ATE99737T1 - Tgf-beta codierende nucleinsaeure und deren verwendungen. - Google Patents

Tgf-beta codierende nucleinsaeure und deren verwendungen.

Info

Publication number: ATE99737T1
Authority: AT; Austria
Prior art keywords: nucleic acid; tgf; beta; encoding nucleic; beta encoding
Prior art date: 1985-03-22

Application number

AT86302112T

Other languages

English (en)

Inventor

Rik Michel Andre Derynck

David Vannorman Goeddel

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-22

Filing date

1986-03-21

Publication date

1994-01-15

1986-03-21 Application filed by Genentech Inc filed Critical Genentech Inc

1994-01-15 Application granted granted Critical

1994-01-15 Publication of ATE99737T1 publication Critical patent/ATE99737T1/de

Links

150000007523 nucleic acids Chemical class 0.000 title abstract 3
102000039446 nucleic acids Human genes 0.000 title abstract 3
108020004707 nucleic acids Proteins 0.000 title abstract 3
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 3
241000894006 Bacteria Species 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
210000003527 eukaryotic cell Anatomy 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT86302112T 1985-03-22 1986-03-21 Tgf-beta codierende nucleinsaeure und deren verwendungen. ATE99737T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71514285A	1985-03-22	1985-03-22
EP86302112A EP0200341B1 (de)	1985-03-22	1986-03-21	TGF-beta codierende Nucleinsäure und deren Verwendungen

Publications (1)

Publication Number	Publication Date
ATE99737T1 true ATE99737T1 (de)	1994-01-15

Family

ID=24872822

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86302112T ATE99737T1 (de)	1985-03-22	1986-03-21	Tgf-beta codierende nucleinsaeure und deren verwendungen.

Country Status (7)

Country	Link
EP (1)	EP0200341B1 (de)
JP (2)	JPH0659230B2 (de)
AT (1)	ATE99737T1 (de)
DE (1)	DE3689495T2 (de)
DK (1)	DK175412B1 (de)
IE (1)	IE61119B1 (de)
IL (1)	IL78197A (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ222168A (en) *	1986-10-20	1991-05-28	Oncogene Science Inc	Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
US4931548A (en) *	1987-01-30	1990-06-05	Techne Corporation	Heterodimer form of transforming growth factor-beta
WO1988005787A1 (en) *	1987-01-30	1988-08-11	Techne Corporation	Transforming growth factor-beta
AU1539188A (en) *	1987-05-04	1988-11-10	Bristol-Myers Squibb Company	TGF-B2 and novel compositions having anti-neoplastic activity
JPS6463395A (en) *	1987-05-04	1989-03-09	Oncogen	Oncostatin m and novel composition having antitumor activity
EP0293785A3 (de)	1987-05-29	1990-05-02	Oncogen Limited Partnership	Klonierung und Expression von transformierendem Affenwachstumsfaktor-SS 1
US5221620A (en) *	1987-10-06	1993-06-22	Oncogen	Cloning and expression of transforming growth factor β2
IL87877A0 (en) *	1987-10-06	1989-03-31	Oncogen	Cloning and expression of transforming growth factor beta2
EP0418234B1 (de) *	1988-06-08	1994-03-23	Genentech, Inc.	Nukleinsäure, die tgf-b3 kodiert, und ihre verwendung
IL94878A (en) *	1989-06-28	2003-01-12	Schering Corp	Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
US5158934A (en) *	1989-09-01	1992-10-27	Genentech, Inc.	Method of inducing bone growth using TGF-β
US5422340A (en) *	1989-09-01	1995-06-06	Ammann; Arthur J.	TGF-βformulation for inducing bone growth
CA2070393A1 (en) *	1989-10-18	1991-04-19	Charles M. Cohen	Biosynthetic constructs of tgf-beta
GB8927546D0 (en) *	1989-12-06	1990-02-07	Ciba Geigy	Process for the production of biologically active tgf-beta
GB9106678D0 (en) *	1991-03-28	1991-05-15	Ferguson Mark W J	Wound healing
TW517059B (en)	1994-07-25	2003-01-11	Ciba Geigy Ag	New process for the production of biologically active protein
WO1998004688A1 (en) *	1996-07-29	1998-02-05	Biopharm Gmbh	Egf-like factor from chromaffin granules and glia cell-derived neurotrophic factor with survival-promoting activity on daergic neurons
GB9822682D0 (en) *	1998-10-16	1998-12-09	Gemini Research Limited	Diagnostic method and apparatus based on polymorphism in a TGF-B-Gene
JP2002539172A (ja)	1999-03-17	2002-11-19	ノバルティスアクチエンゲゼルシャフト	Ｔｇｆ−ベータを含む医薬組成物
US7211271B2 (en)	2001-03-12	2007-05-01	The Regents Of The University Of California	Method to improve hydroxyapatite implantation and stimulate bone regeneration
RU2386638C2 (ru)	2004-03-31	2010-04-20	Дженентек, Инк.	Гуманизированные анти-тфр-бета-антитела
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
GB0604938D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Proteins, nucleic acids and medicaments
NZ576445A (en)	2006-11-02	2012-03-30	Daniel J Capon	Hybrid immunoglobulins with moving parts
JP7125933B2 (ja) *	2017-05-02	2022-08-25	株式会社カネカ	免疫グロブリン結合活性を有するポリペプチドの回収精製法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3587022T2 (de) *	1984-02-17	1993-06-17	Genentech Inc	Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.

1986
- 1986-03-19 IL IL78197A patent/IL78197A/xx unknown
- 1986-03-20 DK DK198601277A patent/DK175412B1/da not_active IP Right Cessation
- 1986-03-20 JP JP61064661A patent/JPH0659230B2/ja not_active Expired - Lifetime
- 1986-03-21 EP EP86302112A patent/EP0200341B1/de not_active Expired - Lifetime
- 1986-03-21 AT AT86302112T patent/ATE99737T1/de not_active IP Right Cessation
- 1986-03-21 IE IE74386A patent/IE61119B1/en not_active IP Right Cessation
- 1986-03-21 DE DE3689495T patent/DE3689495T2/de not_active Expired - Lifetime
1993
- 1993-09-13 JP JP5227016A patent/JPH0763378B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPS61219395A (ja)	1986-09-29
IE860743L (en)	1986-09-22
IL78197A (en)	1991-07-18
JPH0763378B2 (ja)	1995-07-12
DK127786D0 (da)	1986-03-20
IE61119B1 (en)	1994-10-05
DE3689495T2 (de)	1994-06-01
JPH0659230B2 (ja)	1994-08-10
DK127786A (da)	1986-09-23
JPH06169777A (ja)	1994-06-21
IL78197A0 (en)	1986-07-31
DK175412B1 (da)	2004-09-27
DE3689495D1 (de)	1994-02-17
EP0200341A1 (de)	1986-11-05
EP0200341B1 (de)	1994-01-05

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Legal Events

Date	Code	Title	Description
1994-10-15	UEP	Publication of translation of european patent specification
2006-06-15	EELA	Cancelled due to lapse of time