DK1171100T3 - Solubiliseret farmaceutisk komposition til parenteral administration - Google Patents

Solubiliseret farmaceutisk komposition til parenteral administration

Info

Publication number: DK1171100T3
Authority: DK; Denmark
Prior art keywords: polyethylene glycol; active substance; pharmaceutical composition; parenteral administration; solubilizer
Prior art date: 1999-04-13

Application number

DK00922609T

Other languages

English (en)

Inventor

Erik Johannes Didriksen

Anette Leth Gerlach

Original Assignee

Leo Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-13

Filing date

2000-04-05

Publication date

2003-11-24

2000-04-05 Application filed by Leo Pharma As filed Critical Leo Pharma As

2003-11-24 Application granted granted Critical

2003-11-24 Publication of DK1171100T3 publication Critical patent/DK1171100T3/da

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
238000007911 parenteral administration Methods 0.000 title 1
239000002202 Polyethylene glycol Substances 0.000 abstract 3
239000013543 active substance Substances 0.000 abstract 3
229920001223 polyethylene glycol Polymers 0.000 abstract 3
239000002904 solvent Substances 0.000 abstract 3
229930003316 Vitamin D Natural products 0.000 abstract 2
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
235000019166 vitamin D Nutrition 0.000 abstract 2
239000011710 vitamin D Substances 0.000 abstract 2
150000003710 vitamin D derivatives Chemical class 0.000 abstract 2
229940046008 vitamin d Drugs 0.000 abstract 2
230000002378 acidificating effect Effects 0.000 abstract 1
239000008135 aqueous vehicle Substances 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
-1 fatty acid ester Chemical class 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK00922609T 1999-04-13 2000-04-05 Solubiliseret farmaceutisk komposition til parenteral administration DK1171100T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900486		1999-04-13
PCT/EP2000/003022 WO2000061112A2 (en)	1999-04-13	2000-04-05	Solubilized pharmaceutical composition for parenteral administration

Publications (1)

Publication Number	Publication Date
DK1171100T3 true DK1171100T3 (da)	2003-11-24

Family

ID=8094111

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00922609T DK1171100T3 (da)	1999-04-13	2000-04-05	Solubiliseret farmaceutisk komposition til parenteral administration

Country Status (16)

Country	Link
EP (1)	EP1171100B1 (da)
JP (1)	JP2003511348A (da)
KR (1)	KR20010111585A (da)
CN (1)	CN1226999C (da)
AT (1)	ATE245968T1 (da)
AU (1)	AU768785B2 (da)
CA (1)	CA2369587C (da)
DE (1)	DE60004191T2 (da)
DK (1)	DK1171100T3 (da)
ES (1)	ES2206225T3 (da)
HK (1)	HK1049789B (da)
HU (1)	HUP0203903A3 (da)
PL (1)	PL356968A1 (da)
PT (1)	PT1171100E (da)
RU (1)	RU2001130462A (da)
WO (1)	WO2000061112A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999049870A1 (en)	1998-03-27	1999-10-07	Oregon Health Sciences University	Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders
US7148211B2 (en)	2002-09-18	2006-12-12	Genzyme Corporation	Formulation for lipophilic agents
GB0513984D0 (en) *	2005-07-07	2005-08-17	Teva Pharma	Dosage form
US20090203709A1 (en) *	2008-02-07	2009-08-13	Abbott Laboratories	Pharmaceutical Dosage Form For Oral Administration Of Tyrosine Kinase Inhibitor
BRPI0918253A2 (pt) *	2008-09-12	2015-12-15	Critical Pharmaceuticals Ltd	aperfeicoamento na absorcao de agentes terapeuticos atraves das membranas mucosas ou da pele
CN104168900A (zh) *	2012-02-06	2014-11-26	梅里亚有限公司	包含全身性地起作用的活性剂的杀寄生虫口服兽用组合物、方法及其用途
ES2698403T3 (es) *	2012-12-27	2019-02-04	Pharmathen Sa	Composición farmacéutica inyectable estable de agonista de receptor de vitamina D y proceso para su preparación
AR100873A1 (es) *	2014-06-17	2016-11-09	Clariant Produkte Deutschland Gmbh	Proceso para el desgomado de composiciones que contienen triglicéridos
KR101983654B1 (ko) *	2018-07-24	2019-05-29	한국과학기술원	Cfc 증후군 환자의 발달 저해를 완화할 수 있는 치료용 조성물
PL3880168T3 (pl) *	2018-11-26	2024-12-16	Orphanix Gmbh	Pediatryczne wodne preparaty retinolu
CN115177586A (zh) *	2022-08-31	2022-10-14	江苏知原药业股份有限公司	一种卡泊三醇组合物
CN115350151B (zh) *	2022-09-29	2023-09-12	湖北欣泽霏药业有限公司	一种高稳定性阿法骨化醇液体口服制剂及其制备方法
CN119185194B (zh) *	2024-09-29	2025-04-25	安徽益普克医药科技发展有限公司	维生素d3注射液药物组合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1062389B (de) *	1958-02-11	1959-07-30	Wander Ag Dr A	Verfahren zur Herstellung von sterilen, Kalziumsalze enthaltenden Vitamin-D-Loesungen
GB1123433A (en) *	1964-09-28	1968-08-14	Eastman Kodak Co	Intramuscularly injectable vitamin a preparation
AU5861396A (en) *	1995-05-19	1996-11-29	Abbott Laboratories	Stable aqueous formulations of 1alpha,25-dihydroxycholecalci ferol for parenteral administration
DE19609477A1 (de) *	1996-03-11	1997-09-18	Basf Ag	Stabile wäßrige Solubilisate von Carotinoiden und Vitamine
US6458373B1 (en) *	1997-01-07	2002-10-01	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs

