DK127487A - Substituerede thiazoler og oxazoler, laegemidler indeholdende disse forbindelser samt fremgangsmaade til deres fremstilling - Google Patents

Substituerede thiazoler og oxazoler, laegemidler indeholdende disse forbindelser samt fremgangsmaade til deres fremstilling

Info

Publication number: DK127487A
Authority: DK; Denmark
Prior art keywords: oxazoles; procedures; compounds; preparation; pharmaceuticals containing
Prior art date: 1986-03-13

Application number

DK127487A

Other languages

English (en)

Other versions

DK168991B1 (da

DK127487D0 (da

Inventor

Manfred Reifen

Rudolf Hurnaus

Robert Sauter

Wolfgang Grell

Eckhard Rupprecht

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-13

Filing date

1987-03-12

Publication date

1987-09-14

1986-03-13 Priority claimed from DE19863608290 external-priority patent/DE3608290A1/de

1987-03-12 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1987-03-12 Publication of DK127487D0 publication Critical patent/DK127487D0/da

1987-09-14 Publication of DK127487A publication Critical patent/DK127487A/da

1994-07-25 Application granted granted Critical

1994-07-25 Publication of DK168991B1 publication Critical patent/DK168991B1/da

Links

ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical class C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000003814 drug Chemical class 0.000 title 1
238000000034 method Methods 0.000 title 1
150000003557 thiazoles Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)

DK127487A 1986-03-13 1987-03-12 Substituerede thiazoler og oxazoler, lægemiddel indeholdende en sådan forbindelse, anvendelse af en sådan forbindelse til fremstilling af et lægemiddel, fremgangsmåde til fremstilling af lægemidlet og fremgangsmåde til fremstilling af forbindelserne, samt substituerede thiazoler og oxazoler med mellemproduktanvendelse DK168991B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE3608290		1986-03-13
DE19863608290 DE3608290A1 (de)	1986-03-13	1986-03-13	Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19863621775 DE3621775A1 (de)	1986-03-13	1986-06-28	Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3621775		1986-06-28

Publications (3)

Publication Number	Publication Date
DK127487D0 DK127487D0 (da)	1987-03-12
DK127487A true DK127487A (da)	1987-09-14
DK168991B1 DK168991B1 (da)	1994-07-25

Family

ID=25841907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK127487A DK168991B1 (da)	1986-03-13	1987-03-12	Substituerede thiazoler og oxazoler, lægemiddel indeholdende en sådan forbindelse, anvendelse af en sådan forbindelse til fremstilling af et lægemiddel, fremgangsmåde til fremstilling af lægemidlet og fremgangsmåde til fremstilling af forbindelserne, samt substituerede thiazoler og oxazoler med mellemproduktanvendelse

Country Status (19)

Country	Link
US (2)	US5457205A (da)
EP (1)	EP0239815B1 (da)
JP (1)	JPH0784446B2 (da)
KR (1)	KR870008876A (da)
CA (1)	CA1296002C (da)
DE (2)	DE3621775A1 (da)
DK (1)	DK168991B1 (da)
ES (1)	ES2040215T3 (da)
FI (1)	FI87777C (da)
GR (1)	GR3002839T3 (da)
HK (1)	HK106494A (da)
HU (1)	HU196974B (da)
IE (1)	IE59800B1 (da)
IL (1)	IL81874A (da)
MX (1)	MX9202818A (da)
NO (1)	NO172849C (da)
PH (1)	PH23996A (da)
PL (1)	PL154772B1 (da)
PT (1)	PT84462B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3805382A1 (de) *	1988-02-20	1989-08-31	Boehringer Ingelheim Vetmed	Verwendung von thiazolen zur leistungssteigerung bei tieren
JP3003148B2 (ja) *	1989-01-05	2000-01-24	藤沢薬品工業株式会社	チアゾール化合物、その製造法およびそれを含有する医薬組成物
AU660187B2 (en) *	1991-07-22	1995-06-15	Pfizer Inc.	Chiral intermediates for the preparation of antidiabetics thiazoles
WO1995002586A1 (en) *	1993-07-14	1995-01-26	Taisho Pharmaceutical Co., Ltd.	5-acetylthiazoline oxime derivative
DE69722258T2 (de)	1996-10-07	2004-03-18	Eli Lilly And Co., Indianapolis	Neue verbindungen nutlich als neuroschützende mittel
US6472387B1 (en)	1996-10-07	2002-10-29	Eli Lilly And Company	Methods of using compounds as neuro-protective agents
DE69738809D1 (de) *	1996-11-08	2008-08-14	Nippon Chemiphar Co	Mittel zur verringerung der eigeweidefette
CA2305538A1 (en)	1997-10-06	1999-04-15	David Lee Varie	Novel compounds useful as neuro-protective agents
US5972099A (en) *	1997-12-17	1999-10-26	Bayer Corporation	Process for preparing organic pigment compositions
US6121300A (en)	1998-11-10	2000-09-19	Wagle; Dilip R.	Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
WO2002044172A1 (en) *	2000-11-28	2002-06-06	Smithkline Beecham P.L.C.	Morpholine derivatives as antagonists of orexin receptors
RU2358722C2 (ru) *	2003-04-15	2009-06-20	Веллстат Терапьютикс Корпорейшн	Соединения для лечения метаболических расстройств
US7361686B2 (en)	2003-04-22	2008-04-22	Wellstat Therapeutics Corporation	Compounds for the treatment of metabolic disorders
GB0324654D0 (en) *	2003-10-22	2003-11-26	Glaxo Group Ltd	Medicinal compounds
TW200526588A (en) *	2003-11-17	2005-08-16	Smithkline Beecham Corp	Chemical compounds
WO2013062881A1 (en) *	2011-10-27	2013-05-02	Merck Sharp & Dohme Corp.	Process for making beta 3 agonists and intermediates
US10791890B2 (en)	2018-03-27	2020-10-06	Omachron Intellectual Property Inc.	Surface cleaning apparatus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3225042A (en) *	1962-07-31	1965-12-21	Lilly Co Eli	Hydroxymorpholines
US3514465A (en) *	1966-12-30	1970-05-26	Degussa	Certain thiazolyl- and pyridinylaminoketones
LU69079A1 (da) *	1973-12-27	1975-08-20
DD144050A5 (de) *	1978-06-05	1980-09-24	Ciba Geigy Ag	Verfahren zur herstellung von n-alkylierten aminoalkoholen
IE50355B1 (en) *	1979-10-20	1986-04-02	Wyeth John & Brother Ltd	Morpholine derivatives
GB8418657D0 (en) *	1984-07-21	1984-08-22	Beecham Group Plc	Compounds
US4826990A (en) *	1987-09-30	1989-05-02	American Home Products Corporation	2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents

1986
- 1986-06-28 DE DE19863621775 patent/DE3621775A1/de not_active Ceased
1987
- 1987-03-03 ES ES198787102995T patent/ES2040215T3/es not_active Expired - Lifetime
- 1987-03-03 DE DE8787102995T patent/DE3771541D1/de not_active Expired - Lifetime
- 1987-03-03 EP EP87102995A patent/EP0239815B1/de not_active Expired - Lifetime
- 1987-03-10 PL PL1987264545A patent/PL154772B1/pl unknown
- 1987-03-11 CA CA000531681A patent/CA1296002C/en not_active Expired - Lifetime
- 1987-03-11 FI FI871052A patent/FI87777C/fi not_active IP Right Cessation
- 1987-03-12 IL IL81874A patent/IL81874A/xx not_active IP Right Cessation
- 1987-03-12 DK DK127487A patent/DK168991B1/da active
- 1987-03-12 IE IE64487A patent/IE59800B1/en not_active IP Right Cessation
- 1987-03-12 NO NO871028A patent/NO172849C/no unknown
- 1987-03-12 HU HU871084A patent/HU196974B/hu not_active IP Right Cessation
- 1987-03-12 JP JP62055477A patent/JPH0784446B2/ja not_active Expired - Lifetime
- 1987-03-12 PT PT84462A patent/PT84462B/pt not_active IP Right Cessation
- 1987-03-13 KR KR870002258A patent/KR870008876A/ko not_active Ceased
- 1987-03-13 PH PH35027A patent/PH23996A/en unknown
1991
- 1991-10-03 GR GR91401473T patent/GR3002839T3/el unknown
1992
- 1992-06-12 MX MX9202818A patent/MX9202818A/es unknown
1993
- 1993-03-12 US US08/030,744 patent/US5457205A/en not_active Expired - Fee Related
1994
- 1994-10-06 HK HK106494A patent/HK106494A/xx not_active IP Right Cessation
1995
- 1995-05-24 US US08/449,174 patent/US5604225A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3771541D1 (de)	1991-08-29
EP0239815A1 (de)	1987-10-07
IL81874A (en)	1991-01-31
KR870008876A (ko)	1987-10-21
PT84462B (pt)	1989-10-04
NO871028D0 (no)	1987-03-12
IE870644L (en)	1987-09-13
PL154772B1 (en)	1991-09-30
DK168991B1 (da)	1994-07-25
NO172849B (no)	1993-06-07
IL81874A0 (en)	1987-10-20
FI87777C (fi)	1993-02-25
DK127487D0 (da)	1987-03-12
HU196974B (en)	1989-02-28
CA1296002C (en)	1992-02-18
US5457205A (en)	1995-10-10
NO172849C (no)	1993-09-15
MX9202818A (es)	1992-06-30
GR3002839T3 (en)	1993-01-25
ES2040215T3 (es)	1993-10-16
JPH0784446B2 (ja)	1995-09-13
FI871052A0 (fi)	1987-03-11
NO871028L (no)	1987-09-14
DE3621775A1 (de)	1988-01-07
HK106494A (en)	1994-10-14
IE59800B1 (en)	1994-04-06
EP0239815B1 (de)	1991-07-24
JPS62226971A (ja)	1987-10-05
PT84462A (de)	1987-04-01
US5604225A (en)	1997-02-18
FI871052A7 (fi)	1987-09-14
PL264545A1 (en)	1988-07-21
PH23996A (en)	1990-02-09
HUT44246A (en)	1988-02-29
FI87777B (fi)	1992-11-13

Publication	Publication Date	Title
DK231687A (da)	1987-11-08	Heterocykliske forbindelser, deres fremstilling og anvendelse, samt laegemidler indeholdende disse forbindelser
DK362787A (da)	1988-01-17	Benzensulfonamido-indanylforbindelser, laegemidler indeholdende disse forbindelser og fremgangsmaade til deres fremstilling
DK158587D0 (da)	1987-03-27	Thiazepinforbindelser, fremgangsmaader til fremstilling deraf samt farmaceutiske, praeparater, der indeholder disse forbindelser
DK209585D0 (da)	1985-05-10	Pyrrolobenzimidazoler, fremgangsmaade til deres fremstilling og laegemidler indeholdende disse forbindelser samt mellemprodukter
DK393482A (da)	1983-03-04	Urinstofderivater, fremgangsmaade til fremstilling heraf og medikamenter indeholdende disse forbindelser samt deres anvendelse
DK164868C (da)	1993-01-11	Imidazooe4,5-baaquinolin-2-on-derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK163991C (da)	1992-09-21	Dichloranilinderivater, fremgangsmaade til fremstilling af disse, samt farmaceutiske praeparater indeholdende derivaterne
DK219387A (da)	1987-10-30	Aminothiazol- og aminooxazolderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse
DK127487A (da)	1987-09-14	Substituerede thiazoler og oxazoler, laegemidler indeholdende disse forbindelser samt fremgangsmaade til deres fremstilling
DK451686D0 (da)	1986-09-22	Arylmethylazoler og deres salte, fremgangsmaade til fremstilling deraf, midler indeholdende disse forbindelser samt deres anvendelse
DK165367C (da)	1993-04-05	Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser
DK206785A (da)	1985-11-18	Benzazepinderivater, laegemidler indeholdende disse samt fremgangsmaade til fremstilling deraf
DK486789A (da)	1990-04-05	Benzoxazolinonderivater, fremgangsmaader til fremstilling deraf samt farmaceutiske midler indeholdende disse
DK66086A (da)	1986-08-12	Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK457787D0 (da)	1987-09-02	Sulfonamidoethylforbindelser, laegemidler indeholdende disse forbindelser og fremgangsmaade til deres fremstilling
DK572785A (da)	1986-06-13	Imidazolderivater, laegemidler indeholdende disse forbindelser og fremgangsmaader til deres fremstilling
DK307085D0 (da)	1985-07-04	4-phenyl-2-trifluormethyl-1,3-dioxan-5-ylheptensyrederivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse
DK162984C (da)	1992-06-01	1-(2-ar-2-halogen-2-ethenyl)-1h-azoler, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse
DK191086D0 (da)	1986-04-24	Benzisoselenazolonylderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK553689D0 (da)	1989-11-07	Phenyloxypropanolaminderivater, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse
DK90189D0 (da)	1989-02-24	Trisubstituerede aminer, fremgangsmaade til deres fremstilling samt laegemidler indeholdende disse forbindelser
NO871375D0 (no)	1987-04-02	Bis-tertiaerbutylamino-substituerte 1,3,5-triazinderivater, fremgangsmaate til deres fremstilling, legemidler inneholdende disse forbindelser og deres anvendelse.
DK165978C (da)	1993-07-26	1-aminoethyl-1h-imidazolderivater, fremgangsmaader til fremstilling deraf samt antimykotiske midler indeholdende disse
DK240984D0 (da)	1984-05-16	5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarboxylsyrer,fremgangsmaader til deres fremstilling samt farmaceutiske praeparater indeholdende disse
DK501385A (da)	1986-10-13	1,3,4-thiadiazolderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser