DK1358332T3 - En serpin i Bifidobakterier - Google Patents

En serpin i Bifidobakterier

Info

Publication number
DK1358332T3
DK1358332T3 DK02718062T DK02718062T DK1358332T3 DK 1358332 T3 DK1358332 T3 DK 1358332T3 DK 02718062 T DK02718062 T DK 02718062T DK 02718062 T DK02718062 T DK 02718062T DK 1358332 T3 DK1358332 T3 DK 1358332T3
Authority
DK
Denmark
Prior art keywords
sequences
polypeptides
ncc2705
pertains
sequence
Prior art date
Application number
DK02718062T
Other languages
Danish (da)
English (en)
Inventor
Eduardo Schiffrin
Fabrizio Arigoni
Stephanie Blum
Michele Delley
Mark Alan Schell
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Application granted granted Critical
Publication of DK1358332T3 publication Critical patent/DK1358332T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C2220/00—Biochemical treatment
    • A23C2220/20—Treatment with microorganisms
    • A23C2220/202—Genetic engineering of microorganisms used in dairy technology
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
DK02718062T 2001-01-30 2002-01-30 En serpin i Bifidobakterier DK1358332T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01102050A EP1227152A1 (fr) 2001-01-30 2001-01-30 Souche bactérienne et genome de bifidobacterium

Publications (1)

Publication Number Publication Date
DK1358332T3 true DK1358332T3 (da) 2007-01-08

Family

ID=8176339

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02718062T DK1358332T3 (da) 2001-01-30 2002-01-30 En serpin i Bifidobakterier

Country Status (12)

