DK1328547T3 - Identifikation og modifikation af immundominante epitoper i polypeptider - Google Patents

Identifikation og modifikation af immundominante epitoper i polypeptider

Info

Publication number
DK1328547T3
DK1328547T3 DK01988732.2T DK01988732T DK1328547T3 DK 1328547 T3 DK1328547 T3 DK 1328547T3 DK 01988732 T DK01988732 T DK 01988732T DK 1328547 T3 DK1328547 T3 DK 1328547T3
Authority
DK
Denmark
Prior art keywords
polypeptides
immunodominant epitopes
immunodominant
identification
modification
Prior art date
Application number
DK01988732.2T
Other languages
English (en)
Inventor
Eugen Koren
John Hok Nin Lowe
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1328547T3 publication Critical patent/DK1328547T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01988732.2T 2000-10-27 2001-06-04 Identifikation og modifikation af immundominante epitoper i polypeptider DK1328547T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24391300P 2000-10-27 2000-10-27
US09/872,702 US6673580B2 (en) 2000-10-27 2001-06-01 Identification and modification of immunodominant epitopes in polypeptides
PCT/US2001/040846 WO2002034779A1 (en) 2000-10-27 2001-06-04 Identification and modification of immunodominant epitopes in polypeptides

Publications (1)

Publication Number Publication Date
DK1328547T3 true DK1328547T3 (da) 2011-10-31

Family

ID=26936187

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01988732.2T DK1328547T3 (da) 2000-10-27 2001-06-04 Identifikation og modifikation af immundominante epitoper i polypeptider

Country Status (7)

Country Link
US (2) US6673580B2 (da)
EP (1) EP1328547B1 (da)
AT (1) ATE520713T1 (da)
AU (1) AU2002245756A1 (da)
CA (1) CA2422953A1 (da)
DK (1) DK1328547T3 (da)
WO (1) WO2002034779A1 (da)

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Also Published As

Publication number Publication date
AU2002245756A1 (en) 2002-05-06
US20030077756A1 (en) 2003-04-24
ATE520713T1 (de) 2011-09-15
EP1328547A1 (en) 2003-07-23
US20040209324A1 (en) 2004-10-21
WO2002034779A1 (en) 2002-05-02
CA2422953A1 (en) 2002-05-02
US6673580B2 (en) 2004-01-06
EP1328547B1 (en) 2011-08-17

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