DK1345969T3 - Anti-CD28-antistof - Google Patents
Anti-CD28-antistofInfo
- Publication number
- DK1345969T3 DK1345969T3 DK01995797.6T DK01995797T DK1345969T3 DK 1345969 T3 DK1345969 T3 DK 1345969T3 DK 01995797 T DK01995797 T DK 01995797T DK 1345969 T3 DK1345969 T3 DK 1345969T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibody
- receptor
- interaction
- blocks
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0017025 | 2000-12-26 | ||
| PCT/FR2001/004203 WO2002051871A2 (fr) | 2000-12-26 | 2001-12-26 | Anticorps anti-cd28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1345969T3 true DK1345969T3 (da) | 2010-11-29 |
Family
ID=8858197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01995797.6T DK1345969T3 (da) | 2000-12-26 | 2001-12-26 | Anti-CD28-antistof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7723482B2 (da) |
| EP (1) | EP1345969B1 (da) |
| JP (1) | JP4066166B2 (da) |
| AT (1) | ATE477275T1 (da) |
| DE (1) | DE60142794D1 (da) |
| DK (1) | DK1345969T3 (da) |
| ES (1) | ES2353273T3 (da) |
| PT (1) | PT1345969E (da) |
| WO (1) | WO2002051871A2 (da) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080095774A1 (en) * | 2001-02-16 | 2008-04-24 | Wyeth | Agents and Methods for Specifically Blocking CD28-Mediated Signaling |
| US7531168B2 (en) | 2001-02-16 | 2009-05-12 | Genetics Institute Llc | Method for downmodulating immune response in type I diabetes |
| CA2537263C (en) * | 2002-11-27 | 2017-05-30 | Minerva Biotechnologies Corporation | Techniques and compositions for the diagnosis and treatment of cancer (muc1) |
| DK2363410T3 (da) * | 2003-08-26 | 2018-01-15 | Minerva Biotechnologies Corp | Isoformer af muc1 |
| EP2102241A2 (en) | 2006-12-15 | 2009-09-23 | Ablynx N.V. | Amino acid sequences that modulate the interaction between cells of the immune system |
| AR072571A1 (es) * | 2008-07-18 | 2010-09-08 | Bristol Myers Squibb Co | Composiciones monovalentes para union a cd28 y procedimientos de uso |
| NZ592420A (en) | 2008-10-02 | 2012-12-21 | Emergent Product Dev Seattle | Cd86 antagonist multi-target binding proteins |
| EP2210902A1 (en) * | 2009-01-14 | 2010-07-28 | TcL Pharma | Recombinant monovalent antibodies |
| DK2623517T3 (da) | 2009-01-28 | 2015-11-23 | Ind Tech Res Inst | Urin- og serumbiomarkører associeret med diabetisk nefropati |
| FR2951176A1 (fr) | 2009-10-09 | 2011-04-15 | Tcl Pharma | Ligands monovalents du recepteur cd28 humain |
| EP2361935A1 (en) * | 2010-02-18 | 2011-08-31 | TcL Pharma | Anti-CD28 humanized antibodies |
| EP2536764B1 (en) | 2010-02-18 | 2018-07-04 | OSE Immunotherapeutics | Anti-cd28 humanized antibodies |
| WO2012158818A2 (en) | 2011-05-16 | 2012-11-22 | Fabion Pharmaceuticals, Inc. | Multi-specific fab fusion proteins and methods of use |
| EP3091032A1 (en) | 2015-05-08 | 2016-11-09 | Miltenyi Biotec GmbH | Humanized antibody or fragment thereof specific for cd3 |
| CR20180279A (es) | 2015-11-18 | 2018-08-24 | Merck Sharp & Dohme | Enlazadores de ctla4 |
| MA43260A (fr) | 2015-11-18 | 2018-09-26 | Merck Sharp & Dohme | Liants pd1 et/ou lag3 |
| US10544222B2 (en) | 2015-11-18 | 2020-01-28 | Merck Sharp & Dohme Corp. | PD1/CTLA4 binders |
| CN109476756B (zh) | 2016-03-15 | 2022-05-31 | 埃泰美德(香港)有限公司 | 一种多特异性Fab融合蛋白及其用途 |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| US12139534B2 (en) | 2018-03-15 | 2024-11-12 | Biond Biologics Ltd. | Methods and compositions for decreasing soluble immune receptor CD28 |
| CN112638375A (zh) | 2018-06-15 | 2021-04-09 | 旗舰创业创新五公司 | 通过后细胞信号传导因子的调节来增加免疫活性 |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246514A1 (en) | 2018-06-21 | 2019-12-26 | Regeneron Pharmaceuticals, Inc. | Bispecific anti-psma x anti-cd28 antibodies and uses thereof |