Country Link
US (2) US7183101B2 (fr)
EP (3) EP1227152A1 (fr)
JP (2) JP4570329B2 (fr)
CN (3) CN100558896C (fr)
AT (1) ATE342986T1 (fr)
AU (3) AU2002249151A1 (fr)
CA (2) CA2435664C (fr)
DE (1) DE60215461T2 (fr)
DK (1) DK1358332T3 (fr)
ES (2) ES2274019T3 (fr)
PT (2) PT1360299E (fr)
WO (3) WO2002074798A2 (fr)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001241934A1 (en) 2000-03-03 2001-09-17 Beckman Coulter Inc. Multiplex hybridization system for identification of pathogenic mycobacterium and method of use
EP1227152A1 (fr) * 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Souche bactérienne et genome de bifidobacterium
EP1264893A1 (fr) 2001-06-08 2002-12-11 Teagasc Dairy Products Research Centre Biosynthèse de CLA par bifidobactéries
ATE423843T1 (de) 2001-12-03 2009-03-15 Kyowa Hakko Kogyo Kk Mutierte 6-phosphogluconat-dehydrogenase
EP1578946A4 (fr) 2002-08-23 2009-08-26 Du Pont Utilisation de produits d'amidon en production biologique par fermentation
EP2228379A1 (fr) 2003-04-25 2010-09-15 North Carolina State University Séquences d'acides nucléiques de lactobacillus acidophilus codant des homologues de protéine de surface et utilisations de celles-ci
US7407787B2 (en) 2003-06-23 2008-08-05 North Carolina State University Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof
US20050037395A1 (en) * 2003-06-27 2005-02-17 Douwe Van Sinderen Product
MXPA05010349A (es) 2003-06-30 2006-03-08 Clasado Inc Composicion novedosa de galactooligosacaridos y preparacion de la misma.
KR100492455B1 (ko) * 2003-09-26 2005-05-30 주식회사 비피도 로바타바이러스 억제활성을 갖는 신균주 비피도 박테리움 롱검 에이알81 및 이로부터 분리된 활성단백질
WO2005034971A2 (fr) * 2003-10-08 2005-04-21 Masami Moriyama Agent antiviral
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US7455992B2 (en) 2004-02-23 2008-11-25 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore
WO2005085478A2 (fr) * 2004-02-27 2005-09-15 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Detection and identification de mycobacterium et de nocardia au moyen du gene seca
US7459289B2 (en) 2004-03-08 2008-12-02 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
US7550576B2 (en) 2004-08-09 2009-06-23 North Carolina State University Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
JP4784224B2 (ja) * 2004-09-24 2011-10-05 味の素株式会社 糖鎖転移方法および糖鎖転移酵素
WO2006047680A2 (fr) 2004-10-27 2006-05-04 North Carolina State University Acides nucleiques de lactobacillus acidophilus et leurs procedes d'utilisation
US7495092B2 (en) 2005-01-14 2009-02-24 North Carolina State University Compositions comprising promoter sequences and methods of use
DK1856148T3 (da) * 2005-03-07 2013-05-21 Barbara Kofler Neuropeptider
CA2602693A1 (fr) * 2005-05-16 2006-11-23 Universite De Liege Espece bifidobacterienne probiotique
PL1885383T3 (pl) 2005-05-31 2017-06-30 Iams Europe B.V. Kocie probiotyczne bifidobakterie
BRPI0611493B1 (pt) 2005-05-31 2022-04-05 Alimentary Health Ltd. Lactobacilos probióticos felinos
GB0525857D0 (en) * 2005-12-20 2006-02-01 Product and process
GB0601901D0 (en) 2006-01-31 2006-03-08 Product and Process
GB0606112D0 (en) 2006-03-28 2006-05-03 Product and process
CN100389125C (zh) * 2006-05-30 2008-05-21 中国科学院昆明动物研究所 无指盘臭蛙丙精肽、基因和变异体
EP2124966B1 (fr) 2007-02-01 2015-09-09 IAMS Europe B.V. Procédé pour réduire l'inflammation et le stress chez un mammifère en utilisant de glucose, d'avocat ou d'extraits d'avocat
CN101273738B (zh) * 2007-03-28 2011-06-01 哈尔滨正方科技有限公司 在常温下保持高活菌数的调配型酸性乳饮料的制备方法
