DK1252155T3 - Ethanolsolvat af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on - Google Patents

Ethanolsolvat af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on

Info

Publication number: DK1252155T3
Authority: DK; Denmark
Prior art keywords: benzopyran; piperidinyl; chlorophenyl; dihydroxy; cis
Prior art date: 2000-01-18

Application number

DK01902993T

Other languages

Danish (da)

English (en)

Inventor

Kurt M Kesseler

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2001-01-08

Publication date

2005-04-04

2001-01-08 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2005-04-04 Application granted granted Critical

2005-04-04 Publication of DK1252155T3 publication Critical patent/DK1252155T3/da

Links

LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 2
125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 title 1
125000003386 piperidinyl group Chemical group 0.000 title 1
239000012453 solvate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

DK01902993T 2000-01-18 2001-01-08 Ethanolsolvat af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on DK1252155T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US48781500A	2000-01-18	2000-01-18
EP01902993A EP1252155B1 (de)	2000-01-18	2001-01-08	Ethanolsolvat von (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8- [4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-on
PCT/US2001/000520 WO2001053294A1 (en)	2000-01-18	2001-01-08	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (1)

Publication Number	Publication Date
DK1252155T3 true DK1252155T3 (da)	2005-04-04

Family

ID=23937213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01902993T DK1252155T3 (da)	2000-01-18	2001-01-08	Ethanolsolvat af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on

Country Status (26)

Country	Link
EP (1)	EP1252155B1 (de)
JP (1)	JP2003520798A (de)
KR (1)	KR100825530B1 (de)
CN (1)	CN1395577A (de)
AR (1)	AR027226A1 (de)
AT (1)	ATE284400T1 (de)
AU (1)	AU2001230869A1 (de)
BR (1)	BR0107724A (de)
CA (1)	CA2397594C (de)
CZ (1)	CZ301235B6 (de)
DE (1)	DE60107652T2 (de)
DK (1)	DK1252155T3 (de)
EA (1)	EA005182B1 (de)
ES (1)	ES2228800T3 (de)
HU (1)	HU225155B1 (de)
IL (2)	IL150643A0 (de)
MX (1)	MXPA02006965A (de)
NO (1)	NO322626B1 (de)
NZ (1)	NZ520281A (de)
PL (1)	PL201690B1 (de)
PT (1)	PT1252155E (de)
SI (1)	SI1252155T1 (de)
SK (1)	SK287216B6 (de)
TW (1)	TWI293072B (de)
WO (1)	WO2001053294A1 (de)
ZA (1)	ZA200205640B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR112019003722A2 (pt)	2016-08-23	2019-05-28	Eisai R&D Man Co Ltd	terapias de combinação para o tratamento de carcinoma hepatocelular
MX2019010981A (es)	2017-03-16	2020-09-07	Eisai R&D Man Co Ltd	Terapias de combinacion para el tratamiento de cancer de mama.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN164232B (de) *	1986-04-11	1989-02-04	Hoechst India
US5284856A (en) *	1988-10-28	1994-02-08	Hoechst Aktiengesellschaft	Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
DE3836676A1 (de) *	1988-10-28	1990-05-03	Hoechst Ag	Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5908934A (en) *	1996-09-26	1999-06-01	Bristol-Myers Squibb Company	Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

2001
- 2001-01-08 IL IL15064301A patent/IL150643A0/xx unknown
- 2001-01-08 AT AT01902993T patent/ATE284400T1/de active
- 2001-01-08 MX MXPA02006965A patent/MXPA02006965A/es active IP Right Grant
- 2001-01-08 SK SK1037-2002A patent/SK287216B6/sk not_active IP Right Cessation
- 2001-01-08 EA EA200200776A patent/EA005182B1/ru not_active IP Right Cessation
- 2001-01-08 CN CN01803857A patent/CN1395577A/zh active Pending
- 2001-01-08 HU HU0204297A patent/HU225155B1/hu not_active IP Right Cessation
- 2001-01-08 PT PT01902993T patent/PT1252155E/pt unknown
- 2001-01-08 KR KR1020027009140A patent/KR100825530B1/ko not_active Expired - Fee Related
- 2001-01-08 WO PCT/US2001/000520 patent/WO2001053294A1/en not_active Ceased
- 2001-01-08 NZ NZ520281A patent/NZ520281A/en not_active IP Right Cessation
- 2001-01-08 CZ CZ20022467A patent/CZ301235B6/cs not_active IP Right Cessation
- 2001-01-08 CA CA2397594A patent/CA2397594C/en not_active Expired - Fee Related
- 2001-01-08 JP JP2001553768A patent/JP2003520798A/ja active Pending
- 2001-01-08 DK DK01902993T patent/DK1252155T3/da active
- 2001-01-08 AU AU2001230869A patent/AU2001230869A1/en not_active Abandoned
- 2001-01-08 EP EP01902993A patent/EP1252155B1/de not_active Expired - Lifetime
- 2001-01-08 ES ES01902993T patent/ES2228800T3/es not_active Expired - Lifetime
- 2001-01-08 PL PL355992A patent/PL201690B1/pl not_active IP Right Cessation
- 2001-01-08 DE DE60107652T patent/DE60107652T2/de not_active Expired - Lifetime
- 2001-01-08 SI SI200130293T patent/SI1252155T1/xx unknown
- 2001-01-08 BR BR0107724-4A patent/BR0107724A/pt not_active Application Discontinuation
- 2001-01-17 AR ARP010100186A patent/AR027226A1/es not_active Application Discontinuation
- 2001-01-17 TW TW090101052A patent/TWI293072B/zh not_active IP Right Cessation
2002
- 2002-07-08 IL IL150643A patent/IL150643A/en not_active IP Right Cessation
- 2002-07-12 NO NO20023385A patent/NO322626B1/no not_active IP Right Cessation
- 2002-07-15 ZA ZA200205640A patent/ZA200205640B/en unknown

