DK1341753T3 - Cyclohexyl (alkyl) -propanolaminer, deres fremstilling, og farmaceutiske sammensætninger, der indeholder dem - Google Patents

Cyclohexyl (alkyl) -propanolaminer, deres fremstilling, og farmaceutiske sammensætninger, der indeholder dem

Info

Publication number: DK1341753T3
Authority: DK; Denmark
Prior art keywords: propanolamines; cyclohexyl; alkyl; preparation; pharmaceutical compositions
Prior art date: 2000-11-30

Application number

DK01998533T

Other languages

Danish (da)

English (en)

Inventor

Philippe R Bovy

Roberto Cecchi

Gilles Courtemanche

Ambrogio Oliva

Nunzia Viviani

Tiziano Croci

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-30

Filing date

2001-11-30

Publication date

2008-01-14

2001-11-30 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-01-14 Application granted granted Critical

2008-01-14 Publication of DK1341753T3 publication Critical patent/DK1341753T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Obesity (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

DK01998533T 2000-11-30 2001-11-30 Cyclohexyl (alkyl) -propanolaminer, deres fremstilling, og farmaceutiske sammensætninger, der indeholder dem DK1341753T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0015477A FR2817257B1 (fr)	2000-11-30	2000-11-30	Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant
PCT/FR2001/003784 WO2002044139A1 (fr)	2000-11-30	2001-11-30	Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant

Publications (1)

Publication Number	Publication Date
DK1341753T3 true DK1341753T3 (da)	2008-01-14

Family

ID=8857054

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01998533T DK1341753T3 (da)	2000-11-30	2001-11-30	Cyclohexyl (alkyl) -propanolaminer, deres fremstilling, og farmaceutiske sammensætninger, der indeholder dem

Country Status (24)

Country	Link
US (3)	US7388031B2 (de)
EP (1)	EP1341753B1 (de)
JP (1)	JP4024149B2 (de)
CN (2)	CN1935787A (de)
AR (1)	AR031438A1 (de)
AT (1)	ATE374177T1 (de)
AU (2)	AU2207902A (de)
BR (1)	BR0115768A (de)
CA (1)	CA2429267C (de)
CY (1)	CY1106997T1 (de)
CZ (1)	CZ305140B6 (de)
DE (1)	DE60130676T2 (de)
DK (1)	DK1341753T3 (de)
ES (1)	ES2290201T3 (de)
FR (1)	FR2817257B1 (de)
HU (1)	HU229583B1 (de)
ME (1)	MEP23308A (de)
MX (1)	MXPA03004884A (de)
PL (1)	PL206695B1 (de)
PT (1)	PT1341753E (de)
RS (1)	RS51571B (de)
SI (1)	SI1341753T1 (de)
SK (1)	SK287551B6 (de)
WO (1)	WO2002044139A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2817257B1 (fr) *	2000-11-30	2009-03-20	Sanofi Synthelabo	Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant
FR2840301B1 (fr) *	2002-05-29	2007-03-23	Sanofi Synthelabo	Derives de phenyl-cyclohexyl-propanolamine, leur preparation et leur applicaton en therapeutique
FR2840304B1 (fr) *	2002-05-29	2007-05-18	Sanofi Synthelabo	Derives d'oxophenyl-cyclohexyl-propanolamine, leur preparation et leur application en therapeutique
EP2011490A1 (de) *	2007-07-05	2009-01-07	Sanofi-Aventis	Beta-adrenergische Rezeptorligand-Derivate zur Modulierung von Apoptosen
FR2935141B1 (fr) *	2008-08-21	2010-10-08	Sanofi Aventis	Procede de preparation de l'ester ethylique de l'acide 4-[trans-4-[(phenylmethyl)-amino]cyclohexyl]benzoique et de son sel hemifumarate
AU2009308708B2 (en) *	2008-10-31	2015-11-19	Medivation Technologies, Inc.	Azepino [4, 5-b] indoles and methods of use
CN116143575B (zh) *	2023-04-21	2023-06-30	研峰(天津)科学技术应用研究有限公司	昆虫信息素原料3-环己基-1-丙炔合成方法

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US4004028A (en) *	1975-08-06	1977-01-18	Smithkline Corporation	Phenoxypropanolamines
ATE117980T1 (de) *	1988-06-03	1995-02-15	Lilly Co Eli	Serotonin-antagonisten.
US5340838A (en)	1990-05-04	1994-08-23	Eli Lilly And Company	Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
US5096908A (en)	1990-05-04	1992-03-17	Eli Lilly And Company	Method of inhibiting gastric acid secretion
US5258379A (en)	1990-05-04	1993-11-02	Eli Lilly And Company	Method of inhibiting gastric acid secretion with n-arylpiperazines
US5158956A (en)	1990-05-04	1992-10-27	Eli Lilly And Company	Method of inhibiting gastric acid secretion with benzodioxanes
DE4035961A1 (de) *	1990-11-02	1992-05-07	Thomae Gmbh Dr K	Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
AP9300589A0 (en)	1992-11-18	1994-01-31	Smithkline Beecham Corp	Novel 17a and 17b substituted acyl-3-carboxy 3,5-diene steroidal compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-a-reductase.
US5451677A (en) *	1993-02-09	1995-09-19	Merck & Co., Inc.	Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
IL110857A0 (en)	1993-09-09	1994-11-28	Lilly Co Eli	Cessation of tobacco use
CA2134038C (en)	1994-06-16	1997-06-03	David Taiwai Wong	Potentiation of drug response
EP0714663A3 (de)	1994-11-28	1997-01-15	Lilly Co Eli	Potenzierung von Wirkstoffresponz durch Serotonin 1A Rezeptor Antagonisten
US5776959A (en)	1995-06-05	1998-07-07	Washington University	Anticonvulsant and anxiolytic lactam and thiolactam derivatives
TR199800521T1 (xx) *	1995-09-21	1998-06-22	Eli Lilly And Company	Se�imli beta3 adrenerjik agonistler.
EP0792649A1 (de)	1996-02-29	1997-09-03	Eli Lilly And Company	Behandlung von Schlafstörungen
US5958429A (en)	1996-08-16	1999-09-28	Eli Lilly And Company	Potentiation of serotonin response
US20020019440A1 (en)	1996-11-05	2002-02-14	Virbac Sa	Aryloxypropanolamine derivatives, method of preparation and applications thereof
FR2755439B1 (fr)	1996-11-05	1998-12-24	Virbac Sa	Derives aryloxypropanolamines, leur procede de preparation et leurs applications
FR2758460B1 (fr) *	1997-01-21	1999-12-31	Sanofi Sa	Utilisation des agonistes des recepteurs beta-3 adrenergiques pour la preparation de medicaments cicatrisants
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AUPQ841300A0 (en) *	2000-06-27	2000-07-20	Fujisawa Pharmaceutical Co., Ltd.	New aminoalcohol derivatives
EP1303509B1 (de)	2000-07-13	2012-11-28	Eli Lilly And Company	Beta3-adrenorezeptor agonisten
FR2817257B1 (fr)	2000-11-30	2009-03-20	Sanofi Synthelabo	Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant
US6693125B2 (en)	2001-01-24	2004-02-17	Combinatorx Incorporated	Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders
FR2840304B1 (fr) *	2002-05-29	2007-05-18	Sanofi Synthelabo	Derives d'oxophenyl-cyclohexyl-propanolamine, leur preparation et leur application en therapeutique
FR2840301B1 (fr)	2002-05-29	2007-03-23	Sanofi Synthelabo	Derives de phenyl-cyclohexyl-propanolamine, leur preparation et leur applicaton en therapeutique
WO2004006849A2 (en)	2002-07-15	2004-01-22	Combinatorx, Incorporated	Combinations of drugs for the treatment of neoplasms
US20040186131A1 (en)	2002-08-30	2004-09-23	Wathen Michael W	Method of preventing or treating atherosclerosis or restenosis
WO2004076413A2 (en)	2003-02-24	2004-09-10	Arena Pharmaceuticals, Inc.	Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism
CA2558034A1 (en)	2004-03-09	2005-09-22	Elan Pharmaceuticals, Inc.	Substituted hydroxyethylamine aspartyl protease inhibitors