EP2522358B1 (fr) * 2007-06-27 2016-11-09 Laboratorios Ordesa, S.l. Peptides contres les infections par le rotavirus
EP2053122A1 (fr) * 2007-10-23 2009-04-29 Nestec S.A. Bifidobactérie tolérante au stress
US9730968B2 (en) 2008-04-17 2017-08-15 Anaeropharma Science, Inc. Therapeutic agent for ischemic diseases
CN101570755B (zh) * 2008-04-29 2011-09-28 中国农业科学院植物保护研究所 一种细菌源蛋白酶抑制剂新基因及其表达与应用
US9771199B2 (en) * 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US9232813B2 (en) * 2008-07-07 2016-01-12 The Iams Company Probiotic supplement, process for making, and packaging
CN102984955B (zh) * 2008-11-11 2015-01-07 营养健康有限公司 长双歧杆菌
JP5860396B2 (ja) * 2009-05-11 2016-02-16 ネステク ソシエテ アノニム ラクトバチルス・ジョンソニーＬａ１ＮＣＣ５３３（ＣＮＣＭＩ−１２２５）及び免疫障害
AU2009347008B2 (en) 2009-05-27 2013-08-15 Clasado Limited Method of preventing diarrhoea
EP2270134A1 (fr) * 2009-07-03 2011-01-05 Nestec S.A. Bifidobactérie résistante au stress oxydatif
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
PT2467032T (pt) * 2009-08-18 2018-04-04 Nestec Sa Composição nutricional compreendendo estirpes de bifidobacterium longum e que reduz os sintomas de alergia alimentar, especialmente em lactentes e crianças
JPWO2011027875A1 (ja) * 2009-09-03 2013-02-04 独立行政法人理化学研究所 腸管バリア機能改善剤
JP5600179B2 (ja) * 2009-11-11 2014-10-01 アリメンタリー、ヘルス、リミテッド ビフィズス菌株
AU2011206532B8 (en) 2010-01-14 2015-08-06 Inserm (Institut National De La Sante Et De La Recherche Medicale) Recombinant probiotic bacteria for the prevention and treatment of inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS)
EP2896695A3 (fr) * 2010-01-29 2015-09-23 Anaeropharma Science, Inc. Plasmide de transformation
US8755425B2 (en) * 2010-06-30 2014-06-17 Comtech Ef Data Corp. Method and system for transmission of identification via metadata for repeating relays using spread-spectrum technology
CN101880668B (zh) * 2010-05-07 2012-05-23 广西大学 一种编码丝氨酸蛋白酶抑制剂的基因及其应用
EP2397145A1 (fr) * 2010-06-18 2011-12-21 Nestec S.A. L. johnsonii La1, B. longum NCC2705 et troubles immunitaires
CN101884782B (zh) * 2010-06-29 2015-09-16 南昌大学 长双歧杆菌粘附抑制蛋白Aip在防治腹泻中的应用
US20180163325A1 (en) 2016-12-09 2018-06-14 Robert Wayne Glenn, Jr. Dissolvable fibrous web structure article comprising active agents
CA2803382C (fr) 2010-07-02 2015-03-31 The Procter & Gamble Company Procede de diffusion d'un agent actif
WO2012003351A2 (fr) 2010-07-02 2012-01-05 The Procter & Gamble Company Matériau de voile et ses procédés de fabrication
JP5859526B2 (ja) 2010-07-02 2016-02-10 ザ プロクター アンド ギャンブルカンパニー 活性剤不織布ウェブを含むフィラメント及びその製造方法
EP2449891A1 (fr) * 2010-11-05 2012-05-09 Nestec S.A. Préparations de yogourt à boire contenant des micro-organismes probiotiques sans réplication
GB201021399D0 (en) * 2010-12-16 2011-01-26 Genetic Analysis As Oligonucleotide probe set and methods of microbiota profiling
TWI487530B (zh) * 2011-01-10 2015-06-11 可產生高免疫激活反應之比菲德氏龍根菌分離株
EP2694662B1 (fr) * 2011-04-05 2020-01-08 Lallemand Hungary Liquidity Management LLC Procédés pour l'amélioration du rendement et de la production de produit dans un microorganisme par l'addition d'accepteurs d'électrons alternatifs
WO2013008881A1 (fr) * 2011-07-13 2013-01-17 株式会社アネロファーマ・サイエンス Agent thérapeutique pour une maladie ischémique
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
RU2527069C2 (ru) * 2011-11-08 2014-08-27 Автономная Некоммерческая Организация "Научно-исследовательский центр биотехнологи антибиотиков и других биологически активных веществ "БИОАН" СПОСОБ ВИДОВОЙ И ШТАММОВОЙ ИДЕНТИФИКАЦИИ БИФИДОБАКТЕРИЙ ФИЛОТИПА Bifidobacterium longum
