DK1328547T3 - Identifikation og modifikation af immundominante epitoper i polypeptider - Google Patents
Identifikation og modifikation af immundominante epitoper i polypeptiderInfo
- Publication number
- DK1328547T3 DK1328547T3 DK01988732.2T DK01988732T DK1328547T3 DK 1328547 T3 DK1328547 T3 DK 1328547T3 DK 01988732 T DK01988732 T DK 01988732T DK 1328547 T3 DK1328547 T3 DK 1328547T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- immunodominant epitopes
- immunodominant
- identification
- modification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24391300P | 2000-10-27 | 2000-10-27 | |
| US09/872,702 US6673580B2 (en) | 2000-10-27 | 2001-06-01 | Identification and modification of immunodominant epitopes in polypeptides |
| PCT/US2001/040846 WO2002034779A1 (en) | 2000-10-27 | 2001-06-04 | Identification and modification of immunodominant epitopes in polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1328547T3 true DK1328547T3 (da) | 2011-10-31 |
Family
ID=26936187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01988732.2T DK1328547T3 (da) | 2000-10-27 | 2001-06-04 | Identifikation og modifikation af immundominante epitoper i polypeptider |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6673580B2 (da) |
| EP (1) | EP1328547B1 (da) |
| AT (1) | ATE520713T1 (da) |
| AU (1) | AU2002245756A1 (da) |
| CA (1) | CA2422953A1 (da) |
| DK (1) | DK1328547T3 (da) |
| WO (1) | WO2002034779A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003276846A1 (en) * | 2002-08-09 | 2004-02-25 | Xencor | Thrombopoiesis-stimulating proteins having reduced immunogenicity |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| WO2004078965A1 (ja) * | 2003-03-05 | 2004-09-16 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 大腸菌における異種蛋白質の製造方法 |
| EP1505080A1 (en) | 2003-07-28 | 2005-02-09 | KRATON Polymers Research B.V. | Method for partially and selectively hydrogenating polymers made of conjugated dienes |
| BRPI0513826A2 (pt) | 2004-07-26 | 2010-06-22 | Dow Global Technologies Inc | processo para expressão de proteìna melhorada através de engenharia de cepa |
| US7597884B2 (en) * | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| WO2006020580A2 (en) * | 2004-08-09 | 2006-02-23 | Alios Biopharma Inc. | Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same |
| WO2006107924A2 (en) | 2005-04-04 | 2006-10-12 | Idexx Laboratories, Inc. | Ehrlichia canis diva (differentiate infected from vaccinated animals) |
| EP1868652A2 (en) * | 2005-04-05 | 2007-12-26 | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. | Method for shielding functional sites or epitopes on proteins |
| EP1792996A1 (en) * | 2005-12-01 | 2007-06-06 | Consejo Superior de Investigaciones Cientificas | Nucleic acid sequences encoding vaccines against Porcine reproductive and respiratory syndrome virus (PRRSV) |
| US7833724B2 (en) * | 2006-03-20 | 2010-11-16 | Teva Women's Health, Inc. | Methods for comparing the immunogenicity of products and uses thereof |
| US9394571B2 (en) | 2007-04-27 | 2016-07-19 | Pfenex Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| EP2215477B1 (en) | 2007-10-31 | 2019-01-16 | IDEXX Laboratories Inc | Ehrlichia canis diva (differentiate infection from vaccinated animals) |
| CN102272151B (zh) * | 2008-11-04 | 2014-08-20 | 詹森药业有限公司 | Crhr2肽激动剂及其用途 |
| WO2011005540A1 (en) | 2009-06-22 | 2011-01-13 | Burnham Institute For Medical Research | Methods and compositions using peptides and proteins with c-terminal elements |
| US20110105397A1 (en) * | 2009-11-04 | 2011-05-05 | Gengo Peter J | Method for treating heart failure with stresscopin-like peptides |
| CN102770456B (zh) | 2009-12-04 | 2018-04-06 | 弗·哈夫曼-拉罗切有限公司 | 多特异性抗体、抗体类似物、组合物和方法 |
