DK1209151T3 - 4-substituerede piperidinderivativer - Google Patents
4-substituerede piperidinderivativerInfo
- Publication number
- DK1209151T3 DK1209151T3 DK00956885T DK00956885T DK1209151T3 DK 1209151 T3 DK1209151 T3 DK 1209151T3 DK 00956885 T DK00956885 T DK 00956885T DK 00956885 T DK00956885 T DK 00956885T DK 1209151 T3 DK1209151 T3 DK 1209151T3
- Authority
- DK
- Denmark
- Prior art keywords
- ingrediates
- piperide
- substituted
- provides
- hydrates
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000012440 Acetylcholinesterase Human genes 0.000 abstract 1
- 108010022752 Acetylcholinesterase Proteins 0.000 abstract 1
- 229940022698 acetylcholinesterase Drugs 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24711599 | 1999-09-01 | ||
| PCT/JP2000/005968 WO2001016105A1 (en) | 1999-09-01 | 2000-09-01 | 4-substituted piperidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1209151T3 true DK1209151T3 (da) | 2007-08-20 |
Family
ID=17158668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00956885T DK1209151T3 (da) | 1999-09-01 | 2000-09-01 | 4-substituerede piperidinderivativer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7091218B1 (de) |
| EP (1) | EP1209151B1 (de) |
| AT (1) | ATE360612T1 (de) |
| CA (1) | CA2382117C (de) |
| CY (1) | CY1106716T1 (de) |
| DE (1) | DE60034577T2 (de) |
| DK (1) | DK1209151T3 (de) |
| ES (1) | ES2284519T3 (de) |
| PT (1) | PT1209151E (de) |
| WO (1) | WO2001016105A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002002526A1 (fr) * | 2000-07-03 | 2002-01-10 | Eisai Co., Ltd. | Compositions pharmaceutiques servant a stabiliser la tension intraoculaire |
| KR100579813B1 (ko) * | 2001-10-16 | 2006-05-12 | 주식회사 에스티씨나라 | 피페리딘 유도체, 이의 제조방법 및 이를 포함하는 치매치료용 약학적 조성물 |
| JP3878178B2 (ja) | 2001-12-28 | 2007-02-07 | 武田薬品工業株式会社 | 排尿障害予防治療剤 |
| EP1468684A4 (de) * | 2002-01-22 | 2008-02-27 | Eisai R&D Man Co Ltd | Sigma-rezeptor-bindungsmolekül mit indanonderivat |
| HUP0401850A3 (en) * | 2004-09-15 | 2008-03-28 | Egis Gyogyszergyar Nyilvanosan | Donepezil salts for producing pharmaceutical composition |
| DE102004046497A1 (de) * | 2004-09-23 | 2006-04-06 | Helm Ag | Donepezil-Salze |
| EP2114166A4 (de) | 2006-12-11 | 2011-05-25 | Reviva Pharmaceuticals Inc | Zusammensetzungen, synthese und verfahren zur verwendung indanonbasierter cholinesterase-hemmer |
| WO2014008629A1 (en) * | 2012-07-10 | 2014-01-16 | Suzhou Shangzhi Biotech Limited | Novel derivatives of donepezil |
| CN103787954B (zh) * | 2012-10-26 | 2016-01-20 | 中国科学院上海药物研究所 | 一类氟取代的环状胺类化合物及其制备方法、药物组合物和用途 |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| EP2968220B1 (de) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| NZ738682A (en) | 2015-05-22 | 2022-01-28 | Agenebio Inc | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000319257A (ja) | 1969-01-06 | 2000-11-21 | Eisai Co Ltd | １−ベンジル−４−［（５，６−ジメトキシ−２−フルオロ−１−インダノン）−２−イル］メチルピペリジン |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| ES2188584T3 (es) | 1991-03-28 | 2003-07-01 | Eisai Co Ltd | Derivados heterociclicos de amina. |
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| CA2116117A1 (en) * | 1991-08-22 | 1993-03-04 | Hiroyuki Sueoka | Benzisoxazole compound and use thereof |
| JPH09268176A (ja) | 1996-04-01 | 1997-10-14 | Eisai Co Ltd | アラルキルピペリジン誘導体 |
| EP1604653A1 (de) | 1998-09-30 | 2005-12-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase-Inhibitoren zur Verbesserung der Ausscheidungskraft der Harnblase |
| US20020177593A1 (en) | 1998-09-30 | 2002-11-28 | Yuji Ishihara | Agents and crystals for improving excretory potency of urinary bladder |
| KR100694682B1 (ko) | 1999-03-03 | 2007-03-13 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 4-치환 피페리딘 유도체 불화물 |
| US6277866B1 (en) | 1999-03-03 | 2001-08-21 | Eisai Co., Ltd. | 1-benzyl-4[(5,6-dimethoxy-2-fluoro-1-indanon)-2-yl]methylpiperidine |
| WO2000057880A1 (en) | 1999-03-29 | 2000-10-05 | Schering Corporation | Methods and compositions for treating allergic and related disorders using fluorinated descarboethoxyloratadine |
| WO2002002526A1 (fr) | 2000-07-03 | 2002-01-10 | Eisai Co., Ltd. | Compositions pharmaceutiques servant a stabiliser la tension intraoculaire |
| IL150982A (en) * | 2002-07-30 | 2007-02-11 | Ori Lerman | Process for making Donafzil |
-
2000
- 2000-09-01 DK DK00956885T patent/DK1209151T3/da active
- 2000-09-01 AT AT00956885T patent/ATE360612T1/de active
- 2000-09-01 PT PT00956885T patent/PT1209151E/pt unknown
- 2000-09-01 DE DE60034577T patent/DE60034577T2/de not_active Expired - Lifetime
- 2000-09-01 CA CA002382117A patent/CA2382117C/en not_active Expired - Fee Related
- 2000-09-01 US US10/069,073 patent/US7091218B1/en not_active Expired - Fee Related
- 2000-09-01 EP EP00956885A patent/EP1209151B1/de not_active Expired - Lifetime
- 2000-09-01 ES ES00956885T patent/ES2284519T3/es not_active Expired - Lifetime
- 2000-09-01 WO PCT/JP2000/005968 patent/WO2001016105A1/ja not_active Ceased
-
2007
- 2007-07-10 CY CY20071100915T patent/CY1106716T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1209151B1 (de) | 2007-04-25 |
| EP1209151A4 (de) | 2004-12-29 |
| CY1106716T1 (el) | 2012-05-23 |
| ATE360612T1 (de) | 2007-05-15 |
| DE60034577T2 (de) | 2007-12-27 |
| US7091218B1 (en) | 2006-08-15 |
| WO2001016105A1 (en) | 2001-03-08 |
| EP1209151A1 (de) | 2002-05-29 |
| DE60034577D1 (de) | 2007-06-06 |
| PT1209151E (pt) | 2007-05-31 |
| ES2284519T3 (es) | 2007-11-16 |
| CA2382117A1 (en) | 2001-03-08 |
| CA2382117C (en) | 2009-11-10 |
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