DK1201246T3 - Anvendelse af trombopoietin som et medikament til behandling og forebyggelse af trombocytopeni - Google Patents

Anvendelse af trombopoietin som et medikament til behandling og forebyggelse af trombocytopeni

Info

Publication number
DK1201246T3
DK1201246T3 DK01123002T DK01123002T DK1201246T3 DK 1201246 T3 DK1201246 T3 DK 1201246T3 DK 01123002 T DK01123002 T DK 01123002T DK 01123002 T DK01123002 T DK 01123002T DK 1201246 T3 DK1201246 T3 DK 1201246T3
Authority
DK
Denmark
Prior art keywords
thrombopoietin
thrombocytopenia
treatment
low
materials
Prior art date
Application number
DK01123002T
Other languages
English (en)
Inventor
Griffith R Thomas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1201246T3 publication Critical patent/DK1201246T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/524Thrombopoietin, i.e. C-MPL ligand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK01123002T 1996-01-25 1997-01-13 Anvendelse af trombopoietin som et medikament til behandling og forebyggelse af trombocytopeni DK1201246T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59192596A 1996-01-25 1996-01-25
US64144396A 1996-04-29 1996-04-29
US08/697,631 US5879673A (en) 1996-01-25 1996-08-28 Administration of thrombopoietin on a single day only
PCT/US1997/000438 WO1997026907A1 (en) 1996-01-25 1997-01-13 Novel administration of thrombopoietin

Publications (1)

Publication Number Publication Date
DK1201246T3 true DK1201246T3 (da) 2009-02-23

Family

ID=27416624

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97901434T DK0876152T3 (da) 1996-01-25 1997-01-13 Hidtil ukendt administrering af thrombopoietin
DK01123002T DK1201246T3 (da) 1996-01-25 1997-01-13 Anvendelse af trombopoietin som et medikament til behandling og forebyggelse af trombocytopeni

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK97901434T DK0876152T3 (da) 1996-01-25 1997-01-13 Hidtil ukendt administrering af thrombopoietin

Country Status (11)

Country Link
US (1) US5879673A (da)
EP (2) EP0876152B1 (da)
JP (1) JP2000504325A (da)
AT (2) ATE411039T1 (da)
AU (1) AU711639B2 (da)
CA (1) CA2242417A1 (da)
DE (2) DE69712036T2 (da)
DK (2) DK0876152T3 (da)
ES (2) ES2175333T3 (da)
PT (1) PT876152E (da)
WO (1) WO1997026907A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001501619A (ja) * 1996-10-04 2001-02-06 アムジェン インコーポレーテッド mplリガンドを含有する医薬組成物
AU2006201129B2 (en) * 1997-05-21 2008-03-13 Genentech, Inc. Novel administration of thrombopoietin
JP4562815B2 (ja) * 1997-05-21 2010-10-13 ジェネンテック, インコーポレイテッド トロンボポエチンの新規な投与
WO1999011262A1 (en) * 1997-09-02 1999-03-11 Roche Diagnostics Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia
US6776984B1 (en) 1999-08-20 2004-08-17 George R. Schwartz Induced regeneration and repair of damaged neurons and nerve axon myelin
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
US6871171B1 (en) * 2000-10-19 2005-03-22 Optimata Ltd. System and methods for optimized drug delivery and progression of diseased and normal cells
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
ES2370235T3 (es) * 2001-02-23 2011-12-13 Immunex Corporation Recuperación eficaz de proteínas replegadas correctamente.
DE10227606B3 (de) * 2002-06-20 2004-01-22 Bionethos Holding Gmbh Verwendung von Thrombopoietin zur Kultivierung von Hepatozyten
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
PL1636261T3 (pl) * 2003-06-26 2007-12-31 Merck Patent Gmbh Białka trombopoetynowe o ulepszonych właściwościach
AU2003271194A1 (en) * 2003-10-09 2005-04-21 Daewoong Co., Ltd. Process for purifying human thrombopoietin with high content of sialic acid
DK1699915T3 (da) 2003-12-30 2010-09-13 Augustinus Bader Anvendelse af erythropoietin til levervævsregenerering
US7879318B2 (en) * 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
US20150031623A1 (en) * 2011-09-29 2015-01-29 Mcw Research Foundation, Inc. Thrombopoietin receptor ligands for neuroprotection
CN102973922B (zh) * 2012-12-18 2016-02-03 华东理工大学 一种融合蛋白的应用
JP6050289B2 (ja) * 2013-07-11 2016-12-21 Jcrファーマ株式会社 組換え蛋白質高発現細胞株の選択法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT669929E (pt) * 1992-11-13 2007-04-30 Immunex Corp Ligando de elk, uma citoquina
US5578301A (en) * 1993-12-14 1996-11-26 Sandoz Ltd. Method for using GM-CSF to reduce the acute phase response in a patient being administered IL-6 therapy
SG47030A1 (en) * 1994-01-03 1998-03-20 Genentech Inc Thrombopoietin
DE69503849T2 (de) * 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5593666A (en) * 1994-08-16 1997-01-14 The University Of Tennessee Research Corp. Methods and compositions for treating thrombocytopenia
US6013067A (en) * 1995-06-07 2000-01-11 Zymogenetics, Inc. Methods for increasing hematopoietic cells

Also Published As

Publication number Publication date
WO1997026907A1 (en) 1997-07-31
AU1533597A (en) 1997-08-20
EP1201246B1 (en) 2008-10-15
JP2000504325A (ja) 2000-04-11
DE69712036T2 (de) 2002-11-28
AU711639B2 (en) 1999-10-21
CA2242417A1 (en) 1997-07-31
DE69739050D1 (de) 2008-11-27
EP0876152B1 (en) 2002-04-17
EP1201246A3 (en) 2002-05-08
ATE411039T1 (de) 2008-10-15
EP0876152A1 (en) 1998-11-11
US5879673A (en) 1999-03-09
EP1201246A2 (en) 2002-05-02
DK0876152T3 (da) 2002-08-12
ES2315255T3 (es) 2009-04-01
ES2175333T3 (es) 2002-11-16
ATE216257T1 (de) 2002-05-15
PT876152E (pt) 2002-09-30
DE69712036D1 (de) 2002-05-23

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