|
US20090137416A1
(en)
|
2001-01-16 |
2009-05-28 |
Regeneron Pharmaceuticals, Inc. |
Isolating Cells Expressing Secreted Proteins
|
|
GB0226227D0
(en)
*
|
2002-11-09 |
2002-12-18 |
Avidex Ltd |
Receptors
|
|
DE60327795D1
(de)
|
2002-11-09 |
2009-07-09 |
Immunocore Ltd |
T zell rezeptor "display"
|
|
GB0304068D0
(en)
*
|
2003-02-22 |
2003-03-26 |
Avidex Ltd |
Substances
|
|
US20060047436A1
(en)
*
|
2004-08-25 |
2006-03-02 |
Ishikawa Muriel Y |
System and method for magnifying an immune response
|
|
US20060047435A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to augmenting an immune system
|
|
US20060047434A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to improving an immune system
|
|
US20060047437A1
(en)
*
|
2004-08-25 |
2006-03-02 |
Ishikawa Muriel Y |
System and method for heightening an immune response
|
|
US20060122783A1
(en)
*
|
2004-08-24 |
2006-06-08 |
Ishikawa Muriel Y |
System and method for heightening a humoral immune response
|
|
US20060122784A1
(en)
*
|
2004-12-03 |
2006-06-08 |
Ishikawa Muriel Y |
System and method for augmenting a humoral immune response
|
|
US20060182742A1
(en)
*
|
2004-08-24 |
2006-08-17 |
Ishikawa Muriel Y |
System and method for magnifying a humoral immune response
|
|
US20060095211A1
(en)
*
|
2003-12-05 |
2006-05-04 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
System and method for modulating a cell mediated immune response
|
|
US20060047433A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to enhancing an immune system
|
|
US20060116824A1
(en)
*
|
2004-12-01 |
2006-06-01 |
Ishikawa Muriel Y |
System and method for modulating a humoral immune response
|
|
GB0328363D0
(en)
|
2003-12-06 |
2004-01-14 |
Imp College Innovations Ltd |
Therapeutically useful molecules
|
|
DK1765860T3
(da)
|
2004-05-19 |
2009-03-09 |
Immunocore Ltd |
Ny-ESO-T.cellereceptor med höj affinitet
|
|
GB0411773D0
(en)
*
|
2004-05-26 |
2004-06-30 |
Avidex Ltd |
Method for the identification of polypeptides which bind to a given peptide mhc complex or cd 1-antigen complex
|
|
DK1758935T3
(da)
*
|
2004-05-26 |
2009-08-10 |
Immunocore Ltd |
Telomerase-T-cellereceptorer med höj affinitet
|
|
GB0411771D0
(en)
*
|
2004-05-26 |
2004-06-30 |
Avidex Ltd |
Nucleoproteins displaying native T cell receptor libraries
|
|
AU2005250055B2
(en)
*
|
2004-06-02 |
2008-09-11 |
Adalta Pty Ltd |
Binding moieties based on shark IgNAR domains
|
|
US8361794B2
(en)
|
2004-06-29 |
2013-01-29 |
Immunocore Limited |
Cells expressing a modified T cell receptor
|
|
US20070198196A1
(en)
*
|
2004-08-24 |
2007-08-23 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational systems and methods relating to ameliorating an immune system
|
|
US20060047439A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
System and method for improving a humoral immune response
|
|
US20070196362A1
(en)
*
|
2004-08-24 |
2007-08-23 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems to bolster an immune response
|
|
US20070265818A1
(en)
*
|
2004-08-24 |
2007-11-15 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems for heightening cell-mediated immune response
|
|
US20070207492A1
(en)
*
|
2004-08-24 |
2007-09-06 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems to adjust a humoral immune response
|
|
US20070265819A1
(en)
*
|
2004-08-24 |
2007-11-15 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems for improving cell-mediated immune response
|
|
AU2005291039A1
(en)
*
|
2004-10-01 |
2006-04-13 |
Avidex Ltd. |
T-cell receptors containing a non-native disulfide interchain bond linked to therapeutic agents
|
|
JP2008520227A
(ja)
*
|
2004-11-18 |
2008-06-19 |
メディジーン リミテッド |
可溶性二官能性タンパク質
|
|
GB0425732D0
(en)
*
|
2004-11-23 |
2004-12-22 |
Avidex Ltd |
Gamma-delta t cell receptors
|
|
CN103555733A
(zh)
|
2005-01-05 |
2014-02-05 |
F-星生物技术研究与开发有限公司 |
分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域
|
|
NZ561338A
(en)
*
|
2005-04-01 |
2010-04-30 |
Immunocore Ltd |
High affinity HIV T cell receptors
|
|
GB0524477D0
(en)
*
|
2005-11-30 |
2006-01-11 |
Avidex Ltd |
Isolated T cell receptors which specifically bind to vygfvracl-hla-24
|
|
GB0511124D0
(en)
|
2005-06-01 |
2005-07-06 |
Avidex Ltd |
High affinity melan-a t cell receptors
|
|
KR101441843B1
(ko)
|
2005-10-18 |
2014-09-17 |
내셔날 쥬이쉬 헬스 |
조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및 사용 방법
|
|
US7820174B2
(en)
|
2006-02-24 |
2010-10-26 |
The United States Of America As Represented By The Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
CA2653600A1
(en)
|
2006-05-31 |
2007-12-06 |
The Children's Hospital Of Philadelphia |
Compositions and methods for detection and modulation of t cell mediated immune responses against viral vectors utilized for gene therapy
|
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
|
AT503861B1
(de)
*
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
|
WO2008039818A2
(en)
|
2006-09-26 |
2008-04-03 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified t cell receptors and related materials and methods
