DK1305014T3 - Anvendelse af (deaminohydroxy)toremifen til behandling af vaginal törhed eller seksuel dysfunktion hos kvinder under eller efter menopausen - Google Patents

Anvendelse af (deaminohydroxy)toremifen til behandling af vaginal törhed eller seksuel dysfunktion hos kvinder under eller efter menopausen

Info

Publication number: DK1305014T3
Authority: DK; Denmark
Prior art keywords: treatment; deaminohydroxy; menopause; toremifene; sexual dysfunction
Prior art date: 2000-07-21

Application number

DK01931746T

Other languages

English (en)

Inventor

Kaija Halonen

Lauri Kangas

Michael W Degregorio

Original Assignee

Hormos Medical Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-21

Filing date

2001-05-02

Publication date

2005-08-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24504996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1305014(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-05-02 Application filed by Hormos Medical Corp filed Critical Hormos Medical Corp

2005-08-22 Application granted granted Critical

2005-08-22 Publication of DK1305014T3 publication Critical patent/DK1305014T3/da

Links

201000001880 Sexual dysfunction Diseases 0.000 title 1
206010047791 Vulvovaginal dryness Diseases 0.000 title 1
230000009245 menopause Effects 0.000 title 1
LUMKNAVTFCDUIE-VHXPQNKSSA-N ospemifene Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-VHXPQNKSSA-N 0.000 title 1
231100000872 sexual dysfunction Toxicity 0.000 title 1
206010003694 Atrophy Diseases 0.000 abstract 1
206010067994 Mucosal atrophy Diseases 0.000 abstract 1
206010040799 Skin atrophy Diseases 0.000 abstract 1
230000037444 atrophy Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
239000002207 metabolite Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK01931746T 2000-07-21 2001-05-02 Anvendelse af (deaminohydroxy)toremifen til behandling af vaginal törhed eller seksuel dysfunktion hos kvinder under eller efter menopausen DK1305014T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/625,199 US6245819B1 (en)	2000-07-21	2000-07-21	Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
PCT/FI2001/000414 WO2002007718A1 (en)	2000-07-21	2001-05-02	Method for the treatment of climacteric disorders in women during or after the menopause

Publications (1)

Publication Number	Publication Date
DK1305014T3 true DK1305014T3 (da)	2005-08-22

Family

ID=24504996

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01931746T DK1305014T3 (da)	2000-07-21	2001-05-02	Anvendelse af (deaminohydroxy)toremifen til behandling af vaginal törhed eller seksuel dysfunktion hos kvinder under eller efter menopausen

Country Status (30)

