DK1299354T3 - Faktor VIIA hæmmende (thio)urea-derivater, fremstilling og anvendelse deraf - Google Patents

Faktor VIIA hæmmende (thio)urea-derivater, fremstilling og anvendelse deraf

Info

Publication number: DK1299354T3
Authority: DK; Denmark
Prior art keywords: thio; preparation; factor viia; urea derivatives; viia inhibitory
Prior art date: 2000-06-06

Application number

DK01955291T

Other languages

Danish (da)

English (en)

Inventor

Otmar Klingler

Manfred Schudok

Hans-Peter Nestler

Hans Matter

Herman Schreuder

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-06

Filing date

2001-05-26

Publication date

2009-11-16

2001-05-26 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2009-11-16 Application granted granted Critical

2009-11-16 Publication of DK1299354T3 publication Critical patent/DK1299354T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK01955291T 2000-06-06 2001-05-26 Faktor VIIA hæmmende (thio)urea-derivater, fremstilling og anvendelse deraf DK1299354T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00112116A EP1162194A1 (en)	2000-06-06	2000-06-06	Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
PCT/EP2001/006029 WO2001094301A2 (en)	2000-06-06	2001-05-26	Factor viia inhibitory (thio)urea derivatives, their preparation and their use

Publications (1)

Publication Number	Publication Date
DK1299354T3 true DK1299354T3 (da)	2009-11-16

Family

ID=8168926

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01955291T DK1299354T3 (da)	2000-06-06	2001-05-26	Faktor VIIA hæmmende (thio)urea-derivater, fremstilling og anvendelse deraf

Country Status (29)

Country	Link
US (1)	US6743790B2 (pt)
EP (2)	EP1162194A1 (pt)
JP (1)	JP4809570B2 (pt)
KR (1)	KR101011345B1 (pt)
CN (1)	CN1208314C (pt)
AR (1)	AR030936A1 (pt)
AU (2)	AU2001277494B2 (pt)
BR (1)	BR0111264A (pt)
CA (1)	CA2410862C (pt)
CZ (1)	CZ20023963A3 (pt)
DE (1)	DE60139320D1 (pt)
DK (1)	DK1299354T3 (pt)
EE (1)	EE200200617A (pt)
ES (1)	ES2330412T3 (pt)
HR (1)	HRP20020961A2 (pt)
HU (1)	HUP0301631A2 (pt)
IL (2)	IL153220A0 (pt)
MX (1)	MXPA02009789A (pt)
MY (1)	MY129363A (pt)
NO (1)	NO328546B1 (pt)
NZ (1)	NZ522960A (pt)
PL (1)	PL359584A1 (pt)
PT (1)	PT1299354E (pt)
RU (1)	RU2286337C2 (pt)
SK (1)	SK17032002A3 (pt)
TW (1)	TWI283662B (pt)
WO (1)	WO2001094301A2 (pt)
YU (1)	YU89202A (pt)
ZA (1)	ZA200209018B (pt)

