DK1105507T3 - Overekspression af önskede proteiner i eukaryote celler medieret af cyclin D1-overekspression - Google Patents

Overekspression af önskede proteiner i eukaryote celler medieret af cyclin D1-overekspression

Info

Publication number: DK1105507T3
Authority: DK; Denmark
Prior art keywords: protein; interest; cyclin; overexpression; nucleic acid
Prior art date: 1998-08-11

Application number

DK99942098T

Other languages

English (en)

Inventor

Shaw-Fen Sylvia Hu

Jean Marie Gudas

David William Brankow

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-11

Filing date

1999-08-11

Publication date

2007-11-05

1999-08-11 Application filed by Amgen Inc filed Critical Amgen Inc

2007-11-05 Application granted granted Critical

2007-11-05 Publication of DK1105507T3 publication Critical patent/DK1105507T3/da

Links

108090000623 proteins and genes Proteins 0.000 title abstract 9
102000004169 proteins and genes Human genes 0.000 title abstract 9
210000003527 eukaryotic cell Anatomy 0.000 title abstract 3
230000002018 overexpression Effects 0.000 title 2
102000006311 Cyclin D1 Human genes 0.000 title 1
108010058546 Cyclin D1 Proteins 0.000 title 1
230000001404 mediated effect Effects 0.000 title 1
108090000259 Cyclin D Proteins 0.000 abstract 4
102000039446 nucleic acids Human genes 0.000 abstract 4
108020004707 nucleic acids Proteins 0.000 abstract 4
150000007523 nucleic acids Chemical class 0.000 abstract 4
210000004027 cell Anatomy 0.000 abstract 3
108010019673 Darbepoetin alfa Proteins 0.000 abstract 2
108090000394 Erythropoietin Proteins 0.000 abstract 2
102000003951 Erythropoietin Human genes 0.000 abstract 2
102000008108 Osteoprotegerin Human genes 0.000 abstract 2
108010035042 Osteoprotegerin Proteins 0.000 abstract 2
229940105423 erythropoietin Drugs 0.000 abstract 2
229940039781 leptin Drugs 0.000 abstract 2
XXUPLYBCNPLTIW-UHFFFAOYSA-N octadec-7-ynoic acid Chemical compound CCCCCCCCCCC#CCCCCCC(O)=O XXUPLYBCNPLTIW-UHFFFAOYSA-N 0.000 abstract 2
OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 2
102000016267 Leptin Human genes 0.000 abstract 1
108010092277 Leptin Proteins 0.000 abstract 1
-1 OPG-Fc Chemical compound 0.000 abstract 1
210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Cell Biology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

DK99942098T 1998-08-11 1999-08-11 Overekspression af önskede proteiner i eukaryote celler medieret af cyclin D1-overekspression DK1105507T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US9608698P	1998-08-11	1998-08-11
US09/371,309 US6210924B1 (en)	1998-08-11	1999-08-10	Overexpressing cyclin D 1 in a eukaryotic cell line
PCT/US1999/018213 WO2000009714A1 (en)	1998-08-11	1999-08-11	Overexpression of desired proteins in eukaryotic cells mediated by cyclin d1 overexpression

Publications (1)

Publication Number	Publication Date
DK1105507T3 true DK1105507T3 (da)	2007-11-05

Family

ID=22255220

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99942098T DK1105507T3 (da)	1998-08-11	1999-08-11	Overekspression af önskede proteiner i eukaryote celler medieret af cyclin D1-overekspression

Country Status (15)

Country	Link
US (1)	US6210924B1 (da)
EP (1)	EP1105507B1 (da)
JP (1)	JP4562915B2 (da)
KR (1)	KR100502701B1 (da)
CN (1)	CN1151263C (da)
AT (1)	ATE374827T1 (da)
AU (1)	AU747640B2 (da)
CA (1)	CA2338820C (da)
CY (1)	CY1106987T1 (da)
DE (1)	DE69937243T2 (da)
DK (1)	DK1105507T3 (da)
ES (1)	ES2291038T3 (da)
HU (1)	HU230247B1 (da)
PT (1)	PT1105507E (da)
WO (1)	WO2000009714A1 (da)

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JP7628764B2 (ja)	2015-09-29	2025-02-12	アムジエン・インコーポレーテツド	Ａｓｇｒ阻害剤
US11261462B2 (en)	2016-01-27	2022-03-01	Just-Evotec Biologics, Inc.	Inducible expression from transposon-based vectors and uses
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1999
- 1999-08-10 US US09/371,309 patent/US6210924B1/en not_active Expired - Lifetime
- 1999-08-11 PT PT99942098T patent/PT1105507E/pt unknown
- 1999-08-11 DE DE69937243T patent/DE69937243T2/de not_active Expired - Lifetime
- 1999-08-11 AU AU55546/99A patent/AU747640B2/en not_active Expired
- 1999-08-11 ES ES99942098T patent/ES2291038T3/es not_active Expired - Lifetime
- 1999-08-11 CN CNB998118990A patent/CN1151263C/zh not_active Expired - Lifetime
- 1999-08-11 WO PCT/US1999/018213 patent/WO2000009714A1/en not_active Ceased
- 1999-08-11 KR KR10-2001-7001843A patent/KR100502701B1/ko not_active Expired - Lifetime
- 1999-08-11 CA CA002338820A patent/CA2338820C/en not_active Expired - Lifetime
- 1999-08-11 DK DK99942098T patent/DK1105507T3/da active
- 1999-08-11 JP JP2000565148A patent/JP4562915B2/ja not_active Expired - Lifetime
- 1999-08-11 HU HU0103485A patent/HU230247B1/hu unknown
- 1999-08-11 AT AT99942098T patent/ATE374827T1/de active
- 1999-08-11 EP EP99942098A patent/EP1105507B1/en not_active Expired - Lifetime
2007
- 2007-11-08 CY CY20071101438T patent/CY1106987T1/el unknown

Also Published As

Publication number	Publication date
PT1105507E (pt)	2007-12-07
JP2003524378A (ja)	2003-08-19
WO2000009714A1 (en)	2000-02-24
HU230247B1 (hu)	2015-11-30
KR20020013462A (ko)	2002-02-20
DE69937243D1 (de)	2007-11-15
CA2338820A1 (en)	2000-02-24
HUP0103485A2 (hu)	2002-01-28
CY1106987T1 (el)	2012-09-26
ATE374827T1 (de)	2007-10-15
US6210924B1 (en)	2001-04-03
AU5554699A (en)	2000-03-06
DE69937243T2 (de)	2008-07-03
ES2291038T3 (es)	2008-02-16
JP4562915B2 (ja)	2010-10-13
AU747640B2 (en)	2002-05-16
WO2000009714A9 (en)	2000-05-18
KR100502701B1 (ko)	2005-07-22
CN1151263C (zh)	2004-05-26
EP1105507B1 (en)	2007-10-03
CA2338820C (en)	2005-10-18
HUP0103485A3 (en)	2010-01-28
EP1105507A1 (en)	2001-06-13
CN1322253A (zh)	2001-11-14

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