DK1365749T3 - Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til anvendelse i blöde gelformuleringer - Google Patents

Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til anvendelse i blöde gelformuleringer

Info

Publication number: DK1365749T3
Authority: DK; Denmark
Prior art keywords: active ingredient; pharmaceutically active; concentration; preparation; dosage
Prior art date: 2000-08-29

Application number

DK01984557T

Other languages

Danish (da)

English (en)

Inventor

Stephen Charles Tindal

Christopher Clive Webster

Josephine Christine Ferdinando

Jacqueline Carol Lewis

Original Assignee

Scherer Technologies Inc R P

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-29

Filing date

2001-08-28

Publication date

2007-06-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24606884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1365749(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-08-28 Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P

2007-06-04 Application granted granted Critical

2007-06-04 Publication of DK1365749T3 publication Critical patent/DK1365749T3/da

Links

238000000034 method Methods 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 3
238000009472 formulation Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 5
RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 2
CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 1
239000002552 dosage form Substances 0.000 abstract 1
239000007903 gelatin capsule Substances 0.000 abstract 1
229960001680 ibuprofen Drugs 0.000 abstract 1
229960000905 indomethacin Drugs 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
229960002009 naproxen Drugs 0.000 abstract 1
CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
229960005489 paracetamol Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK01984557T 2000-08-29 2001-08-28 Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til anvendelse i blöde gelformuleringer DK1365749T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/649,947 US6387400B1 (en)	2000-08-29	2000-08-29	Process for preparing pharmaceutical compositions for use with soft gelatin formulations
PCT/US2001/026711 WO2002017855A2 (en)	2000-08-29	2001-08-28	Process for preparing pharmaceutical compositions for use with soft gelatin formulations

Publications (1)

Publication Number	Publication Date
DK1365749T3 true DK1365749T3 (da)	2007-06-04

Family

ID=24606884

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01984557T DK1365749T3 (da)	2000-08-29	2001-08-28	Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til anvendelse i blöde gelformuleringer

Country Status (23)

Country	Link
US (1)	US6387400B1 (no)
EP (1)	EP1365749B1 (no)
JP (1)	JP4990474B2 (no)
KR (1)	KR100634571B1 (no)
CN (1)	CN1237959C (no)
AT (1)	ATE353009T1 (no)
AU (2)	AU2431702A (no)
BR (1)	BRPI0113539B8 (no)
CA (1)	CA2419993C (no)
CY (1)	CY1106542T1 (no)
CZ (1)	CZ299449B6 (no)
DE (2)	DE01984557T1 (no)
DK (1)	DK1365749T3 (no)
ES (1)	ES2206081T3 (no)
HU (1)	HU229381B1 (no)
MX (1)	MXPA03001762A (no)
NO (1)	NO333369B1 (no)
PL (1)	PL200398B1 (no)
PT (1)	PT1365749E (no)
SI (1)	SI1365749T1 (no)
TW (1)	TW589199B (no)
WO (1)	WO2002017855A2 (no)
ZA (1)	ZA200301007B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4226846B2 (ja) *	2002-06-07	2009-02-18	キャタレント・ジャパン株式会社	口腔内で崩壊可能なソフトカプセル剤
EP1684732A2 (en) *	2003-11-12	2006-08-02	Ranbaxy Laboratories Limited	Ibuprofen-containing soft gelatin capsules
US9241902B2 (en) *	2003-12-17	2016-01-26	R.P. Scherer Technologies, Llc	Chewable soft capsules containing ungelatinized starch
US20050137262A1 (en) *	2003-12-22	2005-06-23	Hu Patrick C.	Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
WO2005063219A2 (en) *	2003-12-23	2005-07-14	Ranbaxy Laboratories Limited	Ibuprofen-containing soft gelatin capsules
AU2005206084A1 (en) *	2004-01-09	2005-08-04	Wyeth	Microemulsions for pharmaceutical compositions
US20050249802A1 (en) *	2004-05-06	2005-11-10	The Procter & Gamble Company	Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients
WO2005123133A1 (en) *	2004-06-18	2005-12-29	Ranbaxy Laboratories Limited	A process for preparing ibuprofen soft gelatin capsules
WO2006007095A2 (en)	2004-06-30	2006-01-19	Albemarle Corporation	High ibuprofen content granules and their preparation and use
US20060088590A1 (en) *	2004-10-22	2006-04-27	Banner Pharmacaps, Inc.	Non-blooming gelatin and non-gelatin formulations
US8231896B2 (en) *	2004-11-08	2012-07-31	R.P. Scherer Technologies, Llc	Non-gelatin soft capsule system
US20070053868A1 (en)	2005-03-08	2007-03-08	Banner Pharmacaps, Inc.	Solvent system for enhancing the solubility of pharmaceutical agents
US20080269334A1 (en) *	2005-09-19	2008-10-30	Albemarle Corporation	Highly Concentrated Pourable Aqueous Solutions Of Potassium Ibuprofen, Their Preparation And Their Use
CN100404031C (zh) *	2006-03-13	2008-07-23	浙江万联药业有限公司	含葡萄糖酸锌、布洛芬和马来酸氯苯那敏的软胶囊组合物
US9629809B2 (en)	2008-07-21	2017-04-25	Si Group, Inc.	High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629806B2 (en) *	2008-07-21	2017-04-25	Si Group, Inc.	High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
ES2363964B1 (es)	2009-11-20	2012-08-22	Gp Pharm, S.A.	Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
CA2690488C (en)	2010-01-19	2013-06-11	Accucaps Industries Limited	Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
CN104083339A (zh) *	2014-08-04	2014-10-08	人福普克药业（武汉）有限公司	萘普生钠软胶囊及其制备方法
CN107951857B (zh) *	2017-11-29	2019-12-24	浙江安宝药业有限公司	布洛芬软胶囊
CA3100314A1 (en)	2018-05-16	2019-11-21	Bayer Healthcare Llc	High concentration suspension formulation for cold and flu soft gel capsule medications
WO2019224832A1 (en) *	2018-05-25	2019-11-28	Strides Shasun Limited	Process for preparing pharmaceutical compositions resulting in reduction in overall fill volume for use with soft gelatin formulations
CN108904465B (zh) *	2018-10-17	2021-02-26	石药集团恩必普药业有限公司	一种布洛芬药物制剂组合物及其制备方法
CN109820833B (zh) *	2019-04-01	2022-02-01	人福普克药业（武汉）有限公司	一种快速溶出的布洛芬软胶囊及其制备方法
BR112021021414A2 (pt) *	2019-04-26	2022-02-15	Scherer Technologies Llc R P	Composição do mini softgel de naproxeno
CN114667084B (zh) *	2019-10-09	2024-11-15	R.P.谢勒技术有限公司	非动物性软凝胶胶囊制剂、其制备方法及使用方法
US20220233452A1 (en) *	2021-01-25	2022-07-28	R.P. Scherer Technologies, Llc	Mini softgel naproxen composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2118040A (en)	1982-02-15	1983-10-26	Hoechst Uk Ltd	Oral anti-diabetic preparation
EP0173729B1 (fr)	1984-03-14	1990-10-17	Jérôme CORBIERE	Ppocede de solubilisation de principes actifs et compositions pharmaceutiques ainsi obtenues
DE3437599C2 (de)	1984-10-13	1987-04-16	Dolorgiet GmbH & Co KG, 5205 St Augustin	Ibuprofen enthaltende Weichgelatinekapseln
US5071643A (en) *	1986-10-17	1991-12-10	R. P. Scherer Corporation	Solvent system enhancing the solubility of pharmaceuticals for encapsulation
JP3121080B2 (ja)	1991-12-19	2000-12-25	アール・ピー・シーラーコーポレイション	カプセル封入用溶液
US5376688A (en)	1992-12-18	1994-12-27	R. P. Scherer Corporation	Enhanced solubility pharmaceutical solutions
JP4510156B2 (ja) *	1997-03-03	2010-07-21	サノフィーアベンティス	難溶性薬剤物質を含有する医薬製剤