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US7183277B2 (en)	2002-04-27	2007-02-27	Merck Patent Gmbh	Carboxylic acid amides
AU2003265398A1 (en) *	2002-08-09	2004-02-25	Transtech Pharma, Inc.	Aryl and heteroaryl compounds and methods to modulate coagulation
WO2004113278A2 (en) *	2003-05-20	2004-12-29	Genentech, Inc.	Acylsulfamide inhibitors of factor viia
CA2525713A1 (en) *	2003-05-20	2004-12-29	Genentech, Inc.	Benzofuran inhibitors of factor viia
US7501538B2 (en) *	2003-08-08	2009-03-10	Transtech Pharma, Inc.	Aryl and heteroaryl compounds, compositions and methods of use
US7544699B2 (en) *	2003-08-08	2009-06-09	Transtech Pharma, Inc.	Aryl and heteroaryl compounds, compositions, and methods of use
US7208601B2 (en) *	2003-08-08	2007-04-24	Mjalli Adnan M M	Aryl and heteroaryl compounds, compositions, and methods of use
WO2006041119A1 (ja) *	2004-10-13	2006-04-20	Eisai R & D Management Co., Ltd.	ヒドラジド誘導体
TW200630337A (en) *	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
JP2008531523A (ja) *	2005-02-24	2008-08-14	ノボノルディスクヘルスケアアクチェンゲゼルシャフト	Ｖｉｉ因子ポリペプチド製剤を安定化する化合物
US20090041747A1 (en) *	2005-02-24	2009-02-12	Novo Nordisk Health Care Ag	Compounds for Stabilizing Factor VII Polypeptide Formulations
EP1856091A1 (en) *	2005-02-24	2007-11-21	Novo Nordisk Health Care AG	Compounds for stabilizing factor vii polypeptide formulations
ES2553160T3 (es)	2005-06-17	2015-12-04	Novo Nordisk Health Care Ag	Reducción y derivatización selectivas de proteínas Factor VII transformadas por ingeniería que comprenden al menos una cisteína no nativa
NZ571441A (en)	2006-03-24	2010-08-27	Eisai R&D Man Co Ltd	Triazolone derivative
WO2007110449A1 (en) *	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
US8791264B2 (en) *	2006-04-13	2014-07-29	Purdue Pharma L.P.	Benzenesulfonamide compounds and their use as blockers of calcium channels
WO2007118854A1 (en) *	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and the use thereof
WO2008124118A1 (en) *	2007-04-09	2008-10-16	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use therof
JPWO2009038157A1 (ja) *	2007-09-21	2011-01-06	エーザイ・アール・アンド・ディー・マネジメント株式会社	２，３−ジヒドロ−イミノイソインドール誘導体
WO2009040659A2 (en) *	2007-09-28	2009-04-02	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
CN106518742B (zh)	2011-10-26	2020-01-21	阿勒根公司	作为甲酰肽受体样-1(fprl-1)受体调节剂的n-脲取代的氨基酸的酰胺衍生物
SG11201406629VA (en) *	2012-04-16	2014-11-27	Allergan Inc	(2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
EP2906236A1 (en) *	2012-10-10	2015-08-19	Novo Nordisk Health Care AG	Liquid pharmaceutical composition of factor vii polypeptide
BR112015021392B1 (pt)	2013-03-06	2021-11-16	Allergan, Inc	Uso de agonistas do receptor de peptídeo formil 2 para tratar doenças dermatológicas
BR122017004254B1 (pt)	2013-03-06	2021-04-13	Allergan, Inc.	Uso de agonistas de receptor de formil peptídeo 2 para tratar doenças inflamatórias oculares

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US5273982A (en) *	1990-03-09	1993-12-28	Hoffmann-La Roche Inc.	Acetic acid derivatives
US5506134A (en)	1990-10-22	1996-04-09	Corvas International, Inc.	Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
WO1992013552A1 (en) *	1991-02-05	1992-08-20	Smithkline Beecham Corporation	Anti-aggregatory peptides containing an aromatic ester or amide
US5833982A (en)	1991-02-28	1998-11-10	Zymogenetics, Inc.	Modified factor VII
US5788965A (en)	1991-02-28	1998-08-04	Novo Nordisk A/S	Modified factor VII
JP3387948B2 (ja) *	1992-12-04	2003-03-17	富山化学工業株式会社	新規なフェニルアラニン誘導体またはその塩
US5314902A (en)	1993-01-27	1994-05-24	Monsanto Company	Urea derivatives useful as platelet aggregation inhibitors
DE4309867A1 (de) *	1993-03-26	1994-09-29	Cassella Ag	Neue Harnstoffderivate, ihre Herstellung und Verwendung
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
GB9313269D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Allophanic acid derivatives
WO1995008550A1 (en) *	1993-09-24	1995-03-30	Abbott Laboratories	Endothelin antagonists
AU7862794A (en) *	1993-10-19	1995-05-08	Sumitomo Pharmaceuticals Company, Limited	2,3-diaminopropionic acid derivative
US5674894A (en) *	1995-05-15	1997-10-07	G.D. Searle & Co.	Amidine derivatives useful as platelet aggregation inhibitors and vasodilators
AU712504B2 (en) *	1996-01-30	1999-11-11	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
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EP0987274A1 (en) *	1998-09-15	2000-03-22	Hoechst Marion Roussel Deutschland GmbH	Factor VIIa Inhibitors

