|
US4137322A
(en)
*
|
1976-11-02 |
1979-01-30 |
Sankyo Company Limited |
ML-236B carboxylic acid derivatives and their use as antihyperlipemic agents
|
|
JPS53147073A
(en)
*
|
1977-05-24 |
1978-12-21 |
Sankyo Co Ltd |
Mevalonolactone derivatives
|
|
NZ191762A
(en)
*
|
1978-10-19 |
1982-09-14 |
Merck & Co Inc |
Hypocholesteremic composition containing cholesterol synthesis inhibitor and anion exchange resin
|
|
ZA795567B
(en)
*
|
1978-10-19 |
1981-06-24 |
Merck & Co Inc |
Treatment of hypercholesteremia
|
|
JPS5559180A
(en)
*
|
1978-10-30 |
1980-05-02 |
Sankyo Co Ltd |
4-hydroxy-2-pyrone ring compound, its preparation, and remedy for hyperlipemia comprising it as active constituent
|
|
JPS5925599B2
(ja)
|
1979-02-20 |
1984-06-19 |
三共株式会社 |
新生理活性物質モナコリンｋおよびその製造法
|
|
JPS55150898A
(en)
*
|
1979-05-11 |
1980-11-25 |
Sankyo Co Ltd |
Preparation of a new physiologically active substance mb-530b
|
|
US4319039A
(en)
*
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
US4231938A
(en)
*
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4294926A
(en)
*
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4710513A
(en)
*
|
1979-08-17 |
1987-12-01 |
Merck & Co., Inc. |
Substituted pyranone inhibitors of cholesterol synthesis
|
|
US4459422A
(en)
*
|
1979-08-17 |
1984-07-10 |
Merck & Co., Inc. |
Substituted pyranone inhibitors of cholesterol synthesis
|
|
US4375475A
(en)
*
|
1979-08-17 |
1983-03-01 |
Merck & Co., Inc. |
Substituted pyranone inhibitors of cholesterol synthesis
|
|
US4567289A
(en)
*
|
1979-08-17 |
1986-01-28 |
Merck & Co., Inc. |
Substituted pyranone inhibitors of cholesterol synthesis
|
|
US4294846A
(en)
*
|
1979-09-21 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and products of preparation
|
|
US4293496A
(en)
*
|
1980-02-04 |
1981-10-06 |
Merck & Co., Inc. |
6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones
|
|
PT72394B
(en)
*
|
1980-02-04 |
1982-09-06 |
Merck & Co Inc |
Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
|
|
US4282155A
(en)
*
|
1980-02-04 |
1981-08-04 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
AU548996B2
(en)
|
1980-02-04 |
1986-01-09 |
Merck & Co., Inc. |
Tetrahydro-2h-pyran-2-one derivatives
|
|
US4444784A
(en)
*
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
JPH0692381B2
(ja)
*
|
1980-03-31 |
1994-11-16 |
三共株式会社 |
Ｍｂ−５３０ａ誘導体
|
|
JPS56142236A
(en)
|
1980-04-08 |
1981-11-06 |
Sankyo Co Ltd |
Ml-236a and mb-530a derivative
|
|
US4322563A
(en)
*
|
1980-04-14 |
1982-03-30 |
Merck & Co., Inc. |
Substituted biphenyl-2-carboxaldehydes
|
|
JPS56150037A
(en)
*
|
1980-04-22 |
1981-11-20 |
Sankyo Co Ltd |
Hydronaphthalene compound
|
|
US4420491A
(en)
*
|
1980-05-28 |
1983-12-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
MX7065E
(es)
*
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
|
US4450171A
(en)
*
|
1980-08-05 |
1984-05-22 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4432996A
(en)
*
|
1980-11-17 |
1984-02-21 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
US4343814A
(en)
*
|
1980-11-17 |
1982-08-10 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
|
JPS57123140A
(en)
*
|
1981-01-23 |
1982-07-31 |
Sankyo Co Ltd |
Ml-236b carboxylic acid amine salt and remedy for hyperlipemia containing said salt as active component
|
|
JPS5815968A
(ja)
*
|
1981-07-21 |
1983-01-29 |
Sankyo Co Ltd |
Ｍｌ−２３６ｂ誘導体およびその製法
|
|
US4387242A
(en)
*
|
1981-08-21 |
1983-06-07 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
US4376863A
(en)
*
|
1981-08-21 |
1983-03-15 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
|
JPS5835144A
(ja)
*
|
1981-08-27 |
1983-03-01 |
Sankyo Co Ltd |
Ｍｂ−５３０ｂ誘導体およびその製造法
|
|
US5354772A
(en)
*
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4499289A
(en)
*
|
1982-12-03 |
1985-02-12 |
G. D. Searle & Co. |
Octahydronapthalenes
|
|
US4503072A
(en)
*
|
1982-12-22 |
1985-03-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
DE3480923D1
(de)
*
|
1983-10-11 |
1990-02-08 |
Merck & Co Inc |
Verfahren zur c-methylierung von 2-methylbutyraten.
|
|
US4584389A
(en)
*
|
1983-10-11 |
1986-04-22 |
Merck & Co., Inc. |
Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
|
|
US4582915A
(en)
*
|
1983-10-11 |
1986-04-15 |
Merck & Co., Inc. |
Process for C-methylation of 2-methylbutyrates
|
|
US4613610A
(en)
*
|
1984-06-22 |
1986-09-23 |
Sandoz Pharmaceuticals Corp. |
Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
|
|
US4804679A
(en)
*
|
1984-07-24 |
1989-02-14 |
Sandoz Pharm. Corp. |
Erythro-(E)-7-(3'-C1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
|
|
US4686237A
(en)
*
|
1984-07-24 |
1987-08-11 |
Sandoz Pharmaceuticals Corp. |
Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
|
|
US4647576A
(en)
*
|
1984-09-24 |
1987-03-03 |
Warner-Lambert Company |
Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
|
|
US5001255A
(en)
*
|
1984-12-04 |
1991-03-19 |
Sandoz Pharm. Corp. |
Idene analogs of mevalonolactone and derivatives thereof
|
|
US4668794A
(en)
*
|
1985-05-22 |
1987-05-26 |
Sandoz Pharm. Corp. |
Intermediate imidazole acrolein analogs
|
|
US4771071A
(en)
*
|
1986-05-05 |
1988-09-13 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4847306A
(en)
*
|
1986-05-05 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4766145A
(en)
*
|
1986-05-05 |
1988-08-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4864038A
(en)
*
|
1986-05-05 |
1989-09-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4681893A
(en)
*
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US5102893A
(en)
*
|
1986-07-07 |
1992-04-07 |
Warner-Lambert Company |
Trans-6-(2-(n-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl- or ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
|
|
US4957971A
(en)
*
|
1986-07-07 |
1990-09-18 |
Warner-Lambert Company |
Trans-6-(2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl)-or ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
|
|
US4678806A
(en)
*
|
1986-09-02 |
1987-07-07 |
Merck & Co., Inc. |
Prodrugs of antihypercholesterolemic compounds
|
|
US4904646A
(en)
*
|
1987-05-22 |
1990-02-27 |
E. R. Squibb & Sons, Inc. |
Phosphorus-containing HMG-COA reductase inhibitors
|
|
US5091378A
(en)
*
|
1987-05-22 |
1992-02-25 |
E. R. Squibb & Sons, Inc. |
Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
|
|
US4997848A
(en)
*
|
1987-10-27 |
1991-03-05 |
Sankyo Company, Limited |
Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
|
|
US4876280A
(en)
*
|
1988-03-10 |
1989-10-24 |
Sandoz Pharm. Corp. |
Arylcyclohexane and arylcyclohexene analogs of mevalonolactone derivatives and their use
|
|
US5180589A
(en)
*
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US5506219A
(en)
*
|
1988-08-29 |
1996-04-09 |
E. R. Squibb & Sons, Inc. |
Pyridine anchors for HMG-CoA reductase inhibitors
|
|
US4906657A
(en)
*
|
1988-12-21 |
1990-03-06 |
Warner-Lambert Company |
Bicyclo heptane and bicyclo octane substituted inhibitors of cholesterol synthesis
|
|
US4957940A
(en)
*
|
1988-12-21 |
1990-09-18 |
Warner-Lambert Company |
Bicyclo heptane and bicyclo octane substituted inhibitors of cholesterol synthesis
|
|
CA2007641A1
(en)
*
|
1989-02-01 |
1990-08-01 |
Donald S. Karanewsky |
Combination of squalene synthetase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination
|
|
US5001148A
(en)
*
|
1989-06-07 |
1991-03-19 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US4997849A
(en)
*
|
1989-06-23 |
1991-03-05 |
Merck & Co., Inc. |
Microbial transformation of simvastatin
