DK1173176T3 - Anvendelse af polycycliske 2-aminothiazolsystemer til fremstilling af medikamenter til forebyggelse eller behandling af obesitas - Google Patents

Anvendelse af polycycliske 2-aminothiazolsystemer til fremstilling af medikamenter til forebyggelse eller behandling af obesitas

Info

Publication number
DK1173176T3
DK1173176T3 DK00905028T DK00905028T DK1173176T3 DK 1173176 T3 DK1173176 T3 DK 1173176T3 DK 00905028 T DK00905028 T DK 00905028T DK 00905028 T DK00905028 T DK 00905028T DK 1173176 T3 DK1173176 T3 DK 1173176T3
Authority
DK
Denmark
Prior art keywords
treatment
aminothiazole
obesity
polycyclic
systems
Prior art date
Application number
DK00905028T
Other languages
English (en)
Inventor
Gerhard Jaehne
Karl Geisen
Hans-Jochen Lang
Martin Bickel
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK1173176T3 publication Critical patent/DK1173176T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK00905028T 1999-02-26 2000-02-05 Anvendelse af polycycliske 2-aminothiazolsystemer til fremstilling af medikamenter til forebyggelse eller behandling af obesitas DK1173176T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19908537A DE19908537A1 (de) 1999-02-26 1999-02-26 Verwendung von polycyclischen 2-Amino-Thiazol Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas

Publications (1)

Publication Number Publication Date
DK1173176T3 true DK1173176T3 (da) 2004-09-27

Family

ID=7899081

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00905028T DK1173176T3 (da) 1999-02-26 2000-02-05 Anvendelse af polycycliske 2-aminothiazolsystemer til fremstilling af medikamenter til forebyggelse eller behandling af obesitas

Country Status (16)

Country Link
US (1) US6476059B1 (da)
EP (1) EP1173176B1 (da)
JP (1) JP4728483B2 (da)
KR (1) KR20020002394A (da)
CN (1) CN1161120C (da)
AT (1) ATE267597T1 (da)
AU (1) AU766295B2 (da)
BR (1) BR0008557A (da)
CA (1) CA2362554A1 (da)
DE (2) DE19908537A1 (da)
DK (1) DK1173176T3 (da)
ES (1) ES2218122T3 (da)
HK (1) HK1045809B (da)
PT (1) PT1173176E (da)
WO (1) WO2000051602A1 (da)
ZA (1) ZA200106199B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19908538A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen
JP2002543067A (ja) * 1999-04-22 2002-12-17 シナプティック・ファーマスーティカル・コーポレーション 選択的なｎｐｙ（ｙ５）のアンタゴニスト
AU2001246494A1 (en) * 2000-03-03 2001-09-12 Novartis Ag Condensed thiazolamines and their use as neuropeptide y5 antagonists
US7732484B2 (en) * 2000-08-01 2010-06-08 University Of Virginia Patent Foundation Use of selective adenosine A1 receptor allosteric enhancers to manipulate angiogenesis
US7485655B2 (en) * 2002-01-16 2009-02-03 University Of Virginia Patent Foundation 2-Aminothiazole allosteric enhancers of A1 adenosine receptors
WO2004110338A2 (en) * 2003-06-12 2004-12-23 Biomas Ltd. Methods of treating obesity and related disorders using tellurium and selenium compounds
WO2006013054A1 (en) * 2004-08-05 2006-02-09 F. Hoffmann-La Roche Ag Substituted n-acyl-2-aminothiazoles
WO2006080406A1 (ja) * 2005-01-28 2006-08-03 Taisho Pharmaceutical Co., Ltd. 三環性化合物
ES2480994T3 (es) 2008-03-31 2014-07-29 Genentech, Inc. Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso
US8263633B2 (en) 2009-09-28 2012-09-11 F. Hoffman-La Roche Ag Benzoxepin PI3K inhibitor compounds and methods of use
TWI423980B (zh) 2009-09-28 2014-01-21 Hoffmann La Roche 苯并氧氮呯ｐｉ３ｋ抑制劑化合物及使用方法
KR20140032383A (ko) 2011-03-21 2014-03-14 에프. 호프만-라 로슈 아게 Pi3k p110 델타에 대하여 선택적인 벤즈옥사제핀 화합물 및 이의 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507868A (en) * 1968-10-21 1970-04-21 Sandoz Ag Imidazo(2,1-b)thiazoles and thiazolo(3,2-a)pyrimidines
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
JPS5334471A (en) * 1976-09-10 1978-03-31 Toshiba Corp Manufacture for semiconductor device
CA1292226C (en) * 1986-01-16 1991-11-19 Terumi Hachiya Indenothiazole derivative and process for preparing the same
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
DE19831878C2 (de) * 1998-07-17 2001-05-17 Aventis Pharma Gmbh Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908538A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen

Also Published As

Publication number Publication date
ES2218122T3 (es) 2004-11-16
HK1045809A1 (en) 2002-12-13
DE19908537A1 (de) 2000-08-31
ATE267597T1 (de) 2004-06-15
KR20020002394A (ko) 2002-01-09
BR0008557A (pt) 2001-12-18
CA2362554A1 (en) 2000-09-08
ZA200106199B (en) 2002-03-06
EP1173176B1 (de) 2004-05-26
EP1173176A1 (de) 2002-01-23
DE50006603D1 (de) 2004-07-01
JP2002538117A (ja) 2002-11-12
WO2000051602A1 (de) 2000-09-08
CN1161120C (zh) 2004-08-11
JP4728483B2 (ja) 2011-07-20
HK1045809B (zh) 2005-04-22
AU2670300A (en) 2000-09-21
US6476059B1 (en) 2002-11-05
PT1173176E (pt) 2004-09-30
CN1349404A (zh) 2002-05-15
AU766295B2 (en) 2003-10-16

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