DK1294720T3 - Non-nukleosid revers transkriptase-inhibitorer - Google Patents

Non-nukleosid revers transkriptase-inhibitorer

Info

Publication number: DK1294720T3
Authority: DK; Denmark
Prior art keywords: reverse transcriptase; transcriptase inhibitors; nucleoside reverse; nucleoside; inhibitors
Prior art date: 2000-06-16

Application number

DK01949124T

Other languages

English (en)

Inventor

Bruno Simoneau

Original Assignee

Boehringer Ingelheim Ca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-16

Filing date

2001-06-14

Publication date

2006-07-31

2001-06-14 Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd

2006-07-31 Application granted granted Critical

2006-07-31 Publication of DK1294720T3 publication Critical patent/DK1294720T3/da

Links

229940042402 non-nucleoside reverse transcriptase inhibitor Drugs 0.000 title 1
239000002726 nonnucleoside reverse transcriptase inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)

DK01949124T 2000-06-16 2001-06-14 Non-nukleosid revers transkriptase-inhibitorer DK1294720T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US21232900P	2000-06-16	2000-06-16
US25663800P	2000-12-18	2000-12-18

Publications (1)

Publication Number	Publication Date
DK1294720T3 true DK1294720T3 (da)	2006-07-31

Family

ID=26907019

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01949124T DK1294720T3 (da)	2000-06-16	2001-06-14	Non-nukleosid revers transkriptase-inhibitorer

Country Status (35)

Country	Link
US (1)	US6420359B1 (da)
EP (1)	EP1294720B1 (da)
JP (1)	JP3923894B2 (da)
KR (1)	KR20030017540A (da)
CN (1)	CN1178939C (da)
AR (1)	AR028958A1 (da)
AT (1)	ATE322492T1 (da)
AU (2)	AU7037001A (da)
BG (1)	BG107348A (da)
BR (1)	BR0102377A (da)
CA (1)	CA2411766C (da)
CZ (1)	CZ20024114A3 (da)
DE (1)	DE60118560T2 (da)
DK (1)	DK1294720T3 (da)
EA (1)	EA005598B1 (da)
EE (1)	EE200200690A (da)
ES (1)	ES2261433T3 (da)
HR (1)	HRP20021003A2 (da)
HU (1)	HUP0301105A2 (da)
IL (1)	IL152819A0 (da)
MX (1)	MXPA02012205A (da)
MY (1)	MY130375A (da)
NO (1)	NO323830B1 (da)
NZ (1)	NZ523549A (da)
PE (1)	PE20020083A1 (da)
PL (1)	PL360370A1 (da)
PT (1)	PT1294720E (da)
SA (1)	SA01220202B1 (da)
SK (1)	SK17722002A3 (da)
TW (1)	TWI270547B (da)
UA (1)	UA74834C2 (da)
UY (1)	UY26767A1 (da)
WO (1)	WO2001096338A1 (da)
YU (1)	YU94202A (da)
ZA (1)	ZA200209807B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6716836B2 (en)	2001-03-22	2004-04-06	Boehringer Ingelheim (Canada) Ltd.	Non-nucleoside reverse transcriptase inhibitors
US6673791B2 (en) *	2001-07-30	2004-01-06	Boehringer Ingelheim (Canada) Ltd.	Non-nucleoside reverse transcriptase inhibitors
US6706706B2 (en) *	2002-03-27	2004-03-16	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US6806265B2 (en) *	2002-05-16	2004-10-19	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US6759533B2 (en) *	2002-06-28	2004-07-06	Boehringer Ingelheim Pharmaceuticals, Inc.	Process and intermediates for making non-nucleoside HIV-1 reverse transcriptase inhibitors
US7642277B2 (en)	2002-12-04	2010-01-05	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US20040152625A1 (en) *	2002-12-16	2004-08-05	Boehringer Ingelheim International Gmbh	Method for improving the pharmacokinetics of an NNRTI
EP1610782A1 (en) *	2003-03-27	2006-01-04	Boehringer Ingelheim International GmbH	Antiviral combination of a dipyridodiazepinone and a further antiretroviral compound
US7309700B2 (en) *	2004-04-02	2007-12-18	Boehringer Ingelheim International Gmbh	Crystalline forms of 5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2′,3′-e] [1,4]diazepin-6-one
US20060025480A1 (en)	2004-08-02	2006-02-02	Boehringer Ingelheim International Gmbh	Benzoic acid derivatives as non nucleoside reverse transcriptase inhibitors
US7151174B2 (en)	2004-11-05	2006-12-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Process for making a non-nucleoside HIV-1 reverse transcriptase inhibitor
US7282583B2 (en) *	2005-12-05	2007-10-16	Boehringer Ingelheim International Gmbh	Process for making 5,11-Dihydro-11-ethyl-5-methyl-8{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-di pyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
EP2085390A1 (en)	2008-01-31	2009-08-05	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors
MX2011010582A (es) *	2009-04-09	2011-10-19	Boehringer Ingelheim Int	Inhibidores de la replicacion del vih.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5366972A (en) *	1989-04-20	1994-11-22	Boehringer Ingelheim Pharmaceuticals, Inc.	5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
US5705499A (en) *	1995-10-06	1998-01-06	Boehringer Ingelheim Pharmaceuticals, Inc.	8-arylalkyl- and 8-arylheteroalkyl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-e! 1!diazepines and their use in the treatment of HIV-1 infection

