DK137085D0 - Fremgangsmaade og mellemprodukter til fremstilling af racematfattigepeptider - Google Patents

Fremgangsmaade og mellemprodukter til fremstilling af racematfattigepeptider

Info

Publication number
DK137085D0
DK137085D0 DK137085A DK137085A DK137085D0 DK 137085 D0 DK137085 D0 DK 137085D0 DK 137085 A DK137085 A DK 137085A DK 137085 A DK137085 A DK 137085A DK 137085 D0 DK137085 D0 DK 137085D0
Authority
DK
Denmark
Prior art keywords
denotes
obut
leu
formula
intermediates
Prior art date
Application number
DK137085A
Other languages
English (en)
Other versions
DK170820B1 (da
DK137085A (da
Inventor
Rainer Uhmann
Kurt Radscheit
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK137085D0 publication Critical patent/DK137085D0/da
Publication of DK137085A publication Critical patent/DK137085A/da
Application granted granted Critical
Publication of DK170820B1 publication Critical patent/DK170820B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK137085A 1984-03-27 1985-03-26 Fremgangsmåde og tripeptid til fremstilling af racematfattige peptider DK170820B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843411224 DE3411224A1 (de) 1984-03-27 1984-03-27 Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
DE3411224 1984-03-27

Publications (3)

Publication Number Publication Date
DK137085D0 true DK137085D0 (da) 1985-03-26
DK137085A DK137085A (da) 1985-09-28
DK170820B1 DK170820B1 (da) 1996-01-29

Family

ID=6231739

Family Applications (1)

Application Number Title Priority Date Filing Date
DK137085A DK170820B1 (da) 1984-03-27 1985-03-26 Fremgangsmåde og tripeptid til fremstilling af racematfattige peptider

Country Status (10)

Country Link
US (1) US4691008A (da)
EP (1) EP0156280B1 (da)
JP (1) JPH0686478B2 (da)
AT (1) ATE50267T1 (da)
CA (1) CA1278650C (da)
DE (2) DE3411224A1 (da)
DK (1) DK170820B1 (da)
ES (1) ES8607342A1 (da)
HU (1) HU197928B (da)
IL (1) IL74703A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608251A (en) * 1984-11-09 1986-08-26 Pitman-Moore, Inc. LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
US5191065A (en) * 1988-11-22 1993-03-02 Hoechst Aktiengesellschaft Process for the preparation of tripeptides
DE3839379A1 (de) * 1988-11-22 1990-05-23 Hoechst Ag Verfahren zur herstellung von tripeptiden
DE19527574A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung vona-(N,N-Dialkyl)-aminocaarbonsäureamiden
AUPO776897A0 (en) * 1997-07-09 1997-07-31 Csl Limited A method of achieving production gains in livestock and agents useful for same
AUPP807399A0 (en) 1999-01-08 1999-02-04 Csl Limited Improved immunogenic lhrh composition and methods relating thereto
DE10333042B4 (de) * 2003-07-21 2005-09-29 Clariant Gmbh Verfahren zur Herstellung von cyclischen Phosphonsäureanhydriden und deren Verwendung
CN112500455A (zh) * 2020-10-12 2021-03-16 湖南津安生物科技有限公司 一种多肽固液组合合成戈那瑞林的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953416A (en) * 1971-12-20 1976-04-27 Karl Folkers Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same
FR2238700B1 (da) * 1973-07-24 1977-10-14 Takeda Chemical Industries Ltd
CS180644B2 (en) * 1973-09-29 1978-01-31 Takeda Chemical Industries Ltd Process for preparing nonapeptides
US3915947A (en) * 1974-07-11 1975-10-28 Lilly Co Eli Des-{8 His{hu 2{b ,Gly{hu 10{b {9 -D-Ala{hu 6 {b LHRH ethylamide as an inhibitor of LHRH
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US3963691A (en) * 1974-10-07 1976-06-15 Merck & Co., Inc. Synthetic antigens of luteinizing hormone releasing hormone
US4272432A (en) * 1974-11-13 1981-06-09 American Home Products Corporation Claudogenic-interceptive nonapeptide
DE2649146A1 (de) * 1975-10-29 1977-05-12 Parke Davis & Co Nonapeptide
GB1524747A (en) * 1976-05-11 1978-09-13 Ici Ltd Polypeptide
US4101537A (en) * 1977-04-07 1978-07-18 Parke, Davis & Company Octapeptides and methods for their production
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
JPS57118563A (en) * 1981-01-14 1982-07-23 Takeda Chem Ind Ltd Indole derivative and preparation of peptide
US4481190A (en) * 1982-12-21 1984-11-06 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists

Also Published As

Publication number Publication date
DE3575931D1 (de) 1990-03-15
ES541535A0 (es) 1986-05-16
EP0156280A3 (en) 1987-10-21
HUT37445A (en) 1985-12-28
EP0156280A2 (de) 1985-10-02
DK170820B1 (da) 1996-01-29
IL74703A0 (en) 1985-06-30
CA1278650C (en) 1991-01-02
HU197928B (en) 1989-06-28
JPS60218399A (ja) 1985-11-01
US4691008A (en) 1987-09-01
JPH0686478B2 (ja) 1994-11-02
EP0156280B1 (de) 1990-02-07
ES8607342A1 (es) 1986-05-16
ATE50267T1 (de) 1990-02-15
IL74703A (en) 1988-11-30
DE3411224A1 (de) 1985-10-10
DK137085A (da) 1985-09-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired