ATE459706T1 - Monoklonales antikörper gegen das hcv kernantigen - Google Patents

Monoklonales antikörper gegen das hcv kernantigen

Info

Publication number
ATE459706T1
ATE459706T1 AT07075928T AT07075928T ATE459706T1 AT E459706 T1 ATE459706 T1 AT E459706T1 AT 07075928 T AT07075928 T AT 07075928T AT 07075928 T AT07075928 T AT 07075928T AT E459706 T1 ATE459706 T1 AT E459706T1
Authority
AT
Austria
Prior art keywords
core antigen
hcv core
monoclonal antibody
antibody against
antibodies
Prior art date
Application number
AT07075928T
Other languages
English (en)
Inventor
Chander Bahl
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of ATE459706T1 publication Critical patent/ATE459706T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT07075928T 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen ATE459706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33745301P 2001-11-05 2001-11-05
US10/268,561 US7049060B2 (en) 2001-11-05 2002-10-10 HCV anti-core monoclonal antibodies

Publications (1)

Publication Number Publication Date
ATE459706T1 true ATE459706T1 (de) 2010-03-15

Family

ID=26953173

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02257622T ATE382683T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen
AT07075928T ATE459706T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02257622T ATE382683T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Country Status (9)

Country Link
US (1) US7049060B2 (de)
EP (3) EP1881064B1 (de)
JP (1) JP2004035534A (de)
AT (2) ATE382683T1 (de)
CA (1) CA2406240C (de)
DE (2) DE60235588D1 (de)
DK (2) DK1881064T3 (de)
ES (2) ES2295292T3 (de)
PT (2) PT1881064E (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
JP2009018990A (ja) * 2005-10-25 2009-01-29 Univ Kurume Ｃ型肝炎ウイルス由来ペプチド
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
ES2738700T3 (es) 2009-02-13 2020-01-24 Immunomedics Inc Inmunoconjugados con un enlace escindible intracelularmente
EP2478110B1 (de) 2009-09-16 2016-01-06 Immunomedics, Inc. Klasse-i-anti-cea-antikörper und verwendungen davon
CA2782194C (en) 2009-12-02 2018-01-16 Immunomedics, Inc. Combination of radiolabelled antibodies (rait) and antibody-drug conjugates (adc) for treatment of pancreatic cancer
US20120009196A1 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
CN103501825B (zh) 2011-05-02 2017-03-15 免疫医疗公司 用于小体积施用的同种异型选择的抗体的超滤浓缩
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
EP2885002A4 (de) 2012-08-14 2016-04-20 Ibc Pharmaceuticals Inc Umleitung t-zell-bispezifischer antikörper zur behandlung von krankheiten
AU2013360335B2 (en) 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
BR112015023239A8 (pt) 2013-03-14 2018-04-17 Abbott Lab ensaio de combinação de anticorpo-antígeno de hcv e métodos e composições para uso do mesmo
MX2015012824A (es) 2013-03-14 2016-06-24 Abbott Lab Antigenos recombinantes ns3 del vhc y mutantes de los mismos para la deteccion mejorada de anticuerpos.
MX376492B (es) 2013-03-14 2025-03-07 Abbott Lab Anticuerpos monoclonares que se unen al dominio de unión a lípidos de la proteína de la cápside del virus de la hepatitis c (vhc)
EP3107577B1 (de) 2014-02-21 2024-03-20 IBC Pharmaceuticals, Inc. Krankheitstherapie durch induktion einer immunantwort gegen trop-2-exprimierende zellen
CN106029098A (zh) 2014-02-25 2016-10-12 免疫医疗公司 人源化rfb4抗cd22抗体
WO2015200260A1 (en) 2014-06-24 2015-12-30 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
CA2961774C (en) 2014-10-07 2023-05-23 Immunomedics, Inc. Neoadjuvant use of antibody-drug conjugates
US9797907B2 (en) 2015-04-22 2017-10-24 Immunomedics, Inc. Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
JP6980980B2 (ja) 2015-06-25 2021-12-15 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. 抗ｈｌａ‐ｄｒまたは抗ｔｒｏｐ‐２抗体と微小管阻害剤、ｐａｒｐ阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド３‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する
EP3316885B1 (de) 2015-07-01 2021-06-23 Immunomedics, Inc. Antikörper-sn-38-immunkonjugate mit einem cl2a-linker
ES3050636T3 (en) 2016-05-31 2025-12-22 Hoffmann La Roche Method for serological detection of viral antigens
KR102156994B1 (ko) 2016-05-31 2020-09-17 에프. 호프만-라 로슈 아게 Hcv 코어 항원의 신속한 검출을 위한 전처리 방법
WO2018141768A1 (en) 2017-02-02 2018-08-09 Roche Diagnostics Gmbh Immunoassay using at least two pegylated analyte-specific binding agents
CN110996986B (zh) 2017-07-27 2024-07-19 豪夫迈·罗氏有限公司 Hcv抗原的多表位融合蛋白及其用途
CN109738648B (zh) * 2018-12-29 2021-09-17 山东莱博生物科技有限公司 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用
JPWO2022239720A1 (de) 2021-05-10 2022-11-17

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0185373B1 (ko) 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
FR2775690B1 (fr) 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
WO2000063444A2 (en) 1999-04-14 2000-10-26 Institut Pasteur Method for detecting hepatitis c virus with hybridomas
DE60125240T3 (de) * 2000-06-15 2010-10-28 Novartis Vaccines and Diagnostics, Inc., Emeryville Hcv-antigen/antikörper-kombinations-assay
CA2450710C (en) * 2001-06-26 2013-11-26 Abbott Laboratories Methods for the simultaneous detection of hcv antigens and hcv antibodies

Also Published As

Publication number Publication date
CA2406240C (en) 2011-01-04
PT1881064E (pt) 2010-03-31
EP1881064B1 (de) 2010-03-03
EP2186884A3 (de) 2010-09-08
DK1308507T3 (da) 2008-05-19
DK1881064T3 (da) 2010-06-07
ATE382683T1 (de) 2008-01-15
US7049060B2 (en) 2006-05-23
ES2295292T3 (es) 2008-04-16
EP2186884A2 (de) 2010-05-19
US20030148333A1 (en) 2003-08-07
JP2004035534A (ja) 2004-02-05
EP1881064A2 (de) 2008-01-23
EP1881064A3 (de) 2008-04-09
EP1308507B1 (de) 2008-01-02
PT1308507E (pt) 2008-03-31
DE60224346T2 (de) 2008-12-24
EP1308507A3 (de) 2003-10-22
ES2339709T3 (es) 2010-05-24
EP1308507A2 (de) 2003-05-07
DE60235588D1 (de) 2010-04-15
CA2406240A1 (en) 2003-05-05
DE60224346D1 (de) 2008-02-14

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