DK1121928T3 - Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider - Google Patents

Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider

Info

Publication number: DK1121928T3
Authority: DK; Denmark
Prior art keywords: esters; mixture; ester; acid; cholesterol
Prior art date: 2000-01-31

Application number

DK01300793T

Other languages

English (en)

Inventor

Endre Markovits Schersl

Original Assignee

Haerting S A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-31

Filing date

2001-01-30

Publication date

2008-03-17

2001-01-30 Application filed by Haerting S A filed Critical Haerting S A

2008-03-17 Application granted granted Critical

2008-03-17 Publication of DK1121928T3 publication Critical patent/DK1121928T3/da

Links

239000000203 mixture Substances 0.000 title abstract 20
239000008280 blood Substances 0.000 title abstract 7
210000004369 blood Anatomy 0.000 title abstract 7
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical class CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 title abstract 6
235000014113 dietary fatty acids Nutrition 0.000 title abstract 5
229930195729 fatty acid Natural products 0.000 title abstract 5
239000000194 fatty acid Substances 0.000 title abstract 5
150000004665 fatty acids Chemical class 0.000 title abstract 5
150000003626 triacylglycerols Chemical class 0.000 title abstract 5
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
150000002148 esters Chemical class 0.000 abstract 25
241000124008 Mammalia Species 0.000 abstract 9
238000008214 LDL Cholesterol Methods 0.000 abstract 6
108010028554 LDL Cholesterol Proteins 0.000 abstract 6
230000003028 elevating effect Effects 0.000 abstract 6
229940068065 phytosterols Drugs 0.000 abstract 6
108010023302 HDL Cholesterol Proteins 0.000 abstract 5
229960001109 policosanol Drugs 0.000 abstract 5
239000002253 acid Substances 0.000 abstract 4
YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 4
238000000034 method Methods 0.000 abstract 3
YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 abstract 2
OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 abstract 2
235000021294 Docosapentaenoic acid Nutrition 0.000 abstract 2
JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 2
DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 abstract 2
235000020661 alpha-linolenic acid Nutrition 0.000 abstract 2
235000021342 arachidonic acid Nutrition 0.000 abstract 2
229940114079 arachidonic acid Drugs 0.000 abstract 2
229960005135 eicosapentaenoic acid Drugs 0.000 abstract 2
JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 2
235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 2
229960004488 linolenic acid Drugs 0.000 abstract 2
KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 abstract 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Steroid Compounds (AREA)

DK01300793T 2000-01-31 2001-01-30 Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider DK1121928T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CL2000000209		2000-01-31

Publications (1)

Publication Number	Publication Date
DK1121928T3 true DK1121928T3 (da)	2008-03-17

Family

ID=38871703

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01300793T DK1121928T3 (da)	2000-01-31	2001-01-30	Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider

Country Status (6)

Country	Link
US (1)	US20020016314A1 (da)
EP (1)	EP1121928B1 (da)
AT (1)	ATE384518T1 (da)
DE (1)	DE60132508T2 (da)
DK (1)	DK1121928T3 (da)
ES (1)	ES2298197T3 (da)

