DK1301207T3 - Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin - Google Patents

Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin

Info

Publication number: DK1301207T3
Authority: DK; Denmark
Prior art keywords: sulbactam; ampicillin; compositions; treatment; bacterial infections
Prior art date: 2000-06-30

Application number

DK01952176T

Other languages

English (en)

Inventor

Donald H Batts

Keiichi Hiramatsu

Original Assignee

Pharmacia & Upjohn Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-30

Filing date

2001-06-21

Publication date

2005-10-10

2001-06-21 Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc

2005-10-10 Application granted granted Critical

2005-10-10 Publication of DK1301207T3 publication Critical patent/DK1301207T3/da

Links

208000035143 Bacterial infection Diseases 0.000 title 1
AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 title 1
229960000723 ampicillin Drugs 0.000 title 1
208000022362 bacterial infectious disease Diseases 0.000 title 1
239000000203 mixture Substances 0.000 title 1
-1 oxazolidinone compound Chemical class 0.000 title 1
FKENQMMABCRJMK-RITPCOANSA-N sulbactam Chemical compound O=S1(=O)C(C)(C)[C@H](C(O)=O)N2C(=O)C[C@H]21 FKENQMMABCRJMK-RITPCOANSA-N 0.000 title 1
229960005256 sulbactam Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK01952176T 2000-06-30 2001-06-21 Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin DK1301207T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US21541800P	2000-06-30	2000-06-30
US23277300P	2000-09-15	2000-09-15
US27930601P	2001-03-28	2001-03-28
PCT/US2001/019712 WO2002002095A2 (en)	2000-06-30	2001-06-21	Compositions for treating bacterial infections containing oxazolidinone compound, sulbactam and an ampicillin

Publications (1)

Publication Number	Publication Date
DK1301207T3 true DK1301207T3 (da)	2005-10-10

Family

ID=27396119

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01952176T DK1301207T3 (da)	2000-06-30	2001-06-21	Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin

Country Status (14)

Country	Link
US (1)	US6544991B2 (da)
EP (1)	EP1301207B1 (da)
JP (1)	JP2004501965A (da)
AR (1)	AR029544A1 (da)
AT (1)	ATE301474T1 (da)
AU (1)	AU2001272961A1 (da)
DE (1)	DE60112581T2 (da)
DK (1)	DK1301207T3 (da)
ES (1)	ES2245698T3 (da)
MY (1)	MY128739A (da)
PE (1)	PE20020295A1 (da)
PT (1)	PT1301207E (da)
TW (1)	TWI265030B (da)
WO (1)	WO2002002095A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
GB0009803D0 (en)	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
WO2003030906A1 (en) *	2001-10-11	2003-04-17	Pharmacia & Upjohn Company	Treating infections by administration of oxazolidinones to the skin
PL372661A1 (en) *	2002-03-29	2005-07-25	Pharmacia & Upjohn Company Llc.	Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
AU2003224345A1 (en) *	2002-04-30	2003-11-17	Orchid Chemicals & Pharmaceuticals	Antibacterial agents
KR20080005599A (ko) *	2005-05-06	2008-01-14	와이어쓰	헤파린 존재하에 티게사이클린의 전달
CA2610978A1 (en)	2005-06-29	2007-01-04	Pharmacia & Upjohn Company Llc	Homomorpholine oxazolidinones as antibacterial agents
WO2007086014A1 (en) *	2006-01-25	2007-08-02	Jegannathan Srinivas	Formulation comprising cefpirome, tazobactam and linezolid
WO2007086012A1 (en) *	2006-01-25	2007-08-02	Jegannathan Srinivas	Formulation of cefpodoxime, clavulanic acid and linezolid
WO2007086013A1 (en) *	2006-01-25	2007-08-02	Jegannathan Srinivas	Formulation comprising of ceftazidime, tazobactam and linezolid
WO2007086011A1 (en) *	2006-01-25	2007-08-02	Jegannathan Srinivas	Formulation comprising cefepime, tazobactam and linezolid
WO2008090570A1 (en) *	2007-01-25	2008-07-31	Panacea Biotec Ltd	Novel antimicrobials
CN102224151A (zh)	2008-11-20	2011-10-19	万能药生物有限公司	新的抗微生物剂
RU2012102094A (ru)	2009-06-26	2013-08-10	Панацеа Биотек Лтд.	Новые азабициклогексаны
WO2017066964A1 (en)	2015-10-22	2017-04-27	Merck Sharp & Dohme Corp.	Oxazolidinone compounds and methods of use thereof as antibacterial agents
WO2021184339A1 (en)	2020-03-20	2021-09-23	Merck Sharp & Dohme Corp.	Oxazolidinone compound and methods of use thereof as an antibacterial agent