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US5189180A
(en)
*
|
1989-09-28 |
1993-02-23 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
|
US5025017A
(en)
*
|
1989-09-28 |
1991-06-18 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
|
US5173487A
(en)
*
|
1989-11-13 |
1992-12-22 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US5264455A
(en)
*
|
1990-07-06 |
1993-11-23 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
WO1992019239A1
(en)
*
|
1991-05-01 |
1992-11-12 |
University Of New Mexico |
Treatment of aberrant cellular states with biomodulators
|
|
WO1992019240A1
(en)
*
|
1991-05-01 |
1992-11-12 |
University Of New Mexico |
Treatment of aberrant cellular states with biomodulators
|
|
US5286746A
(en)
*
|
1991-12-20 |
1994-02-15 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5620876A
(en)
*
|
1992-04-29 |
1997-04-15 |
E. R. Squibb & Sons, Inc. |
Enzymatic hydrolysis and esterification processes for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
FI932188L
(fi)
|
1992-05-15 |
1993-11-16 |
Sankyo Co |
Oktahydronaftalenoximderivat foer inhibering av kolesterolbiosyntesen, deras framstaellning och anvaendning
|
|
US5369123A
(en)
*
|
1992-10-09 |
1994-11-29 |
E. R. Squibb & Sons, Inc. |
Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA reductase inhibitors
|
|
US6190894B1
(en)
|
1993-03-19 |
2001-02-20 |
The Regents Of The University Of California |
Method and compositions for disrupting the epithelial barrier function
|
|
US5409820A
(en)
*
|
1993-08-06 |
1995-04-25 |
Apotex, Inc. |
Process for the production of lovastatin using Coniothyrium fuckelii
|
|
US6043064A
(en)
*
|
1993-10-22 |
2000-03-28 |
Bristol-Myers Squibb Company |
Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
AU1095695A
(en)
*
|
1993-11-09 |
1995-05-29 |
Brigham And Women's Hospital |
Hmg-coa reductase inhibitors in the normalization of vascular endothelial dysfunction
|
|
US6369103B1
(en)
*
|
1994-01-18 |
2002-04-09 |
Bristol-Myers Squibb Company |
Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
|
|
US6262277B1
(en)
*
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
|
US5942423A
(en)
|
1995-06-07 |
1999-08-24 |
Massachusetts Institute Of Technology |
Conversion of compactin to pravastatin by actinomadura
|
|
NZ280074A
(en)
*
|
1995-09-21 |
1997-05-26 |
Apotex Inc Substituted For Sco |
"compactin" produced by penicillium adametzioides g smith
|
|
US5763653A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Key intermediates in the manufacture of simvastatin
|
|
KR100186758B1
(ko)
|
1996-08-09 |
1999-04-01 |
영진약품공업 주식회사 |
프라바스타틴(pravastatin)전구체의제조방법
|
|
US7238348B2
(en)
*
|
1996-09-30 |
2007-07-03 |
Beijing Peking University Wbl Corporation Ltd. |
Method of treatment of osteoporosis with compositions of red rice fermentation products
|
|
US6046022A
(en)
|
1996-09-30 |
2000-04-04 |
Peking University |
Methods and compositions employing red rice fermentation products
|
|
US5763646A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Process for manufacturing simvastatin from lovastatin or mevinolinic acid
|
|
AU748608B2
(en)
*
|
1997-05-01 |
2002-06-06 |
Bristol-Myers Squibb Company |
MTP inhibitors and fat soluble vitamin therapeutic combinations to lower serum lipid levels
|
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
|
GT199800127A
(es)
*
|
1997-08-29 |
2000-02-01 |
|
Combinaciones terapeuticas.
