ATE284382T1 - Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 - Google Patents

Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Info

Publication number
ATE284382T1
ATE284382T1 AT00975954T AT00975954T ATE284382T1 AT E284382 T1 ATE284382 T1 AT E284382T1 AT 00975954 T AT00975954 T AT 00975954T AT 00975954 T AT00975954 T AT 00975954T AT E284382 T1 ATE284382 T1 AT E284382T1
Authority
AT
Austria
Prior art keywords
inhibitor
production
acid derivative
hydroxamic acid
soluble human
Prior art date
Application number
AT00975954T
Other languages
English (en)
Inventor
Andrew S Faller
John Gerard Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE284382T1 publication Critical patent/ATE284382T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
AT00975954T 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 ATE284382T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9925470.8A GB9925470D0 (en) 1999-10-27 1999-10-27 Novel compounds
PCT/EP2000/010649 WO2001030747A1 (en) 1999-10-27 2000-10-25 Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Publications (1)

Publication Number Publication Date
ATE284382T1 true ATE284382T1 (de) 2004-12-15

Family

ID=10863507

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00975954T ATE284382T1 (de) 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Country Status (31)

Country Link
US (2) US6673965B1 (de)
EP (1) EP1224164B1 (de)
JP (1) JP3922431B2 (de)
KR (1) KR20020044578A (de)
CN (1) CN1182107C (de)
AR (1) AR026244A1 (de)
AT (1) ATE284382T1 (de)
AU (1) AU766072B2 (de)
BR (1) BR0015082A (de)
CA (1) CA2389319A1 (de)
CO (1) CO5261576A1 (de)
CZ (1) CZ20021424A3 (de)
DE (1) DE60016622T2 (de)
DK (1) DK1224164T3 (de)
ES (1) ES2233474T3 (de)
GB (1) GB9925470D0 (de)
GC (1) GC0000142A (de)
HU (1) HUP0203270A3 (de)
IL (1) IL149364A0 (de)
MX (1) MXPA02004228A (de)
MY (1) MY133601A (de)
NO (1) NO20021965L (de)
NZ (1) NZ518566A (de)
PE (1) PE20010898A1 (de)
PL (1) PL356524A1 (de)
PT (1) PT1224164E (de)
SI (1) SI1224164T1 (de)
TW (1) TW561141B (de)
UY (1) UY26416A1 (de)
WO (1) WO2001030747A1 (de)
ZA (1) ZA200203255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5524215B2 (ja) * 2008-09-19 2014-06-18 ファイザー・インク 抗菌剤として有用なヒドロキサム酸誘導体
EP2507266B1 (de) 2009-12-01 2015-02-18 Boston Medical Center Corporation Behandlung von ige-vermittelten erkrankungen
WO2011073845A1 (en) 2009-12-16 2011-06-23 Pfizer Inc. N-linked hydroxamic acid derivatives useful as antibacterial agents
ES2626457T3 (es) 2011-03-07 2017-07-25 Pfizer Inc. Derivados de fluoro-piridinona útiles como agentes antibacterianos
ES2526687T3 (es) 2011-04-08 2015-01-14 Pfizer Inc. Derivados de isoxazol útiles como agentes antibacterianos
CA2830866A1 (en) 2011-04-08 2012-10-11 Pfizer Inc. Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
EP2525213A1 (de) * 2011-05-16 2012-11-21 Renishaw plc Spektroskopievorrichtung und Verfahren zur Bestimmung der in einer Probe vorkommenden Komponenten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513331D0 (en) 1995-06-30 1995-09-06 British Biotech Pharm Matrix metalloproteinase inhibitors
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
EP1224164B1 (de) 2004-12-08
AU1389501A (en) 2001-05-08
HUP0203270A3 (en) 2003-11-28
IL149364A0 (en) 2002-11-10
EP1224164A1 (de) 2002-07-24
HUP0203270A2 (hu) 2003-02-28
MXPA02004228A (es) 2002-10-17
DK1224164T3 (da) 2005-03-29
ES2233474T3 (es) 2005-06-16
CA2389319A1 (en) 2001-05-03
TW561141B (en) 2003-11-11
KR20020044578A (ko) 2002-06-15
MY133601A (en) 2007-11-30
US20040077727A1 (en) 2004-04-22
BR0015082A (pt) 2003-04-15
AU766072B2 (en) 2003-10-09
CN1411436A (zh) 2003-04-16
NO20021965D0 (no) 2002-04-25
CO5261576A1 (es) 2003-03-31
JP3922431B2 (ja) 2007-05-30
AR026244A1 (es) 2003-02-05
SI1224164T1 (en) 2005-06-30
PL356524A1 (en) 2004-06-28
DE60016622D1 (de) 2005-01-13
JP2003512450A (ja) 2003-04-02
PT1224164E (pt) 2005-04-29
CZ20021424A3 (cs) 2002-09-11
HK1049146A1 (en) 2003-05-02
WO2001030747A1 (en) 2001-05-03
ZA200203255B (en) 2003-03-20
NO20021965L (no) 2002-06-13
US6673965B1 (en) 2004-01-06
PE20010898A1 (es) 2001-10-13
DE60016622T2 (de) 2005-11-03
GC0000142A (en) 2005-06-29
UY26416A1 (es) 2001-05-31
CN1182107C (zh) 2004-12-29
NZ518566A (en) 2004-02-27
GB9925470D0 (en) 1999-12-29

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