Country	Link
US (5)	US6245819B1 (da)
EP (1)	EP1305014B1 (da)
JP (2)	JP5575351B2 (da)
KR (1)	KR100880564B1 (da)
CN (1)	CN1287775C (da)
AT (1)	ATE300289T1 (da)
AU (2)	AU2001258449B2 (da)
BG (1)	BG65943B1 (da)
BR (1)	BR0112659A (da)
CA (1)	CA2416480C (da)
CY (1)	CY1105370T1 (da)
CZ (1)	CZ299439B6 (da)
DE (1)	DE60112301T2 (da)
DK (1)	DK1305014T3 (da)
EE (1)	EE05344B1 (da)
ES (1)	ES2241819T3 (da)
HR (1)	HRP20030024A2 (da)
HU (1)	HU229361B1 (da)
IL (1)	IL153823A (da)
MX (1)	MXPA03000378A (da)
NO (1)	NO329954B1 (da)
NZ (1)	NZ524181A (da)
PL (1)	PL202654B1 (da)
PT (1)	PT1305014E (da)
RU (1)	RU2268035C2 (da)
SI (1)	SI1305014T1 (da)
SK (1)	SK287096B6 (da)
UA (1)	UA74386C2 (da)
WO (1)	WO2002007718A1 (da)
ZA (1)	ZA200300342B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL120266A (en) *	1996-02-28	2005-05-17	Pfizer	Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
US20020013327A1 (en) *	2000-04-18	2002-01-31	Lee Andrew G.	Compositions and methods for treating female sexual dysfunction
AU2001261244B2 (en) *	2000-05-09	2006-08-03	Nitromed, Inc.	Infrared thermography and methods of use
US6245819B1 (en) *	2000-07-21	2001-06-12	Hormos Medical Oy, Ltd.	Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
CN100448437C (zh) *	2002-06-06	2009-01-07	霍尔莫斯医疗有限公司	抑制女性萎缩或治疗或预防与女性萎缩相关的症状的方法
JP2006515276A (ja) *	2002-10-22	2006-05-25	オスコテック株式会社	骨粗鬆症の予防及び治療効果を有するフラン誘導体並びにこれを含む薬学的組成物
US20040248989A1 (en)	2003-06-05	2004-12-09	Risto Santti	Method for the treatment or prevention of lower urinary tract symptoms
US8236861B2 (en)	2004-02-13	2012-08-07	Hormos Medical Corporation	Method for enhancing the bioavailablity of ospemifene
US20050187302A1 (en) *	2004-02-23	2005-08-25	Hormos Medical Corporation	Method for treatment or prevention of osteoporosis in individuals with high bone turnover
US8642079B2 (en)	2004-02-23	2014-02-04	Hormos Medical Corporation	Solid formulations of ospemifene
CA2565134C (en)	2004-05-04	2013-05-21	Veli-Matti Lehtola	Novel oral formulations of ospemifene
KR100734942B1 (ko)	2007-01-02	2007-07-03	김재현	여성 갱년기 증후군에 유효한 건강기능식품 조성물
EP2121553B1 (en) *	2007-02-14	2012-06-27	Hormos Medical Ltd.	Method for the preparation of therapeutically valuable triphenylbutene derivatives
WO2008099060A2 (en) *	2007-02-14	2008-08-21	Hormos Medical Ltd	Methods for the preparation of fispemifene from ospemifene
US20080293683A1 (en) *	2007-05-24	2008-11-27	University Of Kansas Medical Center	Hormone Replacement Therapy
RU2535112C2 (ru) *	2012-09-19	2014-12-10	Государственное бюджетное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия министерства здравоохранения и социального развития"	Способ лечения климактерических и урогенитальных расстройств у женщин в постменопаузе на фоне гипотириоза
US9321712B2 (en)	2012-10-19	2016-04-26	Fermion Oy	Process for the preparation of ospemifene
MX2017011469A (es)	2015-03-10	2018-01-23	Shionogi Inc	Dispersiones sólidas.
WO2016149675A1 (en) *	2015-03-19	2016-09-22	Epstein Wendy Anne	Compounds and forms of treatment for female sexual disorders
RU2636619C1 (ru) *	2017-02-20	2017-11-24	Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации	Способ лечения вагинальной атрофии у женщин в постменопаузе с учетом состояния эпителия и микробиоценоза влагалища

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5352699A (en)	1992-04-30	1994-10-04	University Of Massachusetts Medical Center	Use of retinioc acid to treat vaginal atrophy
US5461064A (en)	1993-12-21	1995-10-24	Eli Lilly And Company	Methods of inhibiting atrophy of the skin and vagina
GB9418067D0 (en)	1994-09-07	1994-10-26	Orion Yhtymae Oy	Triphenylethylenes for the prevention and treatment of osteoporosis
US5747059A (en)	1996-01-11	1998-05-05	Novo Nordisk A/S	Atrophy of skin/mucous membrane
GB9604577D0 (en)	1996-03-04	1996-05-01	Orion Yhtymae Oy	Serum cholesterol lowering agent
CO5271697A1 (es) *	2000-01-12	2003-04-30	Pfizer Prod Inc	Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona
RU2342145C2 (ru)	2000-01-28	2008-12-27	Андорешерш, Инк.	Селективные модуляторы рецептора эстрогена в комбинации с эстрогенами
US20010034340A1 (en)	2000-03-20	2001-10-25	American Home Products Corporation	Hormone replacement therapy
US6245819B1 (en) *	2000-07-21	2001-06-12	Hormos Medical Oy, Ltd.	Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause

2000
- 2000-07-21 US US09/625,199 patent/US6245819B1/en not_active Expired - Lifetime
2001
- 2001-02-05 UA UA2003021522A patent/UA74386C2/uk unknown
- 2001-05-02 HR HR20030024A patent/HRP20030024A2/xx not_active Application Discontinuation
- 2001-05-02 WO PCT/FI2001/000414 patent/WO2002007718A1/en not_active Ceased
- 2001-05-02 AT AT01931746T patent/ATE300289T1/de active
- 2001-05-02 DE DE60112301T patent/DE60112301T2/de not_active Expired - Lifetime
- 2001-05-02 EE EEP200300031A patent/EE05344B1/xx unknown
- 2001-05-02 CZ CZ20030026A patent/CZ299439B6/cs not_active IP Right Cessation
- 2001-05-02 CA CA002416480A patent/CA2416480C/en not_active Expired - Lifetime
- 2001-05-02 KR KR1020027015576A patent/KR100880564B1/ko not_active Expired - Lifetime
- 2001-05-02 DK DK01931746T patent/DK1305014T3/da active
- 2001-05-02 CN CNB018130194A patent/CN1287775C/zh not_active Expired - Lifetime
- 2001-05-02 IL IL153823A patent/IL153823A/en active IP Right Grant
- 2001-05-02 SI SI200130410T patent/SI1305014T1/sl unknown
- 2001-05-02 EP EP01931746A patent/EP1305014B1/en not_active Expired - Lifetime
- 2001-05-02 ES ES01931746T patent/ES2241819T3/es not_active Expired - Lifetime
- 2001-05-02 JP JP2002513454A patent/JP5575351B2/ja not_active Expired - Lifetime
- 2001-05-02 PL PL359506A patent/PL202654B1/pl unknown
- 2001-05-02 AU AU2001258449A patent/AU2001258449B2/en not_active Expired
- 2001-05-02 MX MXPA03000378A patent/MXPA03000378A/es active IP Right Grant
- 2001-05-02 PT PT01931746T patent/PT1305014E/pt unknown
- 2001-05-02 SK SK1607-2002A patent/SK287096B6/sk not_active IP Right Cessation
- 2001-05-02 HU HU0301791A patent/HU229361B1/hu unknown
- 2001-05-02 RU RU2003105159/14A patent/RU2268035C2/ru active
- 2001-05-02 BR BR0112659-8A patent/BR0112659A/pt not_active Application Discontinuation
- 2001-05-02 AU AU5844901A patent/AU5844901A/xx active Pending
- 2001-05-02 NZ NZ524181A patent/NZ524181A/en not_active IP Right Cessation
2002
- 2002-06-06 US US10/162,708 patent/US6984665B2/en not_active Expired - Lifetime
2003
- 2003-01-13 ZA ZA200300342A patent/ZA200300342B/en unknown
- 2003-01-17 BG BG107472A patent/BG65943B1/bg unknown
- 2003-01-20 NO NO20030273A patent/NO329954B1/no not_active IP Right Cessation
2005
- 2005-08-11 US US11/201,098 patent/US20050272825A1/en not_active Abandoned
- 2005-10-26 CY CY20051101313T patent/CY1105370T1/el unknown
2010
- 2010-07-15 US US12/837,292 patent/US9566252B2/en not_active Expired - Fee Related
2012
- 2012-10-25 JP JP2012235543A patent/JP5629746B2/ja not_active Expired - Lifetime
2014
- 2014-01-24 US US14/163,757 patent/US20140142195A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20030036566A1 (en)	2003-02-20
PT1305014E (pt)	2005-09-30
CA2416480A1 (en)	2002-01-31
WO2002007718A8 (en)	2002-11-14
KR100880564B1 (ko)	2009-01-30
NO20030273D0 (no)	2003-01-20
IL153823A0 (en)	2003-07-31
WO2002007718A1 (en)	2002-01-31
US6245819B1 (en)	2001-06-12
EP1305014B1 (en)	2005-07-27
US6984665B2 (en)	2006-01-10
BG107472A (bg)	2003-11-28
CZ200326A3 (cs)	2003-05-14
KR20030048378A (ko)	2003-06-19
UA74386C2 (uk)	2005-12-15
HUP0301791A3 (en)	2008-01-28
PL202654B1 (pl)	2009-07-31
US20100280131A1 (en)	2010-11-04
AU5844901A (en)	2002-02-05
US9566252B2 (en)	2017-02-14
JP2004504345A (ja)	2004-02-12
ES2241819T3 (es)	2005-11-01
ATE300289T1 (de)	2005-08-15
NZ524181A (en)	2003-07-25
CN1446085A (zh)	2003-10-01
US20140142195A1 (en)	2014-05-22
HU229361B1 (en)	2013-11-28
DE60112301T2 (de)	2006-05-24
CY1105370T1 (el)	2010-04-28
RU2268035C2 (ru)	2006-01-20
NO329954B1 (no)	2011-01-31
US20050272825A1 (en)	2005-12-08
DE60112301D1 (de)	2005-09-01
MXPA03000378A (es)	2003-09-22
PL359506A1 (en)	2004-08-23
AU2001258449B2 (en)	2004-07-29
CZ299439B6 (cs)	2008-07-30
SK287096B6 (sk)	2009-12-07
ZA200300342B (en)	2004-02-13
HRP20030024A2 (en)	2006-12-31
SI1305014T1 (sl)	2005-12-31
JP5629746B2 (ja)	2014-11-26
EP1305014A1 (en)	2003-05-02
HUP0301791A2 (hu)	2003-12-29
BG65943B1 (bg)	2010-06-30
EE05344B1 (et)	2010-10-15
IL153823A (en)	2008-03-20
CN1287775C (zh)	2006-12-06
JP2013060445A (ja)	2013-04-04
SK16072002A3 (sk)	2003-06-03
JP5575351B2 (ja)	2014-08-20
EE200300031A (et)	2004-10-15
BR0112659A (pt)	2003-06-24
CA2416480C (en)	2009-12-08
HK1056694A1 (en)	2004-02-27
NO20030273L (no)	2003-01-20

