DK1224164T3 - Hydroxaminsyrederivat som inhibitor for produktion af oplöselig human CD23 - Google Patents

Hydroxaminsyrederivat som inhibitor for produktion af oplöselig human CD23

Info

Publication number: DK1224164T3
Authority: DK; Denmark
Prior art keywords: inhibitor; production; acid derivative; hydroxamic acid; soluble human
Prior art date: 1999-10-27

Application number

DK00975954T

Other languages

English (en)

Inventor

Andrew Faller

John Gerard Ward

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-27

Filing date

2000-10-25

Publication date

2005-03-29

2000-10-25 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2005-03-29 Application granted granted Critical

2005-03-29 Publication of DK1224164T3 publication Critical patent/DK1224164T3/da

Links

NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
101000878605 Homo sapiens Low affinity immunoglobulin epsilon Fc receptor Proteins 0.000 title 1
102100038007 Low affinity immunoglobulin epsilon Fc receptor Human genes 0.000 title 1
239000002253 acid Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

DK00975954T 1999-10-27 2000-10-25 Hydroxaminsyrederivat som inhibitor for produktion af oplöselig human CD23 DK1224164T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9925470.8A GB9925470D0 (en)	1999-10-27	1999-10-27	Novel compounds
PCT/EP2000/010649 WO2001030747A1 (en)	1999-10-27	2000-10-25	Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23
EP00975954A EP1224164B1 (en)	1999-10-27	2000-10-25	Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Publications (1)

Publication Number	Publication Date
DK1224164T3 true DK1224164T3 (da)	2005-03-29

Family

ID=10863507

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00975954T DK1224164T3 (da)	1999-10-27	2000-10-25	Hydroxaminsyrederivat som inhibitor for produktion af oplöselig human CD23

Country Status (31)

Country	Link
US (2)	US6673965B1 (da)
EP (1)	EP1224164B1 (da)
JP (1)	JP3922431B2 (da)
KR (1)	KR20020044578A (da)
CN (1)	CN1182107C (da)
AR (1)	AR026244A1 (da)
AT (1)	ATE284382T1 (da)
AU (1)	AU766072B2 (da)
BR (1)	BR0015082A (da)
CA (1)	CA2389319A1 (da)
CO (1)	CO5261576A1 (da)
CZ (1)	CZ20021424A3 (da)
DE (1)	DE60016622T2 (da)
DK (1)	DK1224164T3 (da)
ES (1)	ES2233474T3 (da)
GB (1)	GB9925470D0 (da)
GC (1)	GC0000142A (da)
HU (1)	HUP0203270A3 (da)
IL (1)	IL149364A0 (da)
MX (1)	MXPA02004228A (da)
MY (1)	MY133601A (da)
NO (1)	NO20021965L (da)
NZ (1)	NZ518566A (da)
PE (1)	PE20010898A1 (da)
PL (1)	PL356524A1 (da)
PT (1)	PT1224164E (da)
SI (1)	SI1224164T1 (da)
TW (1)	TW561141B (da)
UY (1)	UY26416A1 (da)
WO (1)	WO2001030747A1 (da)
ZA (1)	ZA200203255B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010032147A2 (en) *	2008-09-19	2010-03-25	Pfizer Inc.	Hydroxamic acid derivatives useful as antibacterial agents
WO2011068853A2 (en)	2009-12-01	2011-06-09	Boston Medical Center Corporation	TREATMENT OF IgE-MEDIATED DISEASE
DK2512474T3 (da)	2009-12-16	2014-12-01	Pfizer	N-forbundne hydroxaminsyrederivativer, der kan anvendes som antibakterielle midler
MA34963B1 (fr)	2011-03-07	2014-03-01	Pfizer	Derives de fluoro-pyridinone utiles en tant qu'agents antibacteriens
CA2830866A1 (en)	2011-04-08	2012-10-11	Pfizer Inc.	Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
WO2012137094A1 (en)	2011-04-08	2012-10-11	Pfizer Inc.	Isoxazole derivatives useful as antibacterial agents
EP2525213A1 (en) *	2011-05-16	2012-11-21	Renishaw plc	Spectroscopic apparatus and methods for determining components present in a sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9513331D0 (en) *	1995-06-30	1995-09-06	British Biotech Pharm	Matrix metalloproteinase inhibitors
GB9813451D0 (en) *	1998-06-22	1998-08-19	Smithkline Beecham Plc	Novel compounds

1999
- 1999-10-27 GB GBGB9925470.8A patent/GB9925470D0/en not_active Ceased
2000
- 2000-10-25 BR BR0015082-7A patent/BR0015082A/pt not_active IP Right Cessation
- 2000-10-25 CA CA002389319A patent/CA2389319A1/en not_active Abandoned
- 2000-10-25 AT AT00975954T patent/ATE284382T1/de not_active IP Right Cessation
- 2000-10-25 MX MXPA02004228A patent/MXPA02004228A/es active IP Right Grant
- 2000-10-25 JP JP2001533102A patent/JP3922431B2/ja not_active Expired - Fee Related
- 2000-10-25 CZ CZ20021424A patent/CZ20021424A3/cs unknown
- 2000-10-25 UY UY26416A patent/UY26416A1/es not_active Application Discontinuation
- 2000-10-25 PL PL00356524A patent/PL356524A1/xx unknown
- 2000-10-25 ES ES00975954T patent/ES2233474T3/es not_active Expired - Lifetime
- 2000-10-25 NZ NZ518566A patent/NZ518566A/en unknown
- 2000-10-25 WO PCT/EP2000/010649 patent/WO2001030747A1/en not_active Ceased
- 2000-10-25 AU AU13895/01A patent/AU766072B2/en not_active Ceased
- 2000-10-25 US US10/111,209 patent/US6673965B1/en not_active Expired - Fee Related
- 2000-10-25 CN CNB008173680A patent/CN1182107C/zh not_active Expired - Fee Related
- 2000-10-25 DE DE60016622T patent/DE60016622T2/de not_active Expired - Lifetime
- 2000-10-25 GC GCP2000972 patent/GC0000142A/xx active
- 2000-10-25 MY MYPI20005012A patent/MY133601A/en unknown
- 2000-10-25 KR KR1020027005340A patent/KR20020044578A/ko not_active Withdrawn
- 2000-10-25 PT PT00975954T patent/PT1224164E/pt unknown
- 2000-10-25 IL IL14936400A patent/IL149364A0/xx unknown
- 2000-10-25 AR ARP000105622A patent/AR026244A1/es not_active Application Discontinuation
- 2000-10-25 DK DK00975954T patent/DK1224164T3/da active
- 2000-10-25 SI SI200030603T patent/SI1224164T1/xx unknown
- 2000-10-25 EP EP00975954A patent/EP1224164B1/en not_active Expired - Lifetime
- 2000-10-25 HU HU0203270A patent/HUP0203270A3/hu unknown
- 2000-10-26 TW TW089122497A patent/TW561141B/zh active
- 2000-10-26 CO CO00081571A patent/CO5261576A1/es not_active Application Discontinuation
- 2000-10-27 PE PE2000001156A patent/PE20010898A1/es not_active Application Discontinuation
2002
- 2002-04-24 ZA ZA200203255A patent/ZA200203255B/en unknown
- 2002-04-25 NO NO20021965A patent/NO20021965L/no unknown
2003
- 2003-10-03 US US10/678,679 patent/US20040077727A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PE20010898A1 (es)	2001-10-13
NO20021965D0 (no)	2002-04-25
KR20020044578A (ko)	2002-06-15
GC0000142A (en)	2005-06-29
NO20021965L (no)	2002-06-13
WO2001030747A1 (en)	2001-05-03
NZ518566A (en)	2004-02-27
HUP0203270A2 (hu)	2003-02-28
US6673965B1 (en)	2004-01-06
PT1224164E (pt)	2005-04-29
DE60016622T2 (de)	2005-11-03
CN1182107C (zh)	2004-12-29
ATE284382T1 (de)	2004-12-15
UY26416A1 (es)	2001-05-31
JP2003512450A (ja)	2003-04-02
IL149364A0 (en)	2002-11-10
AU766072B2 (en)	2003-10-09
ES2233474T3 (es)	2005-06-16
MY133601A (en)	2007-11-30
TW561141B (en)	2003-11-11
EP1224164A1 (en)	2002-07-24
CN1411436A (zh)	2003-04-16
DE60016622D1 (de)	2005-01-13
SI1224164T1 (en)	2005-06-30
GB9925470D0 (en)	1999-12-29
HK1049146A1 (en)	2003-05-02
ZA200203255B (en)	2003-03-20
PL356524A1 (en)	2004-06-28
EP1224164B1 (en)	2004-12-08
CZ20021424A3 (cs)	2002-09-11
AR026244A1 (es)	2003-02-05
US20040077727A1 (en)	2004-04-22
CO5261576A1 (es)	2003-03-31
AU1389501A (en)	2001-05-08
HUP0203270A3 (en)	2003-11-28
JP3922431B2 (ja)	2007-05-30
MXPA02004228A (es)	2002-10-17
BR0015082A (pt)	2003-04-15
CA2389319A1 (en)	2001-05-03

