DK1115417T3 - Anvendelse af daptomycin - Google Patents

Anvendelse af daptomycin

Info

Publication number: DK1115417T3
Authority: DK; Denmark
Prior art keywords: daptomycin; administering; muscle toxicity; skeletal muscle; effective amount
Prior art date: 1998-09-25

Application number

DK99949913T

Other languages

Danish (da)

English (en)

Inventor

Frederick B Oleson Jr

Francis P Tally

Original Assignee

Cubist Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-25

Filing date

1999-09-24

Publication date

2006-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26798675&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1115417(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-09-24 Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc

2006-07-31 Application granted granted Critical

2006-07-31 Publication of DK1115417T3 publication Critical patent/DK1115417T3/da

Links

108010013198 Daptomycin Proteins 0.000 title abstract 6
DOAKLVKFURWEDJ-QCMAZARJSA-N daptomycin Chemical compound C([C@H]1C(=O)O[C@H](C)[C@@H](C(NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](C(=O)N1)[C@H](C)CC(O)=O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)CCCCCCCCC)C(=O)C1=CC=CC=C1N DOAKLVKFURWEDJ-QCMAZARJSA-N 0.000 title abstract 6
229960005484 daptomycin Drugs 0.000 title abstract 6
231100000483 muscle toxicity Toxicity 0.000 abstract 6
210000002027 skeletal muscle Anatomy 0.000 abstract 4
108010028921 Lipopeptides Proteins 0.000 abstract 2
PPKJUHVNTMYXOD-PZGPJMECSA-N c49ws9n75l Chemical compound O=C([C@@H]1N(C2=O)CC[C@H]1S(=O)(=O)CCN(CC)CC)O[C@H](C(C)C)[C@H](C)\C=C\C(=O)NC\C=C\C(\C)=C\[C@@H](O)CC(=O)CC1=NC2=CO1.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2C[C@@H](CS[C@H]3C4CCN(CC4)C3)C(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O PPKJUHVNTMYXOD-PZGPJMECSA-N 0.000 abstract 2
229940052337 quinupristin/dalfopristin Drugs 0.000 abstract 2
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DK99949913T 1998-09-25 1999-09-24 Anvendelse af daptomycin DK1115417T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10182898P	1998-09-25	1998-09-25
US12575099P	1999-03-24	1999-03-24

Publications (1)

Publication Number	Publication Date
DK1115417T3 true DK1115417T3 (da)	2006-07-31

Family

ID=26798675

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK99949913T DK1115417T3 (da)	1998-09-25	1999-09-24	Anvendelse af daptomycin
DK06006697.4T DK1674107T3 (en)	1998-09-25	1999-09-24	Use of daptomycin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK06006697.4T DK1674107T3 (en)	1998-09-25	1999-09-24	Use of daptomycin

Country Status (26)