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB902703A (en)	1960-08-25	1962-08-09	Beecham Res Lab	Penicillins
US2985648A (en)	1958-10-06	1961-05-23	Doyle Frank Peter	Alpha-aminobenzylpenicillins
BE641785A (da)	1962-12-26
US4234579A (en)	1977-06-07	1980-11-18	Pfizer Inc.	Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
SK283420B6 (sk)	1992-05-08	2003-07-01	Pharmacia & Upjohn Company	Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5688792A (en)	1994-08-16	1997-11-18	Pharmacia & Upjohn Company	Substituted oxazine and thiazine oxazolidinone antimicrobials
DE4425613A1 (de)	1994-07-20	1996-01-25	Bayer Ag	5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de)	1994-07-20	1996-04-04	Bayer Ag	6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE19514313A1 (de)	1994-08-03	1996-02-08	Bayer Ag	Benzoxazolyl- und Benzothiazolyloxazolidinone
DE69616366T2 (de)	1995-09-01	2002-07-04	Upjohn Co	Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen
DE19601264A1 (de)	1996-01-16	1997-07-17	Bayer Ag	Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
DE19601265A1 (de)	1996-01-16	1997-07-17	Bayer Ag	2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de)	1996-01-18	1997-07-24	Bayer Ag	Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
US5684024A (en)	1996-01-25	1997-11-04	Viropharma Incorporated	Pyrazole dimers compositions and methods for treating influenza
DE19604223A1 (de)	1996-02-06	1997-08-07	Bayer Ag	Neue substituierte Oxazolidinone
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
SG85683A1 (en)	1996-04-11	2002-01-15	Upjohn Co	Process to prepare oxazolidinones
NZ504372A (en)	1997-11-07	2002-12-20	Upjohn Co	Process to produce N-[3-fluoro-4(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinones
ES2194709T3 (es)	1999-02-01	2003-12-01	Upjohn Co	Procedimiento para preparar carbamatos de tetrahidrotiopiran-o-fluorados.

2001
- 2001-06-21 DE DE60112581T patent/DE60112581T2/de not_active Expired - Fee Related
- 2001-06-21 JP JP2002506717A patent/JP2004501965A/ja active Pending
- 2001-06-21 PT PT01952176T patent/PT1301207E/pt unknown
- 2001-06-21 WO PCT/US2001/019712 patent/WO2002002095A2/en not_active Ceased
- 2001-06-21 ES ES01952176T patent/ES2245698T3/es not_active Expired - Lifetime
- 2001-06-21 AT AT01952176T patent/ATE301474T1/de not_active IP Right Cessation
- 2001-06-21 AU AU2001272961A patent/AU2001272961A1/en not_active Abandoned
- 2001-06-21 DK DK01952176T patent/DK1301207T3/da active
- 2001-06-21 EP EP01952176A patent/EP1301207B1/en not_active Expired - Lifetime
- 2001-06-21 US US09/886,641 patent/US6544991B2/en not_active Expired - Fee Related
- 2001-06-28 PE PE2001000643A patent/PE20020295A1/es not_active Application Discontinuation
- 2001-06-29 MY MYPI20013131A patent/MY128739A/en unknown
- 2001-06-29 TW TW090115958A patent/TWI265030B/zh not_active IP Right Cessation
- 2001-06-29 AR ARP010103125A patent/AR029544A1/es unknown

