DK1328546T3 - Cyclopeptider, fremgangsmåde til deres fremstilling og deres anvendelse som angiogenese-inhibitorer eller -aktivatorer - Google Patents

Cyclopeptider, fremgangsmåde til deres fremstilling og deres anvendelse som angiogenese-inhibitorer eller -aktivatorer

Info

Publication number
DK1328546T3
DK1328546T3 DK01974427T DK01974427T DK1328546T3 DK 1328546 T3 DK1328546 T3 DK 1328546T3 DK 01974427 T DK01974427 T DK 01974427T DK 01974427 T DK01974427 T DK 01974427T DK 1328546 T3 DK1328546 T3 DK 1328546T3
Authority
DK
Denmark
Prior art keywords
cyclopeptides
activators
preparation
methods
angiogenesis inhibitors
Prior art date
Application number
DK01974427T
Other languages
Danish (da)
English (en)
Inventor
Natacha Betz
Andreas Bikfalvi
Gerard Deleris
Original Assignee
Commissariat Energie Atomique
Univ Victor Segalen Bordeaux 2
Univ Bordeaux 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Univ Victor Segalen Bordeaux 2, Univ Bordeaux 1 filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of DK1328546T3 publication Critical patent/DK1328546T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK01974427T 2000-10-04 2001-10-02 Cyclopeptider, fremgangsmåde til deres fremstilling og deres anvendelse som angiogenese-inhibitorer eller -aktivatorer DK1328546T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012654A FR2814744B1 (fr) 2000-10-04 2000-10-04 Cyclopeptides, leur procede de preparation et leur utilisation comme inhibiteur ou activateur de l'angiogenese
PCT/FR2001/003049 WO2002028895A2 (fr) 2000-10-04 2001-10-02 Cyclopeptides, leur procede de preparation et leur utilisation comme inhibiteur ou activateur de l'angiogenese

Publications (1)

Publication Number Publication Date
DK1328546T3 true DK1328546T3 (da) 2007-06-04

Family

ID=8854977

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01974427T DK1328546T3 (da) 2000-10-04 2001-10-02 Cyclopeptider, fremgangsmåde til deres fremstilling og deres anvendelse som angiogenese-inhibitorer eller -aktivatorer

Country Status (15)

Country Link
US (2) US7199100B2 (de)
EP (1) EP1328546B1 (de)
JP (1) JP4303958B2 (de)
AT (1) ATE354589T1 (de)
AU (2) AU9394801A (de)
CA (1) CA2424506A1 (de)
DE (1) DE60126802T2 (de)
DK (1) DK1328546T3 (de)
ES (1) ES2282293T3 (de)
FR (1) FR2814744B1 (de)
IL (1) IL155117A0 (de)
NO (1) NO20031377L (de)
NZ (1) NZ525069A (de)
RU (1) RU2249599C2 (de)
WO (1) WO2002028895A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8623822B2 (en) * 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
EP1587944A4 (de) 2002-03-01 2007-03-21 Dyax Corp Kdr und vegf/kdr-bindende peptide und ihre diagnostische und therapeutische veranwendung bei der diagnose und therapie
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US7794693B2 (en) * 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
EP2284180B1 (de) 2003-03-03 2015-09-09 Dyax Corp. Verwendungen von Spezifisch an HGF-Rezeptor (cMET) bindenden Peptiden
DE602007005349D1 (de) * 2006-01-17 2010-04-29 Organon Nv SELEKTIVE ENZYMATISCHE HYDROLYSE VON C-TERMINALEN tert-BUTYL-PEPTIDESTERN
JP5186632B2 (ja) 2006-10-19 2013-04-17 ブリッタ ハーディ， 血管形成を誘導するための組成物および方法
US8741850B2 (en) * 2009-07-24 2014-06-03 Advanced Accelerator Applications S.A. Compounds modulators of VEGF activity and uses thereof
FR2969999B1 (fr) 2011-01-03 2013-02-08 Commissariat Energie Atomique Conjugue, son procede de preparation et ses utilisations
US9815867B2 (en) 2012-09-03 2017-11-14 The University Of Tokyo Peptide for inhibiting vascular endothelial growth factor receptor
CN103724290B (zh) * 2013-11-15 2015-04-29 浙江大学 一种环肽化合物clavatustide A及其产生菌、制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4237456A1 (de) * 1992-11-06 1994-05-11 Merck Patent Gmbh Cyclopeptide
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
EP0844252A3 (de) * 1996-11-15 1998-07-08 Remacle, José Zyklische Peptide mit einer zur anschliessenden chemischen Kupplung entworfenen Zweiggruppe und Verfahren zu deren Herstellung
EP1056773A2 (de) * 1998-02-11 2000-12-06 Resolution Pharmaceuticals Inc. Für angiogenese spezifische moleküle
WO2000053219A2 (en) * 1999-03-11 2000-09-14 Entremed, Inc. Compositions and methods for treating cancer and hyperproliferative disorders

Also Published As

Publication number Publication date
RU2249599C2 (ru) 2005-04-10
FR2814744A1 (fr) 2002-04-05
NZ525069A (en) 2004-09-24
US20040092434A1 (en) 2004-05-13
JP4303958B2 (ja) 2009-07-29
DE60126802T2 (de) 2007-11-08
USRE44022E1 (en) 2013-02-19
IL155117A0 (en) 2003-10-31
NO20031377D0 (no) 2003-03-26
EP1328546A2 (de) 2003-07-23
JP2004510784A (ja) 2004-04-08
AU9394801A (en) 2002-04-15
CA2424506A1 (en) 2002-04-11
ES2282293T3 (es) 2007-10-16
EP1328546B1 (de) 2007-02-21
ATE354589T1 (de) 2007-03-15
NO20031377L (no) 2003-05-02
FR2814744B1 (fr) 2002-11-29
AU2001293948B2 (en) 2005-11-03
WO2002028895A2 (fr) 2002-04-11
WO2002028895A3 (fr) 2002-06-06
US7199100B2 (en) 2007-04-03
DE60126802D1 (de) 2007-04-05

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