2000
- 2000-04-05 AU AU42939/00A patent/AU768785B2/en not_active Ceased
- 2000-04-05 KR KR1020017013042A patent/KR20010111585A/ko not_active Ceased
- 2000-04-05 DK DK00922609T patent/DK1171100T3/da active
- 2000-04-05 CN CNB008070113A patent/CN1226999C/zh not_active Expired - Fee Related
- 2000-04-05 ES ES00922609T patent/ES2206225T3/es not_active Expired - Lifetime
- 2000-04-05 PL PL00356968A patent/PL356968A1/xx not_active Application Discontinuation
- 2000-04-05 JP JP2000610445A patent/JP2003511348A/ja active Pending
- 2000-04-05 PT PT00922609T patent/PT1171100E/pt unknown
- 2000-04-05 HK HK03101869.3A patent/HK1049789B/zh not_active IP Right Cessation
- 2000-04-05 WO PCT/EP2000/003022 patent/WO2000061112A2/en not_active Ceased
- 2000-04-05 RU RU2001130462A patent/RU2001130462A/ru unknown
- 2000-04-05 EP EP00922609A patent/EP1171100B1/en not_active Expired - Lifetime
- 2000-04-05 AT AT00922609T patent/ATE245968T1/de active
- 2000-04-05 HU HU0203903A patent/HUP0203903A3/hu unknown
- 2000-04-05 DE DE60004191T patent/DE60004191T2/de not_active Expired - Lifetime
- 2000-04-05 CA CA002369587A patent/CA2369587C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1382036A (zh)	2002-11-27
HK1049789B (zh)	2006-02-24
PT1171100E (pt)	2003-11-28
ES2206225T3 (es)	2004-05-16
WO2000061112A3 (en)	2002-09-26
HUP0203903A2 (hu)	2003-03-28
HUP0203903A3 (en)	2004-09-28
RU2001130462A (ru)	2003-06-20
WO2000061112A2 (en)	2000-10-19
EP1171100B1 (en)	2003-07-30
AU4293900A (en)	2000-11-14
AU768785B2 (en)	2004-01-08
DE60004191T2 (de)	2004-04-22
ATE245968T1 (de)	2003-08-15
PL356968A1 (en)	2004-07-12
EP1171100A1 (en)	2002-01-16
CN1226999C (zh)	2005-11-16
HK1049789A1 (en)	2003-05-30
DE60004191D1 (de)	2003-09-04
CA2369587A1 (en)	2000-10-19
KR20010111585A (ko)	2001-12-19
JP2003511348A (ja)	2003-03-25
CA2369587C (en)	2009-12-22

Publication	Publication Date	Title
PT1171100E (pt)	2003-11-28	Composicao farmaceutica solubilizada para administracao parenteral
DK1163234T3 (da)	2006-02-27	Farmaceutiske formuleringer med forbedret vandoplöselighed
BR0210505A (pt)	2004-05-18	Formulações auto-emulsionantes de inibidores da proteìna de transferência de ésteres de colesterilo
DK0904064T3 (da)	2001-12-17	Orale farmaceutiske præparater indeholdende kønshormoner
AP2001002217A0 (en)	2001-09-30	Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids.
DE60105448D1 (de)	2004-10-14	Feste dispersionen mit nitrataktiven wirkstoffen
UY25055A1 (es)	2000-12-29	Formulaciones farmacéuticas que contienen voriconazol
KR940703689A (ko)	1994-12-12	성장호르몬과 아스파라진으로 이루어지는 안정화된 약학제제(a stabil-ized pharmaceutical formulation comprising growth gormone and asparagine)
BR0206984A (pt)	2004-02-03	Composições de depósito injetáveis e uso destas
KR970706017A (ko)	1997-11-03	안정한 알파 인터페론 수용액 제형(Stable, aqueous alfainterfer on solution for mulations)
NO20030533L (no)	2003-02-26	Vandige farmasöytiske preparater
BR0007294A (pt)	2002-08-27	Formulações farmacêuticas aperfeiçoadas
DE69637012D1 (de)	2007-05-16	Waessrige Formulierung enthaltend TFPI und Lösungsvermittlers
DK1259226T3 (da)	2006-08-21	Anæstetiske formuleringer
BRPI0418115A (pt)	2007-04-17	formulação lìquida estável de hormÈnio de crescimento
FI955403A0 (fi)	1995-11-09	Valeltavia koostumuksia, jotka sisältävät polymeerimateriaalia, glykoleja ja glyseridejä
BR0215303A (pt)	2005-04-05	Formulações farmacêuticas de base aquosa de pró-drogas solúveis em água de propofol
ES2187820T3 (es)	2003-06-16	Formulaciones farmaceuticas de factor de liberacion de la corticotrop ina que tiene una estabilidad en su forma liquida.
PE20000018A1 (es)	2000-04-14	Composiciones farmaceuticas a base de dalfopristina y de quinupristina y su preparacion
KR930001903A (ko)	1993-02-22	유비데카레논 경구용 수용액 제제
EP1623697A4 (en)	2008-03-19	COSMETIC OIL IN WATER EMULSION
DE60127839D1 (de)	2007-05-24	Pflaster mit 4-biphenylessigsäure
EA200200415A1 (ru)	2002-10-31	Композиция фармацевтического носителя
ES2092559T3 (es)	1996-12-01	Formulacion farmaceutica que contiene penciclovir.
TW328049B (en)	1998-03-11	Penciclover/propylene glycol composition