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US6998501B1 (en) *	1999-08-30	2006-02-14	Ocean Nutrition Canada Limited	Nutritional supplement for lowering serum triglyceride and cholesterol levels
CA2382262C (en) *	1999-08-30	2004-12-07	Ocean Nutrition Canada Ltd.	A nutritional supplement for lowering serum triglyceride and cholesterol levels
FI20012553A0 (fi)	2001-12-21	2001-12-21	Raisio Benecol Oy	Syötävät koostumukset
IL147942A0 (en) *	2002-01-31	2002-08-14	Enzymotec Ltd	Method of fractionation of phytosterol esters in oil and products obtained thereby
US7214394B2 (en) *	2002-05-31	2007-05-08	Archer-Daniels-Midland Company	Policosanol compositions, extraction from novel sources, and uses thereof
AU2003240187A1 (en) *	2002-06-17	2003-12-31	Medestea Research And Production S.R.L.	A process for preparing long chain saturated or unsaturated oxygenated compounds
ES2209658B1 (es) *	2002-12-05	2005-10-01	Proyecto Empresarial Brudy, S.L.	Utilizacion del acido docosahexaenoico como principio activo para el tratamiento de la lipodistrofia.
DE10261061A1 (de) *	2002-12-24	2004-07-15	Nutrinova Nutrition Specialties & Food Ingredients Gmbh	Diätetisches Lebensmittel zur positiven Beeinflussung der kardiovaskulären Gesundheit
US20060233863A1 (en) *	2003-02-10	2006-10-19	Enzymotec Ltd.	Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
WO2005023832A1 (en) *	2003-09-05	2005-03-17	University Of Nebraska-Lincoln	Compound and method for enhancing the cholesterol lowering property of plant sterol and stanol esters
US20080182801A1 (en) *	2003-12-22	2008-07-31	Btg International Limited	Core 2 glcnac-t inhibitors
GB0329667D0 (en) *	2003-12-22	2004-01-28	King S College London	Core 2 GlcNAc-T inhibitor
GB0513881D0 (en)	2005-07-06	2005-08-10	Btg Int Ltd	Core 2 GLCNAC-T Inhibitors III
US20050163872A1 (en) *	2004-01-23	2005-07-28	Cargill, Incorporated	Compositions and methods for reducing cholesterol
US20050281932A1 (en) *	2004-06-18	2005-12-22	Good Humor - Breyers Ice Cream	Frozen confection
US20060009486A1 (en) *	2004-07-07	2006-01-12	Gm Pharmaceuticals Inc.	Composition and method for treatment and prevention of coronary artery disease
US7615641B2 (en) *	2004-07-20	2009-11-10	Sino Pharmaceuticals Corporation	Long chain aliphatic alcohol derivatives and methods of making and using same
US20060020031A1 (en) *	2004-07-26	2006-01-26	Roger Berlin	Compositions containing policosanol and omega-3 fatty acids and their pharmaceutical uses
US20060025486A1 (en) *	2004-07-27	2006-02-02	Roger Berlin	Compositions containing policosanol and B vitamins and their pharmaceutical uses
US20060024383A1 (en) *	2004-07-27	2006-02-02	Roger Berlin	Compositions containing policosanol and chromium and/or chromium salts and their pharmaceutical uses
US20090232916A1 (en) *	2004-08-09	2009-09-17	Avidor Shulman	Food products for diabetics
AU2005270831B2 (en)	2004-08-10	2011-08-25	Enzymotec Ltd.	Mixture of phytosterol ester(s) and 1, 3-diglyceride(s) for use in the treatment of medical conditions
GB0512726D0 (en) *	2005-06-22	2005-07-27	Btg Int Ltd	Multiple sclerosis therapy and diagnosis
GB0513888D0 (en) *	2005-07-06	2005-08-10	Btg Int Ltd	Core 2 GLCNAC-T Inhibitors II
US20070020340A1 (en) *	2005-07-25	2007-01-25	David Rubin	Fish oil products for reducing cholesterol, low density lipoprotein, and hypertension
US7678399B2 (en)	2005-12-05	2010-03-16	Bunge Oils, Inc.	Phytosterol containing deep-fried foods and methods with health promoting characteristics
US8202541B2 (en) *	2006-02-07	2012-06-19	U.S. Nutraceuticals, LLC	Dietary supplement composition for blood lipid health
US8017153B2 (en) *	2006-02-07	2011-09-13	U.S. Nutraceuticals, LLC	Dietary supplement composition for blood lipid health
JP2010509204A (ja) *	2006-11-03	2010-03-25	プロノヴァバイオファーマノルゲアーエス	脂肪酸アルコール
US8394425B2 (en) *	2007-04-05	2013-03-12	Pmc Formulas, Inc.	Methods for promoting cellular health and treatment of cancer
US7794758B2 (en) *	2007-04-05	2010-09-14	Pmc Formulas, Inc.	Compounds and methods for promoting cellular health and treatment of cancer
ES2334313B1 (es) *	2008-05-16	2011-01-24	Universidad Autonoma De Madrid	Procedimiento supercritico y enzimatico para obtener nuevos esteres de esteroles.
WO2012148929A2 (en)	2011-04-26	2012-11-01	Retrotope, Inc.	Disorders implicating pufa oxidation
KR101294970B1 (ko) *	2011-06-30	2013-08-09	고려대학교 산학협력단	폴리코사놀 에스터, 이의 제조 방법 및 이를 포함하는 첨가제

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US3031376A (en) *	1956-10-11	1962-04-24	Levin	Compositions comprising octacosanol, triacontanol, tetracosanol, or hexacosanol, andmethods employing same
JPS6299323A (ja) *	1985-10-25	1987-05-08	Yoshihide Hagiwara	高脂血症剤
JPS62224258A (ja) *	1986-03-25	1987-10-02	Jun Kawai	栄養食品
GB8819110D0 (en) *	1988-08-11	1988-09-14	Norsk Hydro As	Antihypertensive drug & method for production
EP0594612B2 (en) *	1991-05-03	2010-02-24	Raisio Nutrition Ltd.	Process for the preparation of a substance comprising a beta-sitostanol fatty acid ester or a mixture thereof
GB9300125D0 (en) *	1993-01-06	1993-03-03	Scotia Holdings Plc	Compositions containing esters of unsaturated fatty acids
ATE399004T1 (de) *	1993-12-13	2008-07-15	Avanir Pharmaceuticals	Formulierungen aus c-20 bis c-28 alkoholen und saccharoseestern
FI107015B (fi) *	1996-08-09	2001-05-31	Raisio Benecol Oy	Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike
US5952393A (en) *	1998-02-12	1999-09-14	Sorkin, Jr.; Harlan Lee	Composition for reducing serum cholesterol levels
EP1169462B1 (en) *	1999-04-12	2009-10-21	Monsanto Technology LLC	Oil comprising brassicastanol

