DK1106612T3 - Quinolinderivater, der er nyttige til inhibering af farnesylproteintransferase - Google Patents

Quinolinderivater, der er nyttige til inhibering af farnesylproteintransferase

Info

Publication number
DK1106612T3
DK1106612T3 DK00309627T DK00309627T DK1106612T3 DK 1106612 T3 DK1106612 T3 DK 1106612T3 DK 00309627 T DK00309627 T DK 00309627T DK 00309627 T DK00309627 T DK 00309627T DK 1106612 T3 DK1106612 T3 DK 1106612T3
Authority
DK
Denmark
Prior art keywords
protein transferase
farnesyl protein
compounds
derivatives useful
quinoline derivatives
Prior art date
Application number
DK00309627T
Other languages
English (en)
Inventor
Bingwei Vera Yang
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1106612T3 publication Critical patent/DK1106612T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK00309627T 1999-11-30 2000-11-01 Quinolinderivater, der er nyttige til inhibering af farnesylproteintransferase DK1106612T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16820799P 1999-11-30 1999-11-30
US17011999P 1999-12-10 1999-12-10

Publications (1)

Publication Number Publication Date
DK1106612T3 true DK1106612T3 (da) 2004-05-17

Family

ID=26863889

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00309627T DK1106612T3 (da) 1999-11-30 2000-11-01 Quinolinderivater, der er nyttige til inhibering af farnesylproteintransferase

Country Status (12)

Country Link
US (1) US6596735B1 (da)
EP (1) EP1106612B1 (da)
JP (1) JP2001213876A (da)
AT (1) ATE259365T1 (da)
BR (1) BR0005633A (da)
CA (1) CA2327026A1 (da)
DE (1) DE60008206T2 (da)
DK (1) DK1106612T3 (da)
ES (1) ES2212971T3 (da)
MX (1) MXPA00011856A (da)
PT (1) PT1106612E (da)
TR (1) TR200400342T4 (da)

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CN105873439A (zh) 2013-10-15 2016-08-17 詹森药业有限公司 RORγt的烷基连接的喹啉基调节剂
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
KR20160068956A (ko) 2013-10-15 2016-06-15 얀센 파마슈티카 엔.브이. RORyT의 퀴놀리닐 조절제
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TW349948B (en) * 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
EE03484B1 (et) * 1995-12-08 2001-08-15 Janssen Pharmaceutica N.V. Farnesüülproteiintransferaasi inhibeerivad (5-imidasolüül)metüül-2-kinolinooni derivaadid ja nende kasutamine
TW591030B (en) * 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
ATE222104T1 (de) * 1997-06-02 2002-08-15 Janssen Pharmaceutica Nv (imidazol-5-yl)methyl-2-quinolinone derivativen als inhibitoren von proliferation der glatten muskelzellen
HRP20000904A2 (en) * 1998-07-06 2001-12-31 Janssen Pharmaceutica Nv Farnesyl protein transferase inhibitors for treating arthropathies
KR20010102073A (ko) * 1999-02-11 2001-11-15 실버스타인 아써 에이. 항암제로 유용한 헤테로아릴-치환된 퀴놀린-2-온 유도체

Also Published As

Publication number Publication date
TR200400342T4 (tr) 2004-03-22
JP2001213876A (ja) 2001-08-07
US6596735B1 (en) 2003-07-22
DE60008206T2 (de) 2004-12-02
DE60008206D1 (de) 2004-03-18
ES2212971T3 (es) 2004-08-16
CA2327026A1 (en) 2001-05-30
ATE259365T1 (de) 2004-02-15
MXPA00011856A (es) 2002-06-04
BR0005633A (pt) 2001-07-17
EP1106612A1 (en) 2001-06-13
PT1106612E (pt) 2004-06-30
EP1106612B1 (en) 2004-02-11

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