|
|
EP3241842B1
(en)
|
2007-06-26 |
2024-01-31 |
F-star Therapeutics Limited |
Display of binding agents
|
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
|
EP2285832B1
(en)
|
2008-05-16 |
2020-08-26 |
Taiga Biotechnologies, Inc. |
Antibodies and processes for preparing the same
|
|
US8450266B2
(en)
*
|
2008-08-07 |
2013-05-28 |
Ipsen Pharma S.A.S. |
Analogues of glucose-dependent insulinotropic polypeptide
|
|
EP2318435B1
(en)
|
2008-08-28 |
2015-12-23 |
Taiga Biotechnologies, Inc. |
Modulators of myc, methods of using the same, and methods of identifying agents that modulate myc
|
|
US8691510B2
(en)
|
2008-11-07 |
2014-04-08 |
Sequenta, Inc. |
Sequence analysis of complex amplicons
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
CN104195227B
(zh)
|
2008-11-07 |
2017-04-12 |
适应生物技术公司 |
通过序列分析监测状况的方法
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
EP2387627B1
(en)
|
2009-01-15 |
2016-03-30 |
Adaptive Biotechnologies Corporation |
Adaptive immunity profiling and methods for generation of monoclonal antibodies
|
|
WO2010088160A1
(en)
|
2009-01-28 |
2010-08-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
GB0908613D0
(en)
*
|
2009-05-20 |
2009-06-24 |
Immunocore Ltd |
T Cell Reseptors
|
|
CN102459643B
(zh)
|
2009-06-25 |
2016-06-01 |
弗雷德哈钦森癌症研究中心 |
检测获得性免疫的方法
|
|
GB0911566D0
(en)
|
2009-07-03 |
2009-08-12 |
Immunocore Ltd |
T cell receptors
|
|
CN102295702B
(zh)
*
|
2011-08-26 |
2014-01-29 |
中国科学院微生物研究所 |
一种针对t细胞受体可变区特异性单抗的制备方法
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
WO2013041865A1
(en)
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
T cell receptors
|
|
EP2768982A4
(en)
|
2011-10-21 |
2015-06-03 |
Adaptive Biotechnologies Corp |
QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS
|
|
LT3424947T
(lt)
|
2011-10-28 |
2021-03-10 |
Regeneron Pharmaceuticals, Inc. |
Genetiškai modifikuotos t ląstelių receptorių pelės
|
|
US9824179B2
(en)
|
2011-12-09 |
2017-11-21 |
Adaptive Biotechnologies Corp. |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
DK2823060T3
(en)
|
2012-03-05 |
2018-05-28 |
Adaptive Biotechnologies Corp |
Determination of associated immune receptor chains from frequency-matched subunits
|
|
CA2872468C
(en)
|
2012-05-08 |
2020-10-27 |
Adaptive Biotechnologies Corporation |
Compositions and methods for measuring and calibrating amplification bias in multiplexed pcr reactions
|
|
JP6378172B2
(ja)
|
2012-05-22 |
2018-08-22 |
アメリカ合衆国 |
マウス抗ny−eso−1t細胞受容体
|
|
JP6285930B2
(ja)
|
2012-07-20 |
2018-02-28 |
タイガ バイオテクノロジーズ,インク. |
造血コンパートメントの再構築及び自家再構築の増進
|
|
AU2013295652B2
(en)
*
|
2012-07-27 |
2018-02-08 |
The Board Of Trustees Of The University Of Illinois |
Engineering T-cell receptors
|
|
JP6449160B2
(ja)
|
2012-10-01 |
2019-01-09 |
アダプティブ バイオテクノロジーズ コーポレイション |
適応免疫受容体多様性およびクローン性特性決定による免疫能力評価関連出願の相互参照
|
|
US10150996B2
(en)
|
2012-10-19 |
2018-12-11 |
Adaptive Biotechnologies Corp. |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
TW202423993A
(zh)
|
2012-11-14 |
2024-06-16 |
美商再生元醫藥公司 |
重組細胞表面捕捉蛋白質
|
|
GB201223172D0
(en)
|
2012-12-21 |
2013-02-06 |
Immunocore Ltd |
Method
|
|
US10272115B2
(en)
|
2013-03-11 |
2019-04-30 |
Taiga Biotechnologies, Inc. |
Production and use of red blood cells
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
GB201313377D0
(en)
|
2013-07-26 |
2013-09-11 |
Adaptimmune Ltd |
T cell receptors
|
|
EP3071594A4
(en)
|
2013-11-22 |
2017-05-03 |
The Board of Trustees of the University of Illionis |
Engineered high-affinity human t cell receptors
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
EP3082853A2
(en)
|
2013-12-20 |
2016-10-26 |
The Broad Institute, Inc. |
Combination therapy with neoantigen vaccine
|
|
GB201322798D0
(en)
|
2013-12-20 |
2014-02-05 |
Oxford Biomedica Ltd |
Production system
|
|
WO2015134787A2
(en)
|
2014-03-05 |
2015-09-11 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
|
EP3590958A1
(en)
|
2014-03-14 |
2020-01-08 |
Immunocore Limited |
Tcr libraries
|
|
US11390921B2
(en)
|
2014-04-01 |
2022-07-19 |
Adaptive Biotechnologies Corporation |
Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
WO2016014725A1
(en)
|
2014-07-22 |
2016-01-28 |
The University Of Notre Dame Du Lac |
Molecular constructs and uses thereof
|
|
US10629318B1
(en)
|
2014-10-28 |
2020-04-21 |
Michelle Corning |
Neutron beam diffraction material treatment system
|
|
US9938026B1
(en)
|
2014-10-28 |
2018-04-10 |
Michelle Corning |
Energy beam propulsion system
|
|
US9711252B1
(en)
|
2014-10-28 |
2017-07-18 |
Michelle Corning |
High energy beam diffraction material treatment system
|
|
CA2966201A1
(en)
|
2014-10-29 |
2016-05-06 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
|
|
US10112994B2
(en)
|
2014-11-05 |
2018-10-30 |
Genentech, Inc. |
Methods of producing two chain proteins in bacteria
|
|
MX382952B
(es)
*
|
2014-11-05 |
2025-03-13 |
Genentech Inc |
Métodos de producción de proteínas de cadena doble en bacterias.
