DK1221969T3 - Aktivering af antigen-specifikke T-celler med virus/antigen-behandlede dendritiske celler - Google Patents
Aktivering af antigen-specifikke T-celler med virus/antigen-behandlede dendritiske cellerInfo
- Publication number
- DK1221969T3 DK1221969T3 DK00969488.6T DK00969488T DK1221969T3 DK 1221969 T3 DK1221969 T3 DK 1221969T3 DK 00969488 T DK00969488 T DK 00969488T DK 1221969 T3 DK1221969 T3 DK 1221969T3
- Authority
- DK
- Denmark
- Prior art keywords
- antigen
- cells
- activation
- specific
- virus
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 210000004443 dendritic cell Anatomy 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000004913 activation Effects 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/34—Antigenic peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/49—Breast
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99119980A EP1092439A1 (en) | 1999-10-13 | 1999-10-13 | Activation of antigen-specific T cells by virus/antigen-treated dendritic cells |
| PCT/EP2000/010019 WO2001026680A2 (en) | 1999-10-13 | 2000-10-11 | Activation of antigen-specific t cells by virus/antigen-treated dendritic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1221969T3 true DK1221969T3 (da) | 2010-08-02 |
Family
ID=8239146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00969488.6T DK1221969T3 (da) | 1999-10-13 | 2000-10-11 | Aktivering af antigen-specifikke T-celler med virus/antigen-behandlede dendritiske celler |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090060946A1 (da) |
| EP (2) | EP1092439A1 (da) |
| JP (1) | JP2003511419A (da) |
| AT (1) | ATE464064T1 (da) |
| AU (1) | AU782196B2 (da) |
| CA (1) | CA2387063A1 (da) |
| DE (1) | DE60044198D1 (da) |
| DK (1) | DK1221969T3 (da) |
| ES (1) | ES2343673T3 (da) |
| WO (1) | WO2001026680A2 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1092439A1 (en) * | 1999-10-13 | 2001-04-18 | Thorsten Dr. Ahlert | Activation of antigen-specific T cells by virus/antigen-treated dendritic cells |
| CN111655280B (zh) * | 2017-09-01 | 2025-01-14 | 达纳-法伯癌症研究所股份有限公司 | 用于治疗癌症的bcma和taci抗原特异的免疫原性肽 |
| US12448429B2 (en) | 2019-03-06 | 2025-10-21 | Dana-Farber Cancer Institute, Inc. | T cell receptors specific to b-cell maturation antigen for treatment of cancer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3806565A1 (de) * | 1988-03-01 | 1989-09-14 | Deutsches Krebsforsch | Virusmodifizierte tumorvakzinen fuer die immuntherapie von tumormetastasen |
| KR960701208A (ko) * | 1993-03-16 | 1996-02-24 | 엔 엔 데이비스 | 바이러스 단백질에 의해 면역 반응을 자극하는 방법(stimulation of immune response by viral protein) |
| DE4407538C1 (de) * | 1994-03-07 | 1995-02-23 | Deutsches Krebsforsch | Bindungsreagens für Zell-Oberflächenprotein und Effektorzelle |
| EP1092439A1 (en) * | 1999-10-13 | 2001-04-18 | Thorsten Dr. Ahlert | Activation of antigen-specific T cells by virus/antigen-treated dendritic cells |
-
1999
- 1999-10-13 EP EP99119980A patent/EP1092439A1/en not_active Withdrawn
-
2000
- 2000-10-11 WO PCT/EP2000/010019 patent/WO2001026680A2/en not_active Ceased
- 2000-10-11 EP EP00969488A patent/EP1221969B1/en not_active Expired - Lifetime
- 2000-10-11 ES ES00969488T patent/ES2343673T3/es not_active Expired - Lifetime
- 2000-10-11 DE DE60044198T patent/DE60044198D1/de not_active Expired - Lifetime
- 2000-10-11 CA CA002387063A patent/CA2387063A1/en not_active Abandoned
- 2000-10-11 AT AT00969488T patent/ATE464064T1/de active
- 2000-10-11 AU AU79184/00A patent/AU782196B2/en not_active Ceased
- 2000-10-11 JP JP2001529741A patent/JP2003511419A/ja active Pending
- 2000-10-11 DK DK00969488.6T patent/DK1221969T3/da active
-
2008
- 2008-10-21 US US12/288,553 patent/US20090060946A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090060946A1 (en) | 2009-03-05 |
| DE60044198D1 (de) | 2010-05-27 |
| ES2343673T3 (es) | 2010-08-06 |
| JP2003511419A (ja) | 2003-03-25 |
| EP1221969A2 (en) | 2002-07-17 |
| AU782196B2 (en) | 2005-07-07 |
| WO2001026680A2 (en) | 2001-04-19 |
| ATE464064T1 (de) | 2010-04-15 |
| EP1221969B1 (en) | 2010-04-14 |
| AU7918400A (en) | 2001-04-23 |
| EP1092439A1 (en) | 2001-04-18 |
| CA2387063A1 (en) | 2001-04-19 |
| WO2001026680A3 (en) | 2001-11-08 |
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