Country	Link
US (2)	US6468967B1 (de)
EP (2)	EP1115417B1 (de)
JP (4)	JP4184607B2 (de)
KR (2)	KR20010075327A (de)
CN (2)	CN1530136A (de)
AT (1)	ATE322280T1 (de)
AU (1)	AU764348B2 (de)
BR (1)	BR9914051A (de)
CA (1)	CA2344318C (de)
CY (3)	CY1105556T1 (de)
DE (3)	DE122006000049I2 (de)
DK (2)	DK1115417T3 (de)
ES (2)	ES2603086T3 (de)
HK (1)	HK1040363B (de)
HU (1)	HU230656B1 (de)
IS (2)	IS5890A (de)
LU (1)	LU91254I2 (de)
NL (1)	NL300232I2 (de)
NO (1)	NO20011454L (de)
NZ (1)	NZ510690A (de)
PL (2)	PL203689B1 (de)
PT (2)	PT1674107T (de)
RU (1)	RU2363489C9 (de)
SI (2)	SI1115417T1 (de)
TR (1)	TR200100841T2 (de)
WO (1)	WO2000018419A2 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL203689B1 (pl)	1998-09-25	2009-11-30	Cubist Pharmaceuticals	Zastosowanie daptomycyny
CN1425025A (zh)	1999-12-15	2003-06-18	卡比斯特制药公司	作为抗菌剂的新颖的脂肽
US6696412B1 (en)	2000-01-20	2004-02-24	Cubist Pharmaceuticals, Inc.	High purity lipopeptides, Lipopeptide micelles and processes for preparing same
WO2002059145A1 (en) *	2000-12-18	2002-08-01	Cubist Pharmaceuticals, Inc.	Methods for preparing purified lipopeptides
US20060014674A1 (en)	2000-12-18	2006-01-19	Dennis Keith	Methods for preparing purified lipopeptides
IL156394A0 (en) *	2000-12-18	2004-01-04	Cubist Pharm Inc	Methods for preparing purified lipopeptides
EP1932853A1 (de)	2001-08-06	2008-06-18	Cubist Pharmaceutical Inc.	Neue Depsipeptide und Herstellungsverfahren dafür
WO2004017925A2 (en) *	2002-08-23	2004-03-04	Genome Therapeutics Corporation	Methods and reagents for preventing bacteremias
US20060074014A1 (en) *	2002-11-18	2006-04-06	Vicuron Pharmaceuticals Inc.	Dalbavancin compositions for treatment of bacterial infections
US20050277581A1 (en) *	2002-11-18	2005-12-15	Vicuron Pharmaceuticals Inc.	Dalbavancin compositions for treatment of bacterial infections
US20050220862A1 (en) *	2004-03-31	2005-10-06	Bernstein Joel E	Compositions with reduced hepatotoxicity
US20060004185A1 (en) *	2004-07-01	2006-01-05	Leese Richard A	Peptide antibiotics and peptide intermediates for their prepartion
US20060014677A1 (en) *	2004-07-19	2006-01-19	Isotechnika International Inc.	Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
US20080051326A1 (en) *	2004-11-12	2008-02-28	Alexander Dylan C	Antiinfective Lipopeptides
US8546423B2 (en)	2005-05-18	2013-10-01	Mpex Pharmaceuticals, Inc.	Aerosolized fluoroquinolones and uses thereof
US7838532B2 (en) *	2005-05-18	2010-11-23	Mpex Pharmaceuticals, Inc.	Aerosolized fluoroquinolones and uses thereof
US20070238630A1 (en) *	2006-03-29	2007-10-11	Phillips Douglas H	Subcutaneous skin cleanser
EP2018864A1 (de)	2007-07-23	2009-01-28	Biomet Deutschland GmbH	Pharmazeutische Zusammensetzung, Substrat mit einer pharmazeutischen Zusammensetzung und Verwendung einer pharmazeutischen Zusammensetzung
CA2713989A1 (en) *	2008-03-04	2009-09-11	Elan Pharma International Limited	Stable liquid formulations of anti-infective agents and adjusted anti-infective agent dosing regimens
US20110166068A1 (en)	2008-07-17	2011-07-07	Acorda Therapeutics, Inc.	Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure
DE102008046610A1 (de) *	2008-09-09	2010-03-11	Biomet Deutschland Gmbh	Verwendung einer pharmazeutischen Zusammensetzung zur lokalen Infektionstherapie sowie Medizinprodukt
KR101959873B1 (ko)	2008-10-07	2019-03-19	랩터 파마슈티컬스 인코포레이티드	약동학 개선을 위한 에어로졸 플루오로퀴놀론 제형
CA2739893C (en)	2008-10-07	2016-10-04	Mpex Pharmaceuticals, Inc.	Inhalation of levofloxacin for reducing lung inflammation
US8809263B2 (en) *	2008-10-24	2014-08-19	Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center	Anti-infective hydroxy-phenyl-benzoates and methods of use
