DK1137430T3 - Terapeutikum til undertrykkelse af snorkelyde - Google Patents

Terapeutikum til undertrykkelse af snorkelyde

Info

Publication number: DK1137430T3
Authority: DK; Denmark
Prior art keywords: bont; clostridium toxin; carrier; added; tent
Prior art date: 1998-12-10

Application number

DK99964547T

Other languages

English (en)

Inventor

Hans Bigalke

Juergen Frevert

Original Assignee

Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-10

Filing date

1999-12-10

Publication date

2003-06-16

1999-12-10 Application filed by Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh filed Critical Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh

2003-06-16 Application granted granted Critical

2003-06-16 Publication of DK1137430T3 publication Critical patent/DK1137430T3/da

Links

206010041235 Snoring Diseases 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
241000193403 Clostridium Species 0.000 abstract 6
239000003053 toxin Substances 0.000 abstract 6
231100000765 toxin Toxicity 0.000 abstract 6
108090000623 proteins and genes Proteins 0.000 abstract 3
102000004169 proteins and genes Human genes 0.000 abstract 3
101710117542 Botulinum neurotoxin type A Proteins 0.000 abstract 2
101710117524 Botulinum neurotoxin type B Proteins 0.000 abstract 2
101710117515 Botulinum neurotoxin type E Proteins 0.000 abstract 2
101710117520 Botulinum neurotoxin type F Proteins 0.000 abstract 2
101000933563 Clostridium botulinum Botulinum neurotoxin type G Proteins 0.000 abstract 2
101000985023 Clostridium botulinum C phage Botulinum neurotoxin type C Proteins 0.000 abstract 2
101000985020 Clostridium botulinum D phage Botulinum neurotoxin type D Proteins 0.000 abstract 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000185 hemagglutinin Substances 0.000 abstract 1
239000002502 liposome Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Orthopedics, Nursing, And Contraception (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)

DK99964547T 1998-12-10 1999-12-10 Terapeutikum til undertrykkelse af snorkelyde DK1137430T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19856897A DE19856897A1 (de)	1998-12-10	1998-12-10	Therapeutikum zur Unterdrückung von Schnarchgeräuschen
PCT/EP1999/009791 WO2000033863A2 (de)	1998-12-10	1999-12-10	Therapeutikum zur unterdrückung von schnarchgeräuschen

Publications (1)

Publication Number	Publication Date
DK1137430T3 true DK1137430T3 (da)	2003-06-16

Family

ID=7890562

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99964547T DK1137430T3 (da)	1998-12-10	1999-12-10	Terapeutikum til undertrykkelse af snorkelyde

Country Status (21)