| CA3109361A1 (en) | 2018-08-30 | 2020-03-05 | HCW Biologics, Inc. | Single-chain and multi-chain chimeric polypeptides and uses thereof |
| US11401324B2 (en) | 2018-08-30 | 2022-08-02 | HCW Biologics, Inc. | Single-chain chimeric polypeptides and uses thereof |
| US11518792B2 (en) | 2018-08-30 | 2022-12-06 | HCW Biologics, Inc. | Multi-chain chimeric polypeptides and uses thereof |
| EP3847196A4 (en) | 2018-09-07 | 2023-01-04 | ITabMed (HK) Limited | BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF |
| EP3860653A1 (en) | 2018-10-05 | 2021-08-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and systems for controlling the agonistic properties of antibody variable domains by light |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| WO2020132810A1 (en) | 2018-12-24 | 2020-07-02 | Generon (Shanghai) Corporation Ltd. | Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof |
| WO2020183473A1 (en) | 2019-03-14 | 2020-09-17 | Biond Biologics Ltd. | Small shedding blocking agents |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| CN120924491A (zh) | 2019-06-21 | 2025-11-11 | 免疫生物公司 | 多链嵌合多肽和其用途 |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| JP2023509359A (ja) | 2019-12-17 | 2023-03-08 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | 鉄依存性細胞分解の誘導物質との併用抗癌療法 |
| CA3169243A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Methods of activating regulatory t cells |
| AU2021220870A1 (en) | 2020-02-11 | 2022-08-04 | Immunitybio, Inc. | Methods of treating age-related and inflammatory diseases |
| WO2021163299A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Chromatography resin and uses thereof |
| US12589163B2 (en) | 2020-03-12 | 2026-03-31 | Biond Biologics Ltd. | Shedding blocking agents with increased stability |
| CN115836087A (zh) | 2020-04-29 | 2023-03-21 | Hcw生物科技公司 | 抗cd26蛋白及其用途 |
| WO2021247003A1 (en) | 2020-06-01 | 2021-12-09 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| JP2023527869A (ja) | 2020-06-01 | 2023-06-30 | エイチシーダブリュー バイオロジックス インコーポレイテッド | 加齢関連障害の治療法 |
| US12024545B2 (en) | 2020-06-01 | 2024-07-02 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
| CA3192204A1 (en) | 2020-08-19 | 2022-02-24 | Xencor, Inc. | Anti-cd28 and/or anti-b7h3 compositions |
| JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
| EP4320156A1 (en) | 2021-04-09 | 2024-02-14 | Ose Immunotherapeutics | Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains |
| US20240316104A1 (en) | 2021-06-29 | 2024-09-26 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| CN119110809A (zh) | 2022-02-23 | 2024-12-10 | Xencor股份有限公司 | 抗CD28 x抗PSMA抗体 |
| JP2025508939A (ja) | 2022-03-02 | 2025-04-10 | イミュニティーバイオ インコーポレイテッド | 膵臓癌の治療方法 |
| WO2023201311A1 (en) | 2022-04-13 | 2023-10-19 | HCW Biologics, Inc. | Multi-chain chimeric polypeptide for use in the treatment of treating neuroinflammatory disorder |
| US20250249278A1 (en) | 2022-04-14 | 2025-08-07 | Institut National de la Santé et de la Recherche Médicale | Methods for controlling the tumor cell killing by light |
| US12600801B2 (en) | 2022-07-11 | 2026-04-14 | Fred Hutchinson Cancer Center | Single-domain antibodies that bind ROR1 |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| CA3267921A1 (en) | 2022-10-06 | 2024-04-11 | Bicara Therapeutics Inc. | MULTISPECIFIC PROTEINS AND ASSOCIATED PROCESSES |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
| WO2026043906A1 (en) | 2024-08-19 | 2026-02-26 | HCW Biologics, Inc. | Multi-chain chimeric polypeptides and uses thereof |