Also Published As

Publication number	Publication date
MY128739A (en)	2007-02-28
EP1301207B1 (en)	2005-08-10
TWI265030B (en)	2006-11-01
US20020022610A1 (en)	2002-02-21
JP2004501965A (ja)	2004-01-22
EP1301207A2 (en)	2003-04-16
DE60112581D1 (de)	2005-09-15
WO2002002095A3 (en)	2003-02-06
WO2002002095A2 (en)	2002-01-10
PE20020295A1 (es)	2002-04-07
ATE301474T1 (de)	2005-08-15
AR029544A1 (es)	2003-07-02
PT1301207E (pt)	2005-11-30
AU2001272961A1 (en)	2002-01-14
ES2245698T3 (es)	2006-01-16
WO2002002095B1 (en)	2004-03-25
US6544991B2 (en)	2003-04-08
DE60112581T2 (de)	2006-06-01

Publication	Publication Date	Title
GB0125222D0 (en)	2001-12-12	Composition for the treatment of microbial infections
SI1427711T1 (sl)	2005-12-31	Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva
SE0102315D0 (sv)	2001-06-28	Compounds
DK1448234T3 (da)	2008-11-03	Formuleringer, der omfatter en cephalosporinforbindelse, og deres anvendelse til behandling af bakterieinfektioner hos katte og hunde
ATE323487T1 (de)	2006-05-15	Glukokinase beeinflussende verbindungen
DK2128246T3 (da)	2014-05-12	Fremgangsmåder og sammensætninger til fremstilling af ortogonale tRNA-aminoacyl-tRNA-syntetasepar.
WO2003088897A3 (en)	2005-06-09	Fab i inhibitors
DK1562968T3 (da)	2013-10-28	Anti-il-6-antistoffer, sammensætninger, fremgangsmåder og anvendelser
IL158168A0 (en)	2004-03-28	5-membered, nitrogen-containing heterocyclic compounds and pharmaceutical compositions containing the same
NO20025204D0 (no)	2002-10-30	Forbindelser og fremgangsmÕter for behandling og forebygging av bakterielle infeksjoner
DK1183269T3 (da)	2007-04-02	Svækkede mikroorganismer til behandlingen af infektion
ZA200101821B (en)	2002-09-05	Use of heteroaryl substituted n-(indole-2-carbonyl-) amides for treatment of infection.
IL168747A0 (en)	2009-02-11	Oxazolidinone and/or isoxazoline derivatives as antibacterial agents
NO20014314D0 (no)	2001-09-05	Blandinger og metoder for behandling av stafylokokkisk infeksjon
DK1380121T3 (da)	2007-12-27	Fremgangsmåde til fremstilling af oxazolidinoner
PT1301207E (pt)	2005-11-30	Composicoes para o tratamento de infeccoes bacterianas que contem um composto de oxazolidinona, sulbactam e ampicilina
IL159540A0 (en)	2004-06-01	Heterocyclic compounds as selective bacterial dhfr inhibitors and the uses thereof
DK1656143T3 (da)	2012-02-06	Quinolon-antibiotika til behandling af periodontale infektioner
ATE405574T1 (de)	2008-09-15	Aryl-annellierte azapolyzyklische verbindungen
DK1459748T3 (da)	2005-07-04	(S,S)-reboxetin til behandling af perifer neuropati
ITTO20020747A1 (it)	2003-02-25	Composizione.
SI1301207T1 (sl)	2005-12-31	Sestavki za zdravljenje bakterijskih infekcij, ki vsebujejo oksazolidinonsko spojino, sulbaktam in ampicilin
ITTO20020745A1 (it)	2003-02-25	Composizione.
IL160490A0 (en)	2004-07-25	Systematical administration of some oxazolidinones, e.g. linezolid, for the treatment for ocular infections
DK1105101T3 (da)	2005-02-28	Fremgangsmåder og præparater til behandling af intracellulære infektioner