DK408186D0 - Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne - Google Patents

Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne

Info

Publication number: DK408186D0
Authority: DK; Denmark
Prior art keywords: podophyllotoxin; procedures; derivatives; compounds; preparation
Prior art date: 1984-12-28

Application number

DK408186A

Other languages

English (en)

Other versions

DK169506B1 (da

DK408186A (da

Inventor

Boerje Rosen

Kurt Leander

Original Assignee

Conpharm Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-28

Filing date

1986-08-27

Publication date

1986-08-27

1986-08-27 Application filed by Conpharm Ab filed Critical Conpharm Ab

1986-08-27 Publication of DK408186D0 publication Critical patent/DK408186D0/da

1986-08-27 Publication of DK408186A publication Critical patent/DK408186A/da

1994-11-14 Application granted granted Critical

1994-11-14 Publication of DK169506B1 publication Critical patent/DK169506B1/da

Links

150000001875 compounds Chemical class 0.000 title 1
YJGVMLPVUAXIQN-UHFFFAOYSA-N epipodophyllotoxin Natural products COC1=C(OC)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YJGVMLPVUAXIQN-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
YJGVMLPVUAXIQN-XVVDYKMHSA-N podophyllotoxin Chemical compound COC1=C(OC)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YJGVMLPVUAXIQN-XVVDYKMHSA-N 0.000 title 1
229960001237 podophyllotoxin Drugs 0.000 title 1
YVCVYCSAAZQOJI-UHFFFAOYSA-N podophyllotoxin Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YVCVYCSAAZQOJI-UHFFFAOYSA-N 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Dermatology (AREA)
Tropical Medicine & Parasitology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK408186A 1984-12-28 1986-08-27 Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme DK169506B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8406660		1984-12-28
SE8406660		1984-12-28
PCT/SE1985/000541 WO1986004062A1 (en)	1984-12-28	1985-12-20	Pharmaceutically active compound and a method for its preparation
SE8500541		1985-12-20

Publications (3)

Publication Number	Publication Date
DK408186D0 true DK408186D0 (da)	1986-08-27
DK408186A DK408186A (da)	1986-08-27
DK169506B1 DK169506B1 (da)	1994-11-14

Family

ID=20358339

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK408186A DK169506B1 (da)	1984-12-28	1986-08-27	Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme

Country Status (23)

Country	Link
US (1)	US4788216A (da)
EP (1)	EP0207124B1 (da)
JP (2)	JPH0720966B2 (da)
CN (1)	CN1006795B (da)
AP (1)	AP32A (da)
AT (1)	ATE68186T1 (da)
AU (1)	AU585936B2 (da)
CA (1)	CA1255230A (da)
DE (1)	DE3584370D1 (da)
DK (1)	DK169506B1 (da)
DZ (1)	DZ876A1 (da)
EG (1)	EG17788A (da)
ES (1)	ES8701761A1 (da)
FI (1)	FI89330C (da)
GR (1)	GR853145B (da)
HU (1)	HU201672B (da)
IL (1)	IL77456A (da)
MA (1)	MA20602A1 (da)
NO (1)	NO863329D0 (da)
PT (1)	PT81760B (da)
TN (1)	TNSN86004A1 (da)
WO (1)	WO1986004062A1 (da)
ZA (1)	ZA859881B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4644072A (en) *	1985-04-12	1987-02-17	Bristol-Myers Company	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
AU632796B2 (en) *	1989-02-23	1993-01-14	University Of North Carolina At Chapel Hill, The	Etoposide analogues
SE464167B (sv)	1989-07-31	1991-03-18	Analytecon Sa	Topisk farmaceutisk beredning av podophyllotoxin
US5332811A (en) *	1989-09-12	1994-07-26	The University Of North Carolina At Chapel Hill	Etopside analogs
US5338867A (en) *	1992-04-24	1994-08-16	Genelabs Technologies, Inc.	Preparation of 4β- amino podophyllotoxin compounds
SE9301831D0 (sv) *	1993-05-28	1993-05-28	Analytecon S A	Pharmaceutical compositions
GB9422947D0 (en) *	1994-11-14	1995-01-04	Univ Salamanca	Immunosuppressive cyclolignan derivatives
US6051721A (en) *	1997-10-02	2000-04-18	The Board Of Regents Of The University Of Nebraska	Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
FI105152B (fi) *	1998-07-17	2000-06-30	Eero Saarela	Paikallinen kivunlievitysmenetelmä
US6143304A (en) *	1999-08-17	2000-11-07	The University Of Mississippi	Enhanced yield of podophyllotoxin from natural products through in situ conversion methods
SE0102168D0 (sv) *	2001-06-19	2001-06-19	Karolinska Innovations Ab	New use and new compounds
KR20040030686A (ko) *	2001-06-19	2004-04-09	악셀라르 아베	시클로리그난의 신규의 용도 및 신규의 시클로리그난
SE0203746D0 (sv) *	2002-12-18	2002-12-18	Karolinska Innovations Ab	New compounds
CN102083431A (zh) *	2008-06-23	2011-06-01	阿克塞拉公司	环木脂体在治疗免疫系统亢奋中的用途
EP2817007A1 (en) *	2012-02-24	2014-12-31	Nestec S.A.	Peltatin for the treatment of chronic inflammatory disorders
WO2015028456A1 (en) *	2013-08-28	2015-03-05	Nestec S.A.	PPAR modulators
LT3615544T (lt)	2017-04-27	2023-05-10	Pharma Mar S.A.	Priešnavikiniai junginiai
US20220226480A1 (en) *	2019-03-22	2022-07-21	Integrated Nanotherapeutics Inc.	Lipid conjugate prepared from scaffold moiety

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA635769A (en) *		1962-01-30	Rutschmann Jurg	Amides of podophyllic acid and picropodophyllic acid
SE335139B (da) *	1964-08-12	1971-05-17	Sandoz Ag
US4122092A (en) *	1977-08-25	1978-10-24	University Of Rochester	Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
US4567253A (en) *	1984-02-03	1986-01-28	Tony Durst	2-Substituted derivatives of podophyllotoxin and etoposide
GB8424269D0 (en) *	1984-09-26	1984-10-31	Pharma Medica As	Isolation and purification of podophyllotoxin

1985
- 1985-12-20 US US06/908,801 patent/US4788216A/en not_active Expired - Lifetime
- 1985-12-20 JP JP61500490A patent/JPH0720966B2/ja not_active Expired - Lifetime
- 1985-12-20 AT AT86900345T patent/ATE68186T1/de not_active IP Right Cessation
- 1985-12-20 HU HU86777D patent/HU201672B/hu not_active IP Right Cessation
- 1985-12-20 AU AU53003/86A patent/AU585936B2/en not_active Ceased
- 1985-12-20 EP EP86900345A patent/EP0207124B1/en not_active Expired - Lifetime
- 1985-12-20 DE DE8686900345T patent/DE3584370D1/de not_active Expired - Fee Related
- 1985-12-20 WO PCT/SE1985/000541 patent/WO1986004062A1/en not_active Ceased
- 1985-12-23 AP APAP/P/1985/000017A patent/AP32A/en active
- 1985-12-24 CA CA000498645A patent/CA1255230A/en not_active Expired
- 1985-12-25 EG EG828/85A patent/EG17788A/xx active
- 1985-12-26 IL IL77456A patent/IL77456A/xx unknown
- 1985-12-26 MA MA20828A patent/MA20602A1/fr unknown
- 1985-12-26 PT PT81760A patent/PT81760B/pt not_active IP Right Cessation
- 1985-12-27 ES ES550504A patent/ES8701761A1/es not_active Expired
- 1985-12-27 CN CN85109666A patent/CN1006795B/zh not_active Expired
- 1985-12-27 GR GR853145A patent/GR853145B/el not_active IP Right Cessation
- 1985-12-28 DZ DZ850275A patent/DZ876A1/fr active
- 1985-12-30 ZA ZA859881A patent/ZA859881B/xx unknown
1986
- 1986-01-09 TN TNTNSN86004A patent/TNSN86004A1/fr unknown
- 1986-08-19 NO NO1986863329A patent/NO863329D0/no unknown
- 1986-08-27 DK DK408186A patent/DK169506B1/da not_active IP Right Cessation
- 1986-08-27 FI FI863482A patent/FI89330C/fi not_active IP Right Cessation
1994
- 1994-10-14 JP JP6274258A patent/JP2572558B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUT47582A (en)	1989-03-28
DZ876A1 (fr)	2004-09-13
FI863482L (fi)	1986-08-27
US4788216A (en)	1988-11-29
CN1006795B (zh)	1990-02-14
JPH07173063A (ja)	1995-07-11
CA1255230A (en)	1989-06-06
GR853145B (da)	1986-04-29
JP2572558B2 (ja)	1997-01-16
NO863329L (no)	1986-08-19
ZA859881B (en)	1986-09-24
AP32A (en)	1988-12-07
JPH0720966B2 (ja)	1995-03-08
MA20602A1 (fr)	1986-07-01
ES8701761A1 (es)	1986-12-01
FI863482A0 (fi)	1986-08-27
JPS62501360A (ja)	1987-06-04
PT81760A (en)	1986-01-02
ES550504A0 (es)	1986-12-01
DE3584370D1 (de)	1991-11-14
CN85109666A (zh)	1986-10-29
NO863329D0 (no)	1986-08-19
IL77456A (en)	1989-07-31
ATE68186T1 (de)	1991-10-15
EP0207124B1 (en)	1991-10-09
DK169506B1 (da)	1994-11-14
AU5300386A (en)	1986-07-29
DK408186A (da)	1986-08-27
IL77456A0 (en)	1986-08-31
AP8500017A0 (en)	1985-11-01
AU585936B2 (en)	1989-06-29
PT81760B (pt)	1987-11-11
FI89330B (fi)	1993-06-15
HU201672B (en)	1990-12-28
WO1986004062A1 (en)	1986-07-17
EP0207124A1 (en)	1987-01-07
TNSN86004A1 (fr)	1990-01-01
EG17788A (en)	1990-12-30
FI89330C (fi)	1993-09-27

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Legal Events

Date	Code	Title	Description
1994-11-14	B1	Patent granted (law 1993)
2002-08-05	PBP	Patent lapsed