DK1128829T3 - Kombination af riluzol og alfa-tocopherol - Google Patents

Kombination af riluzol og alfa-tocopherol

Info

Publication number: DK1128829T3
Authority: DK; Denmark
Prior art keywords: combination; riluzole; tocopherol; alpha; benzothiazole
Prior art date: 1998-11-13

Application number

DK99972101T

Other languages

English (en)

Inventor

Michel Dib

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-13

Filing date

1999-11-09

Publication date

2005-08-29

1999-11-09 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-08-29 Application granted granted Critical

2005-08-29 Publication of DK1128829T3 publication Critical patent/DK1128829T3/da

Links

GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 4
FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 3
229940087168 alpha tocopherol Drugs 0.000 title abstract 2
229960004181 riluzole Drugs 0.000 title abstract 2
229960000984 tocofersolan Drugs 0.000 title abstract 2
239000002076 α-tocopherol Substances 0.000 title abstract 2
235000004835 α-tocopherol Nutrition 0.000 title abstract 2
239000002671 adjuvant Substances 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Fats And Perfumes (AREA)
External Artificial Organs (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Cosmetics (AREA)
Pyrane Compounds (AREA)

DK99972101T 1998-11-13 1999-11-09 Kombination af riluzol og alfa-tocopherol DK1128829T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9814250A FR2785808B1 (fr)	1998-11-13	1998-11-13	Association riluzole et alpha-tocopherol
PCT/FR1999/002753 WO2000028992A1 (fr)	1998-11-13	1999-11-09	Association riluzole et alpha-tocopherol

Publications (1)

Publication Number	Publication Date
DK1128829T3 true DK1128829T3 (da)	2005-08-29

Family

ID=9532674

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99972101T DK1128829T3 (da)	1998-11-13	1999-11-09	Kombination af riluzol og alfa-tocopherol

Country Status (23)

Country	Link
US (2)	US6642262B2 (da)
EP (1)	EP1128829B1 (da)
JP (1)	JP4693241B2 (da)
KR (1)	KR100641472B1 (da)
CN (1)	CN1177587C (da)
AT (1)	ATE295168T1 (da)
AU (1)	AU776242B2 (da)
BR (1)	BR9915292A (da)
CA (1)	CA2350671C (da)
CZ (1)	CZ298808B6 (da)
DE (1)	DE69925301T2 (da)
DK (1)	DK1128829T3 (da)
EA (1)	EA003671B1 (da)
ES (1)	ES2239858T3 (da)
FR (1)	FR2785808B1 (da)
HK (1)	HK1041220B (da)
HU (1)	HU226067B1 (da)
IL (1)	IL142708A0 (da)
NO (1)	NO328349B1 (da)
PT (1)	PT1128829E (da)
TR (1)	TR200101346T2 (da)
WO (1)	WO2000028992A1 (da)
ZA (1)	ZA200103810B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2786101B1 (fr) *	1998-11-24	2002-07-05	Aventis Laboratoire	Utilisation de la nicergoline dans le traitement de la spasticite
CA2625341A1 (en) *	2005-10-18	2007-04-26	Ono Pharmaceutical Co., Ltd.	Pharmaceutical for protection of motor nerve in patient with amyotrophic lateral sclerosis
US20070099156A1 (en) *	2005-10-28	2007-05-03	Jeff Wagner	Self-etching dental primer compositions and methods and systems utilizing such compositions
FR2957077B1 (fr)	2010-03-02	2012-04-13	Univ Dauvergne Clermont I	Utilisation du riluzole pour traiter ou prevenir les effets indesirables d'agents anti-cancereux
WO2014145776A2 (en) *	2013-03-15	2014-09-18	Baylor College Of Medicine	Msp and its receptors in the therapy of amyotrophic lateral sclerosis
CN114344297B (zh) *	2022-03-01	2024-05-14	暨南大学	利鲁唑在治疗少精症中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2688138B1 (fr) *	1992-03-06	1995-05-05	Rhone Poulenc Rorer Sa	Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
US5843641A (en) *	1993-02-26	1998-12-01	Massachusetts Institute Of Technology	Methods for the daignosis, of familial amyotrophic lateral sclerosis
US6380252B1 (en) *	1996-07-05	2002-04-30	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1
US5780489A (en) *	1996-08-21	1998-07-14	Brooks; Benjamin Rix	Method for treating amyotrophic lateral sclerosis
JP3889844B2 (ja) *	1997-02-10	2007-03-07	龍兒梶	筋萎縮性側索硬化症治療剤
FR2782008B1 (fr) *	1998-08-07	2003-04-25	Sod Conseils Rech Applic	Utilisation d'extraits de ginkgo biloba pour preparer un medicament destine a traiter la sclerose laterale amyotrophique