|
|
US6177121B1
(en)
|
1997-09-29 |
2001-01-23 |
Purdue Research Foundation |
Composition and method for producing low cholesterol eggs
|
|
US6147109A
(en)
*
|
1997-10-14 |
2000-11-14 |
The General Hospital Corporation |
Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
|
|
US6083497A
(en)
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
|
US20080275104A1
(en)
*
|
1997-11-25 |
2008-11-06 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
US6180597B1
(en)
|
1998-03-19 |
2001-01-30 |
Brigham And Women's Hospital, Inc. |
Upregulation of Type III endothelial cell nitric oxide synthase by rho GTPase function inhibitors
|
|
US20030078211A1
(en)
*
|
1998-06-24 |
2003-04-24 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
WO1999067809A1
(en)
|
1998-06-24 |
1999-12-29 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US6423751B1
(en)
|
1998-07-14 |
2002-07-23 |
The Brigham And Women's Hospital, Inc. |
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
|
|
TR200100773T2
(tr)
|
1998-09-17 |
2001-07-23 |
Bristol-Myers Squibb Company |
Bir aP2 önleyicisinin ve kombinasyonunun kullanıldığı diyabet tedavi yöntemi
|
|
SK288117B6
(sk)
|
1998-11-20 |
2013-09-03 |
Skyepharma Canada Inc. |
Rapidly dispersing solid dry therapeutic dosage form
|
|
PL348508A1
(en)
*
|
1998-12-23 |
2002-05-20 |
Searle Llc |
Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
|
|
JP2002533410A
(ja)
*
|
1998-12-23 |
2002-10-08 |
ジー．ディー．サール エルエルシー |
心臓血管に適用するためのコレステリルエステル転送タンパク質阻害剤およびフィブリン酸誘導体の組み合わせ
|
|
AU2157400A
(en)
|
1998-12-23 |
2000-07-31 |
G.D. Searle & Co. |
Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
|
|
US6489366B1
(en)
*
|
1998-12-23 |
2002-12-03 |
G. D. Searle, Llc |
Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
|
|
DE69911058T2
(de)
*
|
1998-12-23 |
2004-06-03 |
G.D. Searle Llc, Chicago |
Kombinationen einem ibat inhibitor und einem mtp inhibitor für kardiovaskuläre indikationen
|
|
JP2002533414A
(ja)
*
|
1998-12-23 |
2002-10-08 |
ジー．ディー．サール エルエルシー |
心臓血管に適用するための回腸胆汁酸輸送阻害剤および胆汁酸隔離剤の組み合わせ
|
|
EP1340510A1
(de)
|
1998-12-23 |
2003-09-03 |
G.D. Searle LLC. |
Kombinationen von Cholesteryl-Ester-Transfer-Protein-Inhibitoren und Gallensäure-Sequestriermittel für kardiovaskuläre Indikationen
|
|
CN1342090A
(zh)
*
|
1998-12-23 |
2002-03-27 |
G·D·瑟尔有限公司 |
适用于心血管疾病的回肠胆汁酸转运抑制剂和贝酸衍生物的组合
|
|
US6323021B1
(en)
*
|
1999-01-15 |
2001-11-27 |
Industrial Technology Research Institute |
Mutant strain of penicillium citrinum and use thereof for preparation of compactin
|
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
|
PL353199A1
(en)
*
|
1999-08-30 |
2003-11-03 |
Aventis Pharma Deutschland Gmbh |
Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
|
|
CO5251465A1
(es)
*
|
2000-01-26 |
2003-02-28 |
Pfizer Prod Inc |
Composiciones y procedimientos para tratar la osteoporosis y reducir el colesterol
|
|
HRP20020683A2
(en)
|
2000-02-24 |
2004-12-31 |
Biogal Gyogyszergyar |
Method of purifying a fermentation broth
|
|
WO2001068637A2
(en)
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Method for the preparation of tetrahydrobenzothiepines
|
|
AU2001247331A1
(en)
*
|
2000-03-10 |
2001-09-24 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
AU2000255633A1
(en)
*
|
2000-04-27 |
2001-11-07 |
Biocon India Limited |
A novel process for the manufacture and purification of compactin
|
|
DE10030375A1
(de)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
|
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
|
ZA200302507B
(en)
*
|
2000-10-12 |
2004-03-31 |
Nisaan Chemical Ind Ltd |
Preventives and remedies for complications of diabetes.
|
|
WO2002083066A2
(en)
|
2001-04-11 |
2002-10-24 |
Bristol-Myers Squibb Company |
Amino acid complexes of c-aryl glucosides for treatment of diabetes and method
|
|
US7642286B2
(en)
*
|
2001-06-21 |
2010-01-05 |
Andrx Pharmaceuticals, Inc. |
Stable pharmaceutical compositions containing pravastatin
|
|
US20040077625A1
(en)
*
|
2001-07-25 |
2004-04-22 |
Tremont Samuel J. |
Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
|
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
CA2463908A1
(en)
*
|
2001-10-18 |
2003-04-24 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
MXPA04003524A
(es)
*
|
2001-11-02 |
2004-07-23 |
Searle Llc |
Compuestos de benzotiepina monofluorados y difluorados novedosos como inhibidores de transporte de acido biliar co-dependiente de sodio apical (asbt) y captacion de taurocolato.