2001
- 2001-05-30 TW TW090113049A patent/TWI270547B/zh not_active IP Right Cessation
- 2001-06-12 BR BR0102377-2A patent/BR0102377A/pt not_active IP Right Cessation
- 2001-06-12 US US09/879,447 patent/US6420359B1/en not_active Expired - Lifetime
- 2001-06-13 UY UY26767A patent/UY26767A1/es not_active Application Discontinuation
- 2001-06-14 PL PL36037001A patent/PL360370A1/xx not_active Application Discontinuation
- 2001-06-14 DE DE60118560T patent/DE60118560T2/de not_active Expired - Lifetime
- 2001-06-14 IL IL15281901A patent/IL152819A0/xx unknown
- 2001-06-14 MX MXPA02012205A patent/MXPA02012205A/es active IP Right Grant
- 2001-06-14 HR HR20021003A patent/HRP20021003A2/hr not_active Application Discontinuation
- 2001-06-14 HU HU0301105A patent/HUP0301105A2/hu unknown
- 2001-06-14 EE EEP200200690A patent/EE200200690A/xx unknown
- 2001-06-14 NZ NZ523549A patent/NZ523549A/en unknown
- 2001-06-14 CA CA002411766A patent/CA2411766C/en not_active Expired - Fee Related
- 2001-06-14 CN CNB018112692A patent/CN1178939C/zh not_active Expired - Fee Related
- 2001-06-14 SK SK1772-2002A patent/SK17722002A3/sk not_active Application Discontinuation
- 2001-06-14 AU AU7037001A patent/AU7037001A/xx active Pending
- 2001-06-14 CZ CZ20024114A patent/CZ20024114A3/cs unknown
- 2001-06-14 JP JP2002510480A patent/JP3923894B2/ja not_active Expired - Lifetime
- 2001-06-14 PT PT01949124T patent/PT1294720E/pt unknown
- 2001-06-14 DK DK01949124T patent/DK1294720T3/da active
- 2001-06-14 WO PCT/CA2001/000890 patent/WO2001096338A1/en not_active Ceased
- 2001-06-14 UA UA2003010387A patent/UA74834C2/uk unknown
- 2001-06-14 PE PE2001000560A patent/PE20020083A1/es not_active Application Discontinuation
- 2001-06-14 YU YU94202A patent/YU94202A/sh unknown
- 2001-06-14 AT AT01949124T patent/ATE322492T1/de active
- 2001-06-14 ES ES01949124T patent/ES2261433T3/es not_active Expired - Lifetime
- 2001-06-14 EP EP01949124A patent/EP1294720B1/en not_active Expired - Lifetime
- 2001-06-14 EA EA200201255A patent/EA005598B1/ru not_active IP Right Cessation
- 2001-06-14 AU AU2001270370A patent/AU2001270370B2/en not_active Ceased
- 2001-06-14 KR KR1020027017173A patent/KR20030017540A/ko not_active Abandoned
- 2001-06-15 MY MYPI20012820A patent/MY130375A/en unknown
- 2001-06-15 AR ARP010102870A patent/AR028958A1/es unknown
- 2001-07-07 SA SA01220202A patent/SA01220202B1/ar unknown
2002
- 2002-12-03 ZA ZA200209807A patent/ZA200209807B/en unknown
- 2002-12-03 BG BG107348A patent/BG107348A/bg unknown
- 2002-12-05 NO NO20025844A patent/NO323830B1/no unknown

