DK1308507T3 - Monoklonalt antistof mod HCV-kerneantigen - Google Patents

Monoklonalt antistof mod HCV-kerneantigen

Info

Publication number
DK1308507T3
DK1308507T3 DK02257622T DK02257622T DK1308507T3 DK 1308507 T3 DK1308507 T3 DK 1308507T3 DK 02257622 T DK02257622 T DK 02257622T DK 02257622 T DK02257622 T DK 02257622T DK 1308507 T3 DK1308507 T3 DK 1308507T3
Authority
DK
Denmark
Prior art keywords
core antigen
hcv core
monoclonal antibody
antibodies
hcv
Prior art date
Application number
DK02257622T
Other languages
English (en)
Inventor
Chander Bahl
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of DK1308507T3 publication Critical patent/DK1308507T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02257622T 2001-11-05 2002-11-04 Monoklonalt antistof mod HCV-kerneantigen DK1308507T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33745301P 2001-11-05 2001-11-05
US10/268,561 US7049060B2 (en) 2001-11-05 2002-10-10 HCV anti-core monoclonal antibodies

Publications (1)

Publication Number Publication Date
DK1308507T3 true DK1308507T3 (da) 2008-05-19

Family

ID=26953173

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02257622T DK1308507T3 (da) 2001-11-05 2002-11-04 Monoklonalt antistof mod HCV-kerneantigen
DK07075928.7T DK1881064T3 (da) 2001-11-05 2002-11-04 HCV-anti-kerne monoklonalt antistof

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07075928.7T DK1881064T3 (da) 2001-11-05 2002-11-04 HCV-anti-kerne monoklonalt antistof

Country Status (9)

Country Link
US (1) US7049060B2 (da)
EP (3) EP1308507B1 (da)
JP (1) JP2004035534A (da)
AT (2) ATE382683T1 (da)
CA (1) CA2406240C (da)
DE (2) DE60224346T2 (da)
DK (2) DK1308507T3 (da)
ES (2) ES2295292T3 (da)
PT (2) PT1881064E (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
JP2009018990A (ja) * 2005-10-25 2009-01-29 Univ Kurume Ｃ型肝炎ウイルス由来ペプチド
US7858752B2 (en) 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
EP3243527B1 (en) 2009-02-13 2019-06-05 Immunomedics, Inc. Immunoconjugates with an intracellularly-cleavable linkage
CA2774260C (en) 2009-09-16 2018-10-09 Immunomedics, Inc. Class i anti-cea antibodies and uses thereof
EP2506881B1 (en) 2009-12-02 2024-03-06 Immunomedics, Inc. Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
AU2012250924B2 (en) 2011-05-02 2017-05-25 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
WO2014028560A2 (en) 2012-08-14 2014-02-20 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
WO2017004144A1 (en) 2015-07-01 2017-01-05 Immunomedics, Inc. Antibody-sn-38 immunoconjugates with a cl2a linker
AU2013360335B2 (en) 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
EP2970947A4 (en) 2013-03-14 2016-10-12 Abbott Lab RECOMBINANT HCV NS3 ANTIGENS AND THEIR MUTANTS FOR ENHANCED ANTIBODY DETECTION
CN105378099B (zh) * 2013-03-14 2021-05-11 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
JP6505076B2 (ja) 2013-03-14 2019-04-24 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｈｃｖ抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
JP6447933B2 (ja) 2014-02-21 2019-01-09 アイビーシー ファーマスーティカルズ，インコーポレイテッド Ｔｒｏｐ−２発現細胞に対する免疫応答を誘発することによる疾患治療
CA2935748A1 (en) 2014-02-25 2015-09-03 Immunomedics, Inc. Humanized rfb4 anti-cd22 antibody
EP3160504B1 (en) 2014-06-24 2020-09-16 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
SI3204018T1 (sl) 2014-10-07 2021-11-30 Immunomedics, Inc. Neoadjuvantna uporaba konjugatov protitelo-zdravilo
US9797907B2 (en) 2015-04-22 2017-10-24 Immunomedics, Inc. Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
AU2016281622C1 (en) 2015-06-25 2021-11-18 Immunomedics, Inc. Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
CN109154617B (zh) 2016-05-31 2022-08-26 豪夫迈·罗氏有限公司 用于hcv核心抗原的快速检测的预处理方法
CN109154616B (zh) 2016-05-31 2022-07-12 豪夫迈·罗氏有限公司 用于病毒抗原的血清学检测的方法
WO2018141768A1 (en) 2017-02-02 2018-08-09 Roche Diagnostics Gmbh Immunoassay using at least two pegylated analyte-specific binding agents
EP3658171B1 (en) 2017-07-27 2023-08-30 Roche Diagnostics GmbH Multi-epitope fusion protein of an hcv antigen and uses thereof
CN109738648B (zh) * 2018-12-29 2021-09-17 山东莱博生物科技有限公司 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用
EP4342497A1 (en) 2021-05-10 2024-03-27 Kawasaki Institute of Industrial Promotion Antibody having reduced binding affinity for antigen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225068B1 (en) 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
FR2775690B1 (fr) 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
WO2000063444A2 (en) 1999-04-14 2000-10-26 Institut Pasteur Method for detecting hepatitis c virus with hybridomas
SK287694B6 (sk) * 2000-06-15 2011-06-06 Novartis Vaccines & Diagnostics, Inc. Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku
JP4353793B2 (ja) * 2001-06-26 2009-10-28 アボット・ラボラトリーズ Ｈｃｖ抗原とｈｃｖ抗体との同時検出のための方法

Also Published As

Publication number Publication date
EP1881064B1 (en) 2010-03-03
US20030148333A1 (en) 2003-08-07
ES2295292T3 (es) 2008-04-16
EP1308507A2 (en) 2003-05-07
US7049060B2 (en) 2006-05-23
DE60235588D1 (de) 2010-04-15
EP1881064A2 (en) 2008-01-23
EP1881064A3 (en) 2008-04-09
ATE459706T1 (de) 2010-03-15
ATE382683T1 (de) 2008-01-15
CA2406240C (en) 2011-01-04
DK1881064T3 (da) 2010-06-07
ES2339709T3 (es) 2010-05-24
DE60224346D1 (de) 2008-02-14
EP2186884A3 (en) 2010-09-08
JP2004035534A (ja) 2004-02-05
CA2406240A1 (en) 2003-05-05
PT1308507E (pt) 2008-03-31
EP1308507A3 (en) 2003-10-22
EP2186884A2 (en) 2010-05-19
PT1881064E (pt) 2010-03-31
DE60224346T2 (de) 2008-12-24
EP1308507B1 (en) 2008-01-02

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