1998
- 1998-11-13 FR FR9814250A patent/FR2785808B1/fr not_active Expired - Fee Related
1999
- 1999-11-09 KR KR1020017005912A patent/KR100641472B1/ko not_active Expired - Fee Related
- 1999-11-09 EA EA200100530A patent/EA003671B1/ru not_active IP Right Cessation
- 1999-11-09 CN CNB998131903A patent/CN1177587C/zh not_active Expired - Fee Related
- 1999-11-09 AT AT99972101T patent/ATE295168T1/de active
- 1999-11-09 BR BR9915292-4A patent/BR9915292A/pt not_active Application Discontinuation
- 1999-11-09 TR TR2001/01346T patent/TR200101346T2/xx unknown
- 1999-11-09 HU HU0105301A patent/HU226067B1/hu not_active IP Right Cessation
- 1999-11-09 CA CA2350671A patent/CA2350671C/fr not_active Expired - Fee Related
- 1999-11-09 ES ES99972101T patent/ES2239858T3/es not_active Expired - Lifetime
- 1999-11-09 WO PCT/FR1999/002753 patent/WO2000028992A1/fr not_active Ceased
- 1999-11-09 PT PT99972101T patent/PT1128829E/pt unknown
- 1999-11-09 EP EP99972101A patent/EP1128829B1/fr not_active Expired - Lifetime
- 1999-11-09 HK HK02102998.6A patent/HK1041220B/zh not_active IP Right Cessation
- 1999-11-09 JP JP2000582039A patent/JP4693241B2/ja not_active Expired - Fee Related
- 1999-11-09 DE DE69925301T patent/DE69925301T2/de not_active Expired - Lifetime
- 1999-11-09 CZ CZ20011561A patent/CZ298808B6/cs not_active IP Right Cessation
- 1999-11-09 DK DK99972101T patent/DK1128829T3/da active
- 1999-11-09 IL IL14270899A patent/IL142708A0/xx not_active IP Right Cessation
- 1999-11-09 AU AU11655/00A patent/AU776242B2/en not_active Ceased
2001
- 2001-05-10 ZA ZA200103810A patent/ZA200103810B/en unknown
- 2001-05-10 NO NO20012308A patent/NO328349B1/no not_active IP Right Cessation
- 2001-05-11 US US09/854,318 patent/US6642262B2/en not_active Expired - Lifetime
2003
- 2003-02-18 US US10/369,151 patent/US20030125363A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2350671A1 (fr)	2000-05-25
US6642262B2 (en)	2003-11-04
AU1165500A (en)	2000-06-05
PT1128829E (pt)	2005-07-29
CA2350671C (fr)	2010-05-04
ZA200103810B (en)	2002-08-12
HUP0105301A3 (en)	2006-07-28
TR200101346T2 (tr)	2002-05-21
DE69925301T2 (de)	2006-01-26
NO328349B1 (no)	2010-02-01
CZ20011561A3 (cs)	2001-08-15
HU226067B1 (en)	2008-04-28
NO20012308L (no)	2001-05-10
US20030125363A1 (en)	2003-07-03
HK1041220A1 (en)	2002-07-05
HK1041220B (zh)	2005-07-22
AU776242B2 (en)	2004-09-02
CN1326348A (zh)	2001-12-12
DE69925301D1 (de)	2005-06-16
FR2785808B1 (fr)	2002-12-06
EP1128829B1 (fr)	2005-05-11
US20020019426A1 (en)	2002-02-14
CN1177587C (zh)	2004-12-01
BR9915292A (pt)	2001-08-07
ATE295168T1 (de)	2005-05-15
HUP0105301A2 (hu)	2002-05-29
WO2000028992A1 (fr)	2000-05-25
JP4693241B2 (ja)	2011-06-01
EA003671B1 (ru)	2003-08-28
FR2785808A1 (fr)	2000-05-19
CZ298808B6 (cs)	2008-02-06
KR20010080407A (ko)	2001-08-22
JP2002529506A (ja)	2002-09-10
EA200100530A1 (ru)	2001-10-22
NO20012308D0 (no)	2001-05-10
ES2239858T3 (es)	2005-10-01
EP1128829A1 (fr)	2001-09-05
KR100641472B1 (ko)	2006-10-31
IL142708A0 (en)	2002-03-10

