DK127786A - Fremgangsmaade til fremstilling af tgf-beta, dna og mrna, som koder for tgf-beta, samt replicerbare vektorer omfattende dna'en og vaertsceller indeholdende vektorerne - Google Patents

Fremgangsmaade til fremstilling af tgf-beta, dna og mrna, som koder for tgf-beta, samt replicerbare vektorer omfattende dna'en og vaertsceller indeholdende vektorerne Download PDF

Info

Publication number: DK127786A
Authority: DK; Denmark
Prior art keywords: beta; tgf; dna; vectors; manufacturing
Prior art date: 1985-03-22

Application number

DK127786A

Other languages

English (en)

Other versions

DK175412B1 (da

DK127786D0 (da

Inventor

Rik Michel Andre Derynck

David Vannorman Goeddel

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-22

Filing date

1986-03-20

Publication date

1986-09-23

1986-03-20 Application filed by Genentech Inc filed Critical Genentech Inc

1986-03-20 Publication of DK127786D0 publication Critical patent/DK127786D0/da

1986-09-23 Publication of DK127786A publication Critical patent/DK127786A/da

2004-09-27 Application granted granted Critical

2004-09-27 Publication of DK175412B1 publication Critical patent/DK175412B1/da

Links

ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 4
239000013598 vector Substances 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 abstract 2
102000039446 nucleic acids Human genes 0.000 abstract 2
108020004707 nucleic acids Proteins 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
210000003527 eukaryotic cell Anatomy 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK198601277A 1985-03-22 1986-03-20 Fremgangsmåde til fremstilling af TGF-beta, DNA og mRNA, som koder for TGF-beta, samt replicerbare vektorer omfattende DNA'en og værtsceller indeholdende vektorerne DK175412B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71514285A	1985-03-22	1985-03-22
US71514285		1985-03-22

Publications (3)

Publication Number	Publication Date
DK127786D0 DK127786D0 (da)	1986-03-20
DK127786A true DK127786A (da)	1986-09-23
DK175412B1 DK175412B1 (da)	2004-09-27

Family

ID=24872822

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198601277A DK175412B1 (da)	1985-03-22	1986-03-20	Fremgangsmåde til fremstilling af TGF-beta, DNA og mRNA, som koder for TGF-beta, samt replicerbare vektorer omfattende DNA'en og værtsceller indeholdende vektorerne

Country Status (7)

Country	Link
EP (1)	EP0200341B1 (da)
JP (2)	JPH0659230B2 (da)
AT (1)	ATE99737T1 (da)
DE (1)	DE3689495T2 (da)
DK (1)	DK175412B1 (da)
IE (1)	IE61119B1 (da)
IL (1)	IL78197A (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ222168A (en) *	1986-10-20	1991-05-28	Oncogene Science Inc	Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
US4931548A (en) *	1987-01-30	1990-06-05	Techne Corporation	Heterodimer form of transforming growth factor-beta
WO1988005787A1 (en) *	1987-01-30	1988-08-11	Techne Corporation	Transforming growth factor-beta
JPS6463395A (en) *	1987-05-04	1989-03-09	Oncogen	Oncostatin m and novel composition having antitumor activity
AU1539188A (en) *	1987-05-04	1988-11-10	Bristol-Myers Squibb Company	TGF-B2 and novel compositions having anti-neoplastic activity
EP0293785A3 (en) *	1987-05-29	1990-05-02	Oncogen Limited Partnership	Cloning and expression of simian transforming growth factor-ss1
IL87877A0 (en) *	1987-10-06	1989-03-31	Oncogen	Cloning and expression of transforming growth factor beta2
US5221620A (en) *	1987-10-06	1993-06-22	Oncogen	Cloning and expression of transforming growth factor β2
EP0418234B1 (en) *	1988-06-08	1994-03-23	Genentech, Inc.	NUCLEIC ACID ENCODING TGF-$g(b)3 AND ITS USE
IL94878A (en) *	1989-06-28	2003-01-12	Schering Corp	Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
US5158934A (en) *	1989-09-01	1992-10-27	Genentech, Inc.	Method of inducing bone growth using TGF-β
US5422340A (en) *	1989-09-01	1995-06-06	Ammann; Arthur J.	TGF-βformulation for inducing bone growth
CA2070393A1 (en) *	1989-10-18	1991-04-19	Charles M. Cohen	Biosynthetic constructs of tgf-beta
GB8927546D0 (en) *	1989-12-06	1990-02-07	Ciba Geigy	Process for the production of biologically active tgf-beta
GB9106678D0 (en) *	1991-03-28	1991-05-15	Ferguson Mark W J	Wound healing
TW517059B (en)	1994-07-25	2003-01-11	Ciba Geigy Ag	New process for the production of biologically active protein
DE69726870T2 (de) *	1996-07-29	2004-10-28	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh	EGF-ähnlicher Faktor von Chromaffingranula und von Gliazellen stammender neurotropher Faktor mit überlebensfördernder Aktivität auf dopaminerge Neuronen
GB9822682D0 (en) *	1998-10-16	1998-12-09	Gemini Research Limited	Diagnostic method and apparatus based on polymorphism in a TGF-B-Gene
JP2002539172A (ja)	1999-03-17	2002-11-19	ノバルティスアクチエンゲゼルシャフト	Ｔｇｆ−ベータを含む医薬組成物
US7211271B2 (en)	2001-03-12	2007-05-01	The Regents Of The University Of California	Method to improve hydroxyapatite implantation and stimulate bone regeneration
EP1740615B1 (en)	2004-03-31	2014-11-05	Genentech, Inc.	Humanized anti-tgf-beta antibodies
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604938D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Proteins, nucleic acids and medicaments
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
KR20090105913A (ko)	2006-11-02	2009-10-07	다니엘 제이 카폰	이동 부분을 갖는 하이브리드 면역글로불린
JP7125933B2 (ja) *	2017-05-02	2022-08-25	株式会社カネカ	免疫グロブリン結合活性を有するポリペプチドの回収精製法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3587022T2 (de) *	1984-02-17	1993-06-17	Genentech Inc	Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.

1986
- 1986-03-19 IL IL78197A patent/IL78197A/xx unknown
- 1986-03-20 JP JP61064661A patent/JPH0659230B2/ja not_active Expired - Lifetime
- 1986-03-20 DK DK198601277A patent/DK175412B1/da not_active IP Right Cessation
- 1986-03-21 IE IE74386A patent/IE61119B1/en not_active IP Right Cessation
- 1986-03-21 AT AT86302112T patent/ATE99737T1/de not_active IP Right Cessation
- 1986-03-21 DE DE3689495T patent/DE3689495T2/de not_active Expired - Lifetime
- 1986-03-21 EP EP86302112A patent/EP0200341B1/en not_active Expired - Lifetime
1993
- 1993-09-13 JP JP5227016A patent/JPH0763378B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE860743L (en)	1986-09-22
DE3689495D1 (de)	1994-02-17
DK175412B1 (da)	2004-09-27
JPH0659230B2 (ja)	1994-08-10
JPS61219395A (ja)	1986-09-29
JPH0763378B2 (ja)	1995-07-12
IL78197A (en)	1991-07-18
IE61119B1 (en)	1994-10-05
EP0200341B1 (en)	1994-01-05
EP0200341A1 (en)	1986-11-05
DK127786D0 (da)	1986-03-20
ATE99737T1 (de)	1994-01-15
DE3689495T2 (de)	1994-06-01
IL78197A0 (en)	1986-07-31
JPH06169777A (ja)	1994-06-21

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Legal Events

Date	Code	Title	Description
2006-04-03	PUP	Patent expired