DK1210430T3 - MUC-1-afledte peptider - Google Patents
MUC-1-afledte peptiderInfo
- Publication number
- DK1210430T3 DK1210430T3 DK00965943T DK00965943T DK1210430T3 DK 1210430 T3 DK1210430 T3 DK 1210430T3 DK 00965943 T DK00965943 T DK 00965943T DK 00965943 T DK00965943 T DK 00965943T DK 1210430 T3 DK1210430 T3 DK 1210430T3
- Authority
- DK
- Denmark
- Prior art keywords
- muc
- polypeptides
- peptides
- derived peptides
- derived
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 9
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 9
- 102100034256 Mucin-1 Human genes 0.000 title abstract 3
- 108010008707 Mucin-1 Proteins 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9921242.5A GB9921242D0 (en) | 1999-09-08 | 1999-09-08 | Cancer vaccine and diagnosis |
| EP99402237 | 1999-09-10 | ||
| US18721500P | 2000-03-03 | 2000-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1210430T3 true DK1210430T3 (da) | 2006-11-20 |
Family
ID=27240232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00965943T DK1210430T3 (da) | 1999-09-08 | 2000-09-07 | MUC-1-afledte peptider |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20050142640A1 (fr) |
| EP (1) | EP1210430B1 (fr) |
| JP (1) | JP2003510094A (fr) |
| AT (1) | ATE338121T1 (fr) |
| AU (1) | AU778701B2 (fr) |
| CA (1) | CA2383737C (fr) |
| DE (1) | DE60030450T2 (fr) |
| DK (1) | DK1210430T3 (fr) |
| ES (1) | ES2270870T3 (fr) |
| PT (1) | PT1210430E (fr) |
| WO (1) | WO2001018035A2 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090004212A1 (en) * | 1997-12-30 | 2009-01-01 | Franz-Georg Hanisch | Tumour vaccines for MUC1-positive carcinomas |
| JP2003533181A (ja) * | 2000-02-01 | 2003-11-11 | ジ・オースティン・リサーチ・インスティテュート | ムチン−1誘導抗原および免疫療法におけるその使用 |
| EP1531842A4 (fr) | 2000-12-22 | 2007-03-07 | Dana Farber Cancer Inst Inc | Regulation de la proliferation cellulaire par muc1 |
| JP2004533421A (ja) | 2001-03-27 | 2004-11-04 | バイオミラ,インコーポレイテッド | T1免疫応答とt2免疫応答との間で調節するためのワクチン |
| CN101024842A (zh) | 2001-11-07 | 2007-08-29 | 曼康公司 | 编码靶相关抗原表位的表达载体及其设计方法 |
| WO2003089451A2 (fr) * | 2002-04-22 | 2003-10-30 | Dyax Corporation | Anticorps specifiques du polypeptide de mucine |
| GB0212046D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0304634D0 (en) * | 2003-02-28 | 2003-04-02 | Glaxo Group Ltd | Vaccines |
| US7696306B2 (en) | 2003-07-11 | 2010-04-13 | Board of Agents of the University of Nebraska | Compositions and methods for preventing or treating cancer |
| GB0321614D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Vaccines |
| WO2005042573A1 (fr) | 2003-10-24 | 2005-05-12 | Dana-Farber Cancer Institute, Inc. | Modulation de l'interaction de muc1 avec des ligands de muc1 |
| EP1697399B1 (fr) * | 2003-12-12 | 2016-11-23 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS | Epitope de lymphocyte t cytotoxique humain et son epitope agoniste issus du nombre non variable de sequences repetees en tandem de muc-1 |
| TWI395591B (zh) | 2004-04-01 | 2013-05-11 | Oncothyreon Inc | 黏液性糖蛋白(muc-1)疫苗 |
| US8871250B2 (en) | 2005-06-28 | 2014-10-28 | Oncothyreon Inc. | Method of treating patients with a mucinous glycoprotein (MUC-1) vaccine |
| US20090317414A1 (en) * | 2006-07-25 | 2009-12-24 | 4G Vaccines Pty Ltd | Cancer vaccine comprising a mucin 1 (muc1) t cell epitope-derived peptide |
| WO2008035350A1 (fr) * | 2006-09-21 | 2008-03-27 | Vaxil Biotherapeutics Ltd. | Vaccins à multiples épitopes spécifiques à un antigène |
| WO2008097844A2 (fr) | 2007-02-02 | 2008-08-14 | Dana -Farber Cancer Institute, Inc. | Méthodes et compositions associées à la régulation de l'apoptose par des protéines muc1 et des protéines pro-apoptotiques contenant seulement le domaine bh3 |
| US7972870B2 (en) | 2007-02-02 | 2011-07-05 | Dana-Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3 |
| WO2009108807A1 (fr) * | 2008-02-26 | 2009-09-03 | The Regents Of The University Of California | Glycopeptides et procédés pour les préparer et les utiliser |
| US8524669B2 (en) | 2008-10-17 | 2013-09-03 | Dana-Farber Cancer Institute, Inc. | MUC-1 cytoplasmic domain peptides as inhibitors of cancer |
| AU2010253834B2 (en) * | 2009-05-27 | 2013-12-19 | Dana-Farber Cancer Institute, Inc. | Inhibition 0f inflammation using antagonists of MUC1 |
| WO2011100688A1 (fr) | 2010-02-12 | 2011-08-18 | Dana-Farber Cancer Institute, Inc. | Antagonistes améliorés du muc1 |