|
|
CN107223133B
(zh)
|
2014-11-07 |
2021-01-29 |
广东香雪精准医疗技术有限公司 |
一种可溶的异质二聚t细胞受体及其制法和应用
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
WO2016086029A1
(en)
|
2014-11-25 |
2016-06-02 |
Adaptive Biotechnologies Corporation |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
US10993997B2
(en)
|
2014-12-19 |
2021-05-04 |
The Broad Institute, Inc. |
Methods for profiling the t cell repertoire
|
|
CN105985427A
(zh)
*
|
2015-02-06 |
2016-10-05 |
广州市香雪制药股份有限公司 |
高亲和力ny-eso t细胞受体
|
|
CA2976580A1
(en)
|
2015-02-24 |
2016-09-01 |
Adaptive Biotechnologies Corp. |
Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
|
|
AU2016242967B2
(en)
|
2015-04-01 |
2021-07-01 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible T cell receptors specific for an antigenic target
|
|
CN113349159B
(zh)
*
|
2015-04-06 |
2022-11-11 |
瑞泽恩制药公司 |
非人动物中的人源化t细胞介导的免疫应答
|
|
TW202523682A
(zh)
|
2015-05-20 |
2025-06-16 |
美商博德研究所有限公司 |
共有之gata3相關之腫瘤特異性新抗原
|
|
CN106279404A
(zh)
*
|
2015-05-20 |
2017-01-04 |
广州市香雪制药股份有限公司 |
一种可溶且稳定的异质二聚tcr
|
|
CA3012607A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Crispr enzymes and systems
|
|
GB2592821B
(en)
|
2015-07-31 |
2022-01-12 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
WO2017044661A1
(en)
|
2015-09-09 |
2017-03-16 |
Immune Design Corp. |
Ny-eso-1 specific tcrs and methods of use thereof
|
|
GB201516275D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516265D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516277D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR libraries
|
|
GB201516274D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516269D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516272D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516270D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
KR20180085717A
(ko)
|
2015-09-24 |
2018-07-27 |
에이비비트로, 엘엘씨 |
친화성-올리고뉴클레오타이드 콘쥬게이트 및 그것의 사용
|
|
JP7341661B2
(ja)
|
2015-09-25 |
2023-09-11 |
アブビトロ, エルエルシー |
ネイティブに対合するt細胞受容体配列のt細胞受容体標的識別のための高スループットプロセス
|
|
US12241053B2
(en)
|
2015-10-09 |
2025-03-04 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
|
AU2016355178B9
(en)
|
2015-11-19 |
2019-05-30 |
Massachusetts Institute Of Technology |
Lymphocyte antigen CD5-like (CD5L)-interleukin 12B (p40) heterodimers in immunity
|
|
GB201520583D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520564D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520539D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
WO2018083505A1
(en)
|
2016-11-07 |
2018-05-11 |
Immunocore Limited |
Peptides
|
|
GB201520597D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520545D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520575D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201607534D0
(en)
|
2016-04-29 |
2016-06-15 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520562D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520559D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201604468D0
(en)
|
2016-03-16 |
2016-04-27 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520541D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520579D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520603D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520592D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520558D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520563D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201607535D0
(en)
|
2016-04-29 |
2016-06-15 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520565D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520546D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520542D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520595D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520567D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520550D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520536D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520543D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520557D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520568D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd |
Peptides
|
|
GB201520548D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520544D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520566D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
WO2017089786A1
(en)
|
2015-11-23 |
2017-06-01 |
Immunocore Limited |
Peptides
|
|
GB201520589D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520570D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201522592D0
(en)
|
2015-12-22 |
2016-02-03 |
Immunocore Ltd |
T cell receptors
|
|
AU2017206656B2
(en)
|
2016-01-10 |
2024-02-01 |
Neotx Therapeutics Ltd. |
Immunopotentiator enhanced superantigen mediated cancer immunotherapy
|
|
GB201604953D0
(en)
|
2016-03-23 |
2016-05-04 |
Immunocore Ltd |
T cell receptors
|
|
SMT202100564T1
(it)
|
2016-04-08 |
2022-01-10 |
Adaptimmune Ltd |
Recettori di cellule t
|
|
KR20190059874A
(ko)
|
2016-04-08 |
2019-05-31 |
어댑티뮨 리미티드 |
T 세포 수용체
|
|
PL3440105T3
(pl)
|
2016-04-08 |
2022-08-29 |
Immunocore Limited |
Receptory komórek t
|
|
CA3020555A1
(en)
|
2016-04-08 |
2017-10-12 |
Adaptimmune Limited |
T cell receptors
|
|
EP3443123B1
(en)
*
|
2016-04-11 |
2021-08-11 |
Board of Regents, The University of Texas System |
