DK1293507T3 - Fremgangsmåde til fremstilling af krystaller - Google Patents

Fremgangsmåde til fremstilling af krystaller

Info

Publication number
DK1293507T3
DK1293507T3 DK01930131T DK01930131T DK1293507T3 DK 1293507 T3 DK1293507 T3 DK 1293507T3 DK 01930131 T DK01930131 T DK 01930131T DK 01930131 T DK01930131 T DK 01930131T DK 1293507 T3 DK1293507 T3 DK 1293507T3
Authority
DK
Denmark
Prior art keywords
producing crystals
crystals
producing
Prior art date
Application number
DK01930131T
Other languages
English (en)
Inventor
Hideo Hashimoto
Hideaki Maruyama
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of DK1293507T3 publication Critical patent/DK1293507T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C30CRYSTAL GROWTH
    • C30BSINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01930131T 2000-05-15 2001-05-15 Fremgangsmåde til fremstilling af krystaller DK1293507T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000141670 2000-05-15
PCT/JP2001/004014 WO2001087874A1 (en) 2000-05-15 2001-05-15 Process for producing crystal

Publications (1)

Publication Number Publication Date
DK1293507T3 true DK1293507T3 (da) 2007-12-27

Family

ID=18648753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01930131T DK1293507T3 (da) 2000-05-15 2001-05-15 Fremgangsmåde til fremstilling af krystaller

Country Status (12)

Country Link
US (4) US7169799B2 (da)
EP (3) EP2281821B1 (da)
KR (2) KR101035534B1 (da)
CN (2) CN1280287C (da)
AU (1) AU2001256732A1 (da)
CA (3) CA2701704C (da)
CY (1) CY1107198T1 (da)
DE (1) DE60131649T2 (da)
DK (1) DK1293507T3 (da)
ES (3) ES2521690T3 (da)
PT (1) PT1293507E (da)
WO (1) WO2001087874A1 (da)