Also Published As

Publication number	Publication date
HRP20021003A2 (en)	2005-02-28
PL360370A1 (en)	2004-09-06
YU94202A (sh)	2005-11-28
PT1294720E (pt)	2006-06-30
JP2004502787A (ja)	2004-01-29
ES2261433T3 (es)	2006-11-16
BR0102377A (pt)	2002-02-19
HK1057558A1 (en)	2004-04-08
MY130375A (en)	2007-06-29
PE20020083A1 (es)	2002-02-28
NO20025844D0 (no)	2002-12-05
JP3923894B2 (ja)	2007-06-06
TWI270547B (en)	2007-01-11
NO20025844L (no)	2002-12-05
WO2001096338A1 (en)	2001-12-20
ZA200209807B (en)	2003-10-16
EA200201255A1 (ru)	2003-06-26
CN1436189A (zh)	2003-08-13
MXPA02012205A (es)	2003-09-10
AU7037001A (en)	2001-12-24
CZ20024114A3 (cs)	2003-04-16
SK17722002A3 (sk)	2003-06-03
AR028958A1 (es)	2003-05-28
US6420359B1 (en)	2002-07-16
EP1294720A1 (en)	2003-03-26
UA74834C2 (en)	2006-02-15
BG107348A (bg)	2004-06-30
NZ523549A (en)	2004-08-27
EA005598B1 (ru)	2005-04-28
EP1294720B1 (en)	2006-04-05
CA2411766A1 (en)	2001-12-20
HUP0301105A2 (hu)	2003-08-28
CN1178939C (zh)	2004-12-08
NO323830B1 (no)	2007-07-09
US20020028807A1 (en)	2002-03-07
IL152819A0 (en)	2003-06-24
ATE322492T1 (de)	2006-04-15
DE60118560T2 (de)	2006-09-28
AU2001270370B2 (en)	2006-08-03
CA2411766C (en)	2006-05-23
DE60118560D1 (de)	2006-05-18
UY26767A1 (es)	2002-01-31
SA01220202B1 (ar)	2006-09-05
EE200200690A (et)	2004-06-15
KR20030017540A (ko)	2003-03-03

Publication	Publication Date	Title
NO20021042D0 (no)	2002-03-01	Benzofenoner som inhibitorer av revers transkriptase
NO20033857L (no)	2003-10-27	Benzofenoner som inhibitorer av revers transkriptase
DE60117597D1 (de)	2006-04-27	Aufweitvorrichtung
IS6668A (is)	2003-01-03	Kolkínólafleiður sem æðamyndunarhemlar
PL378556A1 (pl)	2006-05-02	Nienukleozydowe inhibitory odwrotnej transkryptazy
ATE433451T1 (de)	2009-06-15	Xanthin-phosphodiesteras-v-inhibitoren
NO20030867L (no)	2003-02-25	Hydroksamderivater anvendelig som deacetylaseinhibitorer
NO20024997D0 (no)	2002-10-17	2-guanidino-4-arylkinazoliner som NHE-3-inhibitorer
IL144349A0 (en)	2002-05-23	Non-nucleoside reverse transcriptase inhibitors
NO20025844L (no)	2002-12-05	Ikke-nukleosid revers transkriptase inhibitorer
DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
DK1742908T3 (da)	2010-01-18	Ikke nukleosid revers transkriptase inhibitorer
NO20044104L (no)	2004-12-01	Ikke-nukleoside reverstranskriptase-inhibitorer
AU2003269628A1 (en)	2004-04-08	Non-nucleoside reverse transcriptase inhibitors
DE60118823D1 (de)	2006-05-24	Entspannungsventil
DE50100256D1 (de)	2003-06-26	Polybenzoxazol-vorstufen
ATE276445T1 (de)	2004-10-15	Spreizdübel
IL157543A (en)	2010-11-30	Cyclopropaheterocycles as non-nucleoside reverse transcriptase inhibitors
DE60130961D1 (de)	2007-11-29	Entspannungsventil
NO20030248L (no)	2003-03-17	Tricykliske pyridonforbindelser anvendelige som HIV revers- transkriptase-inhibitorer
EP1306903A4 (en)	2005-02-09	Inverter
DE60132468D1 (de)	2008-03-06	Alen-lanosterol zyklase inhibitoren
EP1326640A4 (en)	2004-12-15	NON-NUCLEOSIDIC REVERSE-TRANSCRIPTASE INHIBITOR AS ANTIRETROVIRAL THERAPY
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
DK1373267T3 (da)	2005-03-29	Non-nucleoside revers transkriptase-inhibitorer