Methods and compositions for detecting single t cell receptor affinity and sequence
|
|
EP3446119A1
(en)
|
2016-04-18 |
2019-02-27 |
The Broad Institute Inc. |
Improved hla epitope prediction
|
|
WO2017208018A1
(en)
|
2016-06-02 |
2017-12-07 |
Immunocore Limited |
Dosing regimen for gp100-specific tcr - anti-cd3 scfv fusion protein
|
|
WO2018005559A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
|
US11630103B2
(en)
|
2016-08-17 |
2023-04-18 |
The Broad Institute, Inc. |
Product and methods useful for modulating and evaluating immune responses
|
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
BR112019005748A2
(pt)
|
2016-09-24 |
2019-06-18 |
Abvitro Llc |
afinidade-conjugados de oligonucleotídeo e usos destes
|
|
WO2018064208A1
(en)
|
2016-09-28 |
2018-04-05 |
The Broad Institute, Inc. |
Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof
|
|
CN110139873A
(zh)
|
2016-10-03 |
2019-08-16 |
朱诺治疗学股份有限公司 |
Hpv特异性结合分子
|
|
US12447213B2
(en)
|
2016-10-07 |
2025-10-21 |
The Broad Institute, Inc. |
Modulation of novel immune checkpoint targets
|
|
WO2018071565A1
(en)
*
|
2016-10-11 |
2018-04-19 |
Bluebird Bio, Inc. |
TCRa HOMING ENDONUCLEASE VARIANTS
|
|
BR112019006652A2
(pt)
|
2016-10-13 |
2019-07-02 |
Juno Therapeutics Inc |
métodos e composições para imunoterapia envolvendo moduladores da via metabólica do triptofano
|
|
JP7181862B2
(ja)
|
2016-10-18 |
2022-12-01 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
腫瘍浸潤リンパ球および治療の方法
|
|
AU2017355544A1
(en)
|
2016-11-03 |
2019-05-16 |
Juno Therapeutics, Inc. |
Combination therapy of a T cell therapy and a BTK inhibitor
|
|
US20190292246A1
(en)
|
2016-11-03 |
2019-09-26 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia imhibitor
|
|
WO2018089386A1
(en)
|
2016-11-11 |
2018-05-17 |
The Broad Institute, Inc. |
Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action
|
|
CN110352068A
(zh)
|
2016-12-02 |
2019-10-18 |
南加利福尼亚大学 |
合成的免疫受体及其使用方法
|
|
KR20190092472A
(ko)
|
2016-12-02 |
2019-08-07 |
타이가 바이오테크놀로지스, 인코포레이티드 |
나노입자 제제
|
|
AU2017368332A1
(en)
|
2016-12-03 |
2019-06-13 |
Juno Therapeutics, Inc. |
Methods for modulation of CAR-T cells
|
|
BR112019011065A2
(pt)
|
2016-12-03 |
2019-10-01 |
Juno Therapeutics Inc |
métodos para determinação da dosagem de células t car
|
|
MA46995A
(fr)
|
2016-12-03 |
2019-10-09 |
Acerta Pharma Bv |
Méthodes et compositions pour l'utilisation de lymphocytes t thérapeutiques en association avec des inhibiteurs de kinase
|
|
AU2017370644A1
(en)
|
2016-12-05 |
2019-06-13 |
Juno Therapeutics, Inc. |
Production of engineered cells for adoptive cell therapy
|
|
MX2019008227A
(es)
|
2017-01-10 |
2020-08-17 |
Juno Therapeutics Inc |
Analisis epigenetico de terapia celular y metodos relacionados.
|
|
CN110198954A
(zh)
|
2017-01-13 |
2019-09-03 |
艾吉纳斯公司 |
与ny-eso-1结合的t细胞受体和其使用方法
|
|
MX2019008538A
(es)
|
2017-01-20 |
2019-11-05 |
Juno Therapeutics Gmbh |
Conjugados de superficie celular y composiciones y métodos celulares relacionados.
|
|
WO2018140391A1
(en)
|
2017-01-24 |
2018-08-02 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
EP3573648B1
(en)
|
2017-01-25 |
2023-11-22 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
WO2018148180A2
(en)
|
2017-02-07 |
2018-08-16 |
Immune Design Corp. |
Materials and methods for identifying and treating cancer patients
|
|
WO2018148671A1
(en)
|
2017-02-12 |
2018-08-16 |
Neon Therapeutics, Inc. |
Hla-based methods and compositions and uses thereof
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
US12163952B2
(en)
|
2017-02-27 |
2024-12-10 |
Juno Therapeutics, Inc. |
Determining toxicity risk in CAR T-cell therapy
|
|
SG11201908271WA
(en)
|
2017-03-14 |
2019-10-30 |
Juno Therapeutics Inc |
Methods for cryogenic storage
|
|
WO2018183908A1
(en)
|
2017-03-31 |
2018-10-04 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
EP3606518A4
(en)
|
2017-04-01 |
2021-04-07 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR DETECTION AND MODULATION OF IMMUNOTHERAPY RESISTANCE GENE SIGNATURE IN CANCER
|
|
EP3607319A1
(en)
|
2017-04-07 |
2020-02-12 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods
|
|
WO2018191558A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Modulation of epithelial cell differentiation, maintenance and/or function through t cell action, and markers and methods of use thereof
|
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
CN110709700A
(zh)
|
2017-04-14 |
2020-01-17 |
朱诺治疗学股份有限公司 |
评估细胞表面糖基化的方法
|
|
US20210293783A1
(en)
|
2017-04-18 |
2021-09-23 |
The General Hospital Corporation |
Compositions for detecting secretion and methods of use
|
|
US20200078404A1
(en)
|
2017-05-01 |
2020-03-12 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
|
EP3622092A4
(en)
|
2017-05-11 |
2021-06-23 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS OF USE OF CD8 + TUMOR-INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF
|
|
EP3625342B1
(en)
|
2017-05-18 |
2022-08-24 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
ES2926722T3
(es)
|
2017-05-26 |
2022-10-27 |
Abvitro Llc |
Secuenciación de alto rendimiento de biblioteca de polinucleótidos y análisis de transcriptoma
|
|
CN111201438A
(zh)
|
2017-06-02 |
2020-05-26 |
朱诺治疗学股份有限公司 |
与和细胞疗法相关的毒性有关的制品和方法
|
|
AU2018275894B2
(en)
|
2017-06-02 |
2025-04-24 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
GB201709866D0