BRPI0923567A2 (pt)	2008-12-22	2016-09-27	Cubist Pharm Inc	agentes antibactericidas novos para o tratamento de infecções gram positivas
TW201035111A (en)	2008-12-23	2010-10-01	Biosource Pharm Inc	Antibiotic compositions for the treatment of gram negative infections
US8450300B2 (en) *	2009-07-13	2013-05-28	Cempra Pharmaceuticals Inc.	Fusidic acid dosing regimens for treatment of bacterial infections
WO2011008193A1 (en) *	2009-07-13	2011-01-20	Cempra Pharmaceuticals Inc.	Fusidic acid dosing regimens for treatment of bacterial infections
WO2011029059A1 (en)	2009-09-04	2011-03-10	Mpex Pharmaceuticals, Inc.	Use of aerosolized levofloxacin for treating cystic fibrosis
RU2607526C2 (ru)	2009-11-23	2017-01-10	Кьюбист Фармасьютикалз ЭлЭлСи	Липопептидные композиции и родственные способы
US8247394B2 (en)	2010-06-02	2012-08-21	Cempra Pharmaceuticals Inc.	Methods of treating urethritis and related infections using fusidic acid
US8415307B1 (en)	2010-06-23	2013-04-09	Biosource Pharm, Inc.	Antibiotic compositions for the treatment of gram negative infections
US8461188B2 (en)	2011-10-20	2013-06-11	Trius Therapeutics, Inc.	Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use
TW201343645A (zh)	2012-03-30	2013-11-01	Cubist Pharm Inc	１，３，４－□二唑及１，３，４－噻二唑β－內醯胺酶抑制劑
US9655946B2 (en) *	2012-09-11	2017-05-23	Hospira Australia Pty Ltd.	Daptomycin formulations and uses thereof
CN103006562B (zh) *	2013-01-21	2014-09-17	西南大学	达托霉素醇质体制剂
KR102237887B1 (ko)	2013-03-15	2021-04-07	멜린타 서브시디어리 코프.	항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법
US10647746B2 (en)	2016-04-08	2020-05-12	Versitech Limited	Antibacterial cyclic lipopeptides
US11667674B2 (en)	2016-04-08	2023-06-06	Versitech Limited	Antibacterial cyclic lipopeptides
JP2019515007A (ja) *	2016-05-13	2019-06-06	スペロポテンシエーターインコーポレイテッドＳｐｅｒｏＰｏｔｅｎｔｉａｔｏｒ，Ｉｎｃ．	新規カチオン性ペプチドｓｐｒ７４１による、抗生物質活性の増強
CN114788814B (zh) *	2021-01-26	2023-10-13	浙江创新生物有限公司	一种高稳定性的注射用达托霉素组合物及其制备方法和其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE32333E (en)	1978-10-16	1987-01-20	Eli Lilly And Company	A-21978 Antibiotics and process for their production
USRE32455E (en)	1978-10-16	1987-07-07	Eli Lilly And Company	A-21978 antibiotics and process for their production
US4537717A (en)	1982-05-21	1985-08-27	Eli Lilly And Company	Derivatives of A-21978C cyclic peptides
US4524135A (en)	1982-05-21	1985-06-18	Eli Lilly And Company	A-21978C cyclic peptides
US4482487A (en)	1982-05-21	1984-11-13	Eli Lilly And Company	A-21978C cyclic peptides
USRE32310E (en)	1982-05-21	1986-12-16	Eli Lilly And Company	Derivatives of A-21978C cyclic peptides
USRE32311E (en)	1982-05-21	1986-12-16	Eli Lilly And Company	Derivatives of A-21978C cyclic peptides
US4885243A (en)	1984-10-09	1989-12-05	Eli Lilly And Company	Process for producing A-21978C derivatives
US4800157A (en)	1985-09-09	1989-01-24	Eli Lilly And Company	Process for producing the A-21978C antibiotics
ZA883887B (en)	1987-06-10	1990-02-28	Lilly Co Eli	Chromatographic purification process
US4874843A (en)	1987-12-03	1989-10-17	Eli Lilly And Company	Chromatographic purification process
IL93618A0 (en) *	1989-03-06	1990-12-23	Lilly Co Eli	Improved diluent formulation for daptomycin
FR2755857B1 (fr) *	1996-11-19	1998-12-24	Rhone Poulenc Rorer Sa	Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation
FR2772272B1 (fr) *	1997-12-16	2000-01-14	Rhone Poulenc Rorer Sa	Compositions pharmaceutiques a base de dalfopristine et de quinupristine et leur preparation
PL203689B1 (pl)	1998-09-25	2009-11-30	Cubist Pharmaceuticals	Zastosowanie daptomycyny
US9393093B2 (en)	2008-02-18	2016-07-19	Covidien Lp	Clip for implant deployment device

