DK1165584T3 - 2'-substitueret RNA fremstilling - Google Patents

2'-substitueret RNA fremstilling

Info

Publication number
DK1165584T3
DK1165584T3 DK00909534T DK00909534T DK1165584T3 DK 1165584 T3 DK1165584 T3 DK 1165584T3 DK 00909534 T DK00909534 T DK 00909534T DK 00909534 T DK00909534 T DK 00909534T DK 1165584 T3 DK1165584 T3 DK 1165584T3
Authority
DK
Denmark
Prior art keywords
compound
formula
rna preparation
substituted rna
sup
Prior art date
Application number
DK00909534T
Other languages
Danish (da)
English (en)
Inventor
Colin Bernard Reese
Quanlai Song
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Application granted granted Critical
Publication of DK1165584T3 publication Critical patent/DK1165584T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00909534T 1999-03-19 2000-03-15 2'-substitueret RNA fremstilling DK1165584T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9906328.1A GB9906328D0 (en) 1999-03-19 1999-03-19 2-Substituted RNA preparation
PCT/GB2000/000965 WO2000056747A1 (en) 1999-03-19 2000-03-15 2'-substituted rna preparation

Publications (1)

Publication Number Publication Date
DK1165584T3 true DK1165584T3 (da) 2004-05-17

Family

ID=10849939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00909534T DK1165584T3 (da) 1999-03-19 2000-03-15 2'-substitueret RNA fremstilling

Country Status (12)

Country Link
US (1) US6884881B1 (de)
EP (1) EP1165584B1 (de)
JP (1) JP2002540117A (de)
KR (1) KR20020013511A (de)
AT (1) ATE258187T1 (de)
AU (1) AU3181600A (de)
CA (1) CA2362714A1 (de)
DE (1) DE60007848T2 (de)
DK (1) DK1165584T3 (de)
ES (1) ES2215032T3 (de)
GB (1) GB9906328D0 (de)
WO (1) WO2000056747A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2254306T3 (es) * 2000-10-25 2006-06-16 F. Hoffmann-La Roche Ag Amplificacion usando cebadores modificados.
KR100480498B1 (ko) * 2002-05-24 2005-04-06 학교법인 포항공과대학교 뉴클레오시드를 이용한 저분자 유기 젤레이터 및 그합성방법
CN102993255B (zh) * 2011-09-19 2016-02-10 上海兆维科技发展有限公司 2’-o-(2-甲氧乙基)-5-甲基尿苷和2’-o-(2-甲氧乙基)-5-甲基胞苷及其衍生物的制备及其纯化方法
CN114369124B (zh) * 2022-01-21 2024-03-26 北京瑞博奥医药科技有限公司 一种2`-位取代嘧啶类核苷的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0767657A4 (de) 1994-06-22 1999-01-20 Nexstar Pharmaceuticals Inc Neues verfahren zur herstellung von bekannten und neuen 2'-modifizierten nukleosiden durch intramolekulare nukleophile substitution
AU5359496A (en) * 1995-03-06 1996-09-23 Isis Pharmaceuticals, Inc. Improved process for the synthesis of 2'-o-substituted pyrimidines and oligomeric compounds therefrom

Also Published As

Publication number Publication date
EP1165584B1 (de) 2004-01-21
EP1165584A1 (de) 2002-01-02
US6884881B1 (en) 2005-04-26
GB9906328D0 (en) 1999-05-12
CA2362714A1 (en) 2000-09-28
DE60007848T2 (de) 2004-12-30
ATE258187T1 (de) 2004-02-15
KR20020013511A (ko) 2002-02-20
AU3181600A (en) 2000-10-09
JP2002540117A (ja) 2002-11-26
ES2215032T3 (es) 2004-10-01
DE60007848D1 (de) 2004-02-26
WO2000056747A1 (en) 2000-09-28

Similar Documents

Publication Publication Date Title
MXPA03004920A (es) Pirimidinas inhibidoras de metaloproteinasas de matriz.
MXPA04001323A (es) Dihidro-3-halo-1h-pirazol-5-carboxilatos sustituidos, su preparacion y uso.
ES2195510T3 (es) Derivados de imidazopiridina y procedimiento para prepararlos.
HUP0303166A2 (hu) Eljárás 2-(6-helyettesített 1,3-dioxán-4-il)-ecetsav-származékok előállítására
GB9815163D0 (en) Compounds
EP1106607A3 (de) Urazil Verbindungen und deren Verwendung
EP1465488A4 (de) Arylamine als hemmer der bindung von chemokinen an us28
WO1995018821A3 (en) Novel antiandrogenic agents and related pharmaceutical compositions and methods of use
GR1003795B (el) Μεθοδος παρασκευης της σιταλοπραμης.
DK1204658T3 (da) Benzofurylpiperazin-serotoninagonister
DK1165584T3 (da) 2'-substitueret RNA fremstilling
BG105766A (en) New process for preparing pesticidal intermediates
BG107051A (en) Method for the preparation of citalopram
PT1317455E (pt) Processo para a preparacao de um composto de imidazopiridina substituido
ATE229538T1 (de) 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose
PT1165543E (pt) Processo para a preparacao de acido ¬s-(r*,s*)|-beta-¬¬¬1-¬1-oxo-3-(4-piperidinil)propil|-3-piperidinil|-carbonil|amino|-3-piridinopropanoico e derivados
MXPA04003086A (es) Proceso para sintesis estereoselectiva de 2-hidroximetil-cromanos.
DK0779895T3 (da) Forbedret fremgangsmåde til fremstilling af sidekædederivater af cyclohexapeptidyl-lipopeptider
AU2003264895A8 (en) Process for the preparation of fluorohaloalkanes
DE60004669D1 (de) Indolocarbazolalkaloide aus einer marinen actinomycete
DK1054872T3 (da) Fremgangsmåde til fremstilling af alkoxytriazolinoner
IT1298541B1 (it) Processo per la preparazione di s-alchilcisteine
DE60007984D1 (de) Antioxidantien, verfahren zu ihrer herstellung und ihre verwendungen
PT1423385E (pt) Intermediários para preparar conjugados inibidores da neuraminidase
TR200001161A2 (tr) 8-Siklopentil-6-etil-3-[ikame edilmiş]-5, 8-Dihidro-4H-1, 2, 3A, 7, 8-Pentaaza-As-Indasenlerin hazırlandığı işlem ve burada yararlı ara bağlar.