Country	Link
US (1)	US6573241B1 (da)
EP (1)	EP1137430B1 (da)
JP (1)	JP4700811B2 (da)
KR (1)	KR100859556B1 (da)
CN (1)	CN1186095C (da)
AT (1)	ATE234108T1 (da)
AU (1)	AU764744B2 (da)
BR (1)	BR9915800A (da)
CA (1)	CA2353469A1 (da)
CZ (1)	CZ295769B6 (da)
DE (2)	DE19856897A1 (da)
DK (1)	DK1137430T3 (da)
ES (1)	ES2192880T3 (da)
HK (1)	HK1040636B (da)
HU (1)	HUP0104702A3 (da)
IL (2)	IL143528A0 (da)
NO (1)	NO328762B1 (da)
PL (1)	PL202908B1 (da)
PT (1)	PT1137430E (da)
RU (1)	RU2243783C2 (da)
WO (1)	WO2000033863A2 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19925739A1 (de) *	1999-06-07	2000-12-21	Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh	Therapeutikum mit einem Botulinum-Neurotoxin
US20080038274A1 (en)	1999-09-23	2008-02-14	Foster Keith A	Inhibition of secretion from non-neuronal cells
DE10035156A1 (de) *	2000-07-19	2002-02-07	Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh	Proteinkomplex als Vehikel für oral verfügbare Protein-Arzneimittel
US20100104631A1 (en) *	2001-08-13	2010-04-29	Lipella Pharmaceuticals Inc.	Method of treatment for bladder dysfunction
US7763663B2 (en) *	2001-12-19	2010-07-27	University Of Massachusetts	Polysaccharide-containing block copolymer particles and uses thereof
US7691394B2 (en) *	2002-05-28	2010-04-06	Botulinum Toxin Research Associates, Inc.	High-potency botulinum toxin formulations
US20040009180A1 (en) *	2002-07-11	2004-01-15	Allergan, Inc.	Transdermal botulinum toxin compositions
US7183066B2 (en) *	2002-09-27	2007-02-27	Allergan, Inc.	Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins
US20060057165A1 (en) *	2004-09-10	2006-03-16	Dimitrios Dimitrakoudis	Clostridium botulinum toxin formulation and method for reducing weight
WO2006138127A2 (en) *	2005-06-14	2006-12-28	Botulinum Toxin Research Associates, Inc.	Botulinum toxin and the treatment of primary disorders of mood and affect
US8926991B2 (en)	2005-06-14	2015-01-06	Botulinum Toxin Research Associates, Inc.	Botulinum toxin and the treatment of primary disorders of mood and affect
US20150258183A1 (en)	2006-06-07	2015-09-17	Botulinum Toxin Research Associates, Inc.	Botulinum Toxin and the Treatment of Primary Disorders of Mood and Affect
KR20130079645A (ko)	2005-07-18	2013-07-10	유니버시티 오브 메사츄세츠 로웰	나노에멀젼 조성물 및 이의 제조 및 사용 방법
US9486408B2 (en)	2005-12-01	2016-11-08	University Of Massachusetts Lowell	Botulinum nanoemulsions
CN101374498A (zh)	2005-12-01	2009-02-25	麻萨诸塞州洛厄尔大学	肉毒杆菌纳米乳液
US10792344B2 (en)	2006-06-29	2020-10-06	Merz Pharma Gmbh & Co. Kgaa	High frequency application of botulinum toxin therapy
AR061669A1 (es) *	2006-06-29	2008-09-10	Merz Pharma Gmbh & Co Kgaa	Aplicacion de alta frecuencia de terapia con toxina botulinica
SG10201607909WA (en) *	2006-12-01	2016-11-29	Anterios Inc	Peptide nanoparticles and uses therefor
WO2008070538A2 (en)	2006-12-01	2008-06-12	Anterios, Inc.	Micellar nanoparticles comprising botulinum toxin
CN101765423B (zh)	2007-05-31	2014-08-06	安特里奥公司	核酸纳米粒子和其用途
KR102080429B1 (ko) *	2008-06-26	2020-02-21	안테리오스, 인코퍼레이티드	경피 운반
EP2364168A1 (en)	2008-12-04	2011-09-14	Botulinum Toxin Research Associates, Inc.	Extended length botulinum toxin formulation for human or mammalian use
WO2010078403A2 (en) *	2008-12-30	2010-07-08	Lipella Pharmaceuticals Inc.	Methods and compositions for diagnosing urological disorders
JP2013510193A (ja) *	2009-11-09	2013-03-21	サンダース，イラ	神経毒を用いる睡眠呼吸障害の処置
HUE033172T2 (en)	2011-05-19	2017-11-28	Ipsen Bioinnovation Ltd	A method for producing proteolytically processed polypeptides
US9393291B2 (en)	2012-04-12	2016-07-19	Botulinum Toxin Research Associates, Inc.	Use of botulinum toxin for the treatment of cerebrovascular disease, renovascular and retinovascular circulatory beds
CN111454931A (zh)	2012-11-21	2020-07-28	益普生生物创新有限公司	用于制备经蛋白水解处理的多肽的方法
GB201407525D0 (en)	2014-04-29	2014-06-11	Syntaxin Ltd	Manufacture of recombinant clostridium botulinum neurotoxins
US11484580B2 (en)	2014-07-18	2022-11-01	Revance Therapeutics, Inc.	Topical ocular preparation of botulinum toxin for use in ocular surface disease
US9901627B2 (en)	2014-07-18	2018-02-27	Revance Therapeutics, Inc.	Topical ocular preparation of botulinum toxin for use in ocular surface disease
EP3541358A1 (en)	2016-11-21	2019-09-25	Eirion Therapeutics, Inc.	Transdermal delivery of large agents

