ATE459706T1 - Monoklonales antikörper gegen das hcv kernantigen - Google Patents

Monoklonales antikörper gegen das hcv kernantigen

Info

Publication number
ATE459706T1
ATE459706T1 AT07075928T AT07075928T ATE459706T1 AT E459706 T1 ATE459706 T1 AT E459706T1 AT 07075928 T AT07075928 T AT 07075928T AT 07075928 T AT07075928 T AT 07075928T AT E459706 T1 ATE459706 T1 AT E459706T1
Authority
AT
Austria
Prior art keywords
core antigen
hcv core
monoclonal antibody
antibody against
antibodies
Prior art date
Application number
AT07075928T
Other languages
English (en)
Inventor
Chander Bahl
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of ATE459706T1 publication Critical patent/ATE459706T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT07075928T 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen ATE459706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33745301P 2001-11-05 2001-11-05
US10/268,561 US7049060B2 (en) 2001-11-05 2002-10-10 HCV anti-core monoclonal antibodies

Publications (1)

Publication Number Publication Date
ATE459706T1 true ATE459706T1 (de) 2010-03-15

Family

ID=26953173

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02257622T ATE382683T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen
AT07075928T ATE459706T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02257622T ATE382683T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Country Status (9)

Country Link
US (1) US7049060B2 (de)
EP (3) EP1308507B1 (de)
JP (1) JP2004035534A (de)
AT (2) ATE382683T1 (de)
CA (1) CA2406240C (de)
DE (2) DE60224346T2 (de)
DK (2) DK1308507T3 (de)
ES (2) ES2295292T3 (de)
PT (2) PT1881064E (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
JP2009018990A (ja) * 2005-10-25 2009-01-29 Univ Kurume Ｃ型肝炎ウイルス由来ペプチド
US7858752B2 (en) 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
EP3243527B1 (de) 2009-02-13 2019-06-05 Immunomedics, Inc. Immunkonjugate mit einem intrazellulär spaltbaren linker
CA2774260C (en) 2009-09-16 2018-10-09 Immunomedics, Inc. Class i anti-cea antibodies and uses thereof
EP2506881B1 (de) 2009-12-02 2024-03-06 Immunomedics, Inc. Kombination aus radioimmuntherapie und antikörper-arznei-konjugaten für verbesserte krebstherapie
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
AU2012250924B2 (en) 2011-05-02 2017-05-25 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
WO2014028560A2 (en) 2012-08-14 2014-02-20 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
WO2017004144A1 (en) 2015-07-01 2017-01-05 Immunomedics, Inc. Antibody-sn-38 immunoconjugates with a cl2a linker
AU2013360335B2 (en) 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
EP2970947A4 (de) 2013-03-14 2016-10-12 Abbott Lab Rekombinante hcv-ns3-antigene und mutanten für den verbesserten nachweis von antikörpern
CN105378099B (zh) * 2013-03-14 2021-05-11 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
JP6505076B2 (ja) 2013-03-14 2019-04-24 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｈｃｖ抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
JP6447933B2 (ja) 2014-02-21 2019-01-09 アイビーシー ファーマスーティカルズ，インコーポレイテッド Ｔｒｏｐ−２発現細胞に対する免疫応答を誘発することによる疾患治療
CA2935748A1 (en) 2014-02-25 2015-09-03 Immunomedics, Inc. Humanized rfb4 anti-cd22 antibody
EP3160504B1 (de) 2014-06-24 2020-09-16 Immunomedics, Inc. Antihistontherapie für vaskuläre nekrose bei schwerer glomerulonephritis
SI3204018T1 (sl) 2014-10-07 2021-11-30 Immunomedics, Inc. Neoadjuvantna uporaba konjugatov protitelo-zdravilo
US9797907B2 (en) 2015-04-22 2017-10-24 Immunomedics, Inc. Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
AU2016281622C1 (en) 2015-06-25 2021-11-18 Immunomedics, Inc. Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
CN109154617B (zh) 2016-05-31 2022-08-26 豪夫迈·罗氏有限公司 用于hcv核心抗原的快速检测的预处理方法
CN109154616B (zh) 2016-05-31 2022-07-12 豪夫迈·罗氏有限公司 用于病毒抗原的血清学检测的方法
WO2018141768A1 (en) 2017-02-02 2018-08-09 Roche Diagnostics Gmbh Immunoassay using at least two pegylated analyte-specific binding agents
EP3658171B1 (de) 2017-07-27 2023-08-30 Roche Diagnostics GmbH Multi-epitop-fusionsprotein eines hcv-antigens und verwendungen davon
CN109738648B (zh) * 2018-12-29 2021-09-17 山东莱博生物科技有限公司 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用
EP4342497A1 (de) 2021-05-10 2024-03-27 Kawasaki Institute of Industrial Promotion Antikörper mit reduzierter bindungsaffinität für antigen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225068B1 (en) 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
FR2775690B1 (fr) 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
WO2000063444A2 (en) 1999-04-14 2000-10-26 Institut Pasteur Method for detecting hepatitis c virus with hybridomas
SK287694B6 (sk) * 2000-06-15 2011-06-06 Novartis Vaccines & Diagnostics, Inc. Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku
JP4353793B2 (ja) * 2001-06-26 2009-10-28 アボット・ラボラトリーズ Ｈｃｖ抗原とｈｃｖ抗体との同時検出のための方法