WO2013130773A2 (fr) 2012-02-29 2013-09-06 Ethicon Endo-Surgery, Inc. Compositions de microbiota et leurs procédés associés
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
US9161957B2 (en) 2012-08-03 2015-10-20 Life Well Lived, Llc Compositions and methods for reducing blood alcohol content
ES2821383T3 (es) * 2012-10-17 2021-04-26 Enterome Firmas genéticas de trastornos inflamatorios relacionados con el hígado y la enfermedad de Crohn
FR2999933B1 (fr) * 2012-12-21 2020-01-31 Société des Produits Nestlé S.A. Utilisation de microorganismes probiotiques comme agent favorisant la synthese de melanine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US9861666B2 (en) * 2013-08-12 2018-01-09 Mansel Griffiths Antiviral methods and compositions comprising probiotic bacterial molecules
WO2015166640A1 (fr) * 2014-05-01 2015-11-05 株式会社アネロファーマ・サイエンス Cassette d'expression de polypeptide hétérogène
US10344093B2 (en) 2014-05-02 2019-07-09 Shinshu University Antibody gene expression-secretion system
CA2964480A1 (fr) 2014-10-31 2016-05-06 Whole Biome Inc. Procedes et compositions se rapportant a un traitement microbien et au diagnostic de troubles
JP6755465B2 (ja) * 2014-12-03 2020-09-16 株式会社アネロファーマ・サイエンス 共発現プラスミド
KR20170091157A (ko) 2014-12-23 2017-08-08 4디 파마 리서치 리미티드 피린 폴리펩티드 및 면역 조정
PL3065748T3 (pl) 2014-12-23 2018-07-31 4D Pharma Research Limited Szczep Bacteroides thetaiotaomicron i jego zastosowanie w zmniejszaniu zapalenia
WO2016105513A1 (fr) * 2014-12-23 2016-06-30 Evolve Biosystems Inc. Procédé pour la détection non invasive de bifidobactéries activées
GB201508860D0 (en) 2015-05-22 2015-07-01 Nat Univ Ireland Diagnostic method
EA201890050A1 (ru) 2015-06-15 2018-06-29 4Д Фарма Рисёрч Лимитед Композиции, содержащие бактериальные штаммы
SI3240554T1 (sl) 2015-06-15 2019-12-31 4D Pharma Research Limited, Blautia stercosis in wexlerae za uporabo v zdravljenju vnetnih in avtoimunskih bolezni
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MD3650033T2 (ro) 2015-06-15 2022-08-31 4D Pharma Res Ltd Compoziții conţinând tulpini bacteriene
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
AU2016357554B2 (en) 2015-11-20 2019-04-04 Cj Bioscience, Inc. Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EP3520801A1 (fr) 2016-03-04 2019-08-07 4D Pharma Plc Compositions comprenant des souches bactériennes de blautia pour le traitement de l'hypersensibilité viscérale
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
CN105694892A (zh) * 2016-03-16 2016-06-22 山东大学 一种表面带正电荷的CdSe量子点的制备方法
TW201821093A (zh) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
CN106478812B (zh) * 2016-10-21 2020-11-20 沈阳药科大学 丝氨酸蛋白酶抑制剂-3及其功能、制备方法和应用
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
MX380727B (es) 2017-01-27 2025-03-12 Procter & Gamble Composiciones en la forma de estructuras sólidas solubles que comprenden partículas aglomeradas efervescentes.
MX380853B (es) 2017-01-27 2025-03-12 Procter & Gamble Composiciones en la forma de estructuras solidas solubles
DK3609909T3 (da) 2017-04-11 2025-09-01 Kerry Group Services Int Ltd Laktaseenzymer med forbedret aktivitet ved lave temperaturer
US12435326B2 (en) 2017-04-11 2025-10-07 Kerry Group Services International Ltd Lactase enzymes with improved properties
EP4011906A3 (fr) 2017-04-11 2022-09-07 Chr. Hansen A/S Enzymes de lactase à propriétés améliorées