|
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
|
US20040142902A1
(en)
*
|
2001-11-08 |
2004-07-22 |
Struijker- Boudier Harry A.J. |
Implant dosage form and use thereof for the delivery of a cholosterol lowering agent
|
|
EP1443919A4
(de)
*
|
2001-11-16 |
2006-03-22 |
Bristol Myers Squibb Co |
Doppelte hemmer des adipozyten-fettsäure-bindungsproteins und des keratinozyten-fettsäure-bindungsproteins
|
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
BR0306643A
(pt)
|
2002-01-17 |
2004-10-19 |
Pharmacia Corp |
Novos compostos de hidroxi alquil/aril ou ceto tiepina como inibidores do transporte co-dependente de ácido biliar-sódio apical
|
|
KR100379075B1
(en)
*
|
2002-03-07 |
2003-04-08 |
Jinis Biopharmaceuticals Co |
Method for producing low cholesterol animal food product and food product therefrom
|
|
WO2003090723A1
(en)
*
|
2002-04-23 |
2003-11-06 |
Bristol-Myers Squibb Company |
Modified-release vasopeptidase inhibitor formulation, combinations and method
|
|
WO2003094845A2
(en)
|
2002-05-08 |
2003-11-20 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
|
WO2003096548A2
(de)
*
|
2002-05-14 |
2003-11-20 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
US20040132802A1
(en)
*
|
2002-09-03 |
2004-07-08 |
Jackie Butler |
Pharmaceutical formulations and methods for modified release of statin drugs
|
|
US20080293750A1
(en)
*
|
2002-10-17 |
2008-11-27 |
Anna Helgadottir |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
|
|
US20060019269A1
(en)
*
|
2002-10-17 |
2006-01-26 |
Decode Genetics, Inc. |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
|
|
DE60332856D1
(de)
*
|
2002-10-23 |
2010-07-15 |
Bristol Myers Squibb Co |
Auf glycinnitril basierende hemmer der dipeptidylpeptidase iv
|
|
US7098235B2
(en)
*
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
|
EP1961419B1
(de)
|
2002-12-20 |
2010-03-24 |
Pfizer Products Inc. |
Dosierungsform enthaltend einen CETP-Hemmer und einen HMG-CoA Reduktase Hemmer
|
|
WO2004066929A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Bristol-Myers Squibb Company |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
US20040248972A1
(en)
*
|
2003-05-16 |
2004-12-09 |
Ambit Biosciences Corporation |
Compounds and uses thereof
|
|
US20040242673A1
(en)
*
|
2003-05-16 |
2004-12-02 |
Ambit Biosciences Corporation |
Heterocyclic compounds and uses thereof
|
|
US20050182125A1
(en)
*
|
2003-05-16 |
2005-08-18 |
Ambit Biosciences Corporation |
Pyrrole compounds and uses thereof
|
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
|
US20050043272A1
(en)
*
|
2003-07-11 |
2005-02-24 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for hydrophobic drug delivery
|
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7250444B2
(en)
*
|
2003-08-11 |
2007-07-31 |
Pfizer Inc. |
Pyrrole-based HMG-CoA reductase inhibitors
|
|
EP1510208A1
(de)
*
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Metformin-Statin-Kombination enthaltende pharmazeutische Zusammensetzungen
|
|
US20050053664A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Eliezer Zomer |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
|
|
NZ547752A
(en)
*
|
2003-11-12 |
2009-12-24 |
Phenomix Corp |
Heterocyclic boronic acid compounds for inhibiting dipeptidyl peptidase-IV
|
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
CN1882327A
(zh)
|
2003-11-19 |
2006-12-20 |
症变治疗公司 |
含磷的新的拟甲状腺素药
|
|
WO2005053683A1
(en)
*
|
2003-11-26 |
2005-06-16 |
Duke University |
A method of preventing or treating glaucoma
|
|
MXPA06005915A
(es)
*
|
2003-12-05 |
2006-06-27 |
Warner Lambert Co |
N-alquil pirroles como inhibidores de la hmg-coa reductasa.
|
|
JPWO2005063294A1
(ja)
|
2003-12-30 |
2007-12-13 |
興和株式会社 |
γ−セクレターゼ複合体形成阻害剤
|
|
US20070161700A1
(en)
*
|
2004-12-28 |
2007-07-12 |
Kowa Company, Ltd. |
Inhibitor for the formation of y-secretase complex
|
|
US20100216863A1
(en)
*
|
2004-01-30 |
2010-08-26 |
Decode Genetics Ehf. |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
|
|
US8158362B2
(en)
*
|
2005-03-30 |
2012-04-17 |
Decode Genetics Ehf. |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
|
|
WO2005079314A2
(en)
*
|
2004-02-13 |
2005-09-01 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods used to treat acne and candida
|
|
EP1719525B1
(de)
|
2004-02-25 |
2014-12-10 |
Kowa Company, Ltd. |
Nukleartransferpromotor für cdc42 protein und screening-verfahren dafür
|
|
JP4711952B2
(ja)
*
|
2004-02-25 |
2011-06-29 |
興和株式会社 |
Ｒａｃタンパク質の核内移行促進剤及びそのスクリーニング方法
|
|
ES2239533B1
(es)
*
|
2004-03-01 |
2006-12-16 |
Ercros Industrial, S.A. |
Procedimiento para la obtencion de compactina.