2000
- 2000-11-30 FR FR0015477A patent/FR2817257B1/fr not_active Expired - Fee Related
2001
- 2001-11-29 AR ARP010105555A patent/AR031438A1/es not_active Application Discontinuation
- 2001-11-30 CN CNA2006101518761A patent/CN1935787A/zh active Pending
- 2001-11-30 AT AT01998533T patent/ATE374177T1/de active
- 2001-11-30 PL PL364746A patent/PL206695B1/pl unknown
- 2001-11-30 ME MEP-233/08A patent/MEP23308A/xx unknown
- 2001-11-30 CA CA2429267A patent/CA2429267C/fr not_active Expired - Fee Related
- 2001-11-30 SI SI200130783T patent/SI1341753T1/sl unknown
- 2001-11-30 HU HU0400565A patent/HU229583B1/hu not_active IP Right Cessation
- 2001-11-30 SK SK652-2003A patent/SK287551B6/sk not_active IP Right Cessation
- 2001-11-30 DK DK01998533T patent/DK1341753T3/da active
- 2001-11-30 AU AU2207902A patent/AU2207902A/xx active Pending
- 2001-11-30 US US10/432,493 patent/US7388031B2/en not_active Expired - Lifetime
- 2001-11-30 EP EP01998533A patent/EP1341753B1/de not_active Expired - Lifetime
- 2001-11-30 JP JP2002546509A patent/JP4024149B2/ja not_active Expired - Fee Related
- 2001-11-30 AU AU2002222079A patent/AU2002222079B2/en not_active Ceased
- 2001-11-30 DE DE60130676T patent/DE60130676T2/de not_active Expired - Lifetime
- 2001-11-30 PT PT01998533T patent/PT1341753E/pt unknown
- 2001-11-30 CN CNB018198880A patent/CN1283622C/zh not_active Expired - Fee Related
- 2001-11-30 CZ CZ2003-1499A patent/CZ305140B6/cs not_active IP Right Cessation
- 2001-11-30 WO PCT/FR2001/003784 patent/WO2002044139A1/fr not_active Ceased
- 2001-11-30 BR BR0115768-0A patent/BR0115768A/pt active Search and Examination
- 2001-11-30 RS YU41703A patent/RS51571B/sr unknown
- 2001-11-30 ES ES01998533T patent/ES2290201T3/es not_active Expired - Lifetime
- 2001-11-30 MX MXPA03004884A patent/MXPA03004884A/es active IP Right Grant
2006
- 2006-08-15 US US11/464,537 patent/US7419974B2/en not_active Expired - Lifetime
2007
- 2007-11-08 CY CY20071101450T patent/CY1106997T1/el unknown
2008
- 2008-06-24 US US12/144,843 patent/US7718646B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SK6522003A3 (en)	2003-11-04
HU229583B1 (en)	2014-02-28
CN1935787A (zh)	2007-03-28
CA2429267A1 (fr)	2002-06-06
ATE374177T1 (de)	2007-10-15
CN1478074A (zh)	2004-02-25
HUP0400565A2 (hu)	2004-06-28
EP1341753A1 (de)	2003-09-10
BR0115768A (pt)	2003-12-30
JP4024149B2 (ja)	2007-12-19
US20080261949A1 (en)	2008-10-23
US20040053916A1 (en)	2004-03-18
WO2002044139A1 (fr)	2002-06-06
YU41703A (sh)	2006-05-25
CN1283622C (zh)	2006-11-08
MXPA03004884A (es)	2004-05-04
US7419974B2 (en)	2008-09-02
US7718646B2 (en)	2010-05-18
CZ305140B6 (cs)	2015-05-20
CA2429267C (fr)	2010-09-28
DE60130676D1 (de)	2007-11-08
PT1341753E (pt)	2007-11-13
FR2817257A1 (fr)	2002-05-31
SI1341753T1 (sl)	2007-12-31
US7388031B2 (en)	2008-06-17
RS51571B (sr)	2011-08-31
PL364746A1 (en)	2004-12-13
HUP0400565A3 (en)	2004-08-30
FR2817257B1 (fr)	2009-03-20
HK1055945A1 (zh)	2004-01-30
AU2207902A (en)	2002-06-11
CZ20031499A3 (cs)	2003-08-13
CY1106997T1 (el)	2012-01-25
MEP23308A (en)	2010-06-10
PL206695B1 (pl)	2010-09-30
SK287551B6 (sk)	2011-01-04
AU2002222079B2 (en)	2006-12-14
ES2290201T3 (es)	2008-02-16
JP2004514708A (ja)	2004-05-20
EP1341753B1 (de)	2007-09-26
US20070015745A1 (en)	2007-01-18
AR031438A1 (es)	2003-09-24
DE60130676T2 (de)	2008-07-17

Publication	Publication Date	Title
NO20024175L (no)	2002-10-29	Azetidinderivater, deres fremstilling og farmasöytiske preparater inneholdende forbindelsene
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