DK1179176T3 - Fremgangsmåde til detektion af antigenspecifikke T-celler - Google Patents

Fremgangsmåde til detektion af antigenspecifikke T-celler

Info

Publication number
DK1179176T3
DK1179176T3 DK00923290T DK00923290T DK1179176T3 DK 1179176 T3 DK1179176 T3 DK 1179176T3 DK 00923290 T DK00923290 T DK 00923290T DK 00923290 T DK00923290 T DK 00923290T DK 1179176 T3 DK1179176 T3 DK 1179176T3
Authority
DK
Denmark
Prior art keywords
mhc
cells
molecules
clusters
complexes
Prior art date
Application number
DK00923290T
Other languages
English (en)
Inventor
Zeling Cai
Michael Jackson
Homero Sepulveda
Jing-Feng Huang
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1179176T3 publication Critical patent/DK1179176T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK00923290T 1999-04-16 2000-04-13 Fremgangsmåde til detektion af antigenspecifikke T-celler DK1179176T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12980599P 1999-04-16 1999-04-16

Publications (1)

Publication Number Publication Date
DK1179176T3 true DK1179176T3 (da) 2006-08-07

Family

ID=22441679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00923290T DK1179176T3 (da) 1999-04-16 2000-04-13 Fremgangsmåde til detektion af antigenspecifikke T-celler

Country Status (13)

Country Link
US (2) US20020049302A1 (da)
EP (1) EP1179176B1 (da)
JP (1) JP4673978B2 (da)
AT (1) ATE322683T1 (da)
AU (1) AU763757B2 (da)
CA (1) CA2370557C (da)
CY (1) CY1105064T1 (da)
DE (1) DE60027152T2 (da)
DK (1) DK1179176T3 (da)
ES (1) ES2261197T3 (da)
HK (1) HK1041312B (da)
PT (1) PT1179176E (da)
WO (1) WO2000063690A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2306771T3 (es) * 2001-02-20 2008-11-16 Ortho Mcneil Pharm Inc Un metodo de terapia celular para tratamiento de tumores.
US20040071671A1 (en) * 2001-02-20 2004-04-15 Leturcq Didier J. Cell therapy method for the treatment of tumors
WO2004084838A2 (en) * 2003-03-24 2004-10-07 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Identification, quantification, and characterization of t cells and t cell antigens
GB0502065D0 (en) * 2005-02-01 2005-03-09 Queen Mary & Westfield College Assay method
CN101548008B (zh) 2006-10-04 2013-04-17 詹森药业有限公司 失活的人工抗原提呈细胞的制备及其在细胞疗法中的用途
EP2155782A2 (en) 2007-03-26 2010-02-24 Dako Denmark A/S Mhc peptide complexes and uses thereof in infectious diseases
WO2009003493A2 (en) 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
WO2009039854A2 (en) 2007-09-27 2009-04-02 Dako Denmark A/S Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
WO2010009735A2 (en) * 2008-07-23 2010-01-28 Dako Denmark A/S Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
WO2020127222A2 (en) 2018-12-17 2020-06-25 Immudex Aps Panel comprising borrelia mhc multimers
US20230241105A1 (en) * 2020-06-11 2023-08-03 La Jolla Institute For Immunology Methods of use of allergen-specific t cells in allergy and asthma
KR102751115B1 (ko) * 2020-10-20 2025-01-09 연세대학교 산학협력단 단일 세포 분석법을 이용한 tcr-항원의 특이성을 확인하는 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194425A (en) * 1988-06-23 1993-03-16 Anergen, Inc. Mhc-mediated toxic conjugates useful in ameliorating autoimmunity
US5734023A (en) * 1991-11-19 1998-03-31 Anergen Inc. MHC class II β chain/peptide complexes useful in ameliorating deleterious immune responses
US5583031A (en) * 1992-02-06 1996-12-10 President And Fellows Of Harvard College Empty major histocompatibility class II heterodimers
US5314813A (en) * 1992-02-19 1994-05-24 Scripps Research Institute Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines
CN1112933A (zh) * 1994-01-20 1995-12-06 伯伦格·曼海姆有限公司 抗原特异性活化t淋巴细胞，其检测和用途
US5820866A (en) * 1994-03-04 1998-10-13 National Jewish Center For Immunology And Respiratory Medicine Product and process for T cell regulation
US5595881A (en) * 1994-08-09 1997-01-21 Anergen, Inc. Method for the detection of antigen presenting cells
US5858777A (en) * 1995-09-08 1999-01-12 Geron Corporation Methods and reagents for regulating telomere length and telomerase activity
US5869270A (en) * 1996-01-31 1999-02-09 Sunol Molecular Corporation Single chain MHC complexes and uses thereof
ES2277358T3 (es) * 1996-09-06 2007-07-01 Ortho-Mcneil Pharmaceutical, Inc. Purificacion de celulas t especificas de antigeno.
GB9718745D0 (en) * 1996-12-03 1997-11-12 Medical Res Council Improvements in or relating to screening for carcinoma
US6245564B1 (en) * 1997-01-23 2001-06-12 Cornell Research Foundation, Inc. Method for separating cells
AU741130B2 (en) * 1997-09-16 2001-11-22 Oregon Health Sciences University Recombinant MHC molecules useful for manipulation of antigen-specific T-cells
US6790662B1 (en) * 1999-03-12 2004-09-14 Ortho-Mcneil Pharmaceutical, Inc. Method of isolating CD8+ cells, and related hybridoma cells antibodies and polypeptides

Also Published As

Publication number Publication date
AU763757B2 (en) 2003-07-31
EP1179176A4 (en) 2002-09-25
ATE322683T1 (de) 2006-04-15
DE60027152T2 (de) 2007-01-04
US20020049302A1 (en) 2002-04-25
DE60027152D1 (de) 2006-05-18
PT1179176E (pt) 2006-07-31
CA2370557C (en) 2007-12-04
CY1105064T1 (el) 2009-11-04
HK1041312A1 (en) 2002-07-05
US20060234310A1 (en) 2006-10-19
AU4344300A (en) 2000-11-02
WO2000063690A1 (en) 2000-10-26
HK1041312B (en) 2006-09-29
JP2002542483A (ja) 2002-12-10
EP1179176A1 (en) 2002-02-13
CA2370557A1 (en) 2000-10-26
ES2261197T3 (es) 2006-11-16
JP4673978B2 (ja) 2011-04-20
EP1179176B1 (en) 2006-04-05

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