DK1192156T3 - Bispidinforbindelser, som er egnede til behandling af hjertearytmier - Google Patents

Bispidinforbindelser, som er egnede til behandling af hjertearytmier

Info

Publication number
DK1192156T3
DK1192156T3 DK00946588T DK00946588T DK1192156T3 DK 1192156 T3 DK1192156 T3 DK 1192156T3 DK 00946588 T DK00946588 T DK 00946588T DK 00946588 T DK00946588 T DK 00946588T DK 1192156 T3 DK1192156 T3 DK 1192156T3
Authority
DK
Denmark
Prior art keywords
treatment
compounds suitable
cardiac arrhythmias
bispidine compounds
bispidine
Prior art date
Application number
DK00946588T
Other languages
English (en)
Inventor
Magnus Bjoersne
Marianne Frantsi
Kurt-Juergen Hoffmann
Bengt Ohlsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1192156T3 publication Critical patent/DK1192156T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00946588T 1999-06-16 2000-06-15 Bispidinforbindelser, som er egnede til behandling af hjertearytmier DK1192156T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9902269A SE9902269D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds
PCT/SE2000/001252 WO2000076998A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
DK1192156T3 true DK1192156T3 (da) 2004-05-17

Family

ID=20416101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00946588T DK1192156T3 (da) 1999-06-16 2000-06-15 Bispidinforbindelser, som er egnede til behandling af hjertearytmier

Country Status (28)

Country Link
EP (1) EP1192156B1 (da)
JP (1) JP2003502327A (da)
KR (1) KR20020042534A (da)
CN (1) CN1187351C (da)
AR (1) AR024392A1 (da)
AT (1) ATE259809T1 (da)
AU (1) AU762040B2 (da)
BR (1) BR0011667A (da)
CA (1) CA2377395A1 (da)
CZ (1) CZ20014493A3 (da)
DE (1) DE60008377T2 (da)
DK (1) DK1192156T3 (da)
EE (1) EE200100679A (da)
ES (1) ES2214291T3 (da)
HK (1) HK1045689A1 (da)
HU (1) HUP0300244A3 (da)
IL (1) IL146751A0 (da)
IS (1) IS6200A (da)
MX (1) MXPA01012926A (da)
NO (1) NO20016120L (da)
NZ (1) NZ516014A (da)
PL (1) PL353155A1 (da)
PT (1) PT1192156E (da)
SE (1) SE9902269D0 (da)
SK (1) SK18292001A3 (da)
TR (1) TR200103635T2 (da)
WO (1) WO2000076998A1 (da)
ZA (1) ZA200109798B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
RU2228934C1 (ru) * 2003-05-20 2004-05-20 ООО "Исследовательский институт химического разнообразия" Замещенные 3,7-диазобицикло[3.3.1]нонаны, фокусированная библиотека и комбинаторная библиотека

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
JP2003502327A (ja) 2003-01-21
HK1045689A1 (zh) 2002-12-06
AU6032300A (en) 2001-01-02
AR024392A1 (es) 2002-10-02
CN1187351C (zh) 2005-02-02
NO20016120D0 (no) 2001-12-14
SK18292001A3 (sk) 2002-12-03
SE9902269D0 (sv) 1999-06-16
ES2214291T3 (es) 2004-09-16
DE60008377T2 (de) 2004-12-09
MXPA01012926A (es) 2002-07-30
KR20020042534A (ko) 2002-06-05
ZA200109798B (en) 2003-02-28
EP1192156B1 (en) 2004-02-18
CN1370165A (zh) 2002-09-18
PL353155A1 (en) 2003-10-20
TR200103635T2 (tr) 2002-04-22
IS6200A (is) 2001-12-14
CA2377395A1 (en) 2000-12-21
WO2000076998A1 (en) 2000-12-21
CZ20014493A3 (cs) 2002-05-15
ATE259809T1 (de) 2004-03-15
PT1192156E (pt) 2004-06-30
AU762040B2 (en) 2003-06-19
NO20016120L (no) 2002-02-18
EP1192156A1 (en) 2002-04-03
NZ516014A (en) 2003-06-30
BR0011667A (pt) 2002-04-02
WO2000076998B1 (en) 2001-03-08
EE200100679A (et) 2003-02-17
HUP0300244A2 (hu) 2003-06-28
DE60008377D1 (de) 2004-03-25
IL146751A0 (en) 2002-07-25
HUP0300244A3 (en) 2003-12-29

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