DK1155012T3 - Dihydroquinazolinderivater med anti-cancer-aktivitet - Google Patents

Dihydroquinazolinderivater med anti-cancer-aktivitet

Info

Publication number
DK1155012T3
DK1155012T3 DK00905212T DK00905212T DK1155012T3 DK 1155012 T3 DK1155012 T3 DK 1155012T3 DK 00905212 T DK00905212 T DK 00905212T DK 00905212 T DK00905212 T DK 00905212T DK 1155012 T3 DK1155012 T3 DK 1155012T3
Authority
DK
Denmark
Prior art keywords
cancer activity
dihydroquinazoline derivatives
dihydroquinazoline
derivatives
formulawhere
Prior art date
Application number
DK00905212T
Other languages
English (en)
Inventor
Lorraine Skelton
Vassilis Bavetsias
Ann Crc Jackman
Original Assignee
Cancer Rec Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Rec Tech Ltd filed Critical Cancer Rec Tech Ltd
Application granted granted Critical
Publication of DK1155012T3 publication Critical patent/DK1155012T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK00905212T 1999-02-24 2000-02-24 Dihydroquinazolinderivater med anti-cancer-aktivitet DK1155012T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904275.6A GB9904275D0 (en) 1999-02-24 1999-02-24 Anti-cancer compounds
PCT/GB2000/000655 WO2000050417A1 (en) 1999-02-24 2000-02-24 Anti-cancer dihydroquinazoline derivatives

Publications (1)

Publication Number Publication Date
DK1155012T3 true DK1155012T3 (da) 2004-08-09

Family

ID=10848434

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00905212T DK1155012T3 (da) 1999-02-24 2000-02-24 Dihydroquinazolinderivater med anti-cancer-aktivitet

Country Status (11)

Country Link
US (1) US6699861B1 (da)
EP (1) EP1155012B1 (da)
JP (1) JP2002537391A (da)
AT (1) ATE264322T1 (da)
AU (1) AU772670B2 (da)
CA (1) CA2364708A1 (da)
DE (1) DE60009868T2 (da)
DK (1) DK1155012T3 (da)
ES (1) ES2219308T3 (da)
GB (1) GB9904275D0 (da)
WO (1) WO2000050417A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2373644T3 (es) 2001-08-31 2012-02-07 Btg International Limited Uso de derivados de ciclopenta[g]quinazolina para el tratamiento del c�?ncer.
KR100983962B1 (ko) 2001-08-31 2010-09-27 비티지 인터내셔널 리미티드 항암제로서 사용되는 시클로펜타[ｇ]퀴나졸린 화합물
GB0121214D0 (en) 2001-08-31 2001-10-24 Btg Int Ltd Synthetic method
CA2459584A1 (en) * 2001-09-05 2003-03-13 Cynthia C. Bamdad Compositions and use thereof in the treatment of cancer
WO2007110868A2 (en) * 2006-03-28 2007-10-04 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
JP5732453B2 (ja) 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Ｎｈ酸性化合物のプロドラッグ
US8809526B2 (en) 2010-07-19 2014-08-19 Onyx Pharmaceuticals, Inc. Synthesis of cyclopentaquinazolines
CN106986856A (zh) 2010-09-03 2017-07-28 福马Tm有限责任公司 作为用于治疗疾病诸如癌症的nampt抑制剂的4‑{[(吡啶‑3‑基‑甲基)氨基羰基]氨基}苯‑砜衍生物
WO2012140642A1 (en) 2011-04-10 2012-10-18 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US9359367B2 (en) 2012-07-09 2016-06-07 Lupin Limited Tetrahydroquinazolinone derivatives as PARP inhibitors
AU2019230014B2 (en) 2018-03-05 2024-11-28 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0031237B1 (en) 1979-12-19 1984-10-17 National Research Development Corporation Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8607683D0 (en) 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
GB8809978D0 (en) 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
GB8829296D0 (en) 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
AU640016B2 (en) 1990-05-30 1993-08-12 Imperial Chemical Industries Plc Hydroquinazoline derivatives
GB9105771D0 (en) 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9220571D0 (en) 1992-09-30 1992-11-11 Ici Plc Quinazoline derivatives
GB9223352D0 (en) 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds

Also Published As

Publication number Publication date
DE60009868T2 (de) 2005-04-21
JP2002537391A (ja) 2002-11-05
EP1155012B1 (en) 2004-04-14
EP1155012A1 (en) 2001-11-21
CA2364708A1 (en) 2000-08-31
AU2683800A (en) 2000-09-14
WO2000050417A1 (en) 2000-08-31
GB9904275D0 (en) 1999-04-21
US6699861B1 (en) 2004-03-02
AU772670B2 (en) 2004-05-06
ES2219308T3 (es) 2004-12-01
ATE264322T1 (de) 2004-04-15
DE60009868D1 (en) 2004-05-19

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