Also Published As

Publication number	Publication date
PL355992A1 (en)	2004-05-31
HUP0204297A3 (en)	2005-04-28
DE60107652D1 (de)	2005-01-13
MXPA02006965A (es)	2004-09-06
SK10372002A3 (sk)	2002-12-03
EA005182B1 (ru)	2004-12-30
CZ20022467A3 (cs)	2002-10-16
CA2397594A1 (en)	2001-07-26
CN1395577A (zh)	2003-02-05
KR100825530B1 (ko)	2008-04-25
DE60107652T2 (de)	2005-12-22
TWI293072B (en)	2008-02-01
HU225155B1 (en)	2006-07-28
IL150643A (en)	2009-08-03
JP2003520798A (ja)	2003-07-08
ZA200205640B (en)	2003-11-26
EP1252155B1 (de)	2004-12-08
EA200200776A1 (ru)	2002-12-26
NO20023385L (no)	2002-08-27
CZ301235B6 (cs)	2009-12-16
AU2001230869A1 (en)	2001-07-31
CA2397594C (en)	2010-03-23
NO322626B1 (no)	2006-11-06
HUP0204297A2 (hu)	2003-04-28
PL201690B1 (pl)	2009-04-30
WO2001053294A1 (en)	2001-07-26
ES2228800T3 (es)	2005-04-16
AR027226A1 (es)	2003-03-19
KR20020069514A (ko)	2002-09-04
IL150643A0 (en)	2003-02-12
EP1252155A1 (de)	2002-10-30
SK287216B6 (sk)	2010-03-08
NZ520281A (en)	2004-04-30
BR0107724A (pt)	2002-10-01
SI1252155T1 (en)	2005-06-30
ATE284400T1 (de)	2004-12-15
NO20023385D0 (no)	2002-07-12
PT1252155E (pt)	2005-04-29

Publication	Publication Date	Title
NO20023777D0 (no)	2002-08-09	Rörformet setteverktöy
ATE306928T1 (de)	2005-11-15	Fulvestrant formulierung
NO20023932L (no)	2002-10-24	Nye forbindelser
ATE285209T1 (de)	2005-01-15	Erektionshilfe
NO20032596D0 (no)	2003-06-06	Heterosykliske etersubstituerte imidazokinoliner
CY1104912T1 (el)	2009-11-04	Υποκατεστημενα πυραζολια
ATE333445T1 (de)	2006-08-15	Pyrazolderivate
DE60139571D1 (de)	2009-09-24	Muscarin-antagonisten
ATE308543T1 (de)	2005-11-15	Piperidinderivate
DK1360184T3 (da)	2005-08-01	Piperidinderivater som neurokinin-1-antagonister
DE59910145D1 (de)	2004-09-09	2-(2-chlorphenyl)-3,4-dihydro-2h-pyrrol-derivate
DE60124942D1 (de)	2007-01-11	Bohrlochkern-bohrvorrichtung
ATE414056T1 (de)	2008-11-15	Substituierte c-cyclohexylmethylamin-derivative
DE602004026333D1 (de)	2010-05-12	NEUE KRISTALLINE FORMEN VON ä2-Ä1-(3,5-BISTRIFLUORMETHYLBENZYL)-5-PYRIDIN-4-YL-1H-Ä1,2,3ÜÜTRIAZOL-4-YLÜ-PYRIDIN-3-YLü-(2-CHLORPHENYL)METHANON
ATE282021T1 (de)	2004-11-15	Substituierte aminomethyl-phenyl- cyclohexanderivate
DK1252155T3 (da)	2005-04-04	Ethanolsolvat af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8-[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on
DE60110046D1 (de)	2005-05-19	Cyclische hexapeptidderivate
IT1316994B1 (it)	2003-05-26	Uso di benzoderivati di piperidina come fungicidi.
DK1259507T3 (da)	2004-11-01	Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid
DE60139781D1 (de)	2009-10-15	4-substituierte piperidinverbindung
DE50112454D1 (de)	2007-06-14	Substituierte 5-amino-1-penten-3-ol-derivate
DE60217632D1 (de)	2007-03-08	Wandnachbildungen
NO20013294L (no)	2002-01-07	Dusjskillevegg
EE04180B1 (et)	2003-12-15	Ruunharmonisaator
ATA3572000A (de)	2002-02-15	Bohrer