2000
- 2000-08-29 US US09/649,947 patent/US6387400B1/en not_active Expired - Lifetime
2001
- 2001-08-28 EP EP01984557A patent/EP1365749B1/en not_active Expired - Lifetime
- 2001-08-28 AT AT01984557T patent/ATE353009T1/de active
- 2001-08-28 DE DE0001365749T patent/DE01984557T1/de active Pending
- 2001-08-28 CN CNB01814778XA patent/CN1237959C/zh not_active Expired - Lifetime
- 2001-08-28 JP JP2002522830A patent/JP4990474B2/ja not_active Expired - Lifetime
- 2001-08-28 AU AU2431702A patent/AU2431702A/xx active Pending
- 2001-08-28 DK DK01984557T patent/DK1365749T3/da active
- 2001-08-28 ES ES01984557T patent/ES2206081T3/es not_active Expired - Lifetime
- 2001-08-28 WO PCT/US2001/026711 patent/WO2002017855A2/en not_active Ceased
- 2001-08-28 HU HU0401224A patent/HU229381B1/hu unknown
- 2001-08-28 MX MXPA03001762A patent/MXPA03001762A/es active IP Right Grant
- 2001-08-28 AU AU2002224317A patent/AU2002224317B2/en not_active Expired
- 2001-08-28 PL PL365752A patent/PL200398B1/pl unknown
- 2001-08-28 CA CA002419993A patent/CA2419993C/en not_active Expired - Lifetime
- 2001-08-28 SI SI200130688T patent/SI1365749T1/sl unknown
- 2001-08-28 DE DE60126433T patent/DE60126433T2/de not_active Expired - Lifetime
- 2001-08-28 CZ CZ20030564A patent/CZ299449B6/cs not_active IP Right Cessation
- 2001-08-28 KR KR1020037002971A patent/KR100634571B1/ko not_active Expired - Lifetime
- 2001-08-28 PT PT01984557T patent/PT1365749E/pt unknown
- 2001-08-28 BR BRPI0113539A patent/BRPI0113539B8/pt not_active IP Right Cessation
2002
- 2002-01-17 TW TW091100669A patent/TW589199B/zh not_active IP Right Cessation
2003
- 2003-02-05 ZA ZA200301007A patent/ZA200301007B/xx unknown
- 2003-02-26 NO NO20030897A patent/NO333369B1/no not_active IP Right Cessation
2007
- 2007-04-26 CY CY20071100560T patent/CY1106542T1/el unknown

Also Published As

Publication number	Publication date
US6387400B1 (en)	2002-05-14
CN1237959C (zh)	2006-01-25
WO2002017855A2 (en)	2002-03-07
CY1106542T1 (el)	2012-01-25
AU2002224317B2 (en)	2004-09-02
PL200398B1 (pl)	2009-01-30
ES2206081T1 (es)	2004-05-16
HUP0401224A3 (en)	2008-04-28
EP1365749B1 (en)	2007-01-31
EP1365749A4 (en)	2005-09-07
DE60126433D1 (de)	2007-03-22
JP2004526664A (ja)	2004-09-02
PL365752A1 (en)	2005-01-10
CN1477953A (zh)	2004-02-25
CA2419993A1 (en)	2002-03-07
HK1056326A1 (en)	2004-02-13
ZA200301007B (en)	2004-02-13
BRPI0113539B1 (pt)	2017-05-09
NO20030897D0 (no)	2003-02-26
KR20030041982A (ko)	2003-05-27
CA2419993C (en)	2008-12-23
ES2206081T3 (es)	2007-10-01
MXPA03001762A (es)	2003-06-04
BRPI0113539B8 (pt)	2021-05-25
ATE353009T1 (de)	2007-02-15
TW589199B (en)	2004-06-01
CZ299449B6 (cs)	2008-07-30
SI1365749T1 (sl)	2007-06-30
KR100634571B1 (ko)	2006-10-16
HU229381B1 (en)	2013-11-28
DE01984557T1 (de)	2004-04-22
HUP0401224A2 (hu)	2004-11-29
EP1365749A2 (en)	2003-12-03
DE60126433T2 (de)	2007-11-15
WO2002017855A3 (en)	2003-09-25
JP4990474B2 (ja)	2012-08-01
NO333369B1 (no)	2013-05-13
AU2431702A (en)	2002-03-13
NO20030897L (no)	2003-02-26
BR0113539A (pt)	2003-07-15
PT1365749E (pt)	2007-03-30

Publication	Publication Date	Title
DK1365749T3 (da)	2007-06-04	Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til anvendelse i blöde gelformuleringer
BG66093B1 (bg)	2011-04-29	Състави с контролирано освобождаване, съдържащи нимесулид
GEP20063741B (en)	2006-02-10	Nonaryl-Heterocyclic NMDA/NR2B Antagonists
BR0008590A (pt)	2001-10-30	Agente de entrega polimérico, composição, formade unidade de dosagem, método para administrarum agente biologicamente ativo a um animalnecessitando o agente, método para preparar umacomposição; e composto
HRP20020045A2 (en)	2006-06-30	Oral liquid compositions
BR0108435A (pt)	2004-06-15	Formulação e uso de entecavir de baixa dose
GEP20033131B (en)	2003-12-25	Azabicycloalkanes as CCR5 Modulators, Pharmaceutical Compositions Containing the Same and Their Use for Treatment and Prevention of Diseases Caused by CCR5 Activity
ATE486587T1 (de)	2010-11-15	Formulierungen zur oralen verabreichung von wirkstoffen
ATE549015T1 (de)	2012-03-15	Pharmazeutische wirkstoffhaltige formulierung mit überzug
ATE298324T1 (de)	2005-07-15	Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel
AP2003002763A0 (en)	2003-03-31	Controlled release formulations for oral administration
BR0111678A (pt)	2003-06-03	Composições medicinais contendo derivados de propenona
TR200101928T2 (tr)	2001-11-21	Geliştirilmiş kararlılığa sahip bileşimler
CA2466770A1 (en)	2003-06-05	Liquid pharmaceutical formulations of acetaminophen and an alkali metal 1-lactate salt
GEP20043377B (en)	2004-04-13	Pharmaceutical Complex
PT1144420E (pt)	2004-04-30	Fosfatidilinositois sulfatados a sua preparacao e a sua utilizacao
MY133368A (en)	2007-11-30	Process for preparing pharmaceutical compositions for use with soft gelatin formulations
ATE194498T1 (de)	2000-07-15	Wasserfreies mittel auf lactulosebasis
AU2019203288A1 (en)	2019-12-12	Process for preparing pharmaceutical compositions resulting in reduction in overall fill volume for use with soft gelatin formulations
NO20001846L (no)	2000-04-10	Nye farmasøytisk aktive forbindelser, deres fremstilling og anvendelse som ECE-inhibitorer
MY145885A (en)	2012-05-15	Controlled release formulations for oral administration
DE50311479D1 (de)	2009-06-10	Pharmazeutische zusammensetzung, enthaltend oxcarbazepin mit kontrollierter wirkstofffreisetzung
NO964775L (no)	1993-01-27	Fast farmasöytisk adenosinholdig preparat
AR032486A1 (es)	2003-11-12	Proceso para preparar composiciones para utilizar con formulaciones de gelatina blanda