BRPI0414381A - composição de adjuvante, composição ou composições imunogênica(s), composição de vacina, processo para a fabricação de uma composição imunogênica, composição ou composições farmacêutica(s), kit, métodos para tratar um paciente que sofre de, ou que é suscetìvel a, um tumor, para incrementar uma resposta imune de um mamìfero a um antìgeno e para suscitar uma resposta imune em m mamìfero contra um estado de doença, usos de uma imidazoquinolina ou derivado da mesma e gm-csf e dos componentes - Google Patents

composição de adjuvante, composição ou composições imunogênica(s), composição de vacina, processo para a fabricação de uma composição imunogênica, composição ou composições farmacêutica(s), kit, métodos para tratar um paciente que sofre de, ou que é suscetìvel a, um tumor, para incrementar uma resposta imune de um mamìfero a um antìgeno e para suscitar uma resposta imune em m mamìfero contra um estado de doença, usos de uma imidazoquinolina ou derivado da mesma e gm-csf e dos componentes

Info

Publication number
BRPI0414381A
BRPI0414381A BRPI0414381-7A BRPI0414381A BRPI0414381A BR PI0414381 A BRPI0414381 A BR PI0414381A BR PI0414381 A BRPI0414381 A BR PI0414381A BR PI0414381 A BRPI0414381 A BR PI0414381A
Authority
BR
Brazil
Prior art keywords
composition
immune response
mammalian immune
immunogenic composition
csf
Prior art date
Application number
BRPI0414381-7A
Other languages
English (en)
Inventor
Gary Pater Bembridge
Jennifer L Craigen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BRPI0414381A publication Critical patent/BRPI0414381A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"COMPOSIçãO DE ADJUVANTE, COMPOSIçãO OU COMPOSIçõES IMUNOGêNICA(S), COMPOSIçãO DE VACINA, PROCESSO PARA A FABRICAçãO DE UMA COMPOSIçãO IMUNOGêNICA, COMPOSIçãO OU COMPOSIçõES FARMACêUTICA(S), KIT, MéTODOS PARA TRATAR UM PACIENTE QUE SOFRE DE, OU QUE é SUSCETìVEL A, UM TUMOR, PARA INCREMENTAR UMA RESPOSTA IMUNE DE UM MAMìFERO A UM ANTìGENO E PARA SUSCITAR UMA RESPOSTA IMUNE EM UM MAMìFERO CONTRA UM ESTADO DE DOENçA, USOS DE UMA IMIDAZOQUINOLINA OU DERIVADO DA MESMA E GM-CSF E DOS COMPONENTES". A presente invenção refere-se a vacinas de ácido nucleico aperfeiçoadas, sistemas adjuvantes, e processos para a preparação de referidas vacinas e sistemas adjuvantes. Em particular, as vacinas de ácido nucleico e sistemas adjuvantes da presente invenção compreendem uma combinação de uma seqüência de nucleotídeos codificando GM-CSF, ou derivados dos mesmos, e agonistas de receptor tipo Toll (TLR), ou derivados dos mesmos.
BRPI0414381-7A 2003-09-15 2004-09-13 composição de adjuvante, composição ou composições imunogênica(s), composição de vacina, processo para a fabricação de uma composição imunogênica, composição ou composições farmacêutica(s), kit, métodos para tratar um paciente que sofre de, ou que é suscetìvel a, um tumor, para incrementar uma resposta imune de um mamìfero a um antìgeno e para suscitar uma resposta imune em m mamìfero contra um estado de doença, usos de uma imidazoquinolina ou derivado da mesma e gm-csf e dos componentes BRPI0414381A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0321615.7A GB0321615D0 (en) 2003-09-15 2003-09-15 Improvements in vaccination
PCT/EP2004/010322 WO2005025614A2 (en) 2003-09-15 2004-09-13 Improvements in vaccination

Publications (1)

Publication Number Publication Date
BRPI0414381A true BRPI0414381A (pt) 2006-11-21

Family

ID=29227139

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414381-7A BRPI0414381A (pt) 2003-09-15 2004-09-13 composição de adjuvante, composição ou composições imunogênica(s), composição de vacina, processo para a fabricação de uma composição imunogênica, composição ou composições farmacêutica(s), kit, métodos para tratar um paciente que sofre de, ou que é suscetìvel a, um tumor, para incrementar uma resposta imune de um mamìfero a um antìgeno e para suscitar uma resposta imune em m mamìfero contra um estado de doença, usos de uma imidazoquinolina ou derivado da mesma e gm-csf e dos componentes

Country Status (19)

Country Link
US (1) US20080145375A1 (pt)
EP (1) EP1682175A2 (pt)
JP (1) JP2007505827A (pt)
KR (1) KR20070029111A (pt)
CN (1) CN1878567A (pt)
AU (1) AU2004271726A1 (pt)
BR (1) BRPI0414381A (pt)
CA (1) CA2538197A1 (pt)
GB (1) GB0321615D0 (pt)
IL (1) IL174131A0 (pt)
IS (1) IS8363A (pt)
MA (1) MA28323A1 (pt)
MX (1) MXPA06002969A (pt)
NO (1) NO20061242L (pt)
NZ (1) NZ545948A (pt)
RU (1) RU2370537C2 (pt)
SG (1) SG145767A1 (pt)
WO (1) WO2005025614A2 (pt)
ZA (1) ZA200602156B (pt)

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