DK1140941T3 - Nitrogenholdige heterobicykliske forbindelser som faktor Xa-inhibitorer - Google Patents

Nitrogenholdige heterobicykliske forbindelser som faktor Xa-inhibitorer

Info

Publication number
DK1140941T3
DK1140941T3 DK99967444T DK99967444T DK1140941T3 DK 1140941 T3 DK1140941 T3 DK 1140941T3 DK 99967444 T DK99967444 T DK 99967444T DK 99967444 T DK99967444 T DK 99967444T DK 1140941 T3 DK1140941 T3 DK 1140941T3
Authority
DK
Denmark
Prior art keywords
inhibitors
nitrogen
factor
heterobicyclic compounds
containing heterobicyclic
Prior art date
Application number
DK99967444T
Other languages
English (en)
Inventor
John M Fevig
Joseph Cacciola
Charles G Clark
Patrick Yuk Sun Lam
James R Pruitt
Donald J P Pinto
Karen A Rossi
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1140941(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Application granted granted Critical
Publication of DK1140941T3 publication Critical patent/DK1140941T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK99967444T 1998-12-23 1999-12-17 Nitrogenholdige heterobicykliske forbindelser som faktor Xa-inhibitorer DK1140941T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11362898P 1998-12-23 1998-12-23
US12763399P 1999-04-02 1999-04-02
EP99967444A EP1140941B1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Publications (1)

Publication Number Publication Date
DK1140941T3 true DK1140941T3 (da) 2005-02-14

Family

ID=26811284

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99967444T DK1140941T3 (da) 1998-12-23 1999-12-17 Nitrogenholdige heterobicykliske forbindelser som faktor Xa-inhibitorer

Country Status (26)

Country Link
US (2) US6413980B1 (da)
EP (1) EP1140941B1 (da)
JP (1) JP2002533465A (da)
KR (1) KR100628407B1 (da)
CN (1) CN100340559C (da)
AR (1) AR024242A1 (da)
AT (1) ATE280171T1 (da)
AU (1) AU759711B2 (da)
BR (1) BR9917080A (da)
CA (1) CA2349330C (da)
DE (1) DE69921358T2 (da)
DK (1) DK1140941T3 (da)
EA (1) EA004515B1 (da)
ES (1) ES2232202T3 (da)
HK (1) HK1052508B (da)
HR (1) HRP990396A2 (da)
IL (2) IL142959A0 (da)
MX (1) MXPA01006502A (da)
MY (1) MY138239A (da)
NO (1) NO319816B1 (da)
NZ (1) NZ511674A (da)
PT (1) PT1140941E (da)
SI (1) SI1140941T1 (da)
TW (1) TWI225862B (da)
WO (1) WO2000039131A1 (da)
ZA (1) ZA200103795B (da)

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* Cited by examiner, † Cited by third party
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US6960595B2 (en) * 2001-03-23 2005-11-01 Bristol-Myers Squibb Pharma Company 5-6 to 5-7 Heterobicycles as factor Xa inhibitors
CA2441772A1 (en) 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1,4,5,6-tetrahydropyrazolo-¬3,4-c|-pyridin-7-ones as factor xa inhibitors
CA2444571A1 (en) * 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1, 4, 5, 6-tetrahydropyrazolo-¬3, 4-c|-pyridin-7-ones as factor xa inhi bitors
EP1414449A4 (en) * 2001-05-22 2005-04-06 Bristol Myers Squibb Co FACTOR XA BICYCLIC INHIBITORS
TWI331526B (en) 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
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Also Published As

Publication number Publication date
US20030004167A1 (en) 2003-01-02
JP2002533465A (ja) 2002-10-08
HRP990396A2 (en) 2000-08-31
ZA200103795B (en) 2002-08-12
SI1140941T1 (en) 2005-04-30
NO20013072L (no) 2001-06-20
IL142959A0 (en) 2002-04-21
WO2000039131A1 (en) 2000-07-06
CA2349330C (en) 2009-09-29
ATE280171T1 (de) 2004-11-15
AU2371700A (en) 2000-07-31
NO20013072D0 (no) 2001-06-20
BR9917080A (pt) 2002-03-12
DE69921358D1 (de) 2004-11-25
TWI225862B (en) 2005-01-01
MXPA01006502A (es) 2002-04-08
NO319816B1 (no) 2005-09-19
HK1052508B (zh) 2008-08-01
EA200100688A1 (ru) 2001-12-24
EP1140941B1 (en) 2004-10-20
US6673810B2 (en) 2004-01-06
IL142959A (en) 2010-05-31
EP1140941A1 (en) 2001-10-10
EA004515B1 (ru) 2004-04-29
MY138239A (en) 2009-05-29
CN1391575A (zh) 2003-01-15
CA2349330A1 (en) 2000-07-06
US6413980B1 (en) 2002-07-02
DE69921358T2 (de) 2006-03-09
ES2232202T3 (es) 2005-05-16
AR024242A1 (es) 2002-09-25
PT1140941E (pt) 2005-02-28
AU759711B2 (en) 2003-04-17
KR100628407B1 (ko) 2006-09-26
CN100340559C (zh) 2007-10-03
NZ511674A (en) 2003-11-28
HK1052508A1 (zh) 2003-09-19
KR20010092754A (ko) 2001-10-26

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