Publication	Publication Date	Title
EE05344B1 (et)	2010-10-15	Ühendi (deaminohüdroksü)toremifeeni kasutamine tupekuivuse v?i seksuaaldüsfunktsiooni ravis menopausi ajal v?i järel
ECSP045069A (es)	2004-05-28	Uso de flibanserina en el tratamiento de trastornos sexuales
RU2003105159A (ru)	2004-08-27	Способ лечения климактерических расстройств у женщин во время или после менопаузы
DK1578427T3 (da)	2009-06-29	Anvendelse af GnRH-agonister til understötning af den luteale fase ved infertilitetsbehandling
EA200201000A1 (ru)	2003-02-27	Гормон-заместительная терапия
TNSN07147A1 (fr)	2008-11-21	Sex steroid precursors alone or in combination with a selective estrogen receptor modulator and/or with estrogens and/or a type 5 cgmp phosphodiesterase inhibitor for the prevention and treatment of vaginal dryness and sexual dysfunction in postmenopausal women
BRPI0509086A (pt)	2007-08-21	uso de inibidores de pde iii para redução do tamanho do coração em mamìferos sofrendo de parada cardìaca
UY28860A1 (es)	2005-11-30	Procedimiento para el tratamiento de trastornos premenstruales y otros trastornos sexuales femeninos
BRPI0507661A (pt)	2007-07-17	método para aumentar a biodisponibilidade de um composto terapeuticamente ativo, e, uso de um composto ativo
BR0317555A (pt)	2005-11-22	Composições farmacêuticas de sertaconazol para uso vaginal
IL164528A (en)	2010-06-30	Method for inhibition of atrophy or for treatment or prevention of atrophy related symptoms in women
MX2022011242A (es)	2022-12-15	Inmunomodulación de o-het/aril azálidos.
RU2006133903A (ru)	2008-03-27	Способ лечения или профилактики остеопороза у индивидуумов с высоким обменом костной ткани
BRPI0416202A (pt)	2006-12-26	formulações inibidoras de fosfodiesterase v
MX2024002892A (es)	2024-04-05	Azalidos inmunomoduladores.
AR044095A1 (es)	2005-08-24	Composicion farmaceutica que comprende un antagonista del receptor de la hormona del crecimiento y un antihipertensivo y uso de los mismos para prepararla
CL2008002362A1 (es)	2009-04-13	Composicion farmaceutica vaginal que comprende menor igual que 13 mg de dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-en-3beta, 17 beta-diol o 4androsten-3, 17-diona y un excipiente; kit; uso para tratar sintomas menopausicos como incontinencia urinaria, vaginitis atrofica, sequedad vaginal, dispareunia y disfuncion sexual.
UY27115A1 (es)	2002-08-30	Uso de gestágenos para inhibir la maduración acelerada del endometrio durante el tratamiento de la infertilidad