es) | 2011-06-30 | 2014-01-31 | Exxonmobil Res & Eng Co | Regulacion de genes toxina y antitoxina para contencion biologica. |
| US9670504B2 (en) | 2011-07-08 | 2017-06-06 | Cilbiotech S.A. | Transgenic system for reversibly immortalizing mammalian quiescent cells |
| WO2013067326A1 (en) * | 2011-11-04 | 2013-05-10 | University Of Georgia Research Foundation, Inc | Methods for expressing polypeptides in hyperthermophiles |
| PT2814508T (pt) | 2012-02-14 | 2017-07-19 | Merial Inc | Vacinas de subunidades de rotavírus e métodos para as produzir e uso das mesmas |
| WO2014145346A2 (en) * | 2013-03-15 | 2014-09-18 | Bacterial Robotics, Llc | Compositions, systems and methods for protecting genetically modified organisms from unauthorized use or release into the environment |
| BR112016003533B1 (pt) | 2013-08-19 | 2021-11-03 | Syngulon Sa | Célula microbiana geneticamente modificada e método para controlar o crescimento de uma segunda célula microbiana em um meio de cultura |
| WO2015118541A1 (en) * | 2014-02-05 | 2015-08-13 | Gavish-Galilee Bio Applications Ltd | A genetic system for generating conditionally inactivated or attenuated bacteria |
| CN106715681B (zh) | 2014-07-25 | 2021-08-24 | R·P·谢勒科技有限责任公司 | 用于生产蛋白质的经改进的宿主细胞 |
| WO2016073079A2 (en) * | 2014-09-26 | 2016-05-12 | Yale University | Compositions and methods for biocontainment of microorganisms |
| EP3217807A4 (en) | 2014-11-11 | 2018-09-12 | Clara Foods Co. | Methods and compositions for egg white protein production |
| CN111212569B (zh) | 2017-08-31 | 2025-01-24 | 辛格隆股份公司 | 用于制备细菌素和抗微生物肽的方法和组合物 |
| MY195280A (en) | 2017-09-08 | 2023-01-12 | New Portal Ltd | Nucleic Acid Systems That Enable Bacteria to Specifically Target Solid Tumors Via Glucose-Dependent Viability |
| CA3084954A1 (en) | 2017-12-05 | 2019-06-13 | BioPlx, Inc. | Methods and compositions to prevent microbial infection |
| WO2019121983A1 (en) | 2017-12-19 | 2019-06-27 | Syngulon S.A. | Fermentation process |
| BR112020024767A2 (pt) | 2018-06-06 | 2021-03-23 | Syngulon Sa | engenharia de peptídeos antimicrobianos |
| SI3997118T1 (sl) | 2019-07-11 | 2025-06-30 | Clara Foods Co. | Sestavek napitka, ki obsega rekombinantni ovomukoidni protein |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| US11149280B2 (en) | 2019-10-29 | 2021-10-19 | Yale University | Engineering organisms resistant to viruses and horizontally transferred genetic elements |
| CN111429969A (zh) * | 2020-03-31 | 2020-07-17 | 中国人民解放军军事科学院军事医学研究院 | 一种细菌中功能性前噬菌体及其位置与序列的检测方法 |
| WO2022006748A1 (en) | 2020-07-07 | 2022-01-13 | New Portal Limited | Genetically engineered live bacteria and methods of constructing the same |
| CN118374547A (zh) * | 2023-01-13 | 2024-07-23 | 上海吉量医药工程有限公司 | 一种无抗微质粒及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE107697T1 (de) * | 1986-03-26 | 1994-07-15 | Genexpress Aps | Biologische eindämmung. |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5300431A (en) | 1991-02-26 | 1994-04-05 | E. I. Du Pont De Nemours And Company | Positive selection vector for the bacteriophage P1 cloning system |
| US7176029B2 (en) | 1992-07-31 | 2007-02-13 | Universite Libre De Bruxelles | Cloning and/or sequencing vector |
| BE1006085A3 (fr) | 1992-07-31 | 1994-05-10 | Univ Bruxelles | Vecteur de clonage. |
| CA2173751A1 (en) | 1993-10-13 | 1995-04-20 | Sýren Molin | Recombinant staphylococcal nucleases and their use in limiting the survival of genetically engineered microorganisms |