(en)
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
EP3644721A1
(en)
|
2017-06-29 |
2020-05-06 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
|
WO2019006418A2
(en)
|
2017-06-30 |
2019-01-03 |
Intima Bioscience, Inc. |
ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
BR112020001719A2
(pt)
|
2017-07-29 |
2020-07-21 |
Juno Therapeutics Inc |
reagentes para expansão de células que expressam receptores recombinantes
|
|
CN115028739A
(zh)
|
2017-08-03 |
2022-09-09 |
泰加生物工艺学公司 |
用于治疗黑素瘤的方法和组合物
|
|
US10149898B2
(en)
|
2017-08-03 |
2018-12-11 |
Taiga Biotechnologies, Inc. |
Methods and compositions for the treatment of melanoma
|
|
AU2018313950A1
(en)
|
2017-08-09 |
2020-02-13 |
Juno Therapeutics, Inc. |
Methods for producing genetically engineered cell compositions and related compositions
|
|
CN111263641B
(zh)
|
2017-08-09 |
2025-10-31 |
朱诺治疗学股份有限公司 |
用于制备基因工程化细胞的方法和组合物
|
|
WO2019046832A1
(en)
|
2017-09-01 |
2019-03-07 |
Juno Therapeutics, Inc. |
GENE EXPRESSION AND EVALUATION OF RISK OF DEVELOPMENT OF TOXICITY FOLLOWING CELL THERAPY
|
|
KR20200052327A
(ko)
|
2017-09-04 |
2020-05-14 |
아게누스 인코포레이티드 |
혼합 계통 백혈병 (mll)-특이적 포스포펩타이드에 결합하는 t 세포 수용체 및 그것의 사용 방법
|
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
|
JP2020535802A
(ja)
|
2017-09-21 |
2020-12-10 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
標的化核酸編集のための系、方法、及び組成物
|
|
AU2018337142B2
(en)
|
2017-09-22 |
2025-07-03 |
Wuxi Biologics Ireland Limited. |
Novel bispecific CD3/CD19 polypeptide complexes
|
|
CN117843810A
(zh)
*
|
2017-09-22 |
2024-04-09 |
上海药明生物技术有限公司 |
新型双特异性多肽复合物
|
|
EP3695408B1
(en)
|
2017-10-02 |
2026-01-21 |
The Broad Institute, Inc. |
Medical use of cdk4/6- and checkpoint-inhibitors in phased combination, in treatment of cancer
|
|
BR112020006643A2
(pt)
|
2017-10-03 |
2020-09-24 |
Juno Therapeutics Inc |
moléculas de ligação específica ao hpv
|
|
WO2019084055A1
(en)
|
2017-10-23 |
2019-05-02 |
Massachusetts Institute Of Technology |
CLASSIFICATION OF GENETIC VARIATION FROM UNICELLULAR TRANSCRIPTOMS
|
|
US11564946B2
(en)
|
2017-11-01 |
2023-01-31 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
EP3704230B1
(en)
|
2017-11-01 |
2024-10-23 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
SG11202003657VA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Process for producing a t cell composition
|
|
SG11202003427XA
(en)
|
2017-11-06 |
2020-05-28 |
Juno Therapeutics Inc |
Combination of a cell therapy and a gamma secretase inhibitor
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER BY TARGETING THE CLEC2D-KLRB1 PATH
|
|
EP3714041A1
(en)
|
2017-11-22 |
2020-09-30 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
US20210198372A1
(en)
|
2017-12-01 |
2021-07-01 |
Juno Therapeutics, Inc. |
Methods for dosing and for modulation of genetically engineered cells
|
|
JP7433230B2
(ja)
|
2017-12-08 |
2024-02-19 |
ジュノー セラピューティクス インコーポレイテッド |
細胞を培養するための無血清培地配合物およびその使用の方法
|
|
CA3084446A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Phenotypic markers for cell therapy and related methods
|
|
WO2019113557A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Process for producing a composition of engineered t cells
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
JPWO2019151392A1
(ja)
*
|
2018-01-31 |
2021-02-04 |
国立大学法人東北大学 |
抗原特異的mhc発現調節法
|
|
JP7383620B2
(ja)
|
2018-01-31 |
2023-11-20 |
セルジーン コーポレイション |
養子細胞療法およびチェックポイント阻害剤を使用する併用療法
|
|
CN111819194B
(zh)
|
2018-02-26 |
2024-06-04 |
基因医疗免疫疗法有限责任公司 |
Nyeso t细胞受体(tcr)
|
|
CA3094468A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
Methods of producing cells expressing a recombinant receptor and related compositions
|
|
AU2019249209A1
(en)
|
2018-04-05 |
2020-10-15 |
Juno Therapeutics, Inc. |
T cell receptors and engineered cells expressing same
|
|
KR20210020873A
(ko)
|
2018-04-05 |
2021-02-24 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 τ 세포, 관련 폴리뉴클레오티드 및 방법
|
|
CA3096202A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating egfrviii expressing glioblastomas
|
|
CA3095757A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating glioblastomas
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
MX2020012124A
(es)
|
2018-05-14 |
2021-04-19 |
Immunocore Ltd |
Polipeptidos de unión bifuncional.
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
CN112585162B
(zh)
|
2018-08-06 |
2025-01-28 |
基因医疗免疫疗法有限责任公司 |
Ha-1特异性t细胞受体及其用途
|
|
CN110818802B
(zh)
*
|
2018-08-08 |
2022-02-08 |
华夏英泰(北京)生物技术有限公司 |
一种嵌合t细胞受体star及其应用
|
|
EA202190469A1
(ru)
|
2018-08-09 |
2021-06-28 |
Джуно Терапьютикс, Инк. |
Способы оценки интегрированных нуклеиновых кислот
|
|
CN113474450A
(zh)
|
2018-08-09 |
2021-10-01 |
朱诺治疗学股份有限公司 |
产生工程化细胞的方法以及所述工程化细胞的组合物
|
|
CN112888707B
(zh)
|
2018-08-16 |
2025-04-25 |
百欧恩泰美国公司 |
T细胞受体构建体及其用途
|
|
US12391685B2
(en)
|
2018-08-20 |
2025-08-19 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease target binding and uses thereof
|
|
US20210324357A1
(en)
|
2018-08-20 |
2021-10-21 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
|
US12460244B2
(en)
|
2018-08-20 |
2025-11-04 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease activity and uses thereof
|
|
MX2021002574A
(es)
|
2018-09-11 |
2021-06-08 |
Juno Therapeutics Inc |
Metodos para el analisis por espectrometria de masas de composiciones de celulas modificadas.