|
|
US7932268B2
(en)
|
2004-03-05 |
2011-04-26 |
The Trustees Of The University Of Pennsylvania |
Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
|
|
US7262318B2
(en)
*
|
2004-03-10 |
2007-08-28 |
Pfizer, Inc. |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
|
EP1734819A1
(de)
*
|
2004-03-19 |
2006-12-27 |
Pro-Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren für das targeting von metastasierenden tumoren mit hilfe von mehrwertigen ligandgebundenen kohlenhydratpolymeren
|
|
KR100598326B1
(ko)
|
2004-04-10 |
2006-07-10 |
한미약품 주식회사 |
ＨＭＧ-ＣｏＡ 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
|
|
US20050288340A1
(en)
*
|
2004-06-29 |
2005-12-29 |
Pfizer Inc |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
CA2573848A1
(en)
*
|
2004-07-12 |
2006-02-16 |
Phenomix Corporation |
Constrained cyano compounds
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
US20110217412A1
(en)
*
|
2004-07-30 |
2011-09-08 |
Jinis Biopharmaceuticals Co. |
Cholesterol lowering supplement and low cholesterol egg produced by using the same
|
|
KR100637762B1
(ko)
*
|
2004-07-30 |
2006-10-23 |
주식회사 지니스 |
저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법
|
|
EP1773128A2
(de)
*
|
2004-08-02 |
2007-04-18 |
Pro-Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur verbesserung der chemotherapie mit mikrobiellen zytotoxinen
|
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
WO2006076598A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006076568A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Thiazolopyridines as cannabinoid receptor modulators
|
|
US7368458B2
(en)
*
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006078697A1
(en)
*
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006086464A2
(en)
*
|
2005-02-10 |
2006-08-17 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5ht modulators
|
|
US20070293535A1
(en)
*
|
2005-02-24 |
2007-12-20 |
Kowa Company, Ltd. |
Nuclear Transfer Promoter for Ddc42 Protein and Method of Screening the Dame
|
|
EP2527337A1
(de)
|
2005-04-14 |
2012-11-28 |
Bristol-Myers Squibb Company |
Hemmer des 11-Beta-Hydroxysteroid-Dehydrogenase-1-Enzyms
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US20060275356A1
(en)
*
|
2005-05-25 |
2006-12-07 |
Burgess James W |
Pharmaceutical compositions for treating or preventing coronary artery disease
|
|
WO2006127948A2
(en)
*
|
2005-05-26 |
2006-11-30 |
Bristol-Myers Squibb Company |
N-terminally modified glp-1 receptor modulators
|
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
TW200726765A
(en)
*
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
EP1919393A2
(de)
*
|
2005-09-01 |
2008-05-14 |
Prescient Medical, Inc. |
Auf eine vorrichtung beschichtete arzneimittel zur behandlung von empfindlichem plaque
|
|
WO2007035395A2
(en)
*
|
2005-09-16 |
2007-03-29 |
Virginia Commonwealth University Intellectual Property Foundation |
Therapeutic compositions comprising chorionic gonadotropins and hmg coa reductase inhibitors
|
|
EP1951220A2
(de)
*
|
2005-10-18 |
2008-08-06 |
Aegerion Pharmaceuticals |
Zusammensetzungen zur senkung der serumcholesterin- und/oder triglyceridwerte
|
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
|
US8618115B2
(en)
*
|
2005-10-26 |
2013-12-31 |
Bristol-Myers Squibb Company |
Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
|
|
EP1943215A2
(de)
|
2005-10-31 |
2008-07-16 |
Brystol-Myers Squibb Company |
Inhibitoren von dipeptidylpeptidase iv auf pyrrolidinyl-beta-aminoamidbasis und verfahren
|
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
|
EP1976873A2
(de)
*
|
2006-01-11 |
2008-10-08 |
Brystol-Myers Squibb Company |
Modulatoren des humanen glukagon-ähnlichen peptids 1 und ihre anwendung in der behandlung von diabetes und verwandten leiden
|
|
US7553836B2
(en)
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
US20090069275A1
(en)
*
|
2006-02-17 |
2009-03-12 |
Rocca Jose G |
Low flush niacin formulation
|
|
CA2569776A1
(en)
*
|
2006-02-17 |
2007-08-17 |
Kos Life Sciences, Inc. |
Low flush niacin formulation
|
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
|
US20070269503A1
(en)
*
|
2006-05-16 |
2007-11-22 |
James Walter Burgess |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
|
|
US20100022457A1
(en)
*
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
EP2089355A2
(de)
|
2006-11-01 |
2009-08-19 |
Brystol-Myers Squibb Company |
Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
|
|
WO2008059466A1
(en)
*
|
2006-11-17 |
2008-05-22 |
Ranbaxy Laboratories Limited |
Production of compactin using new mutant strain of pencillium citrinum atcc 38065
|
|
CA2673290A1
(en)
*
|
2006-12-21 |
2008-07-03 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor
|
|
MX2009009126A
(es)
*
|
2007-03-01 |
2009-10-28 |
Concourse Health Sciences Llc |
Isomeros de niacinato de inositol y usos de los mismos.
