DK1155018T3 - Krystalmodifikation C af 8-cyano-1-cyclopropyl-7-(1S, 6S-2,8- diazabicyclo [4.3.0]nonan-8-yl) -6-fluor-1,4-dihydro-4-oxo-3-quinolin-carboxylsyre - Google Patents

Krystalmodifikation C af 8-cyano-1-cyclopropyl-7-(1S, 6S-2,8- diazabicyclo [4.3.0]nonan-8-yl) -6-fluor-1,4-dihydro-4-oxo-3-quinolin-carboxylsyre

Info

Publication number: DK1155018T3
Authority: DK; Denmark
Prior art keywords: nonan; diazabicyclo; cyclopropyl; dihydro; oxo
Prior art date: 1999-02-26

Application number

DK00909166T

Other languages

English (en)

Inventor

Hubert Rast

Thomas Himmler

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-26

Filing date

2000-02-14

Publication date

2003-02-17

2000-02-14 Application filed by Bayer Ag filed Critical Bayer Ag

2003-02-17 Application granted granted Critical

2003-02-17 Publication of DK1155018T3 publication Critical patent/DK1155018T3/da

Links

239000013078 crystal Substances 0.000 title abstract 4
230000004048 modification Effects 0.000 title abstract 4
238000012986 modification Methods 0.000 title abstract 4
-1 nonan-8-yl Chemical group 0.000 title 1
238000000034 method Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK00909166T 1999-02-26 2000-02-14 Krystalmodifikation C af 8-cyano-1-cyclopropyl-7-(1S, 6S-2,8- diazabicyclo [4.3.0]nonan-8-yl) -6-fluor-1,4-dihydro-4-oxo-3-quinolin-carboxylsyre DK1155018T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19908449A DE19908449A1 (de)	1999-02-26	1999-02-26	Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
PCT/EP2000/001202 WO2000052009A1 (de)	1999-02-26	2000-02-14	Kristallmodifikation c von 8-cyan-1- cyclopropyl -7- (1s, 6s-2,8- diazabicyclo [4.3.0] nonan -8-yl) -6-fluor -1,4- dihydro -4-oxo -3- chinolincarbon

Publications (1)

Publication Number	Publication Date
DK1155018T3 true DK1155018T3 (da)	2003-02-17

Family

ID=7899027

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00909166T DK1155018T3 (da)	1999-02-26	2000-02-14	Krystalmodifikation C af 8-cyano-1-cyclopropyl-7-(1S, 6S-2,8- diazabicyclo [4.3.0]nonan-8-yl) -6-fluor-1,4-dihydro-4-oxo-3-quinolin-carboxylsyre

Country Status (26)

Country	Link
US (1)	US6649762B1 (da)
EP (1)	EP1155018B1 (da)
JP (1)	JP2002538158A (da)
KR (1)	KR100756471B1 (da)
CN (1)	CN1191253C (da)
AT (1)	ATE226952T1 (da)
AU (1)	AU763003B2 (da)
BR (1)	BR0008493A (da)
CA (1)	CA2362801A1 (da)
CZ (1)	CZ299700B6 (da)
DE (2)	DE19908449A1 (da)
DK (1)	DK1155018T3 (da)
ES (1)	ES2181644T3 (da)
HK (1)	HK1044948B (da)
HU (1)	HUP0200006A3 (da)
IL (2)	IL144702A0 (da)
NO (1)	NO320191B1 (da)
NZ (1)	NZ513750A (da)
PL (1)	PL349368A1 (da)
PT (1)	PT1155018E (da)
RU (1)	RU2248356C2 (da)
SK (1)	SK285562B6 (da)
TR (1)	TR200102434T2 (da)
UA (1)	UA70356C2 (da)
WO (1)	WO2000052009A1 (da)
ZA (1)	ZA200106289B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19854356A1 (de)	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de)	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) *	1999-02-26	2000-08-31	Bayer Ag	Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de)	1999-02-26	2000-08-31	Bayer Ag	Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE102004015981A1 (de) *	2004-04-01	2005-10-20	Bayer Healthcare Ag	Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) *	2006-10-20	2008-04-24	Bayer Healthcare Ag	Verfahren zur Herstellung von Pradofloxacin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2676521B2 (ja)	1988-03-22	1997-11-17	北陸製薬株式会社	キノロンカルボン酸化合物ｉ型結晶の製造法
MX9703622A (es) *	1994-11-18	1997-08-30	Upjohn Co	Una nueva forma solida fisicamente estable en una fluoroquinolona.
DE19546249A1 (de)	1995-12-12	1997-06-19	Bayer Ag	Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) *	1996-02-23	1997-08-28	Bayer Ag	Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
BR9707606B1 (pt) *	1996-02-23	2010-08-10		ácidos 8-ciano-1-ciclopropil-7-(2,8-diazabiciclo(4.3.0) nonan-8-il)-6-flúor-1,4-diidro-4-oxo-3-quinolinocarbo xìlicos, bem como medicamentos que os compreendem.
DE19854356A1 (de)	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de)	1998-11-25	2000-05-31	Bayer Ag	Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) *	1999-02-26	2000-08-31	Bayer Ag	Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de)	1999-02-26	2000-08-31	Bayer Ag	Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure

1999
- 1999-02-26 DE DE19908449A patent/DE19908449A1/de not_active Withdrawn
2000
- 2000-02-14 CA CA002362801A patent/CA2362801A1/en not_active Abandoned
- 2000-02-14 RU RU2001126300/04A patent/RU2248356C2/ru not_active IP Right Cessation
- 2000-02-14 CN CNB008043558A patent/CN1191253C/zh not_active Expired - Fee Related
- 2000-02-14 DE DE50000700T patent/DE50000700D1/de not_active Expired - Fee Related
- 2000-02-14 JP JP2000602235A patent/JP2002538158A/ja not_active Withdrawn
- 2000-02-14 CZ CZ20013064A patent/CZ299700B6/cs not_active IP Right Cessation
- 2000-02-14 HK HK02106521.3A patent/HK1044948B/zh not_active IP Right Cessation
- 2000-02-14 TR TR2001/02434T patent/TR200102434T2/xx unknown
- 2000-02-14 IL IL14470200A patent/IL144702A0/xx active IP Right Grant
- 2000-02-14 NZ NZ513750A patent/NZ513750A/en unknown
- 2000-02-14 SK SK1195-2001A patent/SK285562B6/sk unknown
- 2000-02-14 US US09/914,090 patent/US6649762B1/en not_active Expired - Fee Related
- 2000-02-14 ES ES00909166T patent/ES2181644T3/es not_active Expired - Lifetime
- 2000-02-14 EP EP00909166A patent/EP1155018B1/de not_active Expired - Lifetime
- 2000-02-14 KR KR1020017009811A patent/KR100756471B1/ko not_active Expired - Fee Related
- 2000-02-14 AT AT00909166T patent/ATE226952T1/de not_active IP Right Cessation
- 2000-02-14 WO PCT/EP2000/001202 patent/WO2000052009A1/de not_active Ceased
- 2000-02-14 PL PL00349368A patent/PL349368A1/xx not_active Application Discontinuation
- 2000-02-14 PT PT00909166T patent/PT1155018E/pt unknown
- 2000-02-14 DK DK00909166T patent/DK1155018T3/da active
- 2000-02-14 BR BR0008493-0A patent/BR0008493A/pt not_active Application Discontinuation
- 2000-02-14 HU HU0200006A patent/HUP0200006A3/hu unknown
- 2000-02-14 AU AU31543/00A patent/AU763003B2/en not_active Ceased
- 2000-02-14 UA UA2001096578A patent/UA70356C2/uk unknown
2001
- 2001-07-31 ZA ZA200106289A patent/ZA200106289B/en unknown
- 2001-08-02 IL IL144702A patent/IL144702A/en not_active IP Right Cessation
- 2001-08-21 NO NO20014061A patent/NO320191B1/no unknown

Also Published As

Publication number	Publication date
KR20010089630A (ko)	2001-10-06
DE50000700D1 (de)	2002-12-05
NO320191B1 (no)	2005-11-07
UA70356C2 (uk)	2004-10-15
DE19908449A1 (de)	2000-08-31
HUP0200006A3 (en)	2002-08-28
HUP0200006A2 (en)	2002-06-29
KR100756471B1 (ko)	2007-09-07
WO2000052009A1 (de)	2000-09-08
HK1044948B (zh)	2005-10-14
IL144702A (en)	2006-07-05
CZ20013064A3 (cs)	2002-01-16
ES2181644T3 (es)	2003-03-01
SK11952001A3 (sk)	2001-12-03
NZ513750A (en)	2001-09-28
IL144702A0 (en)	2002-06-30
AU763003B2 (en)	2003-07-10
PT1155018E (pt)	2003-02-28
JP2002538158A (ja)	2002-11-12
EP1155018A1 (de)	2001-11-21
AU3154300A (en)	2000-09-21
CZ299700B6 (cs)	2008-10-22
PL349368A1 (en)	2002-07-15
TR200102434T2 (tr)	2002-03-21
CA2362801A1 (en)	2000-09-08
NO20014061D0 (no)	2001-08-21
US6649762B1 (en)	2003-11-18
NO20014061L (no)	2001-08-21
ZA200106289B (en)	2002-07-31
RU2248356C2 (ru)	2005-03-20
CN1191253C (zh)	2005-03-02
BR0008493A (pt)	2002-02-05
SK285562B6 (sk)	2007-03-01
CN1342160A (zh)	2002-03-27
HK1044948A1 (en)	2002-11-08
ATE226952T1 (de)	2002-11-15
EP1155018B1 (de)	2002-10-30

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