|
|
GB201815041D0
(en)
|
2018-09-14 |
2018-10-31 |
Scancell Ltd |
Epitopes
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
|
US20220170097A1
(en)
|
2018-10-29 |
2022-06-02 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
|
EP3874024A1
(en)
|
2018-10-31 |
2021-09-08 |
Juno Therapeutics GmbH |
Methods for selection and stimulation of cells and apparatus for same
|
|
EP3877054B1
(en)
|
2018-11-06 |
2023-11-01 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
|
US12466892B2
(en)
|
2018-11-08 |
2025-11-11 |
The Regents Of The University Of California |
Systems and methods for targeting cancer cells
|
|
WO2020097403A1
(en)
|
2018-11-08 |
2020-05-14 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
|
PL3886875T3
(pl)
|
2018-11-30 |
2024-09-09 |
Juno Therapeutics, Inc. |
Metody leczenia z wykorzystaniem adoptywnej terapii komórkowej
|
|
PL3886894T3
(pl)
|
2018-11-30 |
2024-07-01 |
Juno Therapeutics, Inc. |
Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej
|
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
AU2019404547B2
(en)
|
2018-12-21 |
2025-01-30 |
Biontech Us Inc. |
Method and systems for prediction of HLA class II-specific epitopes and characterization of CD4+ T cells
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
ES2974424T3
(es)
|
2019-01-17 |
2024-06-27 |
Immunocore Ltd |
Formulaciones
|
|
US20220162312A1
(en)
*
|
2019-01-28 |
2022-05-26 |
WuXi Biologics Ireland Limited |
Novel bispecific cd3/cd20 polypeptide complexes
|
|
GB201901305D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Specific binding molecules
|
|
GB201901306D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Multi-domain binding molecules
|
|
US20220133795A1
(en)
|
2019-03-01 |
2022-05-05 |
Iovance Biotherapeutics, Inc. |
Expansion of Tumor Infiltrating Lymphocytes From Liquid Tumors and Therapeutic Uses Thereof
|
|
WO2020186101A1
(en)
|
2019-03-12 |
2020-09-17 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
|
AU2020243431B2
(en)
|
2019-03-18 |
2025-12-18 |
Ludwig Institute For Cancer Research Ltd. |
A2/NY-ESO-1 specific T cell receptors and uses thereof
|
|
US20220142948A1
(en)
|
2019-03-18 |
2022-05-12 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
|
WO2020191365A1
(en)
|
2019-03-21 |
2020-09-24 |
Gigamune, Inc. |
Engineered cells expressing anti-viral t cell receptors and methods of use thereof
|
|
EP3714941A1
(en)
|
2019-03-27 |
2020-09-30 |
Medigene Immunotherapies GmbH |
Mage-a4 tcrs
|
|
GB201904328D0
(en)
|
2019-03-28 |
2019-05-15 |
Immunocore Ltd |
Specific binding molecules
|
|
TWI850360B
(zh)
|
2019-04-04 |
2024-08-01 |
德商梅迪基因免疫治療公司 |
黑色素瘤相關抗原1(magea1)特異性t細胞受體及其用途
|
|
WO2020210231A1
(en)
|
2019-04-08 |
2020-10-15 |
Taiga Biotechnologies, Inc. |
Compositions and methods for the cry opreservation of immune cells
|
|
AU2020265741A1
(en)
|
2019-05-01 |
2021-11-25 |
Editas Medicine, Inc. |
Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods
|
|
KR20220030933A
(ko)
|
2019-05-08 |
2022-03-11 |
메디진 이뮤노테라피스 게엠바하 |
조작된 t 세포
|
|
EP3969041A4
(en)
|
2019-05-14 |
2023-05-10 |
Taiga Biotechnologies, Inc. |
COMPOSITIONS AND METHODS FOR TREATMENT OF T-CELL DEPLETION
|
|
AU2020275142A1
(en)
|
2019-05-15 |
2021-12-16 |
Neotx Therapeutics Ltd. |
Cancer treatment
|
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
|
US20220226464A1
(en)
|
2019-05-28 |
2022-07-21 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
MX2021015125A
(es)
|
2019-06-07 |
2022-04-06 |
Juno Therapeutics Inc |
Cultivo automatizado de celulas t.