| WO2012118778A1 (en) | 2011-02-28 | 2012-09-07 | Sanford-Burnham Medical Research Institute | Truncated car peptides and methods and compositions using truncated car peptides |
| AU2012262488A1 (en) | 2011-05-31 | 2014-01-16 | Airware, Inc. | Re-calibration of AB NDIR gas sensors |
| US10179801B2 (en) | 2011-08-26 | 2019-01-15 | Sanford-Burnham Medical Research Institute | Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides |
| CN110651189B (zh) | 2017-03-03 | 2024-10-25 | 特雷斯生物有限公司 | 肽疫苗 |
| EP3370065A1 (en) | 2017-03-03 | 2018-09-05 | Treos Bio Kft | Immunogenic peptides |
| JP7642530B2 (ja) | 2018-09-04 | 2025-03-10 | トレオス バイオ リミテッド | ペプチドワクチン |
| GB202004974D0 (en) | 2020-04-03 | 2020-05-20 | Treos Bio Ltd | Coronavirus vaccine |
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| DD266710A (da) | ||||
| US3903068A (en) | 1972-12-26 | 1975-09-02 | Us Health Education & Welfare | Facile synthesis of human insulin by modification of porcine insulin |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4657760A (en) | 1979-03-20 | 1987-04-14 | Ortho Pharmaceutical Corporation | Methods and compositions using monoclonal antibody to human T cells |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4943529A (en) | 1982-05-19 | 1990-07-24 | Gist-Brocades Nv | Kluyveromyces as a host strain |
| US4713339A (en) | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
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| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
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| US4946783A (en) | 1987-01-30 | 1990-08-07 | President And Fellows Of Harvard College | Periplasmic protease mutants of Escherichia coli |
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| JPH0714970Y2 (ja) | 1988-12-29 | 1995-04-10 | 株式会社精工舎 | 自動焦点調整装置 |
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| PT831787E (pt) | 1995-06-07 | 2002-02-28 | Alkermes Inc | Composicao para libertacao sustentada da hormona de crescimento humano |
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| JP4562815B2 (ja) | 1997-05-21 | 2010-10-13 | ジェネンテック, インコーポレイテッド | トロンボポエチンの新規な投与 |
| ES2297889T3 (es) * | 1997-07-14 | 2008-05-01 | Bolder Biotechnology, Inc. | Derivados de hormona de crecimiento y proteinas relacionadas. |
| AU743647B2 (en) | 1998-01-31 | 2002-01-31 | Mt. Sinai School Of Medicine Of New York University | Methods and reagents for decreasing allergic reactions |
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| AU776910B2 (en) | 1998-12-08 | 2004-09-23 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Modifying protein immunogenicity |
-
2001
- 2001-06-01 US US09/872,702 patent/US6673580B2/en not_active Expired - Lifetime
- 2001-06-04 WO PCT/US2001/040846 patent/WO2002034779A1/en not_active Ceased
- 2001-06-04 EP EP01988732A patent/EP1328547B1/en not_active Expired - Lifetime
- 2001-06-04 CA CA002422953A patent/CA2422953A1/en not_active Abandoned
- 2001-06-04 AU AU2002245756A patent/AU2002245756A1/en not_active Abandoned
- 2001-06-04 DK DK01988732.2T patent/DK1328547T3/da active
- 2001-06-04 AT AT01988732T patent/ATE520713T1/de not_active IP Right Cessation
-
2003
- 2003-12-08 US US10/731,595 patent/US20040209324A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002245756A1 (en) | 2002-05-06 |
| US20040209324A1 (en) | 2004-10-21 |
| EP1328547B1 (en) | 2011-08-17 |
| EP1328547A1 (en) | 2003-07-23 |
| CA2422953A1 (en) | 2002-05-02 |
| US20030077756A1 (en) | 2003-04-24 |
| US6673580B2 (en) | 2004-01-06 |
| WO2002034779A1 (en) | 2002-05-02 |
| ATE520713T1 (de) | 2011-09-15 |
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