WO2018189238A1 (fr) 2017-04-11 2018-10-18 Chr. Hansen A/S Enzymes de lactase ayant des propriétés améliorées
CN110650723A (zh) 2017-05-16 2020-01-03 宝洁公司 可溶性固体结构形式的调理毛发护理组合物
JP7212945B2 (ja) 2017-05-22 2023-01-26 フォーディー ファーマ リサーチ リミテッド 細菌株を含む組成物
TW201907931A (zh) 2017-05-24 2019-03-01 英商4D製藥研究有限公司 包含細菌菌株之組合物
MD3804737T2 (ro) 2017-06-14 2022-10-31 4D Pharma Res Limited Compoziții care conțin tulpini bacteriene
WO2018229188A1 (fr) 2017-06-14 2018-12-20 4D Pharma Research Limited Compositions comprenant des souches bactériennes
CN115813955A (zh) 2017-06-14 2023-03-21 4D制药研究有限公司 包含细菌菌株的组合物
WO2019046646A1 (fr) 2017-08-30 2019-03-07 Whole Biome Inc. Methodes et compositions pour le traitement de troubles associés au microbiome
WO2019055940A1 (fr) * 2017-09-18 2019-03-21 Dupont Nutrition Biosciences Aps Enzymes riboflavinases et leur utilisation pour supprimer l'arôme lors du brassage
JP7811843B2 (ja) 2018-07-19 2026-02-06 ペンデュラム セラピューティクス， インコーポレイテッド 微生物生着のための方法および組成物
US11666514B2 (en) 2018-09-21 2023-06-06 The Procter & Gamble Company Fibrous structures containing polymer matrix particles with perfume ingredients
WO2020079116A1 (fr) * 2018-10-17 2020-04-23 Chr. Hansen A/S Enzymes de lactase ayant des propriétés améliorées à un ph acide
CN110343672B (zh) * 2018-12-27 2021-07-06 华东理工大学 一种抗尿苷酸反馈抑制的氨甲酰磷酸合成酶突变体及其应用
JP2021083433A (ja) * 2019-11-29 2021-06-03 地方独立行政法人神奈川県立産業技術総合研究所 抗原結合分子、核酸組成物、ベクター組成物、細胞およびＢｉｆｉｄｏｂａｃｔｅｒｉｕｍ ｌｏｎｇｕｍの精製方法
US11925698B2 (en) 2020-07-31 2024-03-12 The Procter & Gamble Company Water-soluble fibrous pouch containing prills for hair care
CN112458015B (zh) * 2020-11-27 2021-11-19 石家庄君乐宝乳业有限公司 长双歧杆菌长亚种i772、其分离纯化方法及应用
KR102314882B1 (ko) * 2021-01-29 2021-10-19 씨제이제일제당 (주) 신규한 막단백질 TerC 변이체 및 이를 이용한 L-라이신 생산 방법
EP4395730A1 (fr) 2021-08-30 2024-07-10 The Procter & Gamble Company Structure solide soluble comprenant des premier et second agents structurants polymères
CN113957073B (zh) * 2021-10-19 2023-09-01 山东寿光巨能金玉米开发有限公司 一种tkt基因启动子突变体及其在生产L-赖氨酸中的应用
EP4447893A1 (fr) 2021-12-17 2024-10-23 The Procter & Gamble Company Articles de shampooing fibreux solides solubles contenant des sels
WO2023173048A1 (fr) 2022-03-10 2023-09-14 The Procter & Gamble Company Structure solide soluble ayant des première et seconde couches
CN114774335B (zh) * 2022-06-22 2022-09-02 广东省科学院微生物研究所(广东省微生物分析检测中心) 具有靶向葡萄糖激酶显著降血糖和降血脂功效的长双歧杆菌070103及其应用
CN116334263B (zh) * 2023-04-21 2025-03-25 四川农业大学 一种用于检测鱼类鳃结节病病原菌的双重pcr引物、试剂盒及检测方法
CN116814822B (zh) * 2023-08-25 2023-11-24 中国食品发酵工业研究院有限公司 一种长双歧杆菌婴儿亚种cicc 6069菌株的鉴定方法和应用
CN117551799B (zh) * 2024-01-11 2024-03-19 广东海洋大学 用于鰤鱼诺卡氏菌菌株分型的引物组合、多重pcr鉴定方法及应用
CN118086539B (zh) * 2024-03-05 2024-10-01 中国食品发酵工业研究院有限公司 长双歧杆菌婴儿亚种的PMA-qPCR活菌定量检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62195823U (fr) * 1986-06-02 1987-12-12
JPH0687732B2 (ja) * 1987-02-25 1994-11-09 カルピス食品工業株式会社 ビフイズス菌入り発酵乳の製造法
ATE172245T1 (de) * 1992-07-06 1998-10-15 Nestle Sa Milchbakterien
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
CA2271720A1 (fr) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Polynucleotides et sequences de streptococcus pneumoniae
EP0981625A2 (fr) * 1997-05-06 2000-03-01 Human Genome Sciences, Inc. POLYNUCLEOTIDES ET POLYPEPTIDES D'$i(ENTEROCOCCUS FAECALIS)
JP4046389B2 (ja) * 1997-09-04 2008-02-13 株式会社ヤクルト本社 ビフィドバクテリウム・ブレーベ及びこれを用いた発酵豆乳
EP1227152A1 (fr) * 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Souche bactérienne et genome de bifidobacterium

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