1999
- 1999-09-24 PL PL348328A patent/PL203689B1/pl unknown
- 1999-09-24 JP JP2000571937A patent/JP4184607B2/ja not_active Expired - Lifetime
- 1999-09-24 AU AU62687/99A patent/AU764348B2/en not_active Expired
- 1999-09-24 TR TR2001/00841T patent/TR200100841T2/xx unknown
- 1999-09-24 PT PT60066974T patent/PT1674107T/pt unknown
- 1999-09-24 HK HK02100152.2A patent/HK1040363B/en not_active IP Right Cessation
- 1999-09-24 DE DE200612000049 patent/DE122006000049I2/de active Active
- 1999-09-24 AT AT99949913T patent/ATE322280T1/de active
- 1999-09-24 DK DK99949913T patent/DK1115417T3/da active
- 1999-09-24 SI SI9930904T patent/SI1115417T1/sl unknown
- 1999-09-24 SI SI9931082A patent/SI1674107T1/sl unknown
- 1999-09-24 HU HU0103874A patent/HU230656B1/hu unknown
- 1999-09-24 PL PL384274A patent/PL206091B1/pl unknown
- 1999-09-24 DE DE1999630758 patent/DE122006000049I1/de active Pending
- 1999-09-24 DK DK06006697.4T patent/DK1674107T3/en active
- 1999-09-24 KR KR1020017003735A patent/KR20010075327A/ko not_active Ceased
- 1999-09-24 ES ES06006697.4T patent/ES2603086T3/es not_active Expired - Lifetime
- 1999-09-24 BR BR9914051-9A patent/BR9914051A/pt not_active Application Discontinuation
- 1999-09-24 EP EP99949913A patent/EP1115417B1/de not_active Revoked
- 1999-09-24 EP EP06006697.4A patent/EP1674107B8/de not_active Expired - Lifetime
- 1999-09-24 NZ NZ510690A patent/NZ510690A/xx not_active IP Right Cessation
- 1999-09-24 CN CNA200410031708XA patent/CN1530136A/zh active Pending
- 1999-09-24 PT PT99949913T patent/PT1115417E/pt unknown
- 1999-09-24 US US09/406,568 patent/US6468967B1/en not_active Expired - Lifetime
- 1999-09-24 KR KR1020107006807A patent/KR20100051735A/ko not_active Ceased
- 1999-09-24 CA CA002344318A patent/CA2344318C/en not_active Expired - Lifetime
- 1999-09-24 DE DE69930758T patent/DE69930758T2/de not_active Expired - Lifetime
- 1999-09-24 CN CNB998124982A patent/CN1150029C/zh not_active Ceased
- 1999-09-24 WO PCT/US1999/022366 patent/WO2000018419A2/en not_active Ceased
- 1999-09-24 ES ES99949913T patent/ES2259845T3/es not_active Expired - Lifetime
2001
- 2001-03-14 IS IS5890A patent/IS5890A/is unknown
- 2001-03-22 NO NO20011454A patent/NO20011454L/no not_active Application Discontinuation
2002
- 2002-02-20 US US10/082,544 patent/US6852689B2/en not_active Expired - Lifetime
2003
- 2003-05-27 JP JP2003149968A patent/JP2003321389A/ja not_active Withdrawn
2004
- 2004-03-04 RU RU2004106569/14A patent/RU2363489C9/ru active
- 2004-08-17 JP JP2004237765A patent/JP2004339238A/ja not_active Withdrawn
2006
- 2006-04-18 CY CY20061100536T patent/CY1105556T1/el unknown
- 2006-06-23 NL NL300232C patent/NL300232I2/nl unknown
- 2006-06-28 LU LU91254C patent/LU91254I2/fr unknown
- 2006-07-18 CY CY200600003C patent/CY2006003I2/el unknown
- 2006-09-22 JP JP2006258107A patent/JP2006335773A/ja not_active Withdrawn
2009
- 2009-03-10 IS IS8807A patent/IS8807A/is unknown
2016
- 2016-11-24 CY CY20161101219T patent/CY1118334T1/el unknown

