DK1206448T3 - Nye vitamin D analoger - Google Patents

Nye vitamin D analoger

Info

Publication number: DK1206448T3
Authority: DK; Denmark
Prior art keywords: analogues; new vitamin; vitamin; phenyl; alkyl
Prior art date: 1999-08-04

Application number

DK00943703T

Other languages

English (en)

Inventor

Claus Aage Bretting

Original Assignee

Leo Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-04

Filing date

2000-07-11

Publication date

2004-08-09

2000-07-11 Application filed by Leo Pharma As filed Critical Leo Pharma As

2004-08-09 Application granted granted Critical

2004-08-09 Publication of DK1206448T3 publication Critical patent/DK1206448T3/da

Links

229930003316 Vitamin D Natural products 0.000 title abstract 2
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
235000019166 vitamin D Nutrition 0.000 title abstract 2
239000011710 vitamin D Substances 0.000 title abstract 2
229940046008 vitamin d Drugs 0.000 title abstract 2
150000003710 vitamin D derivatives Chemical class 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
-1 Vitamin D compounds Chemical class 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
229910052736 halogen Chemical group 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Cell Biology (AREA)
Toxicology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Analytical Chemistry (AREA)
Food Science & Technology (AREA)
Dermatology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Tropical Medicine & Parasitology (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)

DK00943703T 1999-08-04 2000-07-11 Nye vitamin D analoger DK1206448T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14720099P	1999-08-04	1999-08-04
PCT/DK2000/000389 WO2001010829A1 (en)	1999-08-04	2000-07-11	Novel vitamin d analogues

Publications (1)

Publication Number	Publication Date
DK1206448T3 true DK1206448T3 (da)	2004-08-09

Family

ID=22520639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00943703T DK1206448T3 (da)	1999-08-04	2000-07-11	Nye vitamin D analoger

Country Status (19)

Country	Link
US (1)	US6573255B1 (da)
EP (1)	EP1206448B1 (da)
JP (2)	JP2003506435A (da)
KR (1)	KR20020022792A (da)
CN (1)	CN1167678C (da)
AT (1)	ATE265430T1 (da)
AU (1)	AU770771B2 (da)
CA (1)	CA2381910A1 (da)
CZ (1)	CZ2002392A3 (da)
DE (1)	DE60010276T2 (da)
DK (1)	DK1206448T3 (da)
ES (1)	ES2216908T3 (da)
HK (1)	HK1049148B (da)
HU (1)	HUP0202305A3 (da)
NZ (1)	NZ516913A (da)
PL (1)	PL364698A1 (da)
PT (1)	PT1206448E (da)
RU (1)	RU2228928C2 (da)
WO (1)	WO2001010829A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0117645D0 (en) *	2001-07-19	2001-09-12	Isis Innovation	Therapeutic stratergies for prevention and treatment of alzheimers disease
WO2005027930A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	2-alkylene-19-nor-vitamin d derivatives for the treatment of osteosarcoma
US20050074443A1 (en) *	2003-10-03	2005-04-07	Treadwell Benjamin V.	Methods of attenuating autoimmune disease and compositions useful therefor
US8404667B2 (en) *	2006-12-29	2013-03-26	Wisconsin Alumni Research Foundation	Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
KR20100082840A (ko)	2007-09-27	2010-07-20	에스체아 히기에너 프로덕츠 악티에볼라그	클레이결합된 폴리머 겔
CN103922984B (zh) *	2014-04-24	2016-08-24	湖南华腾制药有限公司	西奥骨化醇的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5254799A (en) *	1985-01-18	1993-10-19	Plant Genetic Systems N.V.	Transformation vectors allowing expression of Bacillus thuringiensis endotoxins in plants
DE3715114A1 (de) *	1987-05-06	1988-11-17	Krause Hans	Verfahren und einrichtung zum toxizitaetsnachweis in oberflaechengewaessern sowie in trink- und brauchwasser
GB9206648D0 (en) *	1992-03-26	1992-05-06	Leo Pharm Prod Ltd	Chemical compounds
CA2111521A1 (en) *	1993-12-15	1995-06-16	Stroud Water Research Center, Inc.	Mayfly centroptilum triangulifer as a bioassay organism
JP2002513416A (ja) *	1997-05-22	2002-05-08	セファロン・インコーポレイテッド	ビタミンｄアナログおよびそれらのニューロン効果