| JP2590761B2 (ja) | 1994-11-22 | 1997-03-12 | 日本電気株式会社 | Tab式半導体装置およびtab式半導体装置を回路基板に接続する方法 |
| NZ500843A (en) | 1995-06-07 | 2002-03-28 | Invitrogen Corp | A method of DNA recombination which is selectable to select for cells containing a product and against cells only harbouring the insert donor |
| US6143557A (en) | 1995-06-07 | 2000-11-07 | Life Technologies, Inc. | Recombination cloning using engineered recombination sites |
| NZ322673A (en) | 1995-10-13 | 1999-09-29 | Purdue Research Foundation | Method for the production of hybrid plants |
| US5922583A (en) | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
| JP4303418B2 (ja) | 1997-10-24 | 2009-07-29 | ライフ テクノロジーズ コーポレーション | 組換え部位を有する核酸を使用する組換えクローニング |
| US6271359B1 (en) | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| NZ529476A (en) | 1999-10-25 | 2005-03-24 | Invitrogen Corp | Methods of manipulating and sequencing nucleic acid molecules using transposition and recombination |
| CN1757724B (zh) | 1999-12-10 | 2014-06-11 | 茵维特罗根公司 | 具有独特特异性的多个重组位点在重组克隆中的用途 |
| EP1111061A1 (en) | 1999-12-20 | 2001-06-27 | Universite Libre De Bruxelles | Double selection vector |
| DE10038573A1 (de) | 2000-08-03 | 2002-02-21 | Mpb Cologne Gmbh Molecular Pla | Verfahren zur Selektion auf Wirtszellen mit eliminierten DNA-Sequenzen |
| CA2435956C (en) | 2001-02-23 | 2012-07-10 | Universite Libre De Bruxelles | Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule |
| US20050260585A1 (en) | 2002-03-19 | 2005-11-24 | Cedric Szpirer | Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms |
| AU2003260200A1 (en) | 2002-09-03 | 2004-03-29 | Universite Libre De Bruxelles | Reversible, parallel and multitask cloning method and kit |
| US20050130306A1 (en) * | 2003-12-10 | 2005-06-16 | Richard Voellmy | Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small molecule regulator |
-
1999
- 1999-05-07 EP EP09168998.4A patent/EP2180050B1/en not_active Expired - Lifetime
- 1999-05-07 DK DK99917812.2T patent/DK1075512T3/da active
- 1999-05-07 DE DE69942249T patent/DE69942249D1/de not_active Expired - Lifetime
- 1999-05-07 EP EP99917812A patent/EP1075512B1/en not_active Expired - Lifetime
- 1999-05-07 US US09/700,130 patent/US7183097B1/en not_active Expired - Lifetime
- 1999-05-07 CA CA2327387A patent/CA2327387C/en not_active Expired - Lifetime
- 1999-05-07 WO PCT/DK1999/000258 patent/WO1999058652A2/en not_active Ceased
- 1999-05-07 AU AU35963/99A patent/AU766257C/en not_active Expired
-
2006
- 2006-11-10 US US11/558,856 patent/US7595185B2/en not_active Expired - Fee Related
-
2007
- 2007-08-10 US US11/837,456 patent/US7595186B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20080182327A1 (en) | 2008-07-31 |
| AU766257B2 (en) | 2003-10-09 |
| EP1075512A2 (en) | 2001-02-14 |
| CA2327387C (en) | 2012-07-03 |
| EP2180050A3 (en) | 2010-06-30 |
| EP2180050B1 (en) | 2016-04-20 |
| DE69942249D1 (de) | 2010-05-27 |
| US7183097B1 (en) | 2007-02-27 |
| WO1999058652A2 (en) | 1999-11-18 |
| EP2180050A2 (en) | 2010-04-28 |
| AU766257C (en) | 2004-06-03 |
| US7595185B2 (en) | 2009-09-29 |
| EP1075512B1 (en) | 2010-04-14 |
| AU3596399A (en) | 1999-11-29 |
| US7595186B2 (en) | 2009-09-29 |
| CA2327387A1 (en) | 1999-11-08 |
| US20080206840A1 (en) | 2008-08-28 |
| WO1999058652A3 (en) | 2000-01-20 |
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