2001
- 2001-01-30 DK DK01300793T patent/DK1121928T3/da active
- 2001-01-30 DE DE60132508T patent/DE60132508T2/de not_active Expired - Lifetime
- 2001-01-30 AT AT01300793T patent/ATE384518T1/de active
- 2001-01-30 US US09/772,790 patent/US20020016314A1/en not_active Abandoned
- 2001-01-30 ES ES01300793T patent/ES2298197T3/es not_active Expired - Lifetime
- 2001-01-30 EP EP01300793A patent/EP1121928B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1121928A1 (en)	2001-08-08
US20020016314A1 (en)	2002-02-07
EP1121928B1 (en)	2008-01-23
DE60132508T2 (de)	2008-04-30
ES2298197T3 (es)	2008-05-16
ATE384518T1 (de)	2008-02-15
DE60132508D1 (de)	2008-03-13

Publication	Publication Date	Title
ATE384518T1 (de)	2008-02-15	Zusammensetzungen enthaltend phytosterol- und policosanolester von fettsäuren zur herabsetzung des cholesterol- und triglyceridspiegels
NZ608755A (en)	2014-11-28	Plant support formulation, vehicle for the delivery and translocation of phytologically beneficial substances and compositions containing same
WO2008027991A3 (en)	2008-06-19	USE OF DPA(n-6) OILS IN INFANT FORMULA
DE60023710D1 (de)	2005-12-08	Einphaseverfahren zur herstellung von fettsäuremethylestern aus gemischen von triglyceriden und fettsäuren
DK1152755T3 (da)	2002-07-22	Essentielle fedtsyrer til forebyggelse af cardiovaskulære tilfælde
DK1138326T3 (da)	2003-10-13	Anvendelse af syntetiske triglycerider på basis af konjugeret linolsyre til fremstilling af midler til støtte for kataboliske tilstande
ATE535509T1 (de)	2011-12-15	Verfahren zur herstellung von fettsäurealkylestern und acrolein aus triglyceriden
ATE279209T1 (de)	2004-10-15	Injizierbare pharmazeutische zusammensetzung zur systemischen verabreichung pharmakologisch aktiver wirkstoffe enthaltend mittelkettige triglyceride
DK0754186T3 (da)	1999-11-22	Fremgangsmåde til fremstilling af polyolpolyestere med lave niveauer af triglycerider
DK0682006T3 (da)	1999-10-18	Fremgangsmåde til fremstilling af et koncentrat af estere af flerumættede fede syrer
UY26303A1 (es)	2001-03-16	Composiciones farmacéuticas para administración oral y tópica
DE69328618D1 (de)	2000-06-15	Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung.
DK1476171T3 (da)	2011-01-10	Transport af nukleinsyresubstanser
ATE384073T1 (de)	2008-02-15	Verfahren zur gewinnung von sterinen aus fettsäurehaltigen rückständen
WO2002083058A3 (en)	2004-02-26	Anti-inflammatory fatty alcohols and fatty acid esters useful as antigen carriers
JPS63273485A (ja)	1988-11-10	油脂組成物の製法
DK1177729T3 (da)	2008-03-17	Farmaceutiske sammensætninger og levnedsmiddelsammensætninger med "træalkoholer" og "træsteroler" egnet til nedsættelse af serumcholesterol
MXPA01007680A (es)	2003-06-24	Procedimiento para obtener un aceite que es enriquecido en acidos grasos hidroxioctadecadienoicos (hode) o esteres de los mismos a partir de una mezcla oleosa que contiene acido linoleico o esteres del mismo.
JP4079516B2 (ja)	2008-04-23	トリグリセリドの製造方法
WO2004108871A3 (fr)	2005-02-17	Compositions liquides a base d'huile de colza oleique modifiee, utiles a titre de liquides isolants et caloporteurs, et dispositifs electriques les contenant
NO20031225D0 (no)	2003-03-17	Fremgangsmåte for fremstilling av råstoffer for utvinning av konjugert linolsyre
ATE531389T1 (de)	2011-11-15	Lipid- und distickstoffoxidverbindung als hilfsmittel zur erhöhung der impfstoffeffizienz
KR101583407B1 (ko)	2016-01-12	잣기름 지방산으로부터 농축된 피놀렌산을 회수하는 방법
KR102865475B1 (ko)	2025-09-25	저온결정법과 에스테르 반응을 이용한 오메가３ 불포화지방산의 효율적인 농축방법
JP2008127399A (ja)	2008-06-05	油脂の固液分離防止剤