2000
- 2000-07-11 AU AU58072/00A patent/AU770771B2/en not_active Ceased
- 2000-07-11 DE DE60010276T patent/DE60010276T2/de not_active Expired - Fee Related
- 2000-07-11 RU RU2002105520/04A patent/RU2228928C2/ru not_active IP Right Cessation
- 2000-07-11 US US10/048,363 patent/US6573255B1/en not_active Expired - Fee Related
- 2000-07-11 AT AT00943703T patent/ATE265430T1/de not_active IP Right Cessation
- 2000-07-11 NZ NZ516913A patent/NZ516913A/en unknown
- 2000-07-11 DK DK00943703T patent/DK1206448T3/da active
- 2000-07-11 PT PT00943703T patent/PT1206448E/pt unknown
- 2000-07-11 ES ES00943703T patent/ES2216908T3/es not_active Expired - Lifetime
- 2000-07-11 KR KR1020027001539A patent/KR20020022792A/ko not_active Ceased
- 2000-07-11 CN CNB008123454A patent/CN1167678C/zh not_active Expired - Fee Related
- 2000-07-11 CA CA002381910A patent/CA2381910A1/en not_active Abandoned
- 2000-07-11 JP JP2001515296A patent/JP2003506435A/ja active Pending
- 2000-07-11 WO PCT/DK2000/000389 patent/WO2001010829A1/en not_active Ceased
- 2000-07-11 EP EP00943703A patent/EP1206448B1/en not_active Expired - Lifetime
- 2000-07-11 HU HU0202305A patent/HUP0202305A3/hu unknown
- 2000-07-11 PL PL00364698A patent/PL364698A1/xx not_active Application Discontinuation
- 2000-07-11 CZ CZ2002392A patent/CZ2002392A3/cs unknown
- 2000-07-11 HK HK03101142.2A patent/HK1049148B/zh not_active IP Right Cessation
- 2000-07-31 JP JP2001515324A patent/JP4971571B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PL364698A1 (en)	2004-12-13
US6573255B1 (en)	2003-06-03
JP2003506435A (ja)	2003-02-18
CZ2002392A3 (cs)	2002-11-13
WO2001010829A1 (en)	2001-02-15
DE60010276T2 (de)	2005-04-21
AU770771B2 (en)	2004-03-04
DE60010276D1 (de)	2004-06-03
AU5807200A (en)	2001-03-05
PT1206448E (pt)	2004-08-31
ES2216908T3 (es)	2004-11-01
HK1049148A1 (en)	2003-05-02
CN1372544A (zh)	2002-10-02
NZ516913A (en)	2003-11-28
EP1206448B1 (en)	2004-04-28
RU2228928C2 (ru)	2004-05-20
JP4971571B2 (ja)	2012-07-11
EP1206448A1 (en)	2002-05-22
HUP0202305A3 (en)	2003-10-28
HUP0202305A2 (en)	2002-10-28
KR20020022792A (ko)	2002-03-27
CN1167678C (zh)	2004-09-22
CA2381910A1 (en)	2001-02-15
ATE265430T1 (de)	2004-05-15
HK1049148B (zh)	2005-03-11
JP2003506067A (ja)	2003-02-18

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DK0984778T3 (da)	2002-09-16	Neuropeptid-Y-ligander
DK0639186T3 (da)	1999-12-13	Taxolderivater
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RU2008132204A (ru)	2010-02-10	Соединения для лечения метаболических заболеваний
DE60040142D1 (de)	2008-10-16	Pyridin-imin polymerisationskatalysator
CY1113054T1 (el)	2016-04-13	Παραγωγα διαμινης
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IL120266A0 (en)	1997-06-10	Use of estrogen antagonists and estrogen agonists in inhibiting pathological conditions
ES2177058T3 (es)	2002-12-01	Compuestos eter piperidinilaminometil trifluorometil ciclicos como antagonistas de la sustancia p.
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DE69724646D1 (de)	2003-10-09	16-ene-vitamin d derivate
FI942457A0 (fi)	1994-05-26	Substituoitujen piperidiinien valmistus
AR004965A1 (es)	1999-04-07	Procedimiento de preparacion de derivados de fenilimidazolidina
PT1206448E (pt)	2004-08-31	Novos analogos de vitamina d
EA200000628A1 (ru)	2001-02-26	Ингибиторы металлопротеаз матрикса
TR200100740T2 (tr)	2001-10-22	Tiyazolilsinnamonitriller ve haşere kontrol edici ajanlar
AP2001002045A0 (en)	2001-03-31	FKBP inhibitors.
ATE393807T1 (de)	2008-05-15	Alkylbernsteinsäurehydrazid-additive für schmiermittel
ATE201412T1 (de)	2001-06-15	Pteridinderivate als no synthase-hemmer
ES8801669A1 (es)	1988-02-16	Un procedimiento para preparar nuevos compuestos de 2-oxa-0 aza-pregnano.
MY133146A (en)	2007-10-31	Ester compounds
ES8507525A1 (es)	1985-09-01	Procedimiento para preparar 3-acil-2-nitrometilentetrahidro-2h-1, 3-tiazinas
ES2145899T3 (es)	2000-07-16	Derivados de feniltio-oxazolina.