|
|
EP3983006A1
(en)
|
2019-06-12 |
2022-04-20 |
Juno Therapeutics, Inc. |
Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein
|
|
WO2021005108A1
(en)
|
2019-07-09 |
2021-01-14 |
Medigene Immunotherapies Gmbh |
Magea10 specific t cell receptors and their use
|
|
WO2021030627A1
(en)
|
2019-08-13 |
2021-02-18 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
|
US12480958B2
(en)
|
2019-08-13 |
2025-11-25 |
Immatics Biotechnologies Gmbh |
Method for the characterization of peptide:MHC binding polypeptides
|
|
US12421557B2
(en)
|
2019-08-16 |
2025-09-23 |
The Broad Institute, Inc. |
Methods for predicting outcomes and treating colorectal cancer using a cell atlas
|
|
JP2022545467A
(ja)
|
2019-08-22 |
2022-10-27 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法とzesteホモログ2エンハンサー(EZH2)阻害剤との併用療法および関連方法
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
EP4025598A1
(en)
|
2019-09-06 |
2022-07-13 |
Eli Lilly and Company |
Proteins comprising t-cell receptor constant domains
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US12195725B2
(en)
|
2019-10-03 |
2025-01-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating and detecting tissue specific TH17 cell pathogenicity
|
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
|
GB201915282D0
(en)
|
2019-10-22 |
2019-12-04 |
Immunocore Ltd |
Specific binding molecules
|
|
WO2021084050A1
(en)
|
2019-10-30 |
2021-05-06 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
|
US11844800B2
(en)
|
2019-10-30 |
2023-12-19 |
Massachusetts Institute Of Technology |
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
|
|
US12195723B2
(en)
|
2019-11-08 |
2025-01-14 |
The Broad Institute, Inc. |
Engineered antigen presenting cells and uses thereof
|
|
WO2021094752A1
(en)
|
2019-11-12 |
2021-05-20 |
Oxford Biomedica (Uk) Limited |
Production system
|
|
KR20220115569A
(ko)
|
2019-11-18 |
2022-08-17 |
얀센 바이오테크 인코포레이티드 |
돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
|
|
IL293393A
(en)
|
2019-12-06 |
2022-07-01 |
Juno Therapeutics Inc |
Cell therapy-related toxicity and response-related methods for the treatment of b-cell malignancies
|
|
US11865168B2
(en)
|
2019-12-30 |
2024-01-09 |
Massachusetts Institute Of Technology |
Compositions and methods for treating bacterial infections
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
US20230090117A1
(en)
|
2020-01-28 |
2023-03-23 |
Juno Therapeutics, Inc. |
Methods for t cell transduction
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
IL296103A
(en)
|
2020-03-05 |
2022-11-01 |
Neotx Therapeutics Ltd |
Methods and compositions for treating cancer with immune cells
|
|
WO2021190580A1
(en)
*
|
2020-03-26 |
2021-09-30 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Bispecific polypeptide complexes, compositions, and methods of preparation and use
|
|
GB202005779D0
(en)
|
2020-04-21 |
2020-06-03 |
Scancell Ltd |
Anti-tumour immune responses
|
|
CA3174332A1
(en)
|
2020-04-21 |
2021-10-28 |
Jason PERERA |
Tcr/bcr profiling
|
|
GB202006629D0
(en)
|
2020-05-05 |
2020-06-17 |
Immunocore Ltd |
Specific binding molecules
|
|
WO2021231661A2
(en)
|
2020-05-13 |
2021-11-18 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
|
JP7727662B2
(ja)
|
2020-05-13 |
2025-08-21 |
ジュノー セラピューティクス インコーポレイテッド |
臨床応答に関連する特徴量の特定方法およびその使用
|
|
EP4171616A1
(en)
|
2020-06-26 |
2023-05-03 |
Juno Therapeutics GmbH |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
US12295997B2
(en)
|
2020-07-06 |
2025-05-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
GB202010329D0
(en)
|
2020-07-06 |
2020-08-19 |
Immunocore Ltd |
Specific binding molecules
|
|
WO2022060904A1
(en)
|
2020-09-16 |
2022-03-24 |
Obsidian Therapeutics, Inc. |
Compositions and methods for expression of t-cell receptors with small molecule-regulated cd40l in t cells
|
|
CN116615446A
(zh)
|
2020-09-24 |
2023-08-18 |
基因医疗免疫疗法有限责任公司 |
Mage-a3特异性t细胞受体及其用途
|
|
EP4232071A4
(en)
|
2020-10-23 |
2024-08-28 |
Asher Biotherapeutics, Inc. |
FUSIONS WITH CD8 ANTIGEN-BINDING MOLECULES TO MODULATE IMMUNE CELL FUNCTION
|
|
GB202018395D0
(en)
|
2020-11-23 |
2021-01-06 |
Scancell Ltd |
Immunotherapy
|
|
US20240000834A1
(en)
|
2020-11-24 |
2024-01-04 |
Shanghai GenBase Biotechnology Co., Ltd. |
Ras mutant epitope peptide and t cell receptor recognizing ras mutant
|
|
GB202019019D0
(en)
|
2020-12-02 |
2021-01-13 |
Univ Oxford Innovation Ltd |
T cell receptors and uses thereof
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
US12275766B2
(en)
|
2020-12-23 |
2025-04-15 |
Janssen Biotech, Inc. |
Neoantigen peptide mimics
|
|
KR20230133878A
(ko)
*
|
2021-01-19 |
2023-09-19 |
우시 바이올로직스 아일랜드 리미티드 |
안정성 및 발현이 향상된 폴리펩티드 복합체
|
|
WO2022171032A1
(zh)
|
2021-02-10 |
2022-08-18 |
上海吉倍生物技术有限公司 |
Ras G13D突变体表位肽及识别Ras G13D突变体的T细胞受体
|
|
IL305393A
(en)
|
2021-02-25 |
2023-10-01 |
Alaunos Therapeutics Inc |
Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof
|
|
WO2022187280A1
(en)
|
2021-03-01 |
2022-09-09 |
Dana-Farber Cancer Institute, Inc. |
Personalized redirection and reprogramming of t cells for precise targeting of tumors
|
|
JP2024509853A
(ja)
|
2021-03-03 |
2024-03-05 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法およびdgk阻害剤の組合せ
|
|
KR20230159851A
(ko)
|
2021-03-22 |
2023-11-22 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 결정하는 방법
|
|
US20240181052A1
(en)
|
2021-03-29 |
