ATE197401T1 - Chinazolinon-arzneimittel sowie deren verwendung - Google Patents

Chinazolinon-arzneimittel sowie deren verwendung

Info

Publication number
ATE197401T1
ATE197401T1 AT95933731T AT95933731T ATE197401T1 AT E197401 T1 ATE197401 T1 AT E197401T1 AT 95933731 T AT95933731 T AT 95933731T AT 95933731 T AT95933731 T AT 95933731T AT E197401 T1 ATE197401 T1 AT E197401T1
Authority
AT
Austria
Prior art keywords
group
hydrogen
quinazolinone
drugs
lower alkoxy
Prior art date
Application number
AT95933731T
Other languages
English (en)
Inventor
Arnon Nagler
Shimon Slavin
Israel Vlodavsky
Mark Pines
Original Assignee
Agricultural Res Org
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricultural Res Org, Hadasit Med Res Service filed Critical Agricultural Res Org
Application granted granted Critical
Publication of ATE197401T1 publication Critical patent/ATE197401T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT95933731T 1994-08-31 1995-08-29 Chinazolinon-arzneimittel sowie deren verwendung ATE197401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11083194A IL110831A (en) 1994-08-31 1994-08-31 Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis
PCT/US1995/011186 WO1996006616A1 (en) 1994-08-31 1995-08-29 Quinazolinone pharmaceuticals and use thereof

Publications (1)

Publication Number Publication Date
ATE197401T1 true ATE197401T1 (de) 2000-11-11

Family

ID=11066514

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95933731T ATE197401T1 (de) 1994-08-31 1995-08-29 Chinazolinon-arzneimittel sowie deren verwendung

Country Status (8)

Country Link
EP (1) EP0787000B1 (de)
JP (1) JPH10513149A (de)
CN (1) CN1108797C (de)
AT (1) ATE197401T1 (de)
AU (1) AU692307B2 (de)
DE (1) DE69519385T2 (de)
IL (1) IL110831A (de)
WO (1) WO1996006616A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114951A (en) * 1995-08-15 1999-08-17 Hadasit Med Res Service Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization
JP2001500040A (ja) * 1996-08-30 2001-01-09 イスラエル国 キナゾリノン誘導体を含有する冠状動脈内ステント
US6211188B1 (en) * 1997-02-11 2001-04-03 Hadasit Medical Research Services And Development Company Ltd Treatment of skin disorders
US6028075A (en) 1997-02-11 2000-02-22 Pines; Mark Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies
US6562829B1 (en) 1997-05-23 2003-05-13 Hadasit Medical Research Services & Development Co., Ltd. Treatment of hepatic cirrhosis
US6159488A (en) * 1997-08-14 2000-12-12 Agricultural Research Org. Ministry Of Agriculture (Gov.) Intracoronary stents containing quinazolinone derivatives
ATE307586T1 (de) * 1998-08-13 2005-11-15 Hadasit Med Res Service Hemmung von mit gewebetrauma verbundenen pathogenen prozessen
JP2002539262A (ja) * 1999-03-19 2002-11-19 パーカー ヒューズ インスティテュート キナゾリン化合物製剤および治療におけるその使用
US7064114B2 (en) 1999-03-19 2006-06-20 Parker Hughes Institute Gel-microemulsion formulations
EP1210086B1 (de) * 1999-09-09 2006-12-06 Hadasit Medical Research Services & Development Co., Ltd. Verwendung von halofuginone zur behandlung von urethralstriktur
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6753428B2 (en) 2001-11-20 2004-06-22 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
WO2003070701A2 (en) 2002-02-15 2003-08-28 Cytokinetics, Inc. Syntheses of quinazolinones
AU2003270015A1 (en) 2002-05-09 2003-12-02 Cytokinetics, Inc. Compounds, compositions, and methods
WO2003094839A2 (en) 2002-05-09 2003-11-20 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods
JP2005536475A (ja) 2002-05-23 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物、および方法
EP1556357A4 (de) 2002-06-14 2006-09-13 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren
EP1537089A4 (de) 2002-07-23 2008-04-16 Cytokinetics Inc Verbindungen, zusammenstellungen und verfahren
EP1558083A4 (de) 2002-09-30 2008-04-16 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren
JP2007513154A (ja) 2003-12-08 2007-05-24 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
KR20100024494A (ko) 2007-06-22 2010-03-05 아르퀼 인코포레이티드 퀴나졸리논 화합물 및 이의 사용 방법
CN114469956B (zh) * 2022-01-29 2023-07-18 中国科学技术大学 常山酮在治疗和预防动脉粥样硬化性疾病的药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US26833A (en) * 1860-01-17 Improvement in plows
US3320124A (en) * 1964-07-20 1967-05-16 American Cyanamid Co Method for treating coccidiosis with quinazolinones
DE2934069A1 (de) * 1979-08-23 1981-03-12 Hoechst Ag, 6000 Frankfurt Mittel gegen theileriosen und seine verwendung.
DE3703789A1 (de) * 1987-02-07 1988-08-18 Hoechst Ag Coccidiozide mittel
CA2113229C (en) * 1994-01-11 1999-04-20 Mark Pines Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof

Also Published As

Publication number Publication date
EP0787000A1 (de) 1997-08-06
JPH10513149A (ja) 1998-12-15
EP0787000B1 (de) 2000-11-08
AU3626895A (en) 1996-03-22
DE69519385D1 (de) 2000-12-14
WO1996006616A1 (en) 1996-03-07
CN1108797C (zh) 2003-05-21
IL110831A0 (en) 1994-11-11
CN1163566A (zh) 1997-10-29
AU692307B2 (en) 1998-06-04
IL110831A (en) 1998-12-27
DE69519385T2 (de) 2001-03-15
EP0787000A4 (de) 1997-11-12

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties