DK1276483T3 - Sammensætninger og fremgangsmåder til at behandle amyloidose ved anvendelse af sulfonatderivater - Google Patents
Sammensætninger og fremgangsmåder til at behandle amyloidose ved anvendelse af sulfonatderivaterInfo
- Publication number
- DK1276483T3 DK1276483T3 DK00922395T DK00922395T DK1276483T3 DK 1276483 T3 DK1276483 T3 DK 1276483T3 DK 00922395 T DK00922395 T DK 00922395T DK 00922395 T DK00922395 T DK 00922395T DK 1276483 T3 DK1276483 T3 DK 1276483T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen atom
- independently
- methods
- therapeutic compound
- Prior art date
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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Applications Claiming Priority (4)
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| US13554599P | 1999-05-24 | 1999-05-24 | |
| US14312399P | 1999-07-09 | 1999-07-09 | |
| PCT/CA2000/000494 WO2000064420A2 (en) | 1999-04-28 | 2000-04-28 | Compositions and methods for treating amyloidosis using sulphonate derivatives |
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| DK1276483T3 true DK1276483T3 (da) | 2009-12-14 |
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| DK00922395T DK1276483T3 (da) | 1999-04-28 | 2000-04-28 | Sammensætninger og fremgangsmåder til at behandle amyloidose ved anvendelse af sulfonatderivater |
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| JP (1) | JP4726304B2 (da) |
| KR (2) | KR20070094996A (da) |
| CN (1) | CN100482233C (da) |
| AT (1) | ATE441421T1 (da) |
| AU (1) | AU4282400A (da) |
| BR (1) | BR0010099A (da) |
| CA (1) | CA2369997C (da) |
| DE (1) | DE60042896D1 (da) |
| DK (1) | DK1276483T3 (da) |
| ES (1) | ES2331905T3 (da) |
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| MX (1) | MXPA01010835A (da) |
| NZ (1) | NZ543319A (da) |
| WO (1) | WO2000064420A2 (da) |
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| US20040208875A1 (en) * | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| AU5994900A (en) * | 1999-07-09 | 2001-01-30 | Isis Innovation Limited | Compounds for inhibiting diseases and preparing cells for transplantation |
| US7311893B2 (en) | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
| US6716589B2 (en) * | 2000-11-20 | 2004-04-06 | Alphabeta Ab | Discordant helix stabilization for prevention of amyloid formation |
| US20070129438A1 (en) * | 2002-07-11 | 2007-06-07 | Yuuichi Murayama | Method for suppressing proliferation of abnormal prion protein |
| WO2004058239A1 (en) * | 2002-12-24 | 2004-07-15 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| US7253306B2 (en) | 2003-06-23 | 2007-08-07 | Neurochem (International) Limited | Pharmaceutical drug candidates and methods for preparation thereof |
| MXPA05013607A (es) * | 2003-06-23 | 2006-04-06 | Neurochem Int Ltd | Candidatos de farmaco farmaceuticos mejorados y metodos para preparar los mismos. |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| US20050142191A1 (en) * | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| EP1658264A2 (en) * | 2003-06-23 | 2006-05-24 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| BRPI0517790A (pt) * | 2004-11-12 | 2008-10-21 | Neurochem Int Ltd | métodos e composições fluoradas para tratar doenças relacionadas à amilóide |
| CA2586334A1 (en) * | 2004-11-16 | 2006-06-08 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
| WO2006085149A2 (en) * | 2004-12-22 | 2006-08-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
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2000
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- 2000-04-28 MX MXPA01010835A patent/MXPA01010835A/es active IP Right Grant
- 2000-04-28 CN CNB008094152A patent/CN100482233C/zh not_active Expired - Fee Related
- 2000-04-28 AT AT00922395T patent/ATE441421T1/de not_active IP Right Cessation
- 2000-04-28 EP EP00922395A patent/EP1276483B1/en not_active Expired - Lifetime
- 2000-04-28 IL IL14614300A patent/IL146143A0/xx unknown
- 2000-04-28 BR BR0010099-4A patent/BR0010099A/pt not_active IP Right Cessation
- 2000-04-28 KR KR1020077021102A patent/KR20070094996A/ko not_active Abandoned
- 2000-04-28 KR KR1020017013824A patent/KR100822525B1/ko not_active Expired - Fee Related
- 2000-04-28 DE DE60042896T patent/DE60042896D1/de not_active Expired - Lifetime
- 2000-04-28 WO PCT/CA2000/000494 patent/WO2000064420A2/en not_active Ceased
- 2000-04-28 AU AU42824/00A patent/AU4282400A/en not_active Abandoned
- 2000-04-28 ES ES00922395T patent/ES2331905T3/es not_active Expired - Lifetime
- 2000-04-28 DK DK00922395T patent/DK1276483T3/da active
- 2000-04-28 JP JP2000613411A patent/JP4726304B2/ja not_active Expired - Fee Related
- 2000-04-28 CA CA002369997A patent/CA2369997C/en not_active Expired - Fee Related
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2003
- 2003-08-11 US US10/639,609 patent/US20040198832A1/en not_active Abandoned
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2008
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-
2011
- 2011-04-14 US US13/066,451 patent/US20110281951A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1276483A2 (en) | 2003-01-22 |
| ATE441421T1 (de) | 2009-09-15 |
| KR20020010138A (ko) | 2002-02-02 |
| JP2003517458A (ja) | 2003-05-27 |
| NZ543319A (en) | 2007-06-29 |
| IL146143A0 (en) | 2002-07-25 |
| CN1523992A (zh) | 2004-08-25 |
| KR100822525B1 (ko) | 2008-04-16 |
| CA2369997C (en) | 2009-11-17 |
| US20040198832A1 (en) | 2004-10-07 |
| ES2331905T3 (es) | 2010-01-20 |
| CA2369997A1 (en) | 2000-11-02 |
| WO2000064420A2 (en) | 2000-11-02 |
| EP1276483B1 (en) | 2009-09-02 |
| US20110281951A1 (en) | 2011-11-17 |
| US20090099100A1 (en) | 2009-04-16 |
| KR20070094996A (ko) | 2007-09-27 |
| DE60042896D1 (de) | 2009-10-15 |
| AU4282400A (en) | 2000-11-10 |
| MXPA01010835A (es) | 2003-07-14 |
| BR0010099A (pt) | 2002-06-04 |
| HK1054862A1 (en) | 2003-12-19 |
| CN100482233C (zh) | 2009-04-29 |
| WO2000064420A3 (en) | 2002-11-07 |
| JP4726304B2 (ja) | 2011-07-20 |
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