DK1110554T3 - Medicinal præparater til behandling af öjensygdomme - Google Patents

Medicinal præparater til behandling af öjensygdomme

Info

Publication number
DK1110554T3
DK1110554T3 DK99940582T DK99940582T DK1110554T3 DK 1110554 T3 DK1110554 T3 DK 1110554T3 DK 99940582 T DK99940582 T DK 99940582T DK 99940582 T DK99940582 T DK 99940582T DK 1110554 T3 DK1110554 T3 DK 1110554T3
Authority
DK
Denmark
Prior art keywords
eye diseases
medications
treatment
compositions
ocular tension
Prior art date
Application number
DK99940582T
Other languages
English (en)
Inventor
Toichi Abiru
Kazuki Endo
Tomokazu Hosokawa
Miwa Misawa
Takashi Konno
Original Assignee
Yamasa Corp
Toa Eiyo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Corp, Toa Eiyo Ltd filed Critical Yamasa Corp
Application granted granted Critical
Publication of DK1110554T3 publication Critical patent/DK1110554T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK99940582T 1998-09-01 1999-08-31 Medicinal præparater til behandling af öjensygdomme DK1110554T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24682698A JP2002173427A (ja) 1998-09-01 1998-09-01 眼疾患治療用医薬組成物

Publications (1)

Publication Number Publication Date
DK1110554T3 true DK1110554T3 (da) 2006-04-10

Family

ID=17154279

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99940582T DK1110554T3 (da) 1998-09-01 1999-08-31 Medicinal præparater til behandling af öjensygdomme

Country Status (11)

Country Link
US (1) US6387889B1 (da)
EP (1) EP1110554B1 (da)
JP (1) JP2002173427A (da)
CN (1) CN1151794C (da)
AT (1) ATE319458T1 (da)
AU (1) AU5446299A (da)
CA (1) CA2342204A1 (da)
DE (1) DE69930271T8 (da)
DK (1) DK1110554T3 (da)
ES (1) ES2259842T3 (da)
WO (1) WO2000012098A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE263777T1 (de) * 1999-02-01 2004-04-15 Univ Virginia Zusammensetzungen zur behandlung von entzündungsreaktionen
US6232297B1 (en) * 1999-02-01 2001-05-15 University Of Virginia Patent Foundation Methods and compositions for treating inflammatory response
US7378400B2 (en) * 1999-02-01 2008-05-27 University Of Virginia Patent Foundation Method to reduce an inflammatory response from arthritis
US7427606B2 (en) * 1999-02-01 2008-09-23 University Of Virginia Patent Foundation Method to reduce inflammatory response in transplanted tissue
ES2173027B2 (es) * 2000-07-06 2005-12-16 Universidad Complutense De Madrid Uso de nucleotidos en el tratamiento del glaucoma y la hipertension ocular.
EP1316559B1 (en) * 2000-09-08 2004-11-03 Toa Eiyo Ltd. Adenosine derivatives and use thereof
AU2001278708A1 (en) 2000-09-08 2002-03-22 Toa Eiyo Ltd. Adenosine derivatives and use thereof
SG176313A1 (en) * 2001-10-01 2011-12-29 Univ Virginia Patent Found 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof
EP1496911B1 (en) * 2002-04-10 2007-12-19 University Of Virginia Patent Foundation Use of a combination comprising a2a adenosine receptor agonists and anti-pathogenic agents for the treatment of inflammatory diseases
EP1740587A4 (en) * 2004-04-02 2009-07-15 Adenosine Therapeutics Llc SELECTIVE ANTAGONISTS OF A2A ADENOSINE RECEPTORS
TWI346109B (en) 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
US7576069B2 (en) * 2004-08-02 2009-08-18 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs having A2A agonist activity
WO2006023272A1 (en) * 2004-08-02 2006-03-02 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs having a2a agonist activity
CA2576826C (en) * 2004-08-02 2014-09-30 University Of Virginia Patent Foundation 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity
US8178509B2 (en) 2006-02-10 2012-05-15 University Of Virginia Patent Foundation Method to treat sickle cell disease
US8188063B2 (en) 2006-06-19 2012-05-29 University Of Virginia Patent Foundation Use of adenosine A2A modulators to treat spinal cord injury
WO2008133129A1 (ja) * 2007-04-16 2008-11-06 Santen Pharmaceutical Co., Ltd. アデノシンａ２ａ受容体アゴニストを有効成分として含有する緑内障治療剤
US8058259B2 (en) 2007-12-20 2011-11-15 University Of Virginia Patent Foundation Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists
EA201200635A1 (ru) * 2009-10-26 2012-10-30 Инотек Фармасьютикалз Корпорейшн Глазной состав и способ его изготовления
MX367879B (es) 2012-08-01 2019-09-10 Lewis And Clark Pharmaceuticals Inc N-alquil 2-(disustituido)alquiladenosin-5-uronamidas como agonistas a2a.
US9822141B2 (en) 2012-08-01 2017-11-21 Lewis And Clark Pharmaceuticals, Inc. N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as A2A agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106983B2 (ja) * 1987-12-02 1995-11-15 三共株式会社 グリゼオール酸ジエステル誘導体
DE68916036T2 (de) * 1988-11-15 1994-09-29 Toa Eiyo Ltd Mittel zur behandlung und prophylaxe koronarer und zerebraler ischämischer erkrankungen.
US5039797A (en) * 1989-10-13 1991-08-13 Yale University 2'-O-(4-benzoyl)benzoyl nucleoside cyclic monophosphate
FR2685918B1 (fr) * 1992-01-08 1995-06-23 Union Pharma Scient Appl Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista

Also Published As

Publication number Publication date
CN1315862A (zh) 2001-10-03
EP1110554B1 (en) 2006-03-08
DE69930271T8 (de) 2006-12-28
AU5446299A (en) 2000-03-21
ATE319458T1 (de) 2006-03-15
DE69930271D1 (de) 2006-05-04
EP1110554A1 (en) 2001-06-27
CN1151794C (zh) 2004-06-02
CA2342204A1 (en) 2000-03-09
WO2000012098A1 (en) 2000-03-09
EP1110554A4 (en) 2002-02-06
US6387889B1 (en) 2002-05-14
JP2002173427A (ja) 2002-06-21
DE69930271T2 (de) 2006-08-24
ES2259842T3 (es) 2006-10-16

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