Publication	Publication Date	Title
NO20031784L (no)	2003-04-23	Heteroarylalkylpiperazinderivater som fettsyre- oksydasjonsinhibitorer
NO20010686D0 (no)	2001-02-09	Hydroksypipecolathydroksaminsyrederivater som MMP inhibitorer
NO20030867L (no)	2003-02-25	Hydroksamderivater anvendelig som deacetylaseinhibitorer
CY2009011I2 (el)	2010-07-28	Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
DK1460066T3 (da)	2009-11-02	Piperazinforbindelse som tachykinin-inhibitorer
DE60035631D1 (de)	2007-09-06	Inhibitoren der Interleukin-4 Produktion
NO20022125D0 (no)	2002-05-03	Pyrrolderivater som inhibitorer for fosfodiesterase VII
PL366900A1 (pl)	2005-02-07	Nowe pochodne kwasu sulfonowego
DE60043730D1 (de)	2010-03-11	Arylsulfonamid-substituierte hydroxamsäure-derivate
NO20016201D0 (no)	2001-12-18	Tienopyrimidiner som fosfodiesteraseinhibitorer
NO20021959D0 (no)	2002-04-25	Tetrahydrotiopyranftalazinon-derivater som PDE4-inhibitorer
DE60012303D1 (de)	2004-08-26	Alkinylische hydroxamsäureverbindungen als tace inhibitoren
DK1224164T3 (da)	2005-03-29	Hydroxaminsyrederivat som inhibitor for produktion af oplöselig human CD23
NO20016403L (no)	2002-03-01	Substituerte purinderivater som inhibitorer av celleadhesjon
NO20022123D0 (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
PT1513806E (pt)	2009-05-04	Sais de ácido sulfónico de derivados do ácido mandélico
NO20024481D0 (no)	2002-09-19	Difluorbutyrsyre metalloproteaseinhibitorer
NO20043084L (no)	2004-07-16	3-fenyl-2-arylalkyltiopropionsyre derivater som selektive agnoister av PPAR-ALPHA
DK1089963T3 (da)	2004-10-18	Hydroxamsyrederivater som inhibitorer af produktion af humant CD23 og af TBF-frigivelse
DK1497290T3 (da)	2008-12-15	Fremgangsmåde til fremstilling af syresalte af gemifloxacin
DK1438286T3 (da)	2010-08-16	Fremgangsmåde til fremstilling af arylsulfonsyreisocyanater
ATE297382T1 (de)	2005-06-15	3-heterocyclyl propanohydroxamsäure-derivaten als pcp inhibitoren
AU2000265100A1 (en)	2002-01-21	N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase
EE200100448A (et)	2002-12-16	Bifenüül-2-karboksüülhappe derivaatide valmistamise meetod
NO20022838D0 (no)	2002-06-14	Saccharinderivater som oralt aktive elastaseinhibitorer