DK1189637T3 - Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter - Google Patents

Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter

Info

Publication number
DK1189637T3
DK1189637T3 DK00931720T DK00931720T DK1189637T3 DK 1189637 T3 DK1189637 T3 DK 1189637T3 DK 00931720 T DK00931720 T DK 00931720T DK 00931720 T DK00931720 T DK 00931720T DK 1189637 T3 DK1189637 T3 DK 1189637T3
Authority
DK
Denmark
Prior art keywords
orally administered
bioavailability
products
improve
administered drugs
Prior art date
Application number
DK00931720T
Other languages
English (en)
Inventor
Johannes Henricus Ma Schellens
Alfred Hermanus Schinkel
Original Assignee
Cancer Res Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Ventures Ltd filed Critical Cancer Res Ventures Ltd
Application granted granted Critical
Publication of DK1189637T3 publication Critical patent/DK1189637T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00931720T 1999-05-17 2000-05-17 Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter DK1189637T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1012066 1999-05-17
NL1012481 1999-06-30

Publications (1)

Publication Number Publication Date
DK1189637T3 true DK1189637T3 (da) 2006-12-11

Family

ID=26642978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00931720T DK1189637T3 (da) 1999-05-17 2000-05-17 Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter

Country Status (10)

Country Link
US (2) US7030132B2 (da)
EP (2) EP1749540B1 (da)
AT (2) ATE484295T1 (da)
AU (1) AU4955200A (da)
CY (1) CY1105795T1 (da)
DE (2) DE60030283T2 (da)
DK (1) DK1189637T3 (da)
ES (1) ES2270834T3 (da)
PT (1) PT1189637E (da)
WO (1) WO2000069390A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
DE60030283T2 (de) * 1999-05-17 2007-09-20 Cancer Research Ventures Ltd. Zusammensetzungen zur erhöhung der bioverfügbarkeit von oral verabreichten pharmazeutischen verbindungen
HU0100947D0 (en) * 2001-03-02 2001-05-28 Solvo Kft Screening system based on expression of abcg2 half transporter protein in an expression system free of other abc-transporters, abcg2 homodimers
US7169763B2 (en) * 2002-02-22 2007-01-30 Oliver Yoa-Pu Hu Cytochrome P450 3A inhibitors and enhancers
WO2006012958A2 (en) * 2004-07-01 2006-02-09 The Netherlands Cancer Institute Combination comprising a bcrp inhibitor and 4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide
US8518022B2 (en) 2004-08-27 2013-08-27 Medimetrics Personalized Drug Delivery, Inc. Electronically and remotely controlled pill and system for delivering at least one medicament
US20090234331A1 (en) * 2004-11-29 2009-09-17 Koninklijke Philips Electronics, N.V. Electronically controlled pill and system having at least one sensor for delivering at least one medicament
WO2006065125A1 (en) * 2004-12-16 2006-06-22 Het Nederlands Kanter Instituut Means and methods for determining and/or influencing transportation
WO2009083042A1 (en) * 2007-12-31 2009-07-09 Olaf Van Tellingen Methods and means for the treatment of cancer
US20100331827A1 (en) * 2008-02-18 2010-12-30 Koninklijke Philips Electronics N.V. Administration of drugs to a patient
WO2009122323A1 (en) * 2008-03-31 2009-10-08 Koninklijke Philips Electronics N.V. Method of preparing a swallowable capsule comprising a sensor
EP2279011B1 (en) 2008-04-30 2017-10-25 Siemens Medical Solutions USA, Inc. Substrate based pet imaging agents
JP5500600B2 (ja) * 2008-06-19 2014-05-21 コーニンクレッカ フィリップス エヌ ヴェ 湿った環境における粉状薬物の供給のためのデバイス
RU2011102576A (ru) * 2008-06-25 2012-07-27 Конинклейке Филипс Электроникс Н.В. (Nl) Электронная таблетка, содержащая множество емкостей с лекарственным средствами
JP5497176B2 (ja) 2009-08-12 2014-05-21 コーニンクレッカ フィリップス エヌ ヴェ 圧縮可能な薬品貯槽を備える薬品送出装置
CN106432490B (zh) * 2016-09-14 2020-01-07 北京大学 一种abcg2单克隆抗体及其用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
KR100220538B1 (ko) 1991-01-11 1999-09-15 뮈쉘 쥐르밀 아크리딘 유도체
US5663179A (en) * 1992-07-10 1997-09-02 Laboratoires Glaxo Sa Certain isoquinoline derivatives having anti-tumor properties
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
CZ104197A3 (en) 1994-10-05 1997-09-17 Glaxo Wellcome Inc Pharmaceutical preparation
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
US6245805B1 (en) 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
GB9710612D0 (en) * 1997-05-23 1997-07-16 Glaxo Group Ltd Synthesis of acridine derivatives
CN1261275A (zh) 1997-05-27 2000-07-26 巴克·诺顿药物有限公司 给予病人口服紫杉烷类药物的方法和组合物
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
ATE359291T1 (de) * 1998-02-05 2007-05-15 Univ Maryland Brustkrebsresistenzprotein (bcrp) und für dieses kodierende dna
CA2300892A1 (en) 1998-06-18 1999-12-23 The George Washington University Methods of administering camptothecin compounds for the treatment of cancer with reduced side effects
HUP0103314A3 (en) 1998-08-05 2002-07-29 Aventis Pharma Sa Use of camptothecin derivatives, with reduced gastrointestinal toxicity
DE60030283T2 (de) * 1999-05-17 2007-09-20 Cancer Research Ventures Ltd. Zusammensetzungen zur erhöhung der bioverfügbarkeit von oral verabreichten pharmazeutischen verbindungen
US6521635B1 (en) * 2000-01-20 2003-02-18 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of MXR transport by acridine derivatives

Also Published As

Publication number Publication date
CY1105795T1 (el) 2011-02-02
EP1749540A3 (en) 2007-05-30
DE60045114D1 (de) 2010-11-25
DE60030283D1 (de) 2006-10-05
ES2270834T3 (es) 2007-04-16
EP1749540B1 (en) 2010-10-13
EP1189637B1 (en) 2006-08-23
US20060128743A1 (en) 2006-06-15
US20020128282A1 (en) 2002-09-12
WO2000069390A3 (en) 2001-12-13
EP1189637A2 (en) 2002-03-27
ATE337016T1 (de) 2006-09-15
WO2000069390A2 (en) 2000-11-23
DE60030283T2 (de) 2007-09-20
AU4955200A (en) 2000-12-05
PT1189637E (pt) 2007-01-31
US7030132B2 (en) 2006-04-18
EP1749540A2 (en) 2007-02-07
ATE484295T1 (de) 2010-10-15

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