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DE60131649T2 (de) * 2000-05-15 2008-10-30 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung eines kristalls
JP5412023B2 (ja) * 2000-08-04 2014-02-12 武田薬品工業株式会社 ベンズイミダゾール化合物の塩およびその用途
KR20100002278A (ko) 2000-12-01 2010-01-06 다케다 야쿠힌 고교 가부시키가이샤 (r)- 또는 (s)-란소프라졸의 결정
WO2004035052A1 (ja) * 2002-10-16 2004-04-29 Takeda Pharmaceutical Company Limited 安定な固形製剤
CA2510849A1 (en) * 2002-12-19 2004-07-08 Teva Pharmaceutical Industries Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
ATE508747T1 (de) * 2003-03-10 2011-05-15 Eisai R&D Man Co Ltd C-kit kinase-hemmer
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8461187B2 (en) * 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
CA2602097A1 (en) * 2005-03-22 2006-09-28 Daiichi Sankyo Company, Limited Process for producing carbapenem derivatives having 1-alkylpyrrolidine structure
TW200639176A (en) * 2005-05-13 2006-11-16 Sankyo Co Crystal of 1-methyl carbapenem compound
US20090030044A1 (en) * 2005-06-07 2009-01-29 Takeda Pharmaceutical Company Limited Crystal of Salt of Benzimidazole Compound
RU2496480C2 (ru) 2005-12-28 2013-10-27 Такеда Фармасьютикал Компани Лимитед Твердый препарат с контролируемым высвобождением
EP2098250B1 (en) 2006-12-28 2016-09-28 Takeda Pharmaceutical Company Limited Orally disintegrating solid preparation
WO2009049160A1 (en) * 2007-10-12 2009-04-16 Takeda Pharmaceuticals North America Methods of treating gastrointestinal disorders independent of the intake of food
US8214093B2 (en) * 2007-11-04 2012-07-03 GM Global Technology Operations LLC Method and apparatus to prioritize transmission output torque and input acceleration for a hybrid powertrain system
JP2011507977A (ja) * 2007-12-31 2011-03-10 武田薬品工業株式会社 (r)−2−[[[3−メチル−4−(2,2,2−トリフルオロエトキシ)−2−ピリジニル]メチル]スルフィニル]−1h−ベンズイミダゾールの溶媒和物結晶形
EA017064B1 (ru) * 2008-03-10 2012-09-28 Такеда Фармасьютикал Компани Лимитед Кристаллическое производное бензимидазола
WO2010039885A2 (en) * 2008-09-30 2010-04-08 Teva Pharmaceutical Industries Ltd. Crystalline forms of dexlansoprazole
IT1391776B1 (it) 2008-11-18 2012-01-27 Dipharma Francis Srl Procedimento per la preparazione di dexlansoprazolo
IT1392813B1 (it) 2009-02-06 2012-03-23 Dipharma Francis Srl Forme cristalline di dexlansoprazolo
US20110009637A1 (en) * 2009-02-10 2011-01-13 Dario Braga Crystals of Dexlansoprazole
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
IT1395118B1 (it) * 2009-07-29 2012-09-05 Dipharma Francis Srl Procedimento per la preparazione di dexlansoprazolo cristallino
WO2011092665A1 (en) * 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited Process for the preparation of crystalline forms of dexlansoprazole
CA2795056C (en) 2010-03-31 2015-03-24 Ranbaxy Laboratories Limited Salts of dexlansoprazole and their preparation
WO2011121548A1 (en) 2010-03-31 2011-10-06 Ranbaxy Laboratories Limited Process for the preparation of dexlansoprazole
BR112013013571A2 (pt) 2010-12-03 2016-10-11 Takeda Pharmaceutical comprimido para a desintegração oral
MX2013007588A (es) 2010-12-27 2013-08-09 Takeda Pharmaceutical Comprimido de desintegracion oral.
WO2012104805A1 (en) 2011-02-01 2012-08-09 Ranbaxy Laboratories Limited Process for the preparation of dexlansoprazole
AU2012274967A1 (en) 2011-06-21 2014-01-23 Sun Pharmaceutical Industries Limited Process for the preparation of dexlansoprazole
CN102234265B (zh) * 2011-08-08 2013-11-20 天津市汉康医药生物技术有限公司 兰索拉唑化合物
JP5925318B2 (ja) 2011-11-30 2016-05-25 武田薬品工業株式会社 有核錠
WO2013140120A1 (en) 2012-03-22 2013-09-26 Cipla Limited Glycerol solvate forms of (r) - 2 - [ [ [3 -methyl -4 (2,2, 2 - trifluoroethoxy) pyridin- 2 - yl] methyl] sulphinyl] - 1h - ben zimidazole
WO2013179194A1 (en) 2012-05-31 2013-12-05 Ranbaxy Laboratories Limited Process for the preparation of crystalline dexlansoprazole
JP6364406B2 (ja) 2013-05-21 2018-07-25 武田薬品工業株式会社 口腔内崩壊錠
DE102014109120B4 (de) 2014-06-30 2017-04-06 Krohne Messtechnik Gmbh Mikrowellenmodul
CN109111430B (zh) * 2017-06-26 2022-09-30 江苏豪森药业集团有限公司 一种右兰索拉唑晶型a及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE504459C2 (sv) 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423968D0 (en) 1994-11-28 1995-01-11 Astra Ab Resolution
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
SE510666C2 (sv) 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
JP3929607B2 (ja) 1997-07-23 2007-06-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピリジン誘導体の製造方法
WO1999038512A1 (en) 1998-01-30 1999-08-05 Sepracor Inc. S-lansoprazole compositions and methods
WO1999038513A1 (en) 1998-01-30 1999-08-05 Sepracor Inc. R-lansoprazole compositions and methods
CN1087739C (zh) 1998-12-28 2002-07-17 中国科学院成都有机化学研究所 光学纯的苯并咪唑类抗消化性溃疡药物的包结拆分制备法
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
ATE298334T1 (de) * 1999-06-30 2005-07-15 Takeda Pharmaceutical Kristalle von lansoprazole
DE60131649T2 (de) * 2000-05-15 2008-10-30 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung eines kristalls
KR20100002278A (ko) * 2000-12-01 2010-01-06 다케다 야쿠힌 고교 가부시키가이샤 (r)- 또는 (s)-란소프라졸의 결정
US20070265335A1 (en) * 2005-11-10 2007-11-15 Wyeth Polymorphs of 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsufonyl)amino]-n-methyl-1-benzofuran-3-carboxamide and methods of making the same

Also Published As

Publication number Publication date
EP1897877A3 (en) 2008-12-10
AU2001256732A1 (en) 2001-11-26
CA2409044A1 (en) 2002-11-14
CN1437592A (zh) 2003-08-20
ES2511774T3 (es) 2014-10-23
EP1293507A4 (en) 2005-09-07
EP1293507A1 (en) 2003-03-19
ES2293988T3 (es) 2008-04-01
CY1107198T1 (el) 2012-11-21
EP1897877A2 (en) 2008-03-12
US7994332B2 (en) 2011-08-09
KR20080067713A (ko) 2008-07-21
US7569696B2 (en) 2009-08-04
CN1803137A (zh) 2006-07-19
EP1293507B1 (en) 2007-11-28
US8212046B2 (en) 2012-07-03
CA2762960A1 (en) 2001-11-22
EP2281821B1 (en) 2014-10-22
CN1280287C (zh) 2006-10-18
US20110257405A1 (en) 2011-10-20
DE60131649D1 (de) 2008-01-10
EP1897877B1 (en) 2014-09-24
US20030153766A1 (en) 2003-08-14
CA2701704C (en) 2011-09-06
DE60131649T2 (de) 2008-10-30
US20100004458A1 (en) 2010-01-07
CA2409044C (en) 2013-02-19
WO2001087874A1 (en) 2001-11-22
KR101035534B1 (ko) 2011-05-23
EP2281821A1 (en) 2011-02-09
KR20090076980A (ko) 2009-07-13
CA2762960C (en) 2014-07-22
ES2521690T3 (es) 2014-11-13
US7169799B2 (en) 2007-01-30
CA2701704A1 (en) 2001-11-22
CN100562318C (zh) 2009-11-25
PT1293507E (pt) 2008-01-16
US20070004779A1 (en) 2007-01-04

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