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4551473A (en) *	1984-04-26	1985-11-05	Schossow George W	Method of inhibiting snoring and obstructive sleep apnea
WO1994000481A1 (en) *	1992-06-23	1994-01-06	Associated Synapse Biologics	Pharmaceutical composition containing botulinum b complex
RU2014016C1 (ru) *	1992-10-12	1994-06-15	Сергей Данилович Дорохов	Способ лечения храпа
US5365945A (en) *	1993-04-13	1994-11-22	Halstrom Leonard W	Adjustable dental applicance for treatment of snoring and obstructive sleep apnea
JP4249802B2 (ja)	1993-06-10	2009-04-08	アラーガン、インコーポレイテッド	神経筋疾患および症状を処置するためのボツリヌス毒素組み合わせ
US5570704A (en) *	1993-10-28	1996-11-05	Snoreless Corp	Universal, user-adjustable oral cavity appliance to control snoring and reduce episodes of obstructive sleep apnea
EP1488803B1 (en) *	1993-12-28	2008-03-26	Allergan, Inc.	Neurotoxic component of botulinum toxins for treating cervical dystonia
US5756468A (en) *	1994-10-13	1998-05-26	Wisconsin Alumni Research Foundation	Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation
US5512547A (en)	1994-10-13	1996-04-30	Wisconsin Alumni Research Foundation	Pharmaceutical composition of botulinum neurotoxin and method of preparation
RU2095079C1 (ru) *	1995-02-27	1997-11-10	Тамара Мироновна Авилова	Средство от храпа
SE9504537D0 (sv) *	1995-12-19	1995-12-19	Jan Hedner	Sätt att behandla och diagnosticera andningsstörningar under sömn och medel för utförande av sättet
US5721215A (en)	1996-03-20	1998-02-24	Allergan	Injectable therapy for control of muscle spasms and pain related to muscle spasms
US9316973B2 (en)	2013-06-13	2016-04-19	Lexmark International, Inc.	Heat transfer system for a fuser assembly

1998
- 1998-12-10 DE DE19856897A patent/DE19856897A1/de not_active Ceased
1999
- 1999-12-10 KR KR1020017006787A patent/KR100859556B1/ko not_active Expired - Fee Related
- 1999-12-10 PT PT99964547T patent/PT1137430E/pt unknown
- 1999-12-10 ES ES99964547T patent/ES2192880T3/es not_active Expired - Lifetime
- 1999-12-10 HU HU01047020104702A patent/HUP0104702A3/hu unknown
- 1999-12-10 DE DE59904569T patent/DE59904569D1/de not_active Expired - Lifetime
- 1999-12-10 US US09/857,835 patent/US6573241B1/en not_active Expired - Fee Related
- 1999-12-10 BR BR9915800-0A patent/BR9915800A/pt not_active IP Right Cessation
- 1999-12-10 CN CNB998139505A patent/CN1186095C/zh not_active Expired - Fee Related
- 1999-12-10 RU RU2001116080/14A patent/RU2243783C2/ru not_active IP Right Cessation
- 1999-12-10 AT AT99964547T patent/ATE234108T1/de active
- 1999-12-10 AU AU30374/00A patent/AU764744B2/en not_active Ceased
- 1999-12-10 CA CA002353469A patent/CA2353469A1/en not_active Abandoned
- 1999-12-10 WO PCT/EP1999/009791 patent/WO2000033863A2/de not_active Ceased
- 1999-12-10 EP EP99964547A patent/EP1137430B1/de not_active Expired - Lifetime
- 1999-12-10 CZ CZ20012058A patent/CZ295769B6/cs not_active IP Right Cessation
- 1999-12-10 DK DK99964547T patent/DK1137430T3/da active
- 1999-12-10 HK HK02102392.8A patent/HK1040636B/zh not_active IP Right Cessation
- 1999-12-10 IL IL14352899A patent/IL143528A0/xx active IP Right Grant
- 1999-12-10 JP JP2000586354A patent/JP4700811B2/ja not_active Expired - Fee Related
- 1999-12-10 PL PL349334A patent/PL202908B1/pl not_active IP Right Cessation
2001
- 2001-06-01 NO NO20012716A patent/NO328762B1/no not_active IP Right Cessation
- 2001-06-03 IL IL143528A patent/IL143528A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1040636A1 (en)	2002-06-21
IL143528A0 (en)	2002-04-21
IL143528A (en)	2008-04-13
JP2002531516A (ja)	2002-09-24
ATE234108T1 (de)	2003-03-15
AU3037400A (en)	2000-06-26
BR9915800A (pt)	2001-09-25
JP4700811B2 (ja)	2011-06-15
HUP0104702A2 (hu)	2002-04-29
PL349334A1 (en)	2002-07-15
WO2000033863A3 (de)	2000-11-02
CZ20012058A3 (cs)	2001-09-12
US6573241B1 (en)	2003-06-03
KR20010089527A (ko)	2001-10-06
NO20012716L (no)	2001-06-01
EP1137430B1 (de)	2003-03-12
CN1329501A (zh)	2002-01-02
RU2243783C2 (ru)	2005-01-10
HK1040636B (zh)	2003-05-30
PL202908B1 (pl)	2009-08-31
NO328762B1 (no)	2010-05-10
CN1186095C (zh)	2005-01-26
WO2000033863A2 (de)	2000-06-15
KR100859556B1 (ko)	2008-09-22
NO20012716D0 (no)	2001-06-01
DE59904569D1 (de)	2003-04-17
CA2353469A1 (en)	2000-06-15
AU764744B2 (en)	2003-08-28
PT1137430E (pt)	2003-07-31
DE19856897A1 (de)	2000-06-15
ES2192880T3 (es)	2003-10-16
CZ295769B6 (cs)	2005-11-16
HUP0104702A3 (en)	2003-09-29
EP1137430A2 (de)	2001-10-04