2000
- 2000-06-06 EP EP00112116A patent/EP1162194A1/en not_active Withdrawn
2001
- 2001-05-26 EP EP01955291A patent/EP1299354B1/en not_active Expired - Lifetime
- 2001-05-26 MX MXPA02009789A patent/MXPA02009789A/es active IP Right Grant
- 2001-05-26 JP JP2002501818A patent/JP4809570B2/ja not_active Expired - Fee Related
- 2001-05-26 CA CA002410862A patent/CA2410862C/en not_active Expired - Fee Related
- 2001-05-26 YU YU89202A patent/YU89202A/sh unknown
- 2001-05-26 HR HRP20020961 patent/HRP20020961A2/hr not_active Application Discontinuation
- 2001-05-26 AU AU2001277494A patent/AU2001277494B2/en not_active Ceased
- 2001-05-26 PT PT01955291T patent/PT1299354E/pt unknown
- 2001-05-26 KR KR1020027016691A patent/KR101011345B1/ko not_active Expired - Fee Related
- 2001-05-26 AU AU7749401A patent/AU7749401A/xx active Pending
- 2001-05-26 HU HU0301631A patent/HUP0301631A2/hu unknown
- 2001-05-26 WO PCT/EP2001/006029 patent/WO2001094301A2/en not_active Ceased
- 2001-05-26 BR BR0111264-3A patent/BR0111264A/pt not_active IP Right Cessation
- 2001-05-26 CZ CZ20023963A patent/CZ20023963A3/cs unknown
- 2001-05-26 CN CNB018088309A patent/CN1208314C/zh not_active Expired - Fee Related
- 2001-05-26 DK DK01955291T patent/DK1299354T3/da active
- 2001-05-26 PL PL01359584A patent/PL359584A1/xx not_active Application Discontinuation
- 2001-05-26 IL IL15322001A patent/IL153220A0/xx unknown
- 2001-05-26 EE EEP200200617A patent/EE200200617A/xx unknown
- 2001-05-26 SK SK1703-2002A patent/SK17032002A3/sk not_active Application Discontinuation
- 2001-05-26 ES ES01955291T patent/ES2330412T3/es not_active Expired - Lifetime
- 2001-05-26 DE DE60139320T patent/DE60139320D1/de not_active Expired - Lifetime
- 2001-05-26 RU RU2002135308/04A patent/RU2286337C2/ru not_active IP Right Cessation
- 2001-05-26 NZ NZ522960A patent/NZ522960A/en unknown
- 2001-06-04 TW TW090113412A patent/TWI283662B/zh not_active IP Right Cessation
- 2001-06-04 AR ARP010102657A patent/AR030936A1/es active IP Right Grant
- 2001-06-05 MY MYPI20012631A patent/MY129363A/en unknown
- 2001-06-06 US US09/874,318 patent/US6743790B2/en not_active Expired - Lifetime
2002
- 2002-11-06 ZA ZA200209018A patent/ZA200209018B/en unknown
- 2002-12-02 IL IL153220A patent/IL153220A/en not_active IP Right Cessation
- 2002-12-03 NO NO20025810A patent/NO328546B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO20025810D0 (no)	2002-12-03
YU89202A (sh)	2006-05-25
TWI283662B (en)	2007-07-11
JP2003535844A (ja)	2003-12-02
NO20025810L (no)	2002-12-03
ES2330412T3 (es)	2009-12-10
US6743790B2 (en)	2004-06-01
PL359584A1 (en)	2004-08-23
WO2001094301A2 (en)	2001-12-13
EP1299354B1 (en)	2009-07-22
HRP20020961A2 (en)	2004-12-31
HK1055941A1 (en)	2004-01-30
SK17032002A3 (sk)	2003-05-02
IL153220A0 (en)	2003-07-06
AU2001277494B2 (en)	2006-05-04
EP1299354A2 (en)	2003-04-09
AU7749401A (en)	2001-12-17
IL153220A (en)	2008-11-03
RU2286337C2 (ru)	2006-10-27
DE60139320D1 (de)	2009-09-03
US20020052417A1 (en)	2002-05-02
HUP0301631A2 (hu)	2003-09-29
CA2410862A1 (en)	2001-12-13
WO2001094301A3 (en)	2002-04-04
EE200200617A (et)	2004-04-15
CZ20023963A3 (cs)	2003-03-12
MY129363A (en)	2007-03-30
NO328546B1 (no)	2010-03-15
MXPA02009789A (es)	2003-03-12
CN1427818A (zh)	2003-07-02
AR030936A1 (es)	2003-09-03
EP1162194A1 (en)	2001-12-12
CA2410862C (en)	2009-11-10
KR20030007911A (ko)	2003-01-23
KR101011345B1 (ko)	2011-01-28
JP4809570B2 (ja)	2011-11-09
PT1299354E (pt)	2009-10-01
BR0111264A (pt)	2003-06-17
ZA200209018B (en)	2003-10-08
NZ522960A (en)	2004-05-28
CN1208314C (zh)	2005-06-29