| EP2374470A1 (fr) | 2010-04-08 | 2011-10-12 | Beta Innov | Utilisation thérapeutique de la protéine Beta2m |
| BR112012028893A2 (pt) | 2010-05-10 | 2017-12-12 | Ascend Biopharmaceuticals Pty Ltd | composições imunoestimuladoras e de vacina |
| EP2678005A4 (fr) | 2011-02-24 | 2015-06-10 | Oncothyreon Inc | Vaccin glycolipopeptidique à base de muc1 comportant un adjuvant |
| SG10201607663YA (en) | 2011-08-17 | 2016-11-29 | Globeimmune Inc | Yeast-muc1 immunotherapeutic compositions and uses thereof |
| EP2800762B1 (fr) * | 2012-01-03 | 2018-01-03 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Épitopes de ctl endogènes et agonistes de l'antigène tumoral muc1 |
| US9044421B2 (en) | 2012-03-28 | 2015-06-02 | Genus Oncology, Llc | Treating MUC1-expressing cancers with combination therapies |
| EP3269726B1 (fr) * | 2015-03-09 | 2025-05-07 | Nec Corporation | Peptide dérivé de muc1, composition pharmaceutique pour le traitement ou la prévention du cancer à l'aide de celui-ci, inducteur de la réponse immunitaire, et procédé de production de cellules présentatrices d'antigènes |
| WO2018187515A1 (fr) | 2017-04-04 | 2018-10-11 | Avidea Technologies, Inc. | Vaccins à base de peptides, procédés de fabrication et utilisations de ceux-ci pour induire une réponse immunitaire |
| EP3903811A1 (fr) * | 2020-05-01 | 2021-11-03 | R.G.C.C. Holdings AG | Composition pharmaceutique et procédé pour induire une réponse immunitaire |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| CA2003211A1 (fr) * | 1988-11-17 | 1990-05-17 | Pei-Xiang Xing | Anticorps monoclonaux |
| FR2668064B1 (fr) * | 1990-10-23 | 1994-12-16 | Transgene Sa | Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne. |
| ES2139012T3 (es) * | 1992-05-26 | 2000-02-01 | Univ Leiden | Peptidos de la proteina p53 humana destinados para ser utilizados en composiciones que inducen una reaccion en los linfocitos t humanos, y linfocitos t citotoxicos especificos de la proteina p53 humana. |
| IL110464A0 (en) | 1994-07-26 | 1994-10-21 | Univ Ramot | Novel proteins for the diagnosis, imaging, and therapy of human cancer |
| US6548643B1 (en) * | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
| US6024965A (en) | 1996-10-18 | 2000-02-15 | Erasums University Rotterdam | Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection |
| CA2289742C (fr) * | 1997-05-08 | 2013-07-16 | Biomira Inc. | Procede de generation de cellules t activees et de cellules de presentation d'antigene et a impulsion antigenique |
| JP2002505318A (ja) * | 1998-03-05 | 2002-02-19 | アゴーロン・ファーマシューティカルズ・インコーポレイテッド | 非ペプチドGnRH因子 |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
-
2000
- 2000-09-07 CA CA2383737A patent/CA2383737C/fr not_active Expired - Fee Related
- 2000-09-07 EP EP00965943A patent/EP1210430B1/fr not_active Expired - Lifetime
- 2000-09-07 WO PCT/EP2000/008761 patent/WO2001018035A2/fr not_active Ceased
- 2000-09-07 AU AU76515/00A patent/AU778701B2/en not_active Ceased
- 2000-09-07 ES ES00965943T patent/ES2270870T3/es not_active Expired - Lifetime
- 2000-09-07 PT PT00965943T patent/PT1210430E/pt unknown
- 2000-09-07 DK DK00965943T patent/DK1210430T3/da active
- 2000-09-07 JP JP2001527622A patent/JP2003510094A/ja active Pending
- 2000-09-07 AT AT00965943T patent/ATE338121T1/de active
- 2000-09-07 DE DE60030450T patent/DE60030450T2/de not_active Expired - Lifetime
-
2005
- 2005-02-11 US US11/055,119 patent/US20050142640A1/en not_active Abandoned
-
2008
- 2008-03-04 US US12/042,196 patent/US20080227082A1/en not_active Abandoned
-
2009
- 2009-10-13 US US12/578,499 patent/US7892828B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001018035A3 (fr) | 2001-11-08 |
| WO2001018035A9 (fr) | 2002-09-06 |
| US20050142640A1 (en) | 2005-06-30 |
| AU7651500A (en) | 2001-04-10 |
| EP1210430A2 (fr) | 2002-06-05 |
| DE60030450T2 (de) | 2007-08-30 |
| DE60030450D1 (de) | 2006-10-12 |
| CA2383737C (fr) | 2011-01-18 |
| US7892828B2 (en) | 2011-02-22 |
| ES2270870T3 (es) | 2007-04-16 |
| US20080227082A1 (en) | 2008-09-18 |
| US20100255501A1 (en) | 2010-10-07 |
| PT1210430E (pt) | 2006-12-29 |
| ATE338121T1 (de) | 2006-09-15 |
| WO2001018035A2 (fr) | 2001-03-15 |
| JP2003510094A (ja) | 2003-03-18 |
| CA2383737A1 (fr) | 2001-03-15 |
| EP1210430B1 (fr) | 2006-08-30 |
| AU778701B2 (en) | 2004-12-16 |
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