2024-06-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
AU2022249328A1
(en)
|
2021-03-31 |
2023-09-21 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified mice comprising humanized cellular immune system components with improved diversity of tcrβ repertoire
|
|
EP4334361A1
(en)
|
2021-05-05 |
2024-03-13 |
Immatics Biotechnologies GmbH |
Antigen binding proteins specifically binding prame
|
|
US20250283037A1
(en)
|
2021-05-06 |
2025-09-11 |
Juno Therapeutics Gmbh |
Methods for stimulating and transducing t cells
|
|
WO2023288203A2
(en)
|
2021-07-12 |
2023-01-19 |
Ludwig Institute For Cancer Research Ltd |
T cell receptors specific for tumor-associated antigens and methods of use thereof
|
|
WO2023099606A1
(en)
|
2021-12-01 |
2023-06-08 |
Immunocore Limited |
Treatment of mage-a4 positive cancer
|
|
KR20240114759A
(ko)
|
2021-12-01 |
2024-07-24 |
이뮤노코어 리미티드 |
치료
|
|
JP2025504002A
(ja)
|
2022-01-28 |
2025-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
細胞組成物を製造する方法
|
|
US20250145950A1
(en)
|
2022-02-01 |
2025-05-08 |
Alaunos Therapeutics, Inc. |
Methods for Activation and Expansion of T Cells
|
|
KR20240149435A
(ko)
|
2022-02-20 |
2024-10-14 |
이뮤노코어 리미티드 |
Hiv 특이적 결합 분자
|
|
WO2023183344A1
(en)
|
2022-03-21 |
2023-09-28 |
Alaunos Therapeutics, Inc. |
Methods for identifying neoantigen-reactive t cell receptors
|
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
WO2023230548A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
US20250382640A1
(en)
|
2022-06-29 |
2025-12-18 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
CA3265218A1
(en)
|
2022-08-18 |
2024-02-22 |
Immunocore Ltd |
MAGE A4 SPECIFIC T LYMPHOCYTE RECEPTOR FUSION PROTEINS
|
|
KR20250051727A
(ko)
|
2022-08-18 |
2025-04-17 |
이뮤노코어 리미티드 |
멀티-도메인 결합 분자
|
|
MX2025001960A
(es)
|
2022-08-18 |
2025-05-02 |
Immunocore Ltd |
Moléculas de unión multidominio
|
|
KR20250051722A
(ko)
|
2022-08-18 |
2025-04-17 |
이뮤노코어 리미티드 |
멀티-도메인 결합 분자
|
|
WO2024050399A1
(en)
|
2022-09-01 |
2024-03-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes
|
|
CN120152717A
(zh)
|
2022-09-08 |
2025-06-13 |
朱诺治疗学股份有限公司 |
T细胞疗法和连续或间歇dgk抑制剂给药的组合
|
|
WO2024077256A1
(en)
|
2022-10-07 |
2024-04-11 |
The General Hospital Corporation |
Methods and compositions for high-throughput discovery ofpeptide-mhc targeting binding proteins
|
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
CN121100267A
(zh)
|
2022-12-09 |
2025-12-09 |
朱诺治疗学股份有限公司 |
使用全息成像预测细胞表型的机器学习方法
|
|
EP4634216A1
(en)
|
2022-12-16 |
2025-10-22 |
Repertoire Immune Medicines, Inc. |
T cell receptors binding hpv-16 epitopes
|
|
US12195534B2
(en)
|
2023-01-06 |
2025-01-14 |
Immunocore Limited |
Binding molecules
|
|
US12134647B2
(en)
|
2023-01-06 |
2024-11-05 |
Immunocore Limited |
Binding molecules
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
WO2024192141A1
(en)
|
2023-03-13 |
2024-09-19 |
Dana-Farber Cancer Institute, Inc. |
Treatment of cancers having a drug-resistant mesenchymal cell state
|
|
WO2024197072A2
(en)
|
2023-03-21 |
2024-09-26 |
Alaunos Therapeutics, Inc. |
Identification of neoantigen-reactive t cell receptors
|
|
KR20250169631A
(ko)
|
2023-04-18 |
2025-12-03 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 평가하기 위한 세포독성 검정
|
|
WO2024226838A2
(en)
|
2023-04-25 |
2024-10-31 |
The Brigham And Women's Hospital, Inc. |
Treatment of autoimmune diseases having a pathogenic t cell state
|
|
GB202306345D0
(en)
|
2023-04-28 |
2023-06-14 |
Immunocore Ltd |
Binding molecules
|
|
CN121464348A
(zh)
|
2023-05-23 |
2026-02-03 |
朱诺治疗学股份有限公司 |
T细胞的激活标记物和评估t细胞激活的方法
|
|
GB202311170D0
(en)
|
2023-07-20 |
2023-09-06 |
Univ Oxford Innovation Ltd |
Antigen binding polypeptides
|
|
WO2025040598A2
(en)
|
2023-08-18 |
2025-02-27 |
Immatics Biotechnologies Gmbh |
Peptides displayed by mhc for use in immunotherapy against different types of cancer
|
|
WO2025059533A1
(en)
|
2023-09-13 |
2025-03-20 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
WO2025094054A1
(en)
|
2023-11-01 |
2025-05-08 |
Immunocore Limited |
Method for purifying small multi-domain proteins
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|
|
WO2025208068A2
(en)
*
|
2024-03-29 |
2025-10-02 |
Biontech Us Inc. |
T cell receptor constructs and uses thereof
|
|
WO2025219955A1
(en)
*
|
2024-04-17 |
2025-10-23 |
BioNTech SE |
Soluble tcrs and methods of use thereof
|
|
EP4635976A1
(en)
|
2024-04-19 |
2025-10-22 |
Medigene Immunotherapies GmbH |
Constant uni-tabs
|
|
WO2025224084A1
(en)
|
2024-04-22 |
2025-10-30 |
Engimmune Therapeutics Ag |
Proteins comprising t cell receptor constant domains
|
|
GB202406990D0
(en)
|
2024-05-16 |
2024-07-03 |
Univ Oxford Innovation Ltd |
T cell receptors and uses thereof
|
|
NL2037811B1
(en)
|
2024-05-29 |
2025-12-12 |
Univ Oslo |
Treatment for Cancer
|
|
GB2641580A
(en)
|
2024-06-07 |
2025-12-10 |
T Therapeutics Ltd |
Tumour-transforming multispecific proteins
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|
|
WO2026046995A1
(en)
|
2024-08-28 |
2026-03-05 |
Pairx Bio Pte. Ltd |
T cell receptors and uses thereof
|
|
WO2026047601A1
(en)
|
2024-08-28 |
2026-03-05 |
BioNTech SE |
T-cell receptors (tcrs)
|
|
WO2026058153A2
(en)
|
2024-09-10 |
2026-03-19 |
BioNTech SE |
Hpv-16 t cell receptor uses and compositions thereof
|
|
WO2026078231A1
(en)
|
2024-10-11 |
2026-04-16 |
T-Therapeutics Limited |
Soluble non-aggregating immune ligand
|