| US20260049118A1 (en) | 2024-08-19 | 2026-02-19 | HCW Biologics, Inc. | Single-chain chimeric polypeptides and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| ZA91463B (en) | 1990-01-25 | 1992-09-30 | Bristol Myers Squibb Co | Method of activating cytolytic activity of lymphocytes using anti-cd28 antibody |
| WO1994028912A1 (en) | 1993-06-10 | 1994-12-22 | The Regents Of The University Of Michigan | Cd28 pathway immunosuppression |
| US5948893A (en) * | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
-
2001
- 2001-12-26 ES ES01995797T patent/ES2353273T3/es not_active Expired - Lifetime
- 2001-12-26 DK DK01995797.6T patent/DK1345969T3/da active
- 2001-12-26 PT PT01995797T patent/PT1345969E/pt unknown
- 2001-12-26 EP EP01995797A patent/EP1345969B1/fr not_active Expired - Lifetime
- 2001-12-26 US US10/450,832 patent/US7723482B2/en not_active Expired - Lifetime
- 2001-12-26 DE DE60142794T patent/DE60142794D1/de not_active Expired - Lifetime
- 2001-12-26 WO PCT/FR2001/004203 patent/WO2002051871A2/fr not_active Ceased
- 2001-12-26 JP JP2002552964A patent/JP4066166B2/ja not_active Expired - Lifetime
- 2001-12-26 AT AT01995797T patent/ATE477275T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE60142794D1 (de) | 2010-09-23 |
| JP2004516034A (ja) | 2004-06-03 |
| ES2353273T3 (es) | 2011-02-28 |
| EP1345969A2 (fr) | 2003-09-24 |
| EP1345969B1 (fr) | 2010-08-11 |
| WO2002051871A3 (fr) | 2002-08-15 |
| US7723482B2 (en) | 2010-05-25 |
| WO2002051871A2 (fr) | 2002-07-04 |
| PT1345969E (pt) | 2010-11-17 |
| JP4066166B2 (ja) | 2008-03-26 |
| ATE477275T1 (de) | 2010-08-15 |
| US20080038273A1 (en) | 2008-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1345969T3 (da) | Anti-CD28-antistof | |
| CY1119291T1 (el) | Πολυσθενη αντισωματα και χρησεις για αυτα | |
| NO20041325L (no) | Substanser | |
| DE69929235D1 (de) | Spiro-indole als y5-rezeptor antagonisten | |
| IL195338A0 (en) | Optimized fc variants and methods for their generation | |
| GEP20105118B (en) | Anti-vegf antibodies | |
| DE69918946D1 (de) | Rezeptoren für il-18 | |
| NO983431D0 (no) | Anti-kl°emidler | |
| WO1999003822A8 (en) | Bicyclic metabotropic glutamate receptor ligands | |
| WO1998054225A3 (de) | Human-cd28 spezifische monoklonale antikörper zur antigenunspezifischen aktivierung von t-lymphozyten | |
| ZA200407180B (en) | Systems and methods for client-based web crawling. | |
| ES2193102T3 (es) | Compuestos de imidocromo en sistemas catalizadores para la polimerizacion de olefinas. | |
| PT1519748E (pt) | Micropartículas com anticorpos monoclonais específicos de cd28 | |
| TR200001313T2 (tr) | Protein etkileşimlerini ve fonksiyonel ilişkileri kaydeden tarama sistemleri | |
| ATE239126T1 (de) | Siebvorrichtung | |
| DE69738512D1 (de) | Epstein-barr virus type b ctl epitopen | |
| TR200003467T2 (tr) | Neisseria meningitidis antijenik polipeptidler, mütekabil polinükleotidler ve koruyucu antikorlar | |
| BG107046A (en) | Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans | |
| ATE323493T1 (de) | Gesteuerte freisetzung von antidepressiva | |
| ATE221066T1 (de) | Heterozyklische verbindungen | |
| BR9806702A (pt) | Ferramenta para partir discos de freio | |
| WO2000073345A3 (en) | Antibodies specific for mycobacterial polypeptides and uses thereof | |
| TW200607648A (en) | Depositing material on photosensitive material | |
| ES2169161T3 (es) | Metodologia de evaluacion de deposito de la delta-endotoxina del bacillus thuringiensis. | |
| ES1032331Y (es) | Dispositivo de enganche rapido para compas de puertas basculantes. |