Publication	Publication Date	Title
ATE234108T1 (de)	2003-03-15	Therapeutikum zur unterdrückung von schnarchgeräuschen
WO2001034646A3 (en)	2001-12-06	Recombinant gelatins
ATE552891T1 (de)	2012-04-15	Kombination von sauren-proteaseenzymen und sauren pufferlösungen sowie deren verwendung
FR12C0004I2 (fr)	2013-01-11	Anticorps contre l'antigene ctla-4 humain et utilisation
BG100974A (en)	1998-04-30	Vaccines against papillomavirus
NO971889D0 (no)	1997-04-24	Forbindelser og sammensetninger for levering av aktive midler
WO2004110472A3 (en)	2005-02-03	Fusion proteins
ES2227527T3 (es)	2005-04-01	Un factor de crecimiento de queratinocitos (kgf) truncado que tiene actividad biologica aumentada.
IS4265A (is)	1995-08-19	Afleiður af mycophenolicsýrum, sem hafa efnahópa tengda-N-atómi í stöðu 6
DE69826684D1 (de)	2004-11-04	Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungen
RU2001116080A (ru)	2003-03-20	Терапевтический агент для подавления шумов храпа
WO2002038775A3 (en)	2004-02-26	METHODS FOR PRODUCING AND PURIFYING RECOMBINANT α-L-IDURONIDASE
WO2000018316A3 (en)	2000-11-16	Sustained release, and comfortable ophthalmic composition and method for ocular therapy
TR199900770T2 (xx)	1999-06-21	Nazal poliplerin tedavisinde bir H+, K+-ATPase'�n kullan�lmas�.
ATE272648T1 (de)	2004-08-15	Glycokonjugate von 20(s)-camptothecin
WO2002044384A3 (de)	2003-10-16	T-zellepitope des papillomavirus l1- und e7-proteins und ihre verwendung in diagnostik und therapie
DE69636527D1 (de)	2006-10-19	Antigenes protein aus malassezia
MXPA03007992A (es)	2004-09-29	Composicion farmaceutica de fragmentos f(ab)2 de anticuerpos y un proceso para su preparacion
AU7030700A (en)	2001-04-17	Preparation of highly pure toxin fragments
DE69635806D1 (de)	2006-04-20	Diphosphonat derivate von therapeutisch wirksamen stoffen
EA200000875A1 (ru)	2001-10-22	Белки, взаимодействующие с каспазой-8
AU6509898A (en)	1998-10-12	Activation of peptides
AU1875395A (en)	1995-09-04	4-amino derivatives of 5-substituted mycophenolic acid
ATE254469T1 (de)	2003-12-15	Verfahren zur verminderung der renalen aufnahme von antikörperfragmenten
ATE211489T1 (de)	2002-01-15	Chitosan enthaltende zusammensetzung