DK1319651T3 - 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse - Google Patents

2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Info

Publication number
DK1319651T3
DK1319651T3 DK03003623T DK03003623T DK1319651T3 DK 1319651 T3 DK1319651 T3 DK 1319651T3 DK 03003623 T DK03003623 T DK 03003623T DK 03003623 T DK03003623 T DK 03003623T DK 1319651 T3 DK1319651 T3 DK 1319651T3
Authority
DK
Denmark
Prior art keywords
compound
aminopropane
intermediates
synthesis
drug
Prior art date
Application number
DK03003623T
Other languages
Danish (da)
English (en)
Inventor
Kunitomo Adachi
Yoshiyuki Aoki
Tokushi Hanano
Koji Teshima
Yukio Hoshino
Tetsuro Fujita
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Application granted granted Critical
Publication of DK1319651T3 publication Critical patent/DK1319651T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
    • C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK03003623T 1997-04-04 1998-04-03 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse DK1319651T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8625597 1997-04-04
EP98911211A EP1002792B1 (de) 1997-04-04 1998-04-03 2-aminopropan-1,3-diol-verbindungen, ihre medizinische anwendung und zwischenprodukte zu ihrer synthese
PCT/JP1998/001571 WO1998045249A1 (en) 1997-04-04 1998-04-03 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same

Publications (1)

Publication Number Publication Date
DK1319651T3 true DK1319651T3 (da) 2005-08-01

Family

ID=13881722

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03003623T DK1319651T3 (da) 1997-04-04 1998-04-03 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse
DK98911211T DK1002792T3 (da) 1997-04-04 1998-04-03 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK98911211T DK1002792T3 (da) 1997-04-04 1998-04-03 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Country Status (18)

Country Link
US (2) US6214873B1 (de)
EP (2) EP1002792B1 (de)
JP (1) JP4045364B2 (de)
KR (1) KR100551931B1 (de)
CN (2) CN1137086C (de)
AT (2) ATE298740T1 (de)
AU (1) AU735853B2 (de)
BR (1) BR9808481A (de)
CA (1) CA2286315C (de)
DE (2) DE69825056T2 (de)
DK (2) DK1319651T3 (de)
ES (2) ES2240868T3 (de)
IL (3) IL155065A (de)
NZ (1) NZ500713A (de)
PT (2) PT1002792E (de)
RU (1) RU2198162C2 (de)
SI (2) SI1002792T1 (de)
WO (1) WO1998045249A1 (de)

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Also Published As

Publication number Publication date
EP1002792B1 (de) 2004-07-14
CA2286315A1 (en) 1998-10-15
KR100551931B1 (ko) 2006-02-16
PT1319651E (pt) 2005-09-30
AU6523098A (en) 1998-10-30
IL155065A0 (en) 2003-10-31
DK1002792T3 (da) 2004-11-22
CA2286315C (en) 2007-03-06
IL155066A0 (en) 2003-10-31
BR9808481A (pt) 2000-05-23
EP1319651A2 (de) 2003-06-18
CN1290819C (zh) 2006-12-20
US6214873B1 (en) 2001-04-10
EP1002792A4 (de) 2002-03-20
CN1259117A (zh) 2000-07-05
DE69825056D1 (de) 2004-08-19
DE69830756D1 (de) 2005-08-04
PT1002792E (pt) 2004-12-31
CN1137086C (zh) 2004-02-04
IL132208A0 (en) 2001-03-19
USRE39072E1 (en) 2006-04-18
AU735853B2 (en) 2001-07-19
ATE298740T1 (de) 2005-07-15
WO1998045249A1 (en) 1998-10-15
IL155065A (en) 2004-01-04
IL132208A (en) 2003-07-31
KR20010006004A (ko) 2001-01-15
EP1319651B1 (de) 2005-06-29
NZ500713A (en) 2000-07-28
EP1002792A1 (de) 2000-05-24
DE69830756T2 (de) 2006-05-04
EP1319651A3 (de) 2004-01-02
CN1480450A (zh) 2004-03-10
IL155066A (en) 2004-06-20
ES2240868T3 (es) 2005-10-16
SI1002792T1 (en) 2004-12-31
ES2226110T3 (es) 2005-03-16
ATE271028T1 (de) 2004-07-15
RU2198162C2 (ru) 2003-02-10
SI1319651T1 (en) 2005-10-31
DE69825056T2 (de) 2005-08-25
JP4045364B2 (ja) 2008-02-13

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