Publication	Publication Date	Title
DK1299354T3 (da)	2009-11-16	Faktor VIIA hæmmende (thio)urea-derivater, fremstilling og anvendelse deraf
NO20021379D0 (no)	2002-03-20	Benzodiazepin-derivater, fremstilling og anvendelse derav
NO20021449D0 (no)	2002-03-22	Substituerte 2-tio-3,5-dicyano-4-aryl-6-aminopyridiner og anvendelse derav
HUP0401335A3 (en)	2005-04-28	Herbicidal pyridylpropynyloxyphenyl derivatives, preparation and use thereof
DK1368349T3 (da)	2007-05-21	Xanthinderivater, deres fremstilling og deres anvendelse som lægemidler
NO20042635L (no)	2004-06-23	5-Sulfanyl-ñH-1,2,4-triazol-derivater og deres anvendelse som medisin
NO20015156L (no)	2001-12-18	5-pyridyl-1,3-azolforbindelser, deres fremstilling og anvendelse
IS6385A (is)	2002-05-15	Ný notkun og nýjar N-asabísýkló-amíð afleiður
DK1250328T3 (da)	2006-10-30	Dihydro-1,3,5-triazin-aminderivater og terapeutisk anvendelse deraf
NO20011956L (no)	2001-04-20	Substituerte fenylderivater, deres fremstilling og anvendelse
NO20014603L (no)	2001-11-26	Tienopyrimidinforbindelser, deres fremstilling og anvendelse
EE200300327A (et)	2003-10-15	Uurea derivaadid, nende valmistamismeetodid, kasutamine ja farmatseutiline kompositsioon
EE200300311A (et)	2003-10-15	Ftalasinoon-piperidinoderivaadid, nende kasutamine ja ravim
DK1095025T3 (da)	2003-04-07	Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler
NO20031838D0 (no)	2003-04-24	Benzokazinonderivater, deres fremstilling og anvendelse
NO20040702L (no)	2004-05-19	Kombinerte preparater som inneholder 1,4-benzotiepin-1,1-dioksidderivater og andre aktive substanser og anvendelsen derav
ATE303388T1 (de)	2005-09-15	Substituierte 2-pyridinyl-6,7,8,9- tetrahydropyrimidoc1,2-aöpyrimidin-4-on- und 7- pyridinyl-2,3-dihydroimidazo-c1,2-aöpyrimidin- 5(1h)onderivate
DK1345900T3 (da)	2007-05-21	Guanidin- og amidinderivater som faktor XA-inhibitorer
IS6420A (is)	2002-06-13	Setnar Fenýl-píperazín afleiður, framleiðsla þeirra og notkun
DK1043307T3 (da)	2003-09-22	3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
DK1417189T3 (da)	2006-05-08	Acylaminothiazolderivater, fremstilling og terapeutisk anvendelse heraf
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