|
|
AR065670A1
(es)
|
2007-03-09 |
2009-06-24 |
Indigene Pharmaceuticals Inc |
Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
|
|
WO2008112887A1
(en)
*
|
2007-03-13 |
2008-09-18 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
AR065809A1
(es)
|
2007-03-22 |
2009-07-01 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
|
US8546394B2
(en)
|
2007-04-17 |
2013-10-01 |
Bristol-Myers Squibb Company |
Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
CN101754972A
(zh)
*
|
2007-05-18 |
2010-06-23 |
百时美施贵宝公司 |
Sglt2抑制剂的晶体结构及其制备方法
|
|
AU2008287542C1
(en)
|
2007-06-01 |
2015-01-22 |
The Trustees Of Princeton University |
Treatment of viral infections by modulation of host cell metabolic pathways
|
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
CN101808995A
(zh)
*
|
2007-07-27 |
2010-08-18 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
RU2443699C2
(ru)
*
|
2007-09-20 |
2012-02-27 |
Айрм Ллк |
Соединения и композиции в качестве модуляторов активности gpr119
|
|
ES2448839T3
(es)
|
2007-11-01 |
2014-03-17 |
Bristol-Myers Squibb Company |
Compuestos no esteroideos útiles como moderadores de la actividad del receptor de glucocorticoides AP-1 y/o NF-kappa b y uso de los mismos
|
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
ES2330184B1
(es)
|
2008-06-03 |
2010-07-05 |
Neuron Biopharma, S.A. |
Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
|
|
US20120046364A1
(en)
|
2009-02-10 |
2012-02-23 |
Metabasis Therapeutics, Inc. |
Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
|
|
SG174504A1
(en)
|
2009-03-27 |
2011-10-28 |
Bristol Myers Squibb Co |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
CN102686579A
(zh)
|
2009-10-09 |
2012-09-19 |
Irm责任有限公司 |
作为gpr119活性调节剂的化合物和组合物
|
|
CN102711738A
(zh)
|
2009-11-13 |
2012-10-03 |
百时美施贵宝公司 |
质量得以减小的二甲双胍制剂
|
|
EP3315124B1
(de)
|
2009-11-13 |
2021-01-06 |
Astrazeneca AB |
Zweischichtige tablettenformulierungen
|
|
JP5784623B2
(ja)
|
2009-11-13 |
2015-09-24 |
アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ |
速放性錠剤製剤
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
AR079336A1
(es)
*
|
2009-12-11 |
2012-01-18 |
Irm Llc |
Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
US8592396B2
(en)
|
2010-04-14 |
2013-11-26 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
|
CN103153288B
(zh)
|
2010-07-09 |
2017-02-15 |
詹姆斯·特林卡·格林 |
用于包括瑞格列净的短半衰期药物的组合立即/延迟释放递送系统
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
EP2626069A4
(de)
|
2010-10-06 |
2014-03-19 |
Univ Tokyo |
Prophylaktisches und/oder therapeutisches mittel gegen lymphödeme
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉－葡萄糖共同輸送體１與２之抑制劑的組合物與應用方法
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
BR112014016154A8
(pt)
|
2011-12-29 |
2017-07-04 |
Tufts College |
funcionalização de biomateriais para controlar respostas à regeneração e inflamação
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
PL3489226T3
(pl)
|
2012-11-20 |
2021-08-02 |
Lexicon Pharmaceuticals, Inc. |
Inhibitory kotransportera glukozowo-sodowego 1
|
|
MX2015014666A
(es)
|
2013-04-17 |
2016-03-01 |
Pfizer |
Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares.