Also Published As

Publication number	Publication date
CN1530136A (zh)	2004-09-22
PT1674107T (pt)	2016-12-07
CY2006003I1 (el)	2009-11-04
EP1674107B1 (de)	2016-08-24
EP1674107A2 (de)	2006-06-28
JP4184607B2 (ja)	2008-11-19
AU6268799A (en)	2000-04-17
NL300232I1 (nl)	2006-09-01
ES2603086T3 (es)	2017-02-23
SI1115417T1 (sl)	2006-08-31
NO20011454L (no)	2001-05-25
WO2000018419A3 (en)	2000-07-06
DK1674107T3 (en)	2016-12-19
RU2004106569A (ru)	2005-08-10
EP1115417B1 (de)	2006-04-05
EP1674107B8 (de)	2017-01-25
AU764348B2 (en)	2003-08-14
US6468967B1 (en)	2002-10-22
PL203689B1 (pl)	2009-11-30
SI1674107T1 (sl)	2017-01-31
EP1674107A3 (de)	2012-06-20
IS5890A (is)	2001-03-14
IS8807A (is)	2009-03-10
DE69930758D1 (de)	2006-05-18
JP2004339238A (ja)	2004-12-02
DE69930758T2 (de)	2007-04-26
WO2000018419A2 (en)	2000-04-06
US20020142948A1 (en)	2002-10-03
EP1674107A8 (de)	2006-10-04
DE122006000049I1 (de)	2007-01-04
PL206091B1 (pl)	2010-06-30
CA2344318A1 (en)	2000-04-06
HK1040363A1 (en)	2002-06-07
RU2363489C2 (ru)	2009-08-10
JP2003321389A (ja)	2003-11-11
BR9914051A (pt)	2001-06-19
KR20010075327A (ko)	2001-08-09
NL300232I2 (nl)	2007-01-02
CA2344318C (en)	2006-07-04
KR20100051735A (ko)	2010-05-17
NZ510690A (en)	2002-10-25
PT1115417E (pt)	2006-07-31
JP2002525335A (ja)	2002-08-13
CY1105556T1 (el)	2010-07-28
US6852689B2 (en)	2005-02-08
TR200100841T2 (tr)	2002-01-21
NO20011454D0 (no)	2001-03-22
HUP0103874A2 (hu)	2002-02-28
RU2363489C9 (ru)	2010-03-20
CN1150029C (zh)	2004-05-19
HK1040363B (en)	2007-01-26
HUP0103874A3 (en)	2002-09-30
CY1118334T1 (el)	2017-06-28
EP1115417A2 (de)	2001-07-18
CY2006003I2 (el)	2009-11-04
ES2259845T3 (es)	2006-10-16
HU230656B1 (hu)	2017-06-28
PL348328A1 (en)	2002-05-20
ATE322280T1 (de)	2006-04-15
CN1348382A (zh)	2002-05-08
LU91254I2 (fr)	2006-08-28
JP2006335773A (ja)	2006-12-14
DE122006000049I2 (de)	2007-11-08

Publication	Publication Date	Title
DK1115417T3 (da)	2006-07-31	Anvendelse af daptomycin
DK1346041T3 (da)	2007-07-02	Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
ATE260658T1 (de)	2004-03-15	Pharmazeutische zubereitungen zur verminderung von atmungsdepressionen
DK0583421T3 (da)	1999-11-22	Substituerede dibenzoxazepinforbindelser, lægemidler og fremgangsmåder til anvendelse
DK1201246T3 (da)	2009-02-23	Anvendelse af trombopoietin som et medikament til behandling og forebyggelse af trombocytopeni
ES2106531T3 (es)	1997-11-01	Compuestos de dibenzoxazepina substituidos en 2, 3, 4, 5, 6, 7, 8, 9 y/o 10, composiciones farmaceuticas y metodos de uso.
IL136733A0 (en)	2001-06-14	Pharmaceutical composition containing sibutramine and orlistat
GB2331926A (en)	1999-06-09	Pharmaceutical compositions containing ibuprofen and domperidone for the treatment of migraine
HUP0000110A2 (hu)	2000-06-28	Azaciklusos, azabiciklusos vagy tetrahidropiridinszármazékokat tartalmazó, fájdalom kezelésére alkalmas gyógyászati készítmények
BG106180A (en)	2002-08-30	Pharmaceutical composition containing sibutramine and orlistat
FI923662A0 (fi)	1992-08-14	Terapeutiska medel.
SE9803623D0 (sv)	1998-10-22	New therapeutic application