Also Published As

Publication number Publication date
EP1881064B1 (de) 2010-03-03
US20030148333A1 (en) 2003-08-07
DK1308507T3 (da) 2008-05-19
ES2295292T3 (es) 2008-04-16
EP1308507A2 (de) 2003-05-07
US7049060B2 (en) 2006-05-23
DE60235588D1 (de) 2010-04-15
EP1881064A2 (de) 2008-01-23
EP1881064A3 (de) 2008-04-09
ATE382683T1 (de) 2008-01-15
CA2406240C (en) 2011-01-04
DK1881064T3 (da) 2010-06-07
ES2339709T3 (es) 2010-05-24
DE60224346D1 (de) 2008-02-14
EP2186884A3 (de) 2010-09-08
JP2004035534A (ja) 2004-02-05
CA2406240A1 (en) 2003-05-05
PT1308507E (pt) 2008-03-31
EP1308507A3 (de) 2003-10-22
EP2186884A2 (de) 2010-05-19
PT1881064E (pt) 2010-03-31
DE60224346T2 (de) 2008-12-24
EP1308507B1 (de) 2008-01-02

Similar Documents

Publication Publication Date Title
ATE382683T1 (de) Monoklonales antikörper gegen das hcv kernantigen
DK1716181T3 (da) CDR-reparerede antistoffer
NO2017032I1 (no) bezlotoksumab
WO2003100033A3 (en) ANTI-αvβ6 ANTIBODIES
EP1607404A4 (de) Monoklonaler antikörper und hybridom, das diesen produziert
ATE554107T1 (de) Als therapeutika geeignete monovalente antikörperfragmente
DE60222658D1 (de) Monoklonaler anti-cd-40-antikörper
ATE248192T1 (de) HUMANISIERTE ANTIKÖRPER DIE AN DAS GLEICHE ANTIGEN WIE ANTIKÖRPER NR-LU-13 BINDEN UND DEREN VERWENDUNG IN ßPRETARGETINGß VERFAHREN
ATE520716T1 (de) Humanisierter anti-cd4-antikörper mit immunsuppressiven eigenschaften
GB2383331A (en) Monoclonal antibody DS6 Tumor-associated antigen CA6 and methods of use thereof
ATE480564T1 (de) Monoklonaler anti-mensch-tenascin-antikörper
ATE517340T1 (de) Sätze gegen kurze epitope gerichteter digitaler antikörper sowie diese verwendende verfahren
BR9507594B8 (pt) Anticorpo monoclonal com scfv humanizado, molécula de ácido nucleico recombinante e proteína recombinante.
DE60045870D1 (de) Monoklonaler antikörper, hybridoma, immuntestverfahren und diagnosekit
BR0015872A (pt) Agentes antitrombóticos
DK0840620T3 (da) IL-8-antagonister til behandling af astma
DK1263790T3 (da) Monoklonale antistoffer for den humane LDL-receptor, deres produktionsmetode og anvendelse
FI20020807A0 (fi) Uusia humanisoituja anti-VAP-1 monoklonaalisia vasta-aineita
NO20080409L (no) Fremgangsmater og preparater til malsoking av IFNAR2
FI20011055L (fi) Heveiiniä sitovat monoklonaaliset vasta-aineet
AR037216A1 (es) Anticuerpos monoclonales antinucleares de hcv
EP1483292A4 (de) Mit bakteriellen collagen-bindenden proteinen kreuzreaktive monoklonale antikörper
DE69227776D1 (de) Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden
BR0204612A (pt) Anticorpos monoclonais antinúcleo de hcv
ATE535259T1 (de) Immunogener, monoklonaler antikörper

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1881064

Country of ref document: EP