|
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
|
JP6536871B2
(ja)
|
2013-12-02 |
2019-07-03 |
国立大学法人京都大学 |
Ｆｇｆｒ３病の予防および治療剤ならびにそのスクリーニング方法
|
|
EP3194024B1
(de)
|
2014-09-15 |
2020-08-05 |
The Board of Trustees of the Leland Stanford Junior University |
Abzielung auf aneurysma durch modulation von phagozytosesignalwegen
|
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
|
US11253588B2
(en)
|
2015-02-27 |
2022-02-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Combination therapy for treatment of coronary artery disease
|
|
EP3288584A2
(de)
|
2015-04-30 |
2018-03-07 |
President and Fellows of Harvard College |
Anti-ap2-antikörper und antigenbindemittel zur behandlung von stoffwechselerkrankungen
|
|
BR112019015107A2
(pt)
|
2017-01-23 |
2020-03-10 |
Dong Wha Pharm. Co., Ltd. |
Formulação de complexo compreendendo inibidor de hmg-coa redutase e clopidogrel
|
|
CA3063439A1
(en)
|
2017-05-30 |
2018-12-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Treatment of neuroinflammatory disease
|
|
EP3703756B1
(de)
|
2017-11-02 |
2022-04-20 |
Consejo Superior de Investigaciones Científicas (CSIC) |
Verwendung von statinen bei der überwindung der resistenz gegenüber beta-laktam-antibiotika in bakterienspezies, die mithilfe des mevalonatsynthesewegs isoprenoide synthetisieren
|
|
EP3824912A4
(de)
|
2018-07-19 |
2022-04-20 |
Kyoto University |
Aus pluripotenten stammzellen abgeleiteter plattenförmiger knorpel und verfahren zur herstellung von plattenförmigen knorpeln
|
|
BR112021000139A2
(pt)
|
2018-07-19 |
2021-04-06 |
Astrazeneca Ab |
Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
|
|
US10968192B2
(en)
|
2018-09-26 |
2021-04-06 |
Lexicon Pharmaceuticals, Inc. |
Crystalline solid forms of N-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)butanamide and methods of their synthesis
|
|
JP7224001B2
(ja)
|
2018-12-21 |
2023-02-17 |
国立大学法人京都大学 |
ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
|
|
SG11202107614PA
(en)
|
2019-01-18 |
2021-08-30 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2020243134A1
(en)
|
2019-05-27 |
2020-12-03 |
Immatics US, Inc. |
Viral vectors and their use in adoptive cellular therapy
|
|
US20230172996A1
(en)
|
2020-02-21 |
2023-06-08 |
Yoshikazu NAKAOKA |
Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
|
AU2021202643B2
(en)
|
2020-07-27 |
2023-02-02 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
|
US20230285376A1
(en)
|
2020-07-29 |
2023-09-14 |
Amryt Pharmaceuticals Inc. |
Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients
|
|
TW202227616A
(zh)
|
2020-08-21 |
2022-07-16 |
美商英麥提克斯股份有限公司 |
分離ｃｄ８＋選擇ｔ細胞的方法
|
|
US20250108065A1
(en)
|
2022-01-26 |
2025-04-03 |
Astrazeneca Ab |
Methods of treating prediabetes or reducing the risk of developing type 2 diabetes with dapagliflozin
|
|
WO2025147589A1
(en)
|
2024-01-05 |
2025-07-10 |
Osanni Bio, Inc. |
Implants, compositions, and methods for treating retinal diseases and disorders
|
|
WO2025168652A1
(en)
|
2024-02-05 |
2025-08-14 |
Astrazeneca Ab |
Azd-0780 in combination with a statin for use in lowering ldl-c levels and treating cardiovacular diseases
|
|
TW202602866A
(zh)
|
2024-03-20 |
2026-01-16 |
瑞典商阿斯特捷利康公司 |
Ｐｃｓｋ９抑制劑及其使用方法
|
|
TW202602886A
(zh)
|
2024-03-20 |
2026-01-16 |
瑞典商阿斯特捷利康公司 |
Ｐｃｓｋ９抑制劑及其使用方法
|
|
TW202539678A
(zh)
|
2024-03-20 |
2025-10-16 |
瑞典商阿斯特捷利康公司 |
Ｐｃｓｋ９抑制劑及其使用方法
|
|
WO2025238159A1
(en)
|
2024-05-16 |
2025-11-20 |
Astrazeneca Ab |
Combination therapy comprising azd0780 and ezetimibe
|