Publication	Publication Date	Title
DK1214936T3 (da)	2004-12-06	Anvendelse af thiazolidin- eller pyrrolidinderivater af aminosyrer som antihyperglykæmiske midler
DK0797439T3 (da)	2003-08-25	Anvendelse af pramipexol som et neurobeskyttende middel
DK1336605T3 (da)	2006-06-19	Substituerede phenolderivater eller salte deraf som inhibitorer af koagulationsfaktor X
FI962800A0 (fi)	1996-07-09	Fenyyliheterosyklisiä yhdisteitä COX-2 inhibiittoreina
DK1288206T3 (da)	2008-11-24	Substituerede benzensulfonamidderivater som prolægemidler af COX-2-inhibitorer
DK0923585T3 (da)	2002-07-01	Phosphinatbaserede inhibitorer af matrixmetalloproteinaser
DE69806067D1 (de)	2002-07-18	Bisulfatsalz eines hiv-protease-inhibitors
DK0464852T3 (da)	1996-04-15	2,6-Dialkyl-4-silyl-phenoler som antiatherosclerotiske midler og som antioxidanter
DE60121461D1 (de)	2006-08-24	Kondensierte pyridoindolderivate
FR2848116B1 (fr)	2007-01-05	Composition cosmetique comprenant un inhibiteur des metallo-proteinases et un lipopeptide.
NO20043107L (no)	2004-09-20	Bronnsementeringsbestanddeler for kalde omgivelser
DK1128829T3 (da)	2005-08-29	Kombination af riluzol og alfa-tocopherol
ATE211719T1 (de)	2002-01-15	Korrosionsinhibitoren enthaltender injektionszement
DE60121048D1 (de)	2006-08-03	PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
ATE315026T1 (de)	2006-02-15	Amlodipin-hemimaleat
UA26459C2 (uk)	1999-08-30	Іhгібітор впливу амілоїдhих білків
SV1998000088A (es)	2000-10-10	Compuestos farmaceuticos
ITRM910216A0 (it)	1991-04-02	Procedimento per la preparazione di composti amminici aromatici e relativo agente riducente. (caso 156-7123)
SE9303060L (sv)	1995-03-20	Löstagbar stoppanordning
ECSP982785A (es)	1999-05-17	Nuevos compuestos de tetrahidroizoquinoleinil- carboxamida, de formula (i) y procedimiento para su obtencion
ECSP972052A (es)	1998-02-13	Quinoxalinadionas
ID18481A (id)	1998-04-09	2-(3,5-difluorofenil)-3-(4-metilsulfonil)fenil)-2-siklopenten-1-on yang berguna sebagai inhibitor cox-2
SE9103040D0 (sv)	1991-10-18	Saekerhetsfodral
KR950019590U (ko)	1995-07-24	임의 위치고정이 가능한 축커플링
IT1303825B1 (it)	2